Pharmaceutical chemistry:
Gespeichert in:
Weitere Verfasser: | , |
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Format: | Buch |
Sprache: | English |
Veröffentlicht: |
Oxford
Oxford University Press
[2021]
|
Ausgabe: | Second edition |
Schlagworte: | |
Online-Zugang: | Inhaltsverzeichnis |
Beschreibung: | xiv, 433 Seiten Illustrationen, Diagramme |
ISBN: | 9780198779780 |
Internformat
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Datensatz im Suchindex
_version_ | 1804182262169731072 |
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CONTENTS
Mastering the material
About the editors
Contributors
Abbreviations
THE IMPORTANCE OF PHARMACEUTICAL CHEMISTRY
Jill Barber And Chris Rostron
Chemical structures and nomenclature
The human test tube
More test tubes: plants and microorganisms
Glass and plastic test tubes
From test tube to pharmaceutical
ORGANIC STRUCTURE AND BONDING
Alastair Mann
What is organic chemistry?
The shape of molecules
The electronic configuration of carbon
The shape of organic molecules
Intermolecular forces
Reaction types and the making and breaking of bonds
The principles of organic reaction mechanisms
STEREOCHEMISTRY AND DRUG ACTION
Rosaleen J Anderson, Adam Todd, Mark Ashton And Lauren Molyneux
Introduction
Constitutional isomerism
Conformational isomerism
Stereoisomerism
Protein folding diseases
xi
xiii
xiii
xiv
s}u3}U0)
fan PROPERTIES OF ALIPHATIC HYDROCARBONS
= Andrew J Hall
ms 41 Nomenclature 96
2 42 Physical properties of aliphatic hydrocarbons 104
43 Alkanes—preparation and chemical properties 107
4 4 Alkenes—preparation and chemical properties 109
45 Alkynes—-preparation and reactions 122
4 6 Hydrocarbons in pharmacy 131
ALCOHOLS, PHENOLS, ETHERS, ORGANIC HALOGEN COMPOUNDS, AND AMINES
Chris Rostron
51 The hydroxyl group 138
5 2 Polyhydric alcohols 146
5 3 Phenols 148
©
354 Ethers 153
amp;
z55 Haloatkanes and other organic halogen compounds 156
5 6 Aromatic halogen compounds 158
57 Polyhalogen compounds 159
5 8 Amines 160
5 9 Quaternary ammonium compounds 163
THE CARBONYL GROUP AND ITS CHEMISTRY
Matthew Ingram
61 Carbonyl structure and nomenclature 165
6 2 The power ofthe carbonyl group 169
6 3 Reactions of carbonyl compounds—nucleophilic attack on carbon 175
6 4 a-substitution reactions 191
6 5 Carbonyls in the body 200
6 6 Carbonyls in drugs—opportunities and problems 201
a nn nenn
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fT HALdVHD
INORGANIC CHEMISTRY IN PHARMACY
Geoff Hall
8 1 Concepts in inorganic chemistry
8 2 Metals: introduction
4 3 Group 1 metals
Group 2 metals
Period 4 metals
Precious metals
Phosphorus
Sulfur
Alex White And Andrew Evans
The unit of life: the cell
Nucleic acids and nucleosides
3 3 The instruction manual of life: the genetic code
©: How is our genetic cade protected and passed on?
9 5 What can happen when things go wrong?
