Stochastic dynamics in computational biology:

The aim of this book is to provide a well-structured and coherent overview of existing mathematical modeling approaches for biochemical reaction systems, investigating relations between both the conventional models and several types of deterministic-stochastic hybrid model recombinations. Another ma...

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Hauptverfasser: Winkelmann, Stefanie (VerfasserIn), Schütte, Christof 1966- (VerfasserIn)
Format: Buch
Sprache:English
Veröffentlicht: Cham, Switzerland Springer [2020]
Schriftenreihe:Frontiers in applied dynamical systems: reviews and tutorials volume 8
Schlagworte:
Zusammenfassung:The aim of this book is to provide a well-structured and coherent overview of existing mathematical modeling approaches for biochemical reaction systems, investigating relations between both the conventional models and several types of deterministic-stochastic hybrid model recombinations. Another main objective is to illustrate and compare diverse numerical simulation schemes and their computational effort. Unlike related works, this book presents a broad scope in its applications, from offering a detailed introduction to hybrid approaches for the case of multiple population scales to discussing the setting of time-scale separation resulting from widely varying firing rates of reaction channels. Additionally, it also addresses modeling approaches for non well-mixed reaction-diffusion dynamics, including deterministic and stochastic PDEs and spatiotemporal master equations. Finally, by translating and incorporating complex theory to a level accessible to non-mathematicians, this book effectively bridges the gap between mathematical research in computational biology and its practical use in biological, biochemical, and biomedical systems
Beschreibung:Introduction.- Well-mixed stochastic reaction kinetics.- Population scaling.- Temporal scaling.- Spatial scaling.- Summary and Outlook.- Mathematical background
Beschreibung:XVIII, 272 Seiten Diagramme 448 grams
ISBN:9783030623869

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