Nanotechnology and microfluidics:
Gespeichert in:
| Weitere Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Weinheim
Wiley-VCH
[2020]
|
| Schriftenreihe: | Nanoscience and technology
|
| Schlagworte: | |
| Online-Zugang: | http://www.wiley-vch.de/publish/dt/books/ISBN978-3-527-34533-5/ Inhaltsverzeichnis |
| Beschreibung: | xiv, 429 Seiten Illustrationen, Diagramme 24.4 cm x 17 cm |
| ISBN: | 9783527345335 3527345337 |
Internformat
MARC
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| 003 | DE-604 | ||
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| 008 | 201007s2020 gw a||| |||| 00||| eng d | ||
| 015 | |a 19,N31 |2 dnb | ||
| 016 | 7 | |a 1191204502 |2 DE-101 | |
| 020 | |a 9783527345335 |c : circa EUR 149.00 (DE) (freier Preis) |9 978-3-527-34533-5 | ||
| 020 | |a 3527345337 |9 3-527-34533-7 | ||
| 024 | 3 | |a 9783527345335 | |
| 028 | 5 | 2 | |a Bestellnummer: 1134533 000 |
| 035 | |a (OCoLC)1157325455 | ||
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| 084 | |a UF 4500 |0 (DE-625)145585: |2 rvk | ||
| 084 | |a 540 |2 sdnb | ||
| 245 | 1 | 0 | |a Nanotechnology and microfluidics |c edited by Xingyu Jiang |
| 264 | 1 | |a Weinheim |b Wiley-VCH |c [2020] | |
| 300 | |a xiv, 429 Seiten |b Illustrationen, Diagramme |c 24.4 cm x 17 cm | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 490 | 0 | |a Nanoscience and technology | |
| 650 | 0 | 7 | |a Mikrofluidik |0 (DE-588)4803438-1 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Nanotechnologie |0 (DE-588)4327470-5 |2 gnd |9 rswk-swf |
| 653 | |a Hardback | ||
| 653 | |a Analytical Chemistry | ||
| 653 | |a Analytische Chemie | ||
| 653 | |a Chemie | ||
| 653 | |a Chemistry | ||
| 653 | |a Dünne Schichten, Oberflächen u. Grenzflächen | ||
| 653 | |a Materials Science | ||
| 653 | |a Materialwissenschaften | ||
| 653 | |a Mikrofluidik | ||
| 653 | |a Nanotechnologie | ||
| 653 | |a Pharmaceutical & Medicinal Chemistry | ||
| 653 | |a Pharmazeutische u. Medizinische Chemie | ||
| 653 | |a Thin Films, Surfaces & Interfaces | ||
| 653 | |a CH10: Analytische Chemie | ||
| 653 | |a CH60: Pharmazeutische u. Medizinische Chemie | ||
| 653 | |a MS80: Dünne Schichten, Oberflächen u. Grenzflächen | ||
| 653 | |a 1650: Hardcover, Softcover / Chemie | ||
| 655 | 7 | |0 (DE-588)4143413-4 |a Aufsatzsammlung |2 gnd-content | |
| 689 | 0 | 0 | |a Mikrofluidik |0 (DE-588)4803438-1 |D s |
| 689 | 0 | 1 | |a Nanotechnologie |0 (DE-588)4327470-5 |D s |
| 689 | 0 | |5 DE-604 | |
| 700 | 1 | |a Jiang, Xingyu |4 edt | |
| 710 | 2 | |a Wiley-VCH |0 (DE-588)16179388-5 |4 pbl | |
| 776 | 0 | 8 | |i Erscheint auch als |n Online-Ausgabe, PDF |z 978-3-527-81833-4 |
| 776 | 0 | 8 | |i Erscheint auch als |n Online-Ausgabe, EPUB |z 978-3-527-81835-8 |
| 776 | 0 | 8 | |i Erscheint auch als |n Online-Ausgabe |z 978-3-527-81834-1 |
| 856 | 4 | 2 | |m X:MVB |u http://www.wiley-vch.de/publish/dt/books/ISBN978-3-527-34533-5/ |
| 856 | 4 | 2 | |m DNB Datenaustausch |q application/pdf |u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=032338655&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |3 Inhaltsverzeichnis |
| 999 | |a oai:aleph.bib-bvb.de:BVB01-032338655 | ||
Datensatz im Suchindex
| _version_ | 1804181823461261312 |
|---|---|
| adam_text | CONTENTS
PREFACE
XIII
1
MICRO/NANOSTRUCTURED
MATERIALS
FROM
DROPLET
MICROFLUIDICS
1
XIN
ZHAO,
JIESHOU
LI,
AND
YUANJIN
ZHAO
1.1
INTRODUCTION
1
1.2
MMS
FROM
DROPLET
MICROFLUIDICS
4
1.2.1
SIMPLE
SPHERICAL
MICROPARTICLES
(MPS)
4
1.2.2
JANUS
MPS
7
1.2.3
CORE-SHELL
MPS
7
1.2.4
POROUS
MPS
9
1.2.5
OTHER
MMS
10
1.3
NMS
FROM
DROPLET
MICROFLUIDICS
13
1.3.1
INORGANIC
NMS
13
1.3.2
ORGANIC
NMS
16
1.3.3
OTHER
NMS
16
1.4
APPLICATIONS
OF
THE
DROPLET-DERIVED
MATERIALS
18
1.4.1
DRUG
DELIVERY
18
1.4.2
CELL
MICROENCAPSULATION
23
1.4.3
TISSUE
ENGINEERING
25
1.4.4
BIOSENSORS
29
