Stem cell therapy for vascular diseases: state of the evidence and clinical applications
Vascular diseases are the leading cause of death worldwide. Distinguished clinical and surgical approaches have attempted to overcome its morbidity and mortality; still 17.9 million people die every year due to vascular affections. Stem cell therapy has emerged as a promising therapeutic strategy. S...
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| Format: | Elektronisch E-Book |
| Sprache: | English |
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Cham, Switzerland
Springer
[2021]
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| Online-Zugang: | TUM01 UBR01 Volltext |
| Zusammenfassung: | Vascular diseases are the leading cause of death worldwide. Distinguished clinical and surgical approaches have attempted to overcome its morbidity and mortality; still 17.9 million people die every year due to vascular affections. Stem cell therapy has emerged as a promising therapeutic strategy. Stem cells synthesize and secrete cytokines that promote cell recruitment, immunomodulation, extracellular matrix remodeling, angiogenesis, and neuroregeneration, all of which promote regeneration. Besides that, stem cells are also capable of differentiating in various cell types, being employed in tissue engineering. Preclinical and clinical investigations have reported efficacy of stem cell therapy for various vascular diseases. Even though results are encouraging, the studies demonstrate variation in stem cell type and origin, route and protocol for administration, and concomitant use of other treatment strategies, impairing easy interpretation of results and clinical application. The purpose of this book is to compile and comprise the current state of the evidence regarding stem cell therapy for each vascular disease, elucidating possible clinical applications. More than an objective guide for readers on the use of this novel treatment strategy, this publication will advocate for stem cell therapy use and development and will be of significant interest to physicians in a wide range of disciplines as well as researchers |
| Beschreibung: | 1. Introduction to Stem Cell Therapy and its Application in Vascular Diseases -- 2. Types And Origin of Stem Cells -- 3. Stem Cell Delivery Techniques for Stroke and Peripheral Artery Disease -- 4. The Ethical Challenges of Stem Cell Therapy in Vascular Disorders -- 5. Bone Marrow-Derived Cells: from the Laboratory to the Clinic -- 6. Angiogenesis: Perspectives From Therapeutic Angiogenesis -- 7. Stem Cell Therapy for Diabetic Foot Ulcers -- 8. Venous Foot and Leg Ulcers -- 9. Induced Pluripotent Stem Cell-Derived Vascular Smooth Muscle Cells for Vascular Regeneration -- 10. Mesenchymal Stem Cell and Hematopoietic Stem Cell Transplantation for Vasculitis -- 11. Mesenchymal Stem Cell and Endothelial Progenitor Cell Transplantation for Buerger's Disease -- 12. Changing the Course of Peripheral Arterial Disease Using Adult Stem Progenitor Cells -- 13. Stem Cell Delivery for the Treatment of Arteriovenous Fistula Failure -- 14. Stem Cell Therapy to Improve Acute Myocardial Infarction Remodeling -- 15. Stem Cell Therapy for Stroke -- 16. Use of Stem Cells in the Treatment of Erectile Dysfunction -- 17. Stem Cell Therapy for Ophthalmic Vascular Disease -- 18. Stem Cell Therapy Delivery in Liver Disease -- 19. Stem Cell Therapy for Lymphedema |
| Beschreibung: | 1 Online-Ressource (xii, 425 Seiten) Illustrationen, Diagramme |
| ISBN: | 9783030569549 |
| DOI: | 10.1007/978-3-030-56954-9 |
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| 500 | |a 1. Introduction to Stem Cell Therapy and its Application in Vascular Diseases -- 2. Types And Origin of Stem Cells -- 3. Stem Cell Delivery Techniques for Stroke and Peripheral Artery Disease -- 4. The Ethical Challenges of Stem Cell Therapy in Vascular Disorders -- 5. Bone Marrow-Derived Cells: from the Laboratory to the Clinic -- 6. Angiogenesis: Perspectives From Therapeutic Angiogenesis -- 7. Stem Cell Therapy for Diabetic Foot Ulcers -- 8. Venous Foot and Leg Ulcers -- 9. Induced Pluripotent Stem Cell-Derived Vascular Smooth Muscle Cells for Vascular Regeneration -- 10. Mesenchymal Stem Cell and Hematopoietic Stem Cell Transplantation for Vasculitis -- 11. Mesenchymal Stem Cell and Endothelial Progenitor Cell Transplantation for Buerger's Disease -- 12. Changing the Course of Peripheral Arterial Disease Using Adult Stem Progenitor Cells -- 13. Stem Cell Delivery for the Treatment of Arteriovenous Fistula Failure -- 14. Stem Cell Therapy to Improve Acute Myocardial Infarction Remodeling -- 15. Stem Cell Therapy for Stroke -- 16. Use of Stem Cells in the Treatment of Erectile Dysfunction -- 17. Stem Cell Therapy for Ophthalmic Vascular Disease -- 18. Stem Cell Therapy Delivery in Liver Disease -- 19. Stem Cell Therapy for Lymphedema | ||
| 520 | |a Vascular diseases are the leading cause of death worldwide. Distinguished clinical and surgical approaches have attempted to overcome its morbidity and mortality; still 17.9 million people die every year due to vascular affections. Stem cell therapy has emerged as a promising therapeutic strategy. Stem cells synthesize and secrete cytokines that promote cell recruitment, immunomodulation, extracellular matrix remodeling, angiogenesis, and neuroregeneration, all of which promote regeneration. Besides that, stem cells are also capable of differentiating in various cell types, being employed in tissue engineering. Preclinical and clinical investigations have reported efficacy of stem cell therapy for various vascular diseases. Even though results are encouraging, the studies demonstrate variation in stem cell type and origin, route and protocol for administration, and concomitant use of other treatment strategies, impairing easy interpretation of results and clinical application. The purpose of this book is to compile and comprise the current state of the evidence regarding stem cell therapy for each vascular disease, elucidating possible clinical applications. More than an objective guide for readers on the use of this novel treatment strategy, this publication will advocate for stem cell therapy use and development and will be of significant interest to physicians in a wide range of disciplines as well as researchers | ||