9 6 Nucleoside derivatives as drugs
9 7 Current and future genetic therapies
PROTEINS AND ENZYMES
Alex White And Helen Burrell
10 1 Structure and function of proteins
10 2 Enzymes and enzyme inhibition
10 3 Proteins as drug targets
CARBOHYDRATES AND CARBOHYDRATE METABOLISM
Alex White And Helen Burrell
111 Structure of carbohydrates
11 2 Carbohydrate metabolism
11 3 Regulation of carbohydrate metabolism
LIPIDS
Alex White And Helen Burrell
121 Fatty acids
12 2 Triglycerides
42 3 Phospholipids
SIU94U0)
12 4 Steroids
12 5 Lipids as a source of energy
ORIGINS OF DRUG MOLECULES
Tim Snape
131 Drugs, dyes and cleaning fluid: similarities and differences
13 2 Natural products as drugs and medicines
13 3 Semi-synthetic drugs
13 4 Synthetic drugs
13 5 Genetic engineering and fermentation (biotechnology) for the production of drugs
ABSORPTION, DISTRIBUTION, METABOLISM AND EXCRETION
Chris Rostron
_ 144 Absorption
142 Distribution
4 3 Metabolism
14 4 Excretion
teeta Sai vat teense sensi me Since nese sites wt ay neal ne eds
ets
a
|
adam_txt |
m
Ei
od
me]
=~
m
A
D
€ U31LdVH)
CONTENTS
Mastering the material
About the editors
Contributors
Abbreviations
THE IMPORTANCE OF PHARMACEUTICAL CHEMISTRY
Jill Barber And Chris Rostron
Chemical structures and nomenclature
The human test tube
More test tubes: plants and microorganisms
Glass and plastic test tubes
From test tube to pharmaceutical
ORGANIC STRUCTURE AND BONDING
Alastair Mann
What is organic chemistry?
The shape of molecules
The electronic configuration of carbon
The shape of organic molecules
Intermolecular forces
Reaction types and the making and breaking of bonds
The principles of organic reaction mechanisms
STEREOCHEMISTRY AND DRUG ACTION
Rosaleen J Anderson, Adam Todd, Mark Ashton And Lauren Molyneux
Introduction
Constitutional isomerism
Conformational isomerism
Stereoisomerism
Protein folding diseases
xi
xiii
xiii
xiv
s}u3}U0)
fan PROPERTIES OF ALIPHATIC HYDROCARBONS
= Andrew J Hall
ms 41 Nomenclature 96
2 42 Physical properties of aliphatic hydrocarbons 104
43 Alkanes—preparation and chemical properties 107
4 4 Alkenes—preparation and chemical properties 109
45 Alkynes—-preparation and reactions 122
4 6 Hydrocarbons in pharmacy 131
ALCOHOLS, PHENOLS, ETHERS, ORGANIC HALOGEN COMPOUNDS, AND AMINES
Chris Rostron
51 The hydroxyl group 138
5 2 Polyhydric alcohols 146
5 3 Phenols 148
©
354 Ethers 153
amp;
z55 Haloatkanes and other organic halogen compounds 156
5 6 Aromatic halogen compounds 158
57 Polyhalogen compounds 159
5 8 Amines 160
5 9 Quaternary ammonium compounds 163
THE CARBONYL GROUP AND ITS CHEMISTRY
Matthew Ingram
61 Carbonyl structure and nomenclature 165
6 2 The power ofthe carbonyl group 169
6 3 Reactions of carbonyl compounds—nucleophilic attack on carbon 175
6 4 a-substitution reactions 191
6 5 Carbonyls in the body 200
6 6 Carbonyls in drugs—opportunities and problems 201
a nn nenn
m
=x
a
u
-
m
a
ray
cy
fT HALdVHD
INORGANIC CHEMISTRY IN PHARMACY
Geoff Hall
8 1 Concepts in inorganic chemistry
8 2 Metals: introduction
4 3 Group 1 metals
Group 2 metals
Period 4 metals
Precious metals
Phosphorus
Sulfur
Alex White And Andrew Evans
The unit of life: the cell
Nucleic acids and nucleosides
3 3 The instruction manual of life: the genetic code
©: How is our genetic cade protected and passed on?
9 5 What can happen when things go wrong?