1.4.5
BARCODES
32
1.5
CONCLUSION
AND
PERSPECTIVES
35
REFERENCES
36
2
DIGITAL
MICROFLUIDICS
FOR
BIOANALYSIS
47
QINGYU
RUAN,
JINGJING
GUO,
YANG
WANG,
FENXIANG
ZOU,
XIAOYE
LIN,
WEI
WANG,
AND
CHAOYONG
YANG
2.1
INTRODUCTION
47
2.2
THEORETICAL
BACKGROUND
48
2.2.1
THEORETICAL
BACKGROUND
48
2.2.1.1
THERMODYNAMIC
APPROACH
49
2.2.1.2
ENERGY
MINIMIZATION
APPROACH
50
2.2.1.3
ELECTROMECHANICAL
APPROACH
52
2.2.2
CONTACT
ANGLE
SATURATION
53
2.23
BASIC
MICROFLUIDIC
FUNCTIONS
BY
EWOD
ACTUATION
53
2.3
DEVICE
FABRICATION
55
VI
CONTENTS
2.4
2.4.1
2.4.1.1
2.4.1.2
2.4.1.3
2.4.2
2.4.2.1
2.4.2.2
2.4.2.3
2.5
2.5.1
2.5.2
2.5.3
2.5.4
2.6
DIGITAL
MICROFLUIDICS
INTEGRATED
WITH
OTHER
DEVICES
56
SAMPLE
PROCESSING
SYSTEMS
INTEGRATED
WITH
DIGITAL
MICROFLUIDICS
56
WORLD-TO-CHIP
INTERFACE
56
MAGNET
SEPARATION
58
HEATER
MODULE
59
DETECTION
SYSTEMS
INTEGRATED
WITH
DIGITAL
MICROFLUIDICS
59
OPTICAL
METHODS
59
ELECTROCHEMICAL
METHODS
61
OTHER
DETECTION
METHODS
62
BIOLOGICAL
APPLICATIONS
ON
DMF
63
ENZYME
ASSAYS
63
IMMUNOASSAY
63
DNA-BASED
APPLICATIONS
66
CELL-BASED
APPLICATIONS
68
CONCLUSIONS
AND
PERSPECTIVES
72
REFERENCES
73
3
NANOTECHNOLOGY
AND
MICROFLUIDICS
FOR
BIOSENSING
AND
BIOPHYSICAL
PROPERTY
ASSESSMENT:
IMPLICATIONS
FOR
NEXT-GENERATION
IN
VITRO
DIAGNOSTICS
83
ZIDA
LI
AND
HO
CHEUNG
SHUM
3.1
3.1.1
3.2
3.2.1
3.2.2
3.3
3.3.1
3.3.1.1
3.3.1.2
3.3.1.3
3.3.1.4
3.3.2
3.3.2.1
3.3.2.2
3.4
3.4.1
3.4.2
3.4.3
3.4.4
3.5
INTRODUCTION
83
NANOTECHNOLOGY
AND
MICROFLUIDICS
84
FUNDAMENTALS
OF
NANOTECHNOLOGY
AND
MICROFLUIDICS
86
NANOTECHNOLOGY
86
MICROFLUIDICS
87
BIOMOLECULE
SENSING
88
TECHNIQUES
BASED
ON
OPTICAL
READOUT
89
LOCALIZED
SURFACE
PLASMON
RESONANCE
89
SURFACE-ENHANCED
RAMAN
SPECTROSCOPY
90
NANOENGINEERED
FLUORESCENCE
PROBES
91
NANOTOPOGRAPHY-BASED
CELL
CAPTURING
93
TECHNIQUES
BASED
ON
ELECTRICAL
READOUTS
93
ELECTROCHEMICAL
REACTIONS
93
NANOTRANSISTOR-BASED
ASSAYS
94
BIOPHYSICAL
PROPERTY
SENSING
95
CELL
CONTRACTILITY
MEASUREMENT
96
CELL
DEFORMABILITY
98
FLUID
RHEOLOGY
99
ELECTROPHYSIOLOGY
99
CONCLUDING
REMARKS
100
ACKNOWLEDGMENTS
100
REFERENCES
101
4
MICROFLUIDIC
TOOLS
FOR
THE
SYNTHESIS
OF
BESPOKE
QUANTUM
DOTS
109
SHANGKUN
L/
Z
JEFFC.
HSIAO,
PHILIP
D.
HOWES,
AND
ANDREW
J.
DEMELLO
4.1
INTRODUCTION
109
CONTENTS
|
VII
4.1.1
MICROFLUIDICS
IN
THE
CHEMICAL
AND
BIOLOGICAL
SCIENCES
109
4.1.2
COMPOUND
SEMICONDUCTOR
NANOPARTICLES
109
4.1.3
MICROFLUIDIC
TOOLS
FOR
NANOPARTICLE
SYNTHESIS
112
4.2
DESIGN
CONSIDERATIONS
114
4.2.1
CONTINUOUS-FLOW
MICROFLUIDICS
115
4.2.2
SEGMENTED-FLOW
MICROFLUIDICS
115
4.3
CONTINUOUS-FLOW
MICROFLUIDIC
SYNTHESIS
OF
QUANTUM
DOTS
118
4.3.1
HOMOGENOUS
CORE-TYPE
QUANTUM
DOTS
IN
CONTINUOUS
FLOW
118
4.3.1.1
CADMIUM
SULFIDE
(CDS)
118
4.3.1.2
CADMIUM
SELENIDE
(CDSE)
119
4.3.2
HETEROGENOUS
CORE/SHELL
QUANTUM
DOTS
IN
CONTINUOUS
FLOW
121
4.3.2.1
ZINC
SELENIDE/ZINC
SULFIDE
(ZNSE/ZNS)
121
4.3.2.2
CADMIUM
SELENIDE/ZINC
SULFIDE
(CDSE/ZNS)
AND
CADMIUM
TELLURIDE/ZINC
SULFIDE
(CDTE/ZNS)
121
4.3.2.3
COPPER
INDIUM
SULFIDE/ZINC
SULFIDE
(CUINS
2
/ZNS)
123
4.3.2.4
INDIUM
PHOSPHIDE/ZINC
SULFIDE
(INP/ZNS)
125
4.3.3
HETEROGENOUS
CORE/MULTISHELL
QUANTUM
DOTS
IN
CONTINUOUS
FLOW
125
4.3.3.1
CADMIUM
SELENIDE/CADMIUM
SULFIDE/ZINC
SULFIDE
(CDSE/CDS/ZNS)
126
4.3.4
SUMMARY
OF
QD
CLASSES
128
4.4
SEGMENTED-FLOW
MICROFLUIDIC
SYNTHESIS
OF
QUANTUM
DOTS
128
4.4.1
HOMOGENOUS
STRUCTURE
QUANTUM
DOTS
IN
SEGMENTED
FLOW
129
4.4.1.1
CADMIUM
SULFIDE
(CDS)
129
4.4.1.2
CADMIUM
SELENIDE
(CDSE)
130
4.4.1.3
LEAD
SULFIDE
(PBS)
AND
LEAD
SELENIDE
(PBSE)
131
4.4.1.4
PEROVSKITE
QDS
132
4.4.2
HETEROGENOUS
CORE/SHELL
QUANTUM
DOTS
IN
SEGMENTED
FLOW
134
4.4.2.1
COPPER
INDIUM
SULFIDE/ZINC
SULFIDE
(CUINS
2
/ZNS)
134
4.4.3
MULTISTEP
SYNTHESIS
OF
QDS
IN
SEGMENTED
FLOW
135
4.4.4
NUCLEATION
AND
GROWTH
STUDIES
OF
QUANTUM
DOTS
138
4.5
CONCLUSIONS
AND
OUTLOOK
140
REFERENCES
141
5
MICROFLUIDICS
FOR
IMMUNO-ONCOLOGY
149
CHAO
MA,
JACOB
HARRIS,
RENEE-TYLER
T.
