Drug development for cancer and diabetes: a path to 2030

"Drug Development for Cancer and Diabetes: A Path to 2030 focuses on new developments in the discovery of drugs for the treatment of cancer and diabetes. This new book presents important recent advances, emerging trends, and novel innovations for these two world-leading diseases. It is structur...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Weitere Verfasser: Saravanan, K. (Professor of zoology) (HerausgeberIn)
Format: Elektronisch E-Book
Sprache:English
Veröffentlicht: Burlington, ON, Canada Apple Academic Press 2020
Schlagworte:
Online-Zugang:Volltext
Zusammenfassung:"Drug Development for Cancer and Diabetes: A Path to 2030 focuses on new developments in the discovery of drugs for the treatment of cancer and diabetes. This new book presents important recent advances, emerging trends, and novel innovations for these two world-leading diseases. It is structured in two parts. Part I consists of chapters that explores cancer cell cycle checkpoints, cancer biomarkers, essential drug properties, stages in anti-cancer drug development, and various bioactives that are effective against cancer. Part II presents a complete coverage of important advances and research discoveries in antidiabetic drugs. It details the potentials of medicinal plants and phytocompounds as sources for antidiabetic drugs and highlights the ethnobotanical basis of the compounds. With chapters written by professionals in the field of phytochemistry and pharmacology from key institutions around the world, this volume provides a wide coverage and will be useful especially for scientists in pharmaceutical field. Key features: presents novel discoveries and mechanisms for the treatment of cancer and diabetes, details the role of plants for the treatment and management of cancer and diabetes, discusses the role of phytocompounds as ligands for cancer and diabetic targets, reviews plants and the potential of phytochemicals as antidiabetic and anticancer drugs, explores the green biosynthesis of nanoparticles and their efficiency in the treatment of diabetes and cancer."--
Beschreibung:Includes bibliographical references and index
Biomarkers for Screening of Premalignant Lesions and Therapeutic Surveillance / Chukwuebuka Egbuna -- Kinase Targets in Cancer Drug Discovery / S. Usha -- Essential Drug Properties and Stages in Anti-Cancer Drug Development / Andrew G. Mtewa, Duncan Sesaazi, Amanjotannu, and Serawit Deyno -- Plant Constituent as Anti-Cancer Drugs / T. Veni, T. Pushpanathan, and G. Vimala -- Anticancer Properties of Some Effective Phytochemicals / Murat Alan and Behnaz Aslanipour -- Therapeutic Aspects of Some Extracts and Purified Cardiac Glycosides Obtained From Nerium Oleander L / Behnaz Aslanipour and Murat Alan -- Challenging Compounds of Some Medicinal Plants Against Cancer / N. Shaista Jabeen, L. Jagapriya, B. Senthilkumar, and K. Devi -- Medicinal Plants as Therapeutic Agents in the Treatment of Cancer / Jaya Vikaskurhekar -- Cytotoxic, Apoptosis-Inducing Effects and Anti-Cancerous Drug Candidature of Jasmonates / T. Parth, S. Ramalingam, T. Sampark, and T. Vasudev --
- Apoptosis Activity of 1,2,-Benzene Dicarboxylic Acid Isolated From Andrographis Paniculata on KB, SiHa and IMR Cancer Cell Lines / P. Krishnamoorthy* and D. Kalaiselvan -- Anticancer Drug Discovery From the Indian Spice Box / M. V. N. L. Chaitanya, Santhivardhan Chinni, P. Ramalingam, and Y. Padmanabha Reddy -- Phytochemical Investigation and Evaluation of Anti-Breast Cancer Activity of Chloroform Extract of Tagetes Erecta / R. Arul Priya, K. Saravanan, and Chukwaebuka Egbuna -- Isolation, Identification and in Silico Evaluation of Anticancer Activity of Flavone From Pisum Sativum / R. Arul Priya, K. Saravanan, and P. Karuppannan -- Functional Lead Phytochemicals From the Rutaceae and Zingiferaceae Plants for Development of Anticancer Drugs / K. Saravanan, B. Umarani, V. Balan, P. Premalatha, and Bir Bahadur -- In Vitro Anticancer Activity of Biophytum Sensitivum on Liver Cancer Lines (HEPG2) / M.P. Santhi, K. Saravanan, and P. Karuppannan --
- Saffron and Its Active Ingredients: A Natural Product with Potent Anticancer Property / Ashutosh Gupta and Abhay K. Pandey -- Effects of Pterocarpus Marsupium in the Management of Type 2 Diabetes Mellitus / Priscilla Suresh -- Antidiabetic and Antihyperlipidemic Activities of Cyathea Nilgiriensis (Holttum) on STZ Induced Diabetic Rats / S. Elavarasi, G. Revathi, K. Saravanan, and Horne Iona Averal -- Antidiabetic Activity of Drug Loaded Chitosan Nanoparticle / G. Revathi, S. Elavarasi, and K. Saravanan -- Antidiabetic Activity of Silver Nanoparticles Biosynthesized Using Ventilago Maderaspatana Leaf Extract / P. Karuppannan, K. Saravanan, and Horne Iona Averal -- Hypoglycemic Activity of Biophytum Sensitivum Whole Plant Extracts on Alloxan Induced Diabetic Rats / C. Renuka, K. Saravanan, and P. Karuppannan -- Antidiabetic Activity of Ventilago Maderaspatana Leaf Extracts on STZ Induced Diabetic Rats / P. Karuppannan, K. Saravanan, and P. Premalatha --
- Isolation, Identification, and Molecular Docking of Antidiabetic Compounds of Cytheia Nilgiriensis (Holttum) / S. Elavarasi, G. Revathi, and K. Saravanan -- Antidiabetic Potentials of Major Indian Spices: A Review / Pratibha, Hema Lohani, S. Zafar Haider,* and Nirpendra K. Chauhan -- Aloe Species: Chemical Composition and Therapeutic Uses in Diabetic Treatment / Amit Kumar Singh, Ramesh Kumar, B. Umarani, and Abhay K. Pandey
Beschreibung:1 Online-Ressource
ISBN:9780429330490
0429330499
9781000639988
1000639983
9781000649949
1000649946
9781000644968
1000644960
DOI:10.1201/9780429330490

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