Influenza: the cutting edge
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Format: | Buch |
Sprache: | English |
Veröffentlicht: |
Cold Spring Harbor, New York
Cold Spring Harbor Laboratory Press
[2021]
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Schriftenreihe: | Cold Spring Harbor perspectives in medicine
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Schlagworte: | |
Online-Zugang: | Inhaltsverzeichnis Klappentext |
Beschreibung: | ix, 748 Seiten Illustrationen, Diagramme |
ISBN: | 9781621823070 |
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650 | 4 | |a Influenza | |
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Datensatz im Suchindex
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adam_text | Contents Preface, ix VIROLOGY Structure and Function of the Influenza Virus Transcription and Replication Machinery, 1 Ervin Fodor and Aartjan J.W. te Velthuis Structure and Function of Influenza Polymerase, 15 Joanna M. Wandzik, Tomas Kouba, and Stephen Cusack Hemagglutinin Structure and Activities, 33 Steven ]. Gamblin, Sébastien G. Vachieri, Xiaoli Xiong, Jie Zhang, Stephen R. Marlin, and John J. Skehel Influenza Hemagglutinin Structures and Antibody Recognition, 53 Nicholas C. Wu and lan A. Wilson The Structure, Function, and Pathobiology of the Influenza A and В Virus Ion Channels, 73 Robert A. Lamb Accessory Gene Products of Influenza A Virus, 79 Rule M. Pinto, Samantha Lycett, Eleanor Gaunt, and Paul Digard Selective Genome Packaging Mechanism of Influenza A Viruses, 99 Takeshi Noda Host Cell Factors That Interact with Influenza Virus Ribonucleoproteins, Ί13 Ecco Staller and Wendy S. Barclay The Two Sides of the Same Coin—Influenza Virus and Intracellular Signal Transduction, 139 Stephan Ludwig, Eike R. Hrincius, and Yvonne Boergeling Experimental Approaches to Identify Host Factors Important for Influenza Virus, 155 Grace Л. Schaack and Andrew Mehle Synthetic Virology: Building Viruses to Better Understand Them, 1 75 Benjamin R. tenOever Quantifying Between-Host Transmission in Influenza Virus Infections, 185 Katherine E.E. Johnson and Elodie Ghedin
Contents The Ecology and Evolution of Influenza Viruses, 201 Michelle Wille and Edward C. Holmes Influenza Reverse Genetics—Historical Perspective, 221 Gabriele Neumann INFLUENZA IN HUMANS The 1918 Influenza Pandemic and Its Legacy, 229 Jeffery K. Taubenberger and David M. Morens Human Susceptibility to Influenza Infection and Severe Disease, 2-і 1՝ Robert C. Mettelman and Paul G. Thomas Influenza in Children, 263 Jennifer Nayak, Gregory Hoy, and Aubree Gordon Influenza in High-Risk Hosts—Lessons Learned from Animal Models, 279 Rebekah Home, Nicholas Wohlgemuth, Victoria A. Meliopoulos, Kiršly R. Short, and Stacey Schultz-Cherry Human Influenza Epidemiology, 301 Sukhyun Ryu and Benjamin J. Cowling The Epidemiology, Virology, and Pathogenicity of Human Infecte e՜ with Avian Influenza Viruses, 313 Dayan Wang, Wenfei Zhu, Lei Yang, and Yuelong Shu INFLUENZÁIN ANIMALS Emerging HxNy Influenza AViruses, 331 William J. Liu, Yan Wu, Yuhai Bi, Weifeng Shi, Dayan Wang, Yi Shi, and George F. Gao H5 Influenza Viruses in Egypt, 353 Rabeh El-Shesheny, Ahmed Kandeil, Ahmed Mostafa, Mohamed A. Ali, and Richard J. Webby H7N9 Influenza Virus in China, 367 Chengjun Li and Hualan Chen H9 Influenza Viruses: An Emerging Challenge, 385 Silvia Carnaccini and Daniel R. Perez Pathobiological Origins and Evolutionary History of Highly Pathogenic Avian Influenza Viruses, 419 Dong-Hun Lee, Miria Ferreira Criado, and David E. Swayne VI
(önleniş Swine Influenza A Viruses and the Tangled Relationship with Humans, 441 Tuvis К. Anderson, Jennifer Chang, Zebulun W. Arendsee, Divya Venkatesh, Carine К. Souza, J. Brian Kimble, Nicola S. Lewis, C. Todd Davis, and Amy L. Vincent Equine Influenza, 465 Thomas M. Chambers Canine and Feline Influenza, 483 Brian R. Wasik, lan E.H. Voorhees, and Colin R. Parrish Bat-Borne Influenza A Viruses: An Awakening, 497 Kevin Ciminski and Martin Schwemmle Ferreting Out Influenza Virus Pathogenicity and Transmissibility: Past and Future Risk Assessments in the Ferret Model, 511 Jessica A. Belser, Joanna A. Pulit-Penaloza, and Taronna R. Maines IMMUNOLOGY Original Antigenic Sin: How Original? How Sinful?, 527 Jonathan W. Yewdell and Jefferson J.S. Santos Influenza Vaccines Delivered in Early Childhood Could Turn Antigenic Sin into Antigenic Blessings, 543 Michael Worobey, Stanley Plotkin, and Scott E. Hensley Immunity to Influenza Infection in Humans, 551 David J. Topham, Marta L. DeDiego, Aitor Nogales, Mark Y. Sangster, and Andrea Sant Influenza Immunization in the Context of Preexisting Immunity, 581 Susanne L. Lindeman, Ali H. Ellebedy, Carl Davis, Christiane S. Eberhardt, Rustom Antia, Ráfi Ahmed, and Veronika I. Zarnitsyna Induction and Evasion of Туре-l Interferon Responses during Influenza A Virus Infection, 595 Raquel Muñoz-Moreno, Carles Martínez-Romero, and Adolfo García-Sastre Systems Biological Analysis of Immune Response to Influenza Vaccination, 613 Mario Cortese, Amy C. Sherman, Nadine G. Rouphael, and Bali Pulendran VACCINES AND ANTIVIRALS Next-Generation Influenza