MORALES,
AND
WEIQLANG
CHEN
5.1
INTRODUCTION
149
5.2
MICROFLUIDICS
FOR
SINGLE
IMMUNE
CELL
ANALYSIS
153
5.2.1
SINGLE
IMMUNE
CELLS
153
5.2.1.1
T
CELLS
153
5.2.1.2
M DS
156
5.2.1.3
DCS
157
5.2.1.4
B
CELLS
158
5.2.2
MICROFLUIDICS
FOR
IMMUNE
AND
TUMOR
CELL
INTERACTION
ANALYSIS
159
5.2.2.1
T-CELL
PRIMING
AND
ACTIVATION
BY
APCS
159
5.2.2.2
KILLING
OF
CANCER
CELLS
BY
IMMUNE
EFFECTOR
CELLS
162
5.2.2.3
INTERACTION
BETWEEN
CANCER
CELLS
AND
MD S
163
5.3
MICROFLUIDICS
FOR
TUMOR
IMMUNE
MICROENVIRONMENT
ANALYSIS
163
VIII
CONTENTS
5.3.1
5.3.1.1
5.3.1.2
5.3.1.3
5.3.1.4
5.3.2
5.3.2.1
5.3.2.2
5.4
MODELING
THE
TUMOR
IMMUNE
MICROENVIRONMENT
163
T-CELL
TRAFFICKING
AND
MIGRATION
164
T-CELL
PRIMING
AND
ACTIVATION
BY
APCS
165
APC
PROCESSING
AND
PRESENTATION
OF
TAAS
165
INTERACTION
BETWEEN
CANCER
CELLS
AND
M BS
166
ON-CHIP
TESTING
OF
TUMOR
IMMUNOTHERAPY
166
TCR
T
CELLS
167
IMMUNE
CHECKPOINT
BLOCKADE
167
CONCLUDING
REMARKS
AND
FUTURE
PERSPECTIVES
170
ACKNOWLEDGMENTS
171
REFERENCES
172
6
PAPER
AND
PAPER
HYBRID
MICROFLUIDIC
DEVICES
FOR
POINT-OF-CARE
DETECTION
OF
INFECTIOUS
DISEASES
177
HAMED
TAVAKOLI,
WAN
ZHOU,
LEI
MA,
QUNQUN
GUO,
AND
XIUJUN
LI
6.1
6.2
6.2.1
6.2.1.1
6.2.1.2
6.2.1.3
6.2.1.4
6.2.2
6.3
INTRODUCTION
177
FABRICATION
OF
PAPER-BASED
MICROFLUIDIC
DEVICES
179
FABRICATION
TECHNIQUES
FOR
PAPER-BASED
MICROFLUIDIC
PLATFORMS
179
PHYSICAL
BLOCKING
OF
PORES
IN
PAPER
180
PHYSICAL
DEPOSITION OF
REAGENTS
ON
PAPER
SURFACE
181
CHEMICAL
MODIFICATION
182
OTHER
TECHNIQUES
183
FABRICATION
OF
PAPER
HYBRID
MICROFLUIDIC
DEVICES
183
APPLICATION
OF
PAPER
AND
PAPER
HYBRID
MICROFLUIDIC
DEVICES
FOR
INFECTIOUS
DISEASE
DIAGNOSIS
184
6.3.1
6.3.2
6.3.3
6.4
COLORIMETRIC
DETECTION
185
FLUORESCENCE
DETECTION
187
ELECTROCHEMICAL
DETECTION
191
INTEGRATION
OF
NANOSENSORS
ON
PAPER
AND
PAPER
HYBRID
MICROFLUIDIC
DEVICES
FOR
INFECTIOUS
DISEASE
DIAGNOSIS
193
6.4.1
6.4.2
6.4.3
6.5
CARBON-BASED
NANOSENSORS
195
GOLD-BASED
NANOSENSORS
198
OTHER
NANOSENSORS
200
SUMMARY
AND
OUTLOOK
202
ACKNOWLEDGMENT
202
REFERENCES
203
7
BIOLOGICAL
DIAGNOSIS
BASED
ON
MICROFLUIDICS
AND
NANOTECHNOLOGY
211
NAVID
KASHANINEJAD,
MOHAMMAD
YAGHOOBI,
MOHAMMAD
POURHASSAN-MOGHADDAM,
SAJAD
R.
BAZAZ,
DAYONGJIN,
AND
MAJID
E.
WARKIANI
7.1
7.2
INTRODUCTION
211
QUANTUM
DOT-BASED
MICROFLUIDIC
BIOSENSOR
FOR
BIOLOGICAL
DIAGNOSIS
212
7.2.1
7.3
QDOT-BASED
DISEASE
DIAGNOSIS
USING
MICROFLUIDICS
213
UPCONVERSION
NANOPARTICLES
279
CONTENTS
IX
7.4
7.5
7.6
7.6.1
7.6.2
7.6.2.1
7.6.2.2
7.6.3
FLUORESCENT
BIODOTS
221
DIGITAL
MICROFLUIDIC
SYSTEMS
FOR
DIAGNOSIS
DETECTION
223
PAPER-BASED
DIAGNOSTICS
226
STRUCTURE
AND
CHEMISTRY
OF
PAPER
226
APPLICATIONS
OF
PAPER-BASED
DEVICES
IN
THE
DIAGNOSTICS
227
LABELED
BIOSENSING
228
LABEL-FREE
BIOSENSING
228
INTEGRATION
OF
NANOPARTICLES
WITH
PAPER-BASED
MICROFLUIDIC
DEVICES
228
7.6.3.1
7.6.3.2
7.7
GOLD
NANOMATERIALS
228
FLUORESCENT
NANOMATERIALS
229
CONCLUSION
AND
FUTURE
PERSPECTIVE
231
CONFLICTS
OF
INTEREST
231
ACKNOWLEDGMENT
231
REFERENCES
232
8
RECENT
DEVELOPMENTS
IN
MICROFLUIDIC-BASED
POINT-OF-CARE
TESTING
(POCT)
DIAGNOSES
239
DONG
WANG,
HO
N.
CHAN,
ZEYU
LIU,
SEAN
MICHEAL,
LIJUN
LI,
DORSA
B.
BANIANI,
MING
J.
A.
TAN,
LU
HUANG,
JIANTAO
WANG,
AND
HONGKAI
WU
8.1
8.2
8.2.1
8.2.2
8.2.3
8.2.4
8.3
8.3.1
8.3.2
8.4
8.4.1
8.4.2
8.4.3
8.5
8.6
INTRODUCTION
239
CELL
240
BLOOD
CELL
COUNTING
240
CHARACTERIZATION
OF
CD64
EXPRESSION
241
ENUMERATION
OF
CD4+
T
LYMPHOCYTES
FOR
HIV
MONITORING
242
CIRCULATING
TUMOR
CELL
(CTC)
ISOLATION
AND
ANALYSIS
243
NUCLEIC
ACID
245
NONISOTHERMAL
AMPLIFICATION
245
ISOTHERMAL
AMPLIFICATION
246
PROTEIN
253
NOVEL
CHEMISTRY
AND
NANOMATERIALS
253
3D-PRINTED
MICROFLUIDIC
DEVICES
256
DIGITAL
AND
DROPLET
MICROFLUIDICS
259
METABOLITES
AND
SMALL
MOLECULES
262
CONCLUSION
AND
OUTLOOK
271
ACKNOWLEDGMENTS
271
REFERENCES
271
9
MICROFLUIDICS
IN
MICROBIOME
AND
CANCER
RESEARCH
281
BARATH
UDAYASURYAN,
DANIEL
J.
SLADE,
AND
SCOTTS.
VERBRIDGE
9.1
9.2
9.2.1
9.2.2
9.2.3
9.2.4
9.2.5
INTRODUCTION
281
WHAT
IS
THE
MICROBIOME?