9 6 Nucleoside derivatives as drugs
9 7 Current and future genetic therapies
PROTEINS AND ENZYMES
Alex White And Helen Burrell
10 1 Structure and function of proteins
10 2 Enzymes and enzyme inhibition
10 3 Proteins as drug targets
CARBOHYDRATES AND CARBOHYDRATE METABOLISM
Alex White And Helen Burrell
111 Structure of carbohydrates
11 2 Carbohydrate metabolism
11 3 Regulation of carbohydrate metabolism
LIPIDS
Alex White And Helen Burrell
121 Fatty acids
12 2 Triglycerides
42 3 Phospholipids
SIU94U0)
12 4 Steroids
12 5 Lipids as a source of energy
ORIGINS OF DRUG MOLECULES
Tim Snape
131 Drugs, dyes and cleaning fluid: similarities and differences
13 2 Natural products as drugs and medicines
13 3 Semi-synthetic drugs
13 4 Synthetic drugs
13 5 Genetic engineering and fermentation (biotechnology) for the production of drugs
ABSORPTION, DISTRIBUTION, METABOLISM AND EXCRETION
Chris Rostron
_ 144 Absorption
142 Distribution
4 3 Metabolism
14 4 Excretion
teeta Sai vat teense sensi me Since nese sites wt ay neal ne eds
ets
a |
any_adam_object | 1 |
any_adam_object_boolean | 1 |
author2 | Rostron, Chris Barber, Jill |
author2_role | edt edt |
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author_GND | (DE-588)1262276799 (DE-588)1230421041 |
author_facet | Rostron, Chris Barber, Jill |
building | Verbundindex |
bvnumber | BV047176064 |
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classification_tum | MED 960 |
ctrlnum | (OCoLC)1245331908 (DE-599)BVBBV047176064 |
discipline | Chemie / Pharmazie Medizin |
discipline_str_mv | Chemie / Pharmazie Medizin |
edition | Second edition |
format | Book |
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id | DE-604.BV047176064 |
illustrated | Illustrated |
index_date | 2024-07-03T16:44:36Z |
indexdate | 2024-07-10T09:04:45Z |
institution | BVB |
isbn | 9780198779780 |
language | English |
oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-032581463 |
oclc_num | 1245331908 |
open_access_boolean | |
owner | DE-91G DE-BY-TUM DE-11 DE-19 DE-BY-UBM DE-188 |
owner_facet | DE-91G DE-BY-TUM DE-11 DE-19 DE-BY-UBM DE-188 |
physical | xiv, 433 Seiten Illustrationen, Diagramme |
publishDate | 2021 |
publishDateSearch | 2021 |
publishDateSort | 2021 |
publisher | Oxford University Press |
record_format | marc |
spelling | Pharmaceutical chemistry edited by Chris Rostron, Jill Barber Second edition Oxford Oxford University Press [2021] xiv, 433 Seiten Illustrationen, Diagramme txt rdacontent n rdamedia nc rdacarrier Pharmazeutische Chemie (DE-588)4132158-3 gnd rswk-swf Pharmaceutical chemistry Pharmazeutische Chemie (DE-588)4132158-3 s DE-604 Rostron, Chris (DE-588)1262276799 edt Barber, Jill (DE-588)1230421041 edt Erscheint auch als Online-Ausgabe 978-0-19-108533-8 HEBIS Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=032581463&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
spellingShingle | Pharmaceutical chemistry Pharmazeutische Chemie (DE-588)4132158-3 gnd |
subject_GND | (DE-588)4132158-3 |
title | Pharmaceutical chemistry |
title_auth | Pharmaceutical chemistry |
title_exact_search | Pharmaceutical chemistry |
title_exact_search_txtP | Pharmaceutical chemistry |
title_full | Pharmaceutical chemistry edited by Chris Rostron, Jill Barber |
title_fullStr | Pharmaceutical chemistry edited by Chris Rostron, Jill Barber |
title_full_unstemmed | Pharmaceutical chemistry edited by Chris Rostron, Jill Barber |
title_short | Pharmaceutical chemistry |
title_sort | pharmaceutical chemistry |
topic | Pharmazeutische Chemie (DE-588)4132158-3 gnd |
topic_facet | Pharmazeutische Chemie |
url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=032581463&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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