Molecular imaging: basic principles and applications in biomedical research
"The area of molecular imaging has matured over the past decade and is still growing rapidly. Many concepts developed for molecular biology and cellular imaging have been successfully translated to in vivo imaging of intact organisms. Molecular imaging enables the study of processes at a molecu...
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
New Jersey
World Scientific
[2020]
|
| Ausgabe: | Third edition |
| Schlagworte: | |
| Online-Zugang: | UBR01 URL des Erstveröffentlichers |
| Zusammenfassung: | "The area of molecular imaging has matured over the past decade and is still growing rapidly. Many concepts developed for molecular biology and cellular imaging have been successfully translated to in vivo imaging of intact organisms. Molecular imaging enables the study of processes at a molecular level in their full biological context. Due to the high specificity of the molecular readouts the approach bears a high potential for diagnostics. It is fair to say that molecular imaging has become an indispensable tool for biomedical research and drug discovery and development today. This volume familiarizes the reader with the concepts of imaging and molecular imaging in particular. Basic principles of imaging technologies, reporter moieties for the various imaging modalities, and the design of targeted probes are described in the first part. The second part illustrates how these tools can be used to visualize relevant molecular events in the living organism. Topics covered include the studies of the biodistribution of reporter probes and drugs, visualization of the expression of biomolecules such as receptors and enzymes, and how imaging can be used for analyzing consequences of the interaction of a ligand or a drug with its molecular target by visualizing signal transduction, or assessing the metabolic, physiological, or structural response of the organism studied. The third edition has been extended considerably. This holds for the chapter on imaging modalities, which now includes sections on intravital microscopy and mass spectrometric imaging. All chapters have been updated and a new chapter on the challenges of translating molecular imaging solutions for clinical use has been added"--Publisher's website |
| Beschreibung: | 1 Online-Ressource (xxxi, 768 Seiten) Illustrationen, Diagramme |
| ISBN: | 9781786346858 1786346850 |
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| dewey-full | 616.07/54 |
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| dewey-ones | 616 - Diseases |
| dewey-raw | 616.07/54 |
| dewey-search | 616.07/54 |
| dewey-sort | 3616.07 254 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| discipline_str_mv | Medizin |
| edition | Third edition |
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| illustrated | Not Illustrated |
| index_date | 2024-07-03T16:30:24Z |
| indexdate | 2024-07-10T09:03:18Z |
| institution | BVB |
| isbn | 9781786346858 1786346850 |
| language | English |
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| physical | 1 Online-Ressource (xxxi, 768 Seiten) Illustrationen, Diagramme |
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| spelling | Rudin, Markus 1953- Verfasser (DE-588)109059972 aut Molecular imaging basic principles and applications in biomedical research Markus Rudin Third edition New Jersey World Scientific [2020] 1 Online-Ressource (xxxi, 768 Seiten) Illustrationen, Diagramme txt rdacontent c rdamedia cr rdacarrier "The area of molecular imaging has matured over the past decade and is still growing rapidly. Many concepts developed for molecular biology and cellular imaging have been successfully translated to in vivo imaging of intact organisms. Molecular imaging enables the study of processes at a molecular level in their full biological context. Due to the high specificity of the molecular readouts the approach bears a high potential for diagnostics. It is fair to say that molecular imaging has become an indispensable tool for biomedical research and drug discovery and development today. This volume familiarizes the reader with the concepts of imaging and molecular imaging in particular. Basic principles of imaging technologies, reporter moieties for the various imaging modalities, and the design of targeted probes are described in the first part. The second part illustrates how these tools can be used to visualize relevant molecular events in the living organism. Topics covered include the studies of the biodistribution of reporter probes and drugs, visualization of the expression of biomolecules such as receptors and enzymes, and how imaging can be used for analyzing consequences of the interaction of a ligand or a drug with its molecular target by visualizing signal transduction, or assessing the metabolic, physiological, or structural response of the organism studied. The third edition has been extended considerably. This holds for the chapter on imaging modalities, which now includes sections on intravital microscopy and mass spectrometric imaging. All chapters have been updated and a new chapter on the challenges of translating molecular imaging solutions for clinical use has been added"--Publisher's website Molecular probes Diagnostic imaging Imaging systems in medicine Biomedizin (DE-588)4647152-2 gnd rswk-swf Bildgebendes Verfahren (DE-588)4006617-4 gnd rswk-swf Molekularbiologie (DE-588)4039983-7 gnd rswk-swf Bildgebendes Verfahren (DE-588)4006617-4 s Biomedizin (DE-588)4647152-2 s Molekularbiologie (DE-588)4039983-7 s DE-604 Erscheint auch als Online-Ausgabe 978-1-78634-686-5 Erscheint auch als Druck-Ausgabe, Hardcover 978-1-78634-684-1 https://www.worldscientific.com/worldscibooks/10.1142/q0204#t=toc Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Rudin, Markus 1953- Molecular imaging basic principles and applications in biomedical research Molecular probes Diagnostic imaging Imaging systems in medicine Biomedizin (DE-588)4647152-2 gnd Bildgebendes Verfahren (DE-588)4006617-4 gnd Molekularbiologie (DE-588)4039983-7 gnd |
| subject_GND | (DE-588)4647152-2 (DE-588)4006617-4 (DE-588)4039983-7 |
| title | Molecular imaging basic principles and applications in biomedical research |
| title_auth | Molecular imaging basic principles and applications in biomedical research |
| title_exact_search | Molecular imaging basic principles and applications in biomedical research |
| title_exact_search_txtP | Molecular imaging basic principles and applications in biomedical research |
| title_full | Molecular imaging basic principles and applications in biomedical research Markus Rudin |
| title_fullStr | Molecular imaging basic principles and applications in biomedical research Markus Rudin |
| title_full_unstemmed | Molecular imaging basic principles and applications in biomedical research Markus Rudin |
| title_short | Molecular imaging |
| title_sort | molecular imaging basic principles and applications in biomedical research |
| title_sub | basic principles and applications in biomedical research |
| topic | Molecular probes Diagnostic imaging Imaging systems in medicine Biomedizin (DE-588)4647152-2 gnd Bildgebendes Verfahren (DE-588)4006617-4 gnd Molekularbiologie (DE-588)4039983-7 gnd |
| topic_facet | Molecular probes Diagnostic imaging Imaging systems in medicine Biomedizin Bildgebendes Verfahren Molekularbiologie |
| url | https://www.worldscientific.com/worldscibooks/10.1142/q0204#t=toc |
| work_keys_str_mv | AT rudinmarkus molecularimagingbasicprinciplesandapplicationsinbiomedicalresearch |