282
COMPOSITION
AND
BIOGEOGRAPHY
282
THE
MICROBIOME
AND
CANCER
285
HELICOBACTER
PYLORI
AND
GASTRIC
CANCER
286
FUSOBACTERIUM
NUCLEATUM
AND
CRC
287
BACTERIAL
INVASION
288
CONTENTS
9.3
STUDYING
THE
MICROBIOME
289
9.3.1
2D
MODELS
291
9.3.2
3D
MODELS
291
9.3.3
ORGAN-ON-A-CHIP
AND
THE
APPLICATION
OF
MICROFLUIDICS
295
9.4
MICROFLUIDIC
INTESTINE
CHIP
MODELS
297
9.4.1
GUT-ON-A-CHIP
MODEL
297
9.4.2
CO-CULTURE
OF
THE
GUT-ON-A-CHIP
WITH
MICROBIOTA
298
9.4.3
THE
HUMIX
MODEL
299
9.4.4
ANAEROBIC
HUMAN
INTESTINE
CHIP
301
9.4.5
ANOXIC-OXIC
INTERFACE
(AOI)-ON-A-CHIP
303
9.4.6
FUTURE
DIRECTIONS
304
9.5
CONCLUDING
REMARKS
AND
FUTURE
PERSPECTIVES
306
ACKNOWLEDGMENTS
308
REFERENCES
308
10
MICROFLUIDIC
SYNTHESIS
OF
FUNCTIONAL
NANOPARTICLES
319
ZIWEI
HAN
AND
XINGYU
JIANG
10.1
INTRODUCTION
319
10.2
FABRICATION
OF
MICROFLUIDIC
CHIPS
320
10.2.1
FABRICATION
OF
MICROCHANNELS:
PHOTOLITHOGRAPHY
321
10.2.2
FABRICATION
OF
PDMS-BASED
MICROFLUIDIC
CHIPS
321
10.2.3
PRESSURE
TOLERANCE
321
10.3
MICROFLUIDIC
SYNTHESIS
OF
FUNCTIONAL
NANOPARTICLES
323
10.3.1
MIXING
STRATEGY
323
10.3.1.1
HYDRODYNAMIC
FOCUSING
323
10.3.1.2
MICROSTRUCTURE
TO
ENHANCE
MIXING
EFFICIENCY
324
10.3.2
BIONANOPARTICLE
INTERACTIONS
325
10.3.2.1
WELL-CONTROLLED
SIZE
AND MONODISPERSITY
325
10.3.2.2
SURFACE
MODIFICATION
326
10.3.2.3
MECHANICAL
PROPERTIES
327
10.3.2.4
CONTROLLABLE
MULTILAYER
STRUCTURE
328
10.4
MICROFLUIDIC
ASSEMBLY
OF
NANOPARTICLES
FOR
BIOLOGICAL
AND
MEDICAL
APPLICATIONS
329
10.4.1
DRUG
DELIVERY
330
10.4.1.1
PH-SENSITIVE
DRUG
RELEASE
330
10.4.1.2
HYDROPHILIC
DRUG
DELIVERY
331
10.4.1.3
PHOTO
RESPONSIVE
DRUG
RELEASE
332
10.4.1.4
GENE
DELIVERY
332
10.4.2
IMAGING
332
10.4.2.1
MRI
332
10.4.2.2
FLUORESCENCE
IMAGING
333
10.4.2.3
ULTRASONIC
IMAGING
334
10.4.3
BIOSENSING
334
10.4.4
THERANOSTICS
336
10.5
PROSPECTS
OF
MICROFLUIDIC
SYNTHESIS
337
ACKNOWLEDGMENT
338
REFERENCES
339
CONTENTS
XI
11
DESIGN
CONSIDERATIONS
FOR
MUSCLE-ACTUATED
BIOHYBRID
DEVICES
347
YOSHITAKE
AKIYAMA,
SUNG-JIN
PARK,
AND
SHUICHI
TAKAYAMA
11.1
INTRODUCTION
347
11.2
CHARACTERISTICS
AND
APPLICABILITY
OF
MUSCLES
FOR
BIOHYBRID
DEVICES
348
11.2.1
HEART
MUSCLE
(CARDIOMYOCYTES)
348
11.2.2
SKELETAL
MUSCLE
CELLS
350
11.2.3
SMOOTH
MUSCLE
CELLS
351
11.2.4
NONMAMMALIAN
MUSCLE
CELLS
352
11.3
ARRANGEMENT
OF
MUSCLE
CELLS
AND
TISSUES
ON
BIOHYBRID
DEVICES
352
11.3.1
INTERFACES
BETWEEN
MUSCLE
CELLS
AND
MATERIAL
353
11.3.1.1
INTERFACES
IN
2D
CULTURE
353
11.3.1.2
INTERFACES
IN
3D
CULTURE
354
11.3.2
MECHANICAL
PAIRING
OF
MUSCLES
355
11.3.3
INTERFACE
BETWEEN
MEDIUM
AND
AIR
356
11.4
OXYGEN
SUPPLY
IN
MUSCLE
TISSUE
ENGINEERING
356
11.4.1
EQUATION
AND CONDITIONS
FOR
NUMERICAL
SIMULATIONS
357
11.4.2
OXYGEN
DISTRIBUTION
UNDER
STATIC
CULTURE
357
11.4.3
OXYGEN
DISTRIBUTION
IN
MICROFLUIDIC
DEVICES
359
11.4.4
OTHER
APPROACHES
TO
IMPROVE
OXYGEN
SUPPLY
360
11.5
CONTRACTILE
FORCE
OF
MUSCLE
BUNDLES
AND
STIMULATIONS
361
11.5.1
TISSUE-ENGINEERED
MUSCLE
CONSISTING
OF
C2C12
CELLS
361
11.5.2
TISSUE-ENGINEERED
MUSCLE
CONSISTING
OF
PRIMARY
MYOBLASTS
364
11.6
CONTROL
OF
MUSCLE
CONTRACTIONS
366
11.6.1
ELECTRICAL
STIMULATION
366
11.6.2
OPTICAL
STIMULATION
367
11.6.3
OTHERS
368
11.7
CONCLUSIONS
AND
FUTURE
CHALLENGES
368
11.7.1
COMPLETELY
3D-PRINTED
BIOHYBRID
DEVICES
368
11.7.2
INTEGRATION
WITH
OTHER
TISSUES
369
11.7.3
LONG-TERM
MAINTENANCE AND
SELF-HEALING
369
11.7.4
EXPLORING
APPLICATIONS
370
ACKNOWLEDGMENTS
370
REFERENCES
370
12
MICRO-
AND
NANOSCALE
BIOINTERROGATION
AND
MODULATION
OF
NEURAL
TISSUE
-
FROM
FUNDAMENTAL
TO
CLINICAL
AND
MILITARY
APPLICATIONS
383
JORDAN
MOORE,
DIEGO