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Datensatz im Suchindex
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| isbn | 9783030569549 |
| language | English |
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| spelling | Stem cell therapy for vascular diseases state of the evidence and clinical applications Tulio Pinho Navarro, Lara Lellis Navarro Minchillo Lopes, Alan Dardik, editors Cham, Switzerland Springer [2021] 1 Online-Ressource (xii, 425 Seiten) Illustrationen, Diagramme txt rdacontent c rdamedia cr rdacarrier 1. Introduction to Stem Cell Therapy and its Application in Vascular Diseases -- 2. Types And Origin of Stem Cells -- 3. Stem Cell Delivery Techniques for Stroke and Peripheral Artery Disease -- 4. The Ethical Challenges of Stem Cell Therapy in Vascular Disorders -- 5. Bone Marrow-Derived Cells: from the Laboratory to the Clinic -- 6. Angiogenesis: Perspectives From Therapeutic Angiogenesis -- 7. Stem Cell Therapy for Diabetic Foot Ulcers -- 8. Venous Foot and Leg Ulcers -- 9. Induced Pluripotent Stem Cell-Derived Vascular Smooth Muscle Cells for Vascular Regeneration -- 10. Mesenchymal Stem Cell and Hematopoietic Stem Cell Transplantation for Vasculitis -- 11. Mesenchymal Stem Cell and Endothelial Progenitor Cell Transplantation for Buerger's Disease -- 12. Changing the Course of Peripheral Arterial Disease Using Adult Stem Progenitor Cells -- 13. Stem Cell Delivery for the Treatment of Arteriovenous Fistula Failure -- 14. Stem Cell Therapy to Improve Acute Myocardial Infarction Remodeling -- 15. Stem Cell Therapy for Stroke -- 16. Use of Stem Cells in the Treatment of Erectile Dysfunction -- 17. Stem Cell Therapy for Ophthalmic Vascular Disease -- 18. Stem Cell Therapy Delivery in Liver Disease -- 19. Stem Cell Therapy for Lymphedema Vascular diseases are the leading cause of death worldwide. Distinguished clinical and surgical approaches have attempted to overcome its morbidity and mortality; still 17.9 million people die every year due to vascular affections. Stem cell therapy has emerged as a promising therapeutic strategy. Stem cells synthesize and secrete cytokines that promote cell recruitment, immunomodulation, extracellular matrix remodeling, angiogenesis, and neuroregeneration, all of which promote regeneration. Besides that, stem cells are also capable of differentiating in various cell types, being employed in tissue engineering. Preclinical and clinical investigations have reported efficacy of stem cell therapy for various vascular diseases. Even though results are encouraging, the studies demonstrate variation in stem cell type and origin, route and protocol for administration, and concomitant use of other treatment strategies, impairing easy interpretation of results and clinical application. The purpose of this book is to compile and comprise the current state of the evidence regarding stem cell therapy for each vascular disease, elucidating possible clinical applications. More than an objective guide for readers on the use of this novel treatment strategy, this publication will advocate for stem cell therapy use and development and will be of significant interest to physicians in a wide range of disciplines as well as researchers Vascular surgery Cardiology Neurology Pinho Navarro, Tulio (DE-588)129317954X edt Lellis Navarro Minchillo Lopes, Lara (DE-588)129317999X edt Dardik, Alan edt Erscheint auch als Druck-Ausgabe 978-3-030-56953-2 Erscheint auch als Druck-Ausgabe 978-3-030-56955-6 Erscheint auch als Druck-Ausgabe 978-3-030-56956-3 https://doi.org/10.1007/978-3-030-56954-9 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Stem cell therapy for vascular diseases state of the evidence and clinical applications Vascular surgery Cardiology Neurology |
| title | Stem cell therapy for vascular diseases state of the evidence and clinical applications |
| title_auth | Stem cell therapy for vascular diseases state of the evidence and clinical applications |
| title_exact_search | Stem cell therapy for vascular diseases state of the evidence and clinical applications |
| title_exact_search_txtP | Stem cell therapy for vascular diseases state of the evidence and clinical applications |
| title_full | Stem cell therapy for vascular diseases state of the evidence and clinical applications Tulio Pinho Navarro, Lara Lellis Navarro Minchillo Lopes, Alan Dardik, editors |
| title_fullStr | Stem cell therapy for vascular diseases state of the evidence and clinical applications Tulio Pinho Navarro, Lara Lellis Navarro Minchillo Lopes, Alan Dardik, editors |
| title_full_unstemmed | Stem cell therapy for vascular diseases state of the evidence and clinical applications Tulio Pinho Navarro, Lara Lellis Navarro Minchillo Lopes, Alan Dardik, editors |
| title_short | Stem cell therapy for vascular diseases |
| title_sort | stem cell therapy for vascular diseases state of the evidence and clinical applications |
| title_sub | state of the evidence and clinical applications |
| topic | Vascular surgery Cardiology Neurology |
| topic_facet | Vascular surgery Cardiology Neurology |
| url | https://doi.org/10.1007/978-3-030-56954-9 |
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