Alphaherpesviruses: molecular biology, host interactions and control
Gespeichert in:
| Hauptverfasser: | , |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
[Norfolk?,] UK
Caister Academic Press
[2020]
|
| Online-Zugang: | Inhaltsverzeichnis Klappentext |
| Beschreibung: | 632 Seiten Illustrationen, Diagramme |
| ISBN: | 9781913652555 |
Internformat
MARC
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| 245 | 1 | 0 | |a Alphaherpesviruses |b molecular biology, host interactions and control |c editors: Ekaterina E. Heldwein, Gregory A. Smith |
| 264 | 1 | |a [Norfolk?,] UK |b Caister Academic Press |c [2020] | |
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| 700 | 1 | |a Heldwein, Ekaterina E. |4 edt |4 wpr |4 aut | |
| 700 | 1 | |a Smith, Gregory A. |4 edt |4 wpr |4 aut | |
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Datensatz im Suchindex
| _version_ | 1804182013555507200 |
|---|---|
| adam_text | Contents 1 Alphaherpesvirus Genomics: Past, Present and Future............................... 1 Chad V. Кипу and Moriah L. Szpara 2 Entry of Alphaherpesviruses........................................................................ 41 Tina M. Cairns and Sarah A. Connolly 3 Navigating the Cytoplasm: Delivery of the Alphaherpesvirus Genome to the Nucleus................................................................................ 103 Gregory A. Smith 4 The Fate of Incoming HSV-1 Genomes Entering the Nucleus................... 153 Oren Kobiler and Amichay Afriat 5 Invasion of the Nervous System...................................................................199 Orkide O. Koyuncu, Lynn W. Enquist and Esteban A. Engel 6 Alphaherpesvirus Latency and Reactivation with a Focus on Herpes Simplex Virus................................................................................... 261 Nancy M. Sawtell and Richard L. Thompson 7 Host Innate Immune Response and Viral Immune Evasion During Alphaherpesvirus Infection................................................................351 Krystal K. Lum and Ileana M. Cristea 8 Nuclear Egress.............................................................................................. 403 Elizabeth B. Draganova, Michael K. Thorsen and Ekaterina E. Heldwein 9 Tegument Assembly, Secondary Envelopment andExocytosis.................. 449 Ian B. Hogue 10 Alphaherpesvirus Vaccines........................................................................... 505 Clare Burn Aschner and Betsy C. Herold 11 Oncolytic HSV Vectors and Anti-Tumor
Immunity......................................545 Joseph C. Glorioso, Justus B. Cohen, William F. Goins, Bonnie Hall, Joseph W. Jackson, Gary Kohanbash, Nduka Amankulor, Balveen Kaur, Michael A. Caligiuri, E. Antonio Chiocca, Eric C. Holland and Christophe Quéva
Alphaherpesviruses encompass a broad group of pathogens including neuroinvasive viruses that establish lifelong infections in the peripheral nervous system of humans and many other vertebrates. One prominent example are herpes simplex viruses that infect most humans and can cause diseases ranging from painful skin ulcers to deadly encephalitis. For decades, researchers have been asking what makes these viruses neurotropic, how they establish a latent state, and why these typically benign infections can sometimes have severe or lethal outcomes. Since the last edition of this volume in 2011. our understanding of the alphaherpesviruses has significantly advanced creating the need for this new book that distils the most important new information to provide a timely overview. Chapters are written by well-respected researchers, each offering their perspectives on the current state of the field, using herpes simplex virus as the main focus. Topics covered include: genomics: entry into the cell: genome delivery from the cell periphery to the nucleus: the fate of the genome in the nucleus: infection of neurons: establishment of latency: host cellular responses to infection: viral immune evasion strategies: capsid egress from the nucleus: virion assembly in the cytoplasm: vaccines: oncolytic vectors. This book is essential reading for students, virologists, immunologists, medical and veterinary professionals and scientists working on neuroinvasive alphaherpesviruses. It is also a recommended reading for anyone with an interest in neurovirology and persistent viral infections.