ALZATE-CORREA,
DEVLEENA
DASGUPTA,
WILLIAM
LAWRENCE,
DANIEL
DODD,
CRAIG
MATHEWS,
IAN
VALERIO,
CAMERON
RINK,
NATALIA
HIGUITA-CASTRO,
AND
DANIEL
GALLEGO-PEREZ
12.1
INTRODUCTION
383
12.2
GENERAL
PRINCIPLES 385
12.2.1
PHYSICS
OF
MINIATURIZED
SYSTEMS
385
12.2.2
MATERIAL
PROPERTIES
385
12.3
AREAS
OF
STUDY
386
XII
CONTENTS
12.3.1
NEURODEVELOPMENT
386
12.3.2
NEURO-ONCOLOGY
388
12.3.3
NEURODEGENERATIVE
DISORDERS
389
12.3.4
TRAUMATIC
BRAIN
INJURY
392
12.4
APPLICATIONS
394
12.4.1
NEURON-DIRECTED
CELLULAR
REPROGRAMMING
394
12.4.2
TISSUE
NANOTRANSFECTION
396
12.4.3
CANCER
INTERROGATION
398
12.4.4
FISH
ON-CHIP
FOR
ALZHEIMER
*
S
DISEASE
401
12.4.5
ON-CHIP
BRAIN
INJURY
403
12.4.6
MILITARY
405
12.5
LIMITATIONS
AND
FUTURE
OUTLOOK
406
12.6
SUMMARY
407
REFERENCES
408
INDEX
419
|
| adam_txt |
CONTENTS
PREFACE
XIII
1
MICRO/NANOSTRUCTURED
MATERIALS
FROM
DROPLET
MICROFLUIDICS
1
XIN
ZHAO,
JIESHOU
LI,
AND
YUANJIN
ZHAO
1.1
INTRODUCTION
1
1.2
MMS
FROM
DROPLET
MICROFLUIDICS
4
1.2.1
SIMPLE
SPHERICAL
MICROPARTICLES
(MPS)
4
1.2.2
JANUS
MPS
7
1.2.3
CORE-SHELL
MPS
7
1.2.4
POROUS
MPS
9
1.2.5
OTHER
MMS
10
1.3
NMS
FROM
DROPLET
MICROFLUIDICS
13
1.3.1
INORGANIC
NMS
13
1.3.2
ORGANIC
NMS
16
1.3.3
OTHER
NMS
16
1.4
APPLICATIONS
OF
THE
DROPLET-DERIVED
MATERIALS
18
1.4.1
DRUG
DELIVERY
18
1.4.2
CELL
MICROENCAPSULATION
23
1.4.3
TISSUE
ENGINEERING
25
1.4.4
BIOSENSORS
29
1.4.5
BARCODES
32
1.5
CONCLUSION
AND
PERSPECTIVES
35
REFERENCES
36
2
DIGITAL
MICROFLUIDICS
FOR
BIOANALYSIS
47
QINGYU
RUAN,
JINGJING
GUO,
YANG
WANG,
FENXIANG
ZOU,
XIAOYE
LIN,
WEI
WANG,
AND
CHAOYONG
YANG
2.1
INTRODUCTION
47
2.2
THEORETICAL
BACKGROUND
48
2.2.1
THEORETICAL
BACKGROUND
48
2.2.1.1
THERMODYNAMIC
APPROACH
49
2.2.1.2
ENERGY
MINIMIZATION
APPROACH
50
2.2.1.3
ELECTROMECHANICAL
APPROACH
52
2.2.2
CONTACT
ANGLE
SATURATION
53
2.23
BASIC
MICROFLUIDIC
FUNCTIONS
BY
EWOD
ACTUATION
53
2.3
DEVICE
FABRICATION
55
VI
CONTENTS
2.4
2.4.1
2.4.1.1
2.4.1.2
2.4.1.3
2.4.2
2.4.2.1
2.4.2.2
2.4.2.3
2.5
2.5.1
2.5.2
2.5.3
2.5.4
2.6
DIGITAL
MICROFLUIDICS
INTEGRATED
WITH
OTHER
DEVICES
56
SAMPLE
PROCESSING
SYSTEMS
INTEGRATED
WITH
DIGITAL
MICROFLUIDICS
56
WORLD-TO-CHIP
INTERFACE
56
MAGNET
SEPARATION
58
HEATER
MODULE
59
DETECTION
SYSTEMS
INTEGRATED
WITH
DIGITAL
MICROFLUIDICS
59
OPTICAL
METHODS
59
ELECTROCHEMICAL
METHODS
61
OTHER
DETECTION
METHODS
62
BIOLOGICAL
APPLICATIONS
ON
DMF
63
ENZYME
ASSAYS
63
IMMUNOASSAY
63
DNA-BASED
APPLICATIONS
66
CELL-BASED
APPLICATIONS
68
CONCLUSIONS
AND
PERSPECTIVES
72
REFERENCES
73
3
NANOTECHNOLOGY
AND
MICROFLUIDICS
FOR
BIOSENSING
AND
BIOPHYSICAL
PROPERTY
ASSESSMENT:
IMPLICATIONS
FOR
NEXT-GENERATION
IN
VITRO
DIAGNOSTICS
83
ZIDA
LI
AND
HO
CHEUNG
SHUM
3.1
3.1.1
3.2
3.2.1
3.2.2
3.3
3.3.1
3.3.1.1
3.3.1.2
3.3.1.3
3.3.1.4
3.3.2
3.3.2.1
3.3.2.2
3.4
3.4.1
3.4.2
3.4.3
3.4.4
3.5
INTRODUCTION
83
NANOTECHNOLOGY
AND
MICROFLUIDICS
84
FUNDAMENTALS
OF
NANOTECHNOLOGY
AND
MICROFLUIDICS
86
NANOTECHNOLOGY
86
MICROFLUIDICS
87
BIOMOLECULE
SENSING
88
TECHNIQUES
BASED
ON
OPTICAL
READOUT
89
LOCALIZED
SURFACE
PLASMON
RESONANCE
89
SURFACE-ENHANCED
RAMAN
SPECTROSCOPY
90
NANOENGINEERED
FLUORESCENCE
PROBES
91
NANOTOPOGRAPHY-BASED
CELL
CAPTURING
93
TECHNIQUES
BASED
ON
ELECTRICAL
READOUTS
93
ELECTROCHEMICAL
REACTIONS
93
NANOTRANSISTOR-BASED
ASSAYS
94
BIOPHYSICAL
PROPERTY
SENSING
95
CELL
CONTRACTILITY
MEASUREMENT
96
CELL
DEFORMABILITY
98
FLUID
RHEOLOGY
99
ELECTROPHYSIOLOGY
99
CONCLUDING
REMARKS
100
ACKNOWLEDGMENTS
100
REFERENCES
101
4
MICROFLUIDIC
TOOLS
FOR
THE
SYNTHESIS
OF
BESPOKE
QUANTUM
DOTS
109
SHANGKUN
L/
Z
JEFFC.
HSIAO,
PHILIP
D.
HOWES,
AND
ANDREW
J.
