Memory makes the brain: the biological machinery that uses experiences to shape individual brains

"The development of the young brain after birth and the emergence of cognitive capacities, mind, and individuality rest on the maturation of a dense net of synaptic connections between neurons. Memory Makes the Brain describes the dramatic, competitive elimination of surplus synapses that occur...

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Bibliographische Detailangaben
1. Verfasser: Hansel, Christian (VerfasserIn)
Format: Elektronisch E-Book
Sprache:English
Veröffentlicht: Singapore World Scientific 2021
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Online-Zugang:Volltext
Zusammenfassung:"The development of the young brain after birth and the emergence of cognitive capacities, mind, and individuality rest on the maturation of a dense net of synaptic connections between neurons. Memory Makes the Brain describes the dramatic, competitive elimination of surplus synapses that occur in the young, maturing brain - in a process called synaptic pruning that was discovered by pediatric neurologist Peter Huttenlocher in the 1970's at the University of Chicago. Explaining similarities between developmental pruning and learning processes in the adult brain, neurobiologist Christian Hansel offers a unique perspective on brain adaptation and plasticity throughout lifetime, at times weaving in personal accounts and memories. The cellular plasticity machinery that enables learning is known to be affected in brain developmental disorders such as autism. Memory Makes the Brain explains how both maturation and adult synaptic plasticity are deregulated in autism, and how we begin to trace back autism-typical behavioral abnormalities to such synaptopathies"--Publisher's website
Beschreibung:Mode of access: World Wide Web. - System requirements: Adobe Acrobat Reader
Acknowledgments -- Introduction -- Peter Huttenlocher and the discovery of synaptic pruning -- Why postnatal brain plasticity is needed : ilmitations of genetic blueprints -- What goes up must come down : synaptic potentiation and depression -- Across time : shared synaptic plasticity machinery in the developing and the adult brain -- Synaptopathies : synaptic dysfunction in autism -- The study of autism-resembling behaviors in mouse models -- The memory engram -- Limitations : the non-synaptic plasticity component -- Ensemble sequences, associative plasticity and the learning of causal relationships -- Plasticity and the shaping of individual brains -- Index
Beschreibung:1 online resource (x, 182 p.)
ISBN:9789811228810
9811228817

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