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| adam_txt |
Contents 1 Alphaherpesvirus Genomics: Past, Present and Future. 1 Chad V. Кипу and Moriah L. Szpara 2 Entry of Alphaherpesviruses. 41 Tina M. Cairns and Sarah A. Connolly 3 Navigating the Cytoplasm: Delivery of the Alphaherpesvirus Genome to the Nucleus. 103 Gregory A. Smith 4 The Fate of Incoming HSV-1 Genomes Entering the Nucleus. 153 Oren Kobiler and Amichay Afriat 5 Invasion of the Nervous System.199 Orkide O. Koyuncu, Lynn W. Enquist and Esteban A. Engel 6 Alphaherpesvirus Latency and Reactivation with a Focus on Herpes Simplex Virus. 261 Nancy M. Sawtell and Richard L. Thompson 7 Host Innate Immune Response and Viral Immune Evasion During Alphaherpesvirus Infection.351 Krystal K. Lum and Ileana M. Cristea 8 Nuclear Egress. 403 Elizabeth B. Draganova, Michael K. Thorsen and Ekaterina E. Heldwein 9 Tegument Assembly, Secondary Envelopment andExocytosis. 449 Ian B. Hogue 10 Alphaherpesvirus Vaccines. 505 Clare Burn Aschner and Betsy C. Herold 11 Oncolytic HSV Vectors and Anti-Tumor
Immunity.545 Joseph C. Glorioso, Justus B. Cohen, William F. Goins, Bonnie Hall, Joseph W. Jackson, Gary Kohanbash, Nduka Amankulor, Balveen Kaur, Michael A. Caligiuri, E. Antonio Chiocca, Eric C. Holland and Christophe Quéva
Alphaherpesviruses encompass a broad group of pathogens including neuroinvasive viruses that establish lifelong infections in the peripheral nervous system of humans and many other vertebrates. One prominent example are herpes simplex viruses that infect most humans and can cause diseases ranging from painful skin ulcers to deadly encephalitis. For decades, researchers have been asking what makes these viruses neurotropic, how they establish a latent state, and why these typically benign infections can sometimes have severe or lethal outcomes. Since the last edition of this volume in 2011. our understanding of the alphaherpesviruses has significantly advanced creating the need for this new book that distils the most important new information to provide a timely overview. Chapters are written by well-respected researchers, each offering their perspectives on the current state of the field, using herpes simplex virus as the main focus. Topics covered include: genomics: entry into the cell: genome delivery from the cell periphery to the nucleus: the fate of the genome in the nucleus: infection of neurons: establishment of latency: host cellular responses to infection: viral immune evasion strategies: capsid egress from the nucleus: virion assembly in the cytoplasm: vaccines: oncolytic vectors. This book is essential reading for students, virologists, immunologists, medical and veterinary professionals and scientists working on neuroinvasive alphaherpesviruses. It is also a recommended reading for anyone with an interest in neurovirology and persistent viral infections. |
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| isbn | 9781913652555 |
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| physical | 632 Seiten Illustrationen, Diagramme |
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| publisher | Caister Academic Press |
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| spelling | Alphaherpesviruses molecular biology, host interactions and control editors: Ekaterina E. Heldwein, Gregory A. Smith [Norfolk?,] UK Caister Academic Press [2020] © 2020 632 Seiten Illustrationen, Diagramme txt rdacontent n rdamedia nc rdacarrier Heldwein, Ekaterina E. edt wpr aut Smith, Gregory A. edt wpr aut Erscheint auch als Online-Ausgabe 978-1-913652-56-2 Digitalisierung UB Regensburg - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=032443928&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Digitalisierung UB Regensburg - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=032443928&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Klappentext |
| spellingShingle | Heldwein, Ekaterina E. Smith, Gregory A. Alphaherpesviruses molecular biology, host interactions and control |
| title | Alphaherpesviruses molecular biology, host interactions and control |
| title_auth | Alphaherpesviruses molecular biology, host interactions and control |
| title_exact_search | Alphaherpesviruses molecular biology, host interactions and control |
| title_exact_search_txtP | Alphaherpesviruses molecular biology, host interactions and control |
| title_full | Alphaherpesviruses molecular biology, host interactions and control editors: Ekaterina E. Heldwein, Gregory A. Smith |
| title_fullStr | Alphaherpesviruses molecular biology, host interactions and control editors: Ekaterina E. Heldwein, Gregory A. Smith |
| title_full_unstemmed | Alphaherpesviruses molecular biology, host interactions and control editors: Ekaterina E. Heldwein, Gregory A. Smith |
| title_short | Alphaherpesviruses |
| title_sort | alphaherpesviruses molecular biology host interactions and control |
| title_sub | molecular biology, host interactions and control |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=032443928&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=032443928&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA |
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