DEMELLO
4.1
INTRODUCTION
109
CONTENTS
|
VII
4.1.1
MICROFLUIDICS
IN
THE
CHEMICAL
AND
BIOLOGICAL
SCIENCES
109
4.1.2
COMPOUND
SEMICONDUCTOR
NANOPARTICLES
109
4.1.3
MICROFLUIDIC
TOOLS
FOR
NANOPARTICLE
SYNTHESIS
112
4.2
DESIGN
CONSIDERATIONS
114
4.2.1
CONTINUOUS-FLOW
MICROFLUIDICS
115
4.2.2
SEGMENTED-FLOW
MICROFLUIDICS
115
4.3
CONTINUOUS-FLOW
MICROFLUIDIC
SYNTHESIS
OF
QUANTUM
DOTS
118
4.3.1
HOMOGENOUS
CORE-TYPE
QUANTUM
DOTS
IN
CONTINUOUS
FLOW
118
4.3.1.1
CADMIUM
SULFIDE
(CDS)
118
4.3.1.2
CADMIUM
SELENIDE
(CDSE)
119
4.3.2
HETEROGENOUS
CORE/SHELL
QUANTUM
DOTS
IN
CONTINUOUS
FLOW
121
4.3.2.1
ZINC
SELENIDE/ZINC
SULFIDE
(ZNSE/ZNS)
121
4.3.2.2
CADMIUM
SELENIDE/ZINC
SULFIDE
(CDSE/ZNS)
AND
CADMIUM
TELLURIDE/ZINC
SULFIDE
(CDTE/ZNS)
121
4.3.2.3
COPPER
INDIUM
SULFIDE/ZINC
SULFIDE
(CUINS
2
/ZNS)
123
4.3.2.4
INDIUM
PHOSPHIDE/ZINC
SULFIDE
(INP/ZNS)
125
4.3.3
HETEROGENOUS
CORE/MULTISHELL
QUANTUM
DOTS
IN
CONTINUOUS
FLOW
125
4.3.3.1
CADMIUM
SELENIDE/CADMIUM
SULFIDE/ZINC
SULFIDE
(CDSE/CDS/ZNS)
126
4.3.4
SUMMARY
OF
QD
CLASSES
128
4.4
SEGMENTED-FLOW
MICROFLUIDIC
SYNTHESIS
OF
QUANTUM
DOTS
128
4.4.1
HOMOGENOUS
STRUCTURE
QUANTUM
DOTS
IN
SEGMENTED
FLOW
129
4.4.1.1
CADMIUM
SULFIDE
(CDS)
129
4.4.1.2
CADMIUM
SELENIDE
(CDSE)
130
4.4.1.3
LEAD
SULFIDE
(PBS)
AND
LEAD
SELENIDE
(PBSE)
131
4.4.1.4
PEROVSKITE
QDS
132
4.4.2
HETEROGENOUS
CORE/SHELL
QUANTUM
DOTS
IN
SEGMENTED
FLOW
134
4.4.2.1
COPPER
INDIUM
SULFIDE/ZINC
SULFIDE
(CUINS
2
/ZNS)
134
4.4.3
MULTISTEP
SYNTHESIS
OF
QDS
IN
SEGMENTED
FLOW
135
4.4.4
NUCLEATION
AND
GROWTH
STUDIES
OF
QUANTUM
DOTS
138
4.5
CONCLUSIONS
AND
OUTLOOK
140
REFERENCES
141
5
MICROFLUIDICS
FOR
IMMUNO-ONCOLOGY
149
CHAO
MA,
JACOB
HARRIS,
RENEE-TYLER
T.
MORALES,
AND
WEIQLANG
CHEN
5.1
INTRODUCTION
149
5.2
MICROFLUIDICS
FOR
SINGLE
IMMUNE
CELL
ANALYSIS
153
5.2.1
SINGLE
IMMUNE
CELLS
153
5.2.1.1
T
CELLS
153
5.2.1.2
M DS
156
5.2.1.3
DCS
157
5.2.1.4
B
CELLS
158
5.2.2
MICROFLUIDICS
FOR
IMMUNE
AND
TUMOR
CELL
INTERACTION
ANALYSIS
159
5.2.2.1
T-CELL
PRIMING
AND
ACTIVATION
BY
APCS
159
5.2.2.2
KILLING
OF
CANCER
CELLS
BY
IMMUNE
EFFECTOR
CELLS
162
5.2.2.3
INTERACTION
BETWEEN
CANCER
CELLS
AND
MD S
163
5.3
MICROFLUIDICS
FOR
TUMOR
IMMUNE
MICROENVIRONMENT
ANALYSIS
163
VIII
CONTENTS
5.3.1
5.3.1.1
5.3.1.2
5.3.1.3
5.3.1.4
5.3.2
5.3.2.1
5.3.2.2
5.4
MODELING
THE
TUMOR
IMMUNE
MICROENVIRONMENT
163
T-CELL
TRAFFICKING
AND
MIGRATION
164
T-CELL
PRIMING
AND
ACTIVATION
BY
APCS
165
APC
PROCESSING
AND
PRESENTATION
OF
TAAS
165
INTERACTION
BETWEEN
CANCER
CELLS
AND
M BS
166
ON-CHIP
TESTING
OF
TUMOR
IMMUNOTHERAPY
166
TCR
T
CELLS
167
IMMUNE
CHECKPOINT
BLOCKADE
167
CONCLUDING
REMARKS
AND
FUTURE
PERSPECTIVES
170
ACKNOWLEDGMENTS
171
REFERENCES
172
6
PAPER
AND
PAPER
HYBRID
MICROFLUIDIC
DEVICES
FOR
POINT-OF-CARE
DETECTION
OF
INFECTIOUS
DISEASES
177
HAMED
TAVAKOLI,
WAN
ZHOU,
LEI
MA,
QUNQUN
GUO,
AND
XIUJUN
LI
6.1
6.2
6.2.1
6.2.1.1
6.2.1.2
6.2.1.3
6.2.1.4
6.2.2
6.3
INTRODUCTION
177
FABRICATION
OF
PAPER-BASED
MICROFLUIDIC
DEVICES
179
FABRICATION
TECHNIQUES
FOR
PAPER-BASED
MICROFLUIDIC
PLATFORMS
179
PHYSICAL
BLOCKING
OF
PORES
IN
PAPER
180
PHYSICAL
DEPOSITION OF
REAGENTS
ON
PAPER
SURFACE
181
CHEMICAL
MODIFICATION
182
OTHER
TECHNIQUES
183
FABRICATION
OF
PAPER
HYBRID
MICROFLUIDIC
DEVICES
183
APPLICATION
OF
PAPER
AND
PAPER
HYBRID
MICROFLUIDIC
DEVICES
FOR
INFECTIOUS
DISEASE
DIAGNOSIS
184
6.3.1
6.3.2
6.3.3
6.4
COLORIMETRIC
DETECTION
185
FLUORESCENCE
DETECTION
187
ELECTROCHEMICAL
DETECTION
191
INTEGRATION
OF
NANOSENSORS
ON
PAPER
AND
PAPER
HYBRID
MICROFLUIDIC
DEVICES
FOR
INFECTIOUS
DISEASE
DIAGNOSIS
193
6.4.1
6.4.2
6.4.3
6.5
CARBON-BASED
NANOSENSORS
195
GOLD-BASED
NANOSENSORS
198
OTHER
NANOSENSORS
200
SUMMARY
AND
OUTLOOK
202
ACKNOWLEDGMENT
202
REFERENCES
203
7
BIOLOGICAL
DIAGNOSIS
BASED
ON
MICROFLUIDICS
AND
NANOTECHNOLOGY
211
NAVID
KASHANINEJAD,
MOHAMMAD
YAGHOOBI,
MOHAMMAD
POURHASSAN-MOGHADDAM,
SAJAD
R.
BAZAZ,
DAYONGJIN,
AND
MAJID
E.
WARKIANI
7.1
7.2
INTRODUCTION
211
QUANTUM
DOT-BASED
MICROFLUIDIC
BIOSENSOR
FOR
BIOLOGICAL
DIAGNOSIS
212
7.2.1
7.3
QDOT-BASED
DISEASE
DIAGNOSIS
USING
MICROFLUIDICS
213
UPCONVERSION
NANOPARTICLES
279
CONTENTS
IX
7.4
7.5
7.6
7.6.1
7.6.2
7.6.2.1
7.6.2.2
7.6.3
FLUORESCENT
BIODOTS
221
DIGITAL
MICROFLUIDIC
SYSTEMS
FOR
DIAGNOSIS
DETECTION
223
PAPER-BASED
DIAGNOSTICS
226
STRUCTURE
AND
CHEMISTRY
OF
PAPER
226
APPLICATIONS
OF
PAPER-BASED
DEVICES
IN
THE
DIAGNOSTICS
227
LABELED
BIOSENSING
228
LABEL-FREE
BIOSENSING
228
INTEGRATION
OF
NANOPARTICLES
WITH
PAPER-BASED
MICROFLUIDIC
DEVICES
228
7.6.3.1
7.6.3.2
7.7
GOLD
NANOMATERIALS
228
FLUORESCENT
NANOMATERIALS
229
CONCLUSION
AND
FUTURE
PERSPECTIVE
231
CONFLICTS
OF
INTEREST
231
ACKNOWLEDGMENT
231
REFERENCES
232
8
RECENT
DEVELOPMENTS
IN
MICROFLUIDIC-BASED
POINT-OF-CARE
TESTING
(POCT)
DIAGNOSES
239
DONG
WANG,
HO
N.
CHAN,
ZEYU
LIU,
SEAN
MICHEAL,
LIJUN
LI,
DORSA
B.
BANIANI,
MING
J.
A.
TAN,
LU
HUANG,
JIANTAO
WANG,
AND
HONGKAI
WU
8.1
8.2
8.2.1
8.2.2
8.2.3
8.2.4
8.3
8.3.1
8.3.2
8.4
8.4.1
8.4.2
8.4.3
8.5
8.6
INTRODUCTION
239
CELL
240
BLOOD
CELL
COUNTING
240
CHARACTERIZATION
OF
CD64
EXPRESSION
241
ENUMERATION
OF
CD4+
T
LYMPHOCYTES
FOR
HIV
MONITORING
242
CIRCULATING
TUMOR
CELL
(CTC)
ISOLATION
AND
ANALYSIS
243
NUCLEIC
ACID
245
NONISOTHERMAL
AMPLIFICATION
245
ISOTHERMAL
AMPLIFICATION
246
PROTEIN
253
NOVEL
CHEMISTRY
AND
NANOMATERIALS
253
3D-PRINTED
MICROFLUIDIC
DEVICES
256
DIGITAL
AND
DROPLET
MICROFLUIDICS
259
METABOLITES
AND
SMALL
MOLECULES
262
CONCLUSION
AND
OUTLOOK
271
ACKNOWLEDGMENTS
271
REFERENCES
271
9
MICROFLUIDICS
IN
MICROBIOME
AND
CANCER
RESEARCH
281
BARATH
UDAYASURYAN,
DANIEL
J.
SLADE,
AND
SCOTTS.
VERBRIDGE
9.1
9.2
9.2.1
9.2.2
9.2.3
9.2.4
9.2.5
INTRODUCTION
281
WHAT
IS
THE
MICROBIOME?
282
COMPOSITION
AND
BIOGEOGRAPHY
282
THE
MICROBIOME
AND
CANCER
285
HELICOBACTER
PYLORI
AND
GASTRIC
CANCER
286
FUSOBACTERIUM
NUCLEATUM
AND
CRC
287
BACTERIAL
INVASION
288
CONTENTS
9.3
STUDYING
THE
MICROBIOME
289
9.3.1
2D
MODELS
291
9.3.2
3D
MODELS
291
9.3.3
ORGAN-ON-A-CHIP
AND
THE
APPLICATION
OF
MICROFLUIDICS
295
9.4
MICROFLUIDIC
INTESTINE
CHIP
MODELS
297
9.4.1
GUT-ON-A-CHIP
MODEL
297
9.4.2
CO-CULTURE
OF
THE
GUT-ON-A-CHIP
WITH
MICROBIOTA
298
9.4.3
THE
HUMIX
MODEL
299
9.4.4
ANAEROBIC
HUMAN
INTESTINE
CHIP
301
9.4.5
ANOXIC-OXIC
INTERFACE
(AOI)-ON-A-CHIP
303
9.4.6
FUTURE
DIRECTIONS
304
9.5
CONCLUDING
REMARKS
AND
FUTURE
PERSPECTIVES
306
ACKNOWLEDGMENTS
308
REFERENCES
308
10
MICROFLUIDIC
SYNTHESIS
OF
FUNCTIONAL
NANOPARTICLES
319
ZIWEI
HAN
AND
XINGYU
JIANG
10.1
INTRODUCTION
319
10.2
FABRICATION
OF
MICROFLUIDIC
CHIPS
320
10.2.1
FABRICATION
OF
MICROCHANNELS:
PHOTOLITHOGRAPHY
321
10.2.2
FABRICATION
OF
PDMS-BASED
MICROFLUIDIC
CHIPS
321
10.2.3
PRESSURE
TOLERANCE
321
10.3
MICROFLUIDIC
SYNTHESIS
OF
FUNCTIONAL
NANOPARTICLES
323
10.3.1
MIXING
STRATEGY
323
10.3.1.1
HYDRODYNAMIC
FOCUSING
323
10.3.1.2
MICROSTRUCTURE
TO
ENHANCE
MIXING
EFFICIENCY
324
10.3.2
BIONANOPARTICLE
INTERACTIONS
325
10.3.2.1
WELL-CONTROLLED
SIZE
AND MONODISPERSITY
325
10.3.2.2
SURFACE
MODIFICATION
326
10.3.2.3
MECHANICAL
PROPERTIES
327
10.3.2.4
CONTROLLABLE
MULTILAYER
STRUCTURE
328
10.4
MICROFLUIDIC
ASSEMBLY
OF
NANOPARTICLES
FOR
BIOLOGICAL
AND
MEDICAL
APPLICATIONS
329
10.4.1
DRUG
DELIVERY
330
10.4.1.1
PH-SENSITIVE
DRUG
RELEASE
330
10.4.1.2
HYDROPHILIC
DRUG
DELIVERY
331
10.4.1.3
PHOTO
RESPONSIVE
DRUG
RELEASE
332
10.4.1.4
GENE
DELIVERY
332
10.4.2
IMAGING
332
10.4.2.1
MRI
332
10.4.2.2
FLUORESCENCE
IMAGING
333
10.4.2.3
ULTRASONIC
IMAGING
334
10.4.3
BIOSENSING
334
10.4.4
THERANOSTICS
336
10.5
PROSPECTS
OF
MICROFLUIDIC
SYNTHESIS
337
ACKNOWLEDGMENT
338
REFERENCES
339
CONTENTS
XI
11
DESIGN
CONSIDERATIONS
FOR
MUSCLE-ACTUATED
BIOHYBRID
DEVICES
347
YOSHITAKE
AKIYAMA,
SUNG-JIN
PARK,
AND
SHUICHI
TAKAYAMA
11.1
INTRODUCTION
347
11.2
CHARACTERISTICS
AND
APPLICABILITY
OF
MUSCLES
FOR
BIOHYBRID
DEVICES
348
11.2.1
HEART
MUSCLE
(CARDIOMYOCYTES)
348
11.2.2
SKELETAL
MUSCLE
CELLS
350
11.2.3
SMOOTH
MUSCLE
CELLS
351
11.2.4
NONMAMMALIAN
MUSCLE
CELLS
352
11.3
ARRANGEMENT
OF
MUSCLE
CELLS
AND
TISSUES
ON
BIOHYBRID
DEVICES
352
11.3.1
INTERFACES
BETWEEN
MUSCLE
CELLS
AND
MATERIAL
353
11.3.1.1
INTERFACES
IN
2D
CULTURE
353
11.3.1.2
INTERFACES
IN
3D
CULTURE
354
11.3.2
MECHANICAL
PAIRING
OF
MUSCLES
355
11.3.3
INTERFACE
BETWEEN
MEDIUM
AND
AIR
356
11.4
OXYGEN
SUPPLY
IN
MUSCLE
TISSUE
ENGINEERING
356
11.4.1
EQUATION
AND CONDITIONS
FOR
NUMERICAL
SIMULATIONS
357
11.4.2
OXYGEN
DISTRIBUTION
UNDER
STATIC
CULTURE
357
11.4.3
OXYGEN
DISTRIBUTION
IN
MICROFLUIDIC
DEVICES
359
11.4.4
OTHER
APPROACHES
TO
IMPROVE
OXYGEN
SUPPLY
360
11.5
CONTRACTILE
FORCE
OF
MUSCLE
BUNDLES
AND
STIMULATIONS
361
11.5.1
TISSUE-ENGINEERED
MUSCLE
CONSISTING
OF
C2C12
CELLS
361
11.5.2
TISSUE-ENGINEERED
MUSCLE
CONSISTING
OF
PRIMARY
MYOBLASTS
364
11.6
CONTROL
OF
MUSCLE
CONTRACTIONS
366
11.6.1
ELECTRICAL
STIMULATION
366
11.6.2
OPTICAL
STIMULATION
367
11.6.3
OTHERS
368
11.7
CONCLUSIONS
AND
FUTURE
CHALLENGES
368
11.7.1
COMPLETELY
3D-PRINTED
BIOHYBRID
DEVICES
368
11.7.2
INTEGRATION
WITH
OTHER
TISSUES
369
11.7.3
LONG-TERM
MAINTENANCE AND
SELF-HEALING
369
11.7.4
EXPLORING
APPLICATIONS
370
ACKNOWLEDGMENTS
370
REFERENCES
370
12
MICRO-
AND
NANOSCALE
BIOINTERROGATION
AND
MODULATION
OF
NEURAL
TISSUE
-
FROM
FUNDAMENTAL
TO
CLINICAL
AND
MILITARY
APPLICATIONS
383
JORDAN
MOORE,
DIEGO
ALZATE-CORREA,
DEVLEENA
DASGUPTA,
WILLIAM
LAWRENCE,
DANIEL
DODD,
CRAIG
MATHEWS,
IAN
VALERIO,
CAMERON
RINK,
NATALIA
HIGUITA-CASTRO,
AND
DANIEL
GALLEGO-PEREZ
12.1
INTRODUCTION
383
12.2
GENERAL
PRINCIPLES 385
12.2.1
PHYSICS
OF
MINIATURIZED
SYSTEMS
385
12.2.2
MATERIAL
PROPERTIES
385
12.3
AREAS
OF
STUDY
386
XII
CONTENTS
12.3.1
NEURODEVELOPMENT
386
12.3.2
NEURO-ONCOLOGY
388
12.3.3
NEURODEGENERATIVE
DISORDERS
389
12.3.4
TRAUMATIC
BRAIN
INJURY
392
12.4
APPLICATIONS
394
12.4.1
NEURON-DIRECTED
CELLULAR
REPROGRAMMING
394
12.4.2
TISSUE
NANOTRANSFECTION
396
12.4.3
CANCER
INTERROGATION
398
12.4.4
FISH
ON-CHIP
FOR
ALZHEIMER
*
S
DISEASE
401
12.4.5
ON-CHIP
BRAIN
INJURY
403
12.4.6
MILITARY
405
12.5
LIMITATIONS
AND
FUTURE
OUTLOOK
406
12.6
SUMMARY
407
REFERENCES
408
INDEX
419 |
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| any_adam_object_boolean | 1 |
| author2 | Jiang, Xingyu |
| author2_role | edt |
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| discipline_str_mv | Chemie / Pharmazie Physik |
| format | Book |
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| genre_facet | Aufsatzsammlung |
| id | DE-604.BV046929703 |
| illustrated | Illustrated |
| index_date | 2024-07-03T15:34:12Z |
| indexdate | 2024-07-10T08:57:47Z |
| institution | BVB |
| institution_GND | (DE-588)16179388-5 |
| isbn | 9783527345335 3527345337 |
| language | English |
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| owner | DE-703 |
| owner_facet | DE-703 |
| physical | xiv, 429 Seiten Illustrationen, Diagramme 24.4 cm x 17 cm |
| publishDate | 2020 |
| publishDateSearch | 2020 |
| publishDateSort | 2020 |
| publisher | Wiley-VCH |
| record_format | marc |
| series2 | Nanoscience and technology |
| spelling | Nanotechnology and microfluidics edited by Xingyu Jiang Weinheim Wiley-VCH [2020] xiv, 429 Seiten Illustrationen, Diagramme 24.4 cm x 17 cm txt rdacontent n rdamedia nc rdacarrier Nanoscience and technology Mikrofluidik (DE-588)4803438-1 gnd rswk-swf Nanotechnologie (DE-588)4327470-5 gnd rswk-swf Hardback Analytical Chemistry Analytische Chemie Chemie Chemistry Dünne Schichten, Oberflächen u. Grenzflächen Materials Science Materialwissenschaften Mikrofluidik Nanotechnologie Pharmaceutical & Medicinal Chemistry Pharmazeutische u. Medizinische Chemie Thin Films, Surfaces & Interfaces CH10: Analytische Chemie CH60: Pharmazeutische u. Medizinische Chemie MS80: Dünne Schichten, Oberflächen u. Grenzflächen 1650: Hardcover, Softcover / Chemie (DE-588)4143413-4 Aufsatzsammlung gnd-content Mikrofluidik (DE-588)4803438-1 s Nanotechnologie (DE-588)4327470-5 s DE-604 Jiang, Xingyu edt Wiley-VCH (DE-588)16179388-5 pbl Erscheint auch als Online-Ausgabe, PDF 978-3-527-81833-4 Erscheint auch als Online-Ausgabe, EPUB 978-3-527-81835-8 Erscheint auch als Online-Ausgabe 978-3-527-81834-1 X:MVB http://www.wiley-vch.de/publish/dt/books/ISBN978-3-527-34533-5/ DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=032338655&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Nanotechnology and microfluidics Mikrofluidik (DE-588)4803438-1 gnd Nanotechnologie (DE-588)4327470-5 gnd |
| subject_GND | (DE-588)4803438-1 (DE-588)4327470-5 (DE-588)4143413-4 |
| title | Nanotechnology and microfluidics |
| title_auth | Nanotechnology and microfluidics |
| title_exact_search | Nanotechnology and microfluidics |
| title_exact_search_txtP | Nanotechnology and microfluidics |
| title_full | Nanotechnology and microfluidics edited by Xingyu Jiang |
| title_fullStr | Nanotechnology and microfluidics edited by Xingyu Jiang |
| title_full_unstemmed | Nanotechnology and microfluidics edited by Xingyu Jiang |
| title_short | Nanotechnology and microfluidics |
| title_sort | nanotechnology and microfluidics |
| topic | Mikrofluidik (DE-588)4803438-1 gnd Nanotechnologie (DE-588)4327470-5 gnd |
| topic_facet | Mikrofluidik Nanotechnologie Aufsatzsammlung |
| url | http://www.wiley-vch.de/publish/dt/books/ISBN978-3-527-34533-5/ http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=032338655&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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