Vaccines, 629 Masaru Kanekiyo and Barney S. Graham vi
Contents Influenza Vaccine Effectiveness: New Insights and Challenges, 647 Huong Q. McLean and Edward A. Belongia Live Attenuated Cold-Adapted Influenza Vaccines, 661 Kanta Subbarao Influenza Therapeutics in Clinical Practice—Challenges and Recent Ad anees, 679 John H. Beigel and Frederick C. Hayden Influenza Polymerase Inhibitors; Mechanisms of Action and Resistance, 707 Emi Takashita Antivirals Targeting the Neuraminidase, 717 Larisa Gubareva and Teena Mohan Index, 737
Influenza The Cutting Edge Influenza is a serious infectious disease caused by different influenza vi ruses that can mutate to form new strains. Some of these strains give rise to epidemics or pandemics, infecting millions worldwide each year. Because evolutionary changes in these viruses are difficult to predict and our un derstanding of their pathogenic effects is incomplete, the development of effective vaccines and therapeutics for influenza remains challenging. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Medicine reviews cutting-edge research on the viruses that cause influenza, the molecular mechanisms of infection, the epidemiology of these viruses in humans and animals, and current strate gies for designing vaccines and antivirals. Contributors discuss all aspects of the molecular virology of influenza—the viral and host factors involved in the attachment and entry into host cells, the transcription and replication of viral genomes, and virus assembly and budding. The various factors and conditions that determine susceptibility to influenza infection and disease severity are also covered, as is our current understanding of the ecology and evolution of influenza viruses, the various subtypes, and their transmis sion and epidemiology in humans, birds, swine, bats, and other animals. In addition, the authors examine the human immune response to influ enza infection, insights gained from animal models, and technological advances in the design and delivery of vaccines and antivirals. This volume is therefore an
essential reference for all virologists, clinical and laboratory investigators, and physicians interested in reducing the global public health burden of influenza.
|
adam_txt |
Contents Preface, ix VIROLOGY Structure and Function of the Influenza Virus Transcription and Replication Machinery, 1 Ervin Fodor and Aartjan J.W. te Velthuis Structure and Function of Influenza Polymerase, 15 Joanna M. Wandzik, Tomas Kouba, and Stephen Cusack Hemagglutinin Structure and Activities, 33 Steven ]. Gamblin, Sébastien G. Vachieri, Xiaoli Xiong, Jie Zhang, Stephen R. Marlin, and John J. Skehel Influenza Hemagglutinin Structures and Antibody Recognition, 53 Nicholas C. Wu and lan A. Wilson The Structure, Function, and Pathobiology of the Influenza A and В Virus Ion Channels, 73 Robert A. Lamb Accessory Gene Products of Influenza A Virus, 79 Rule M. Pinto, Samantha Lycett, Eleanor Gaunt, and Paul Digard Selective Genome Packaging Mechanism of Influenza A Viruses, 99 Takeshi Noda Host Cell Factors That Interact with Influenza Virus Ribonucleoproteins, Ί13 Ecco Staller and Wendy S. Barclay The Two Sides of the Same Coin—Influenza Virus and Intracellular Signal Transduction, 139 Stephan Ludwig, Eike R. Hrincius, and Yvonne Boergeling Experimental Approaches to Identify Host Factors Important for Influenza Virus, 155 Grace Л. Schaack and Andrew Mehle Synthetic Virology: Building Viruses to Better Understand Them, 1 75 Benjamin R. tenOever Quantifying Between-Host Transmission in Influenza Virus Infections, 185 Katherine E.E. Johnson and Elodie Ghedin
Contents The Ecology and Evolution of Influenza Viruses, 201 Michelle Wille and Edward C. Holmes Influenza Reverse Genetics—Historical Perspective, 221 Gabriele Neumann INFLUENZA IN HUMANS The 1918 Influenza Pandemic and Its Legacy, 229 Jeffery K. Taubenberger and David M. Morens Human Susceptibility to Influenza Infection and Severe Disease, 2-і 1՝ Robert C. Mettelman and Paul G. Thomas Influenza in Children, 263 Jennifer Nayak, Gregory Hoy, and Aubree Gordon Influenza in High-Risk Hosts—Lessons Learned from Animal Models, 279 Rebekah Home, Nicholas Wohlgemuth, Victoria A. Meliopoulos, Kiršly R. Short, and Stacey Schultz-Cherry Human Influenza Epidemiology, 301 Sukhyun Ryu and Benjamin J. Cowling The Epidemiology, Virology, and Pathogenicity of Human Infecte e՜ with Avian Influenza Viruses, 313 Dayan Wang, Wenfei Zhu, Lei Yang, and Yuelong Shu INFLUENZÁIN ANIMALS Emerging HxNy Influenza AViruses, 331 William J. Liu, Yan Wu, Yuhai Bi, Weifeng Shi, Dayan Wang, Yi Shi, and George F. Gao H5 Influenza Viruses in Egypt, 353 Rabeh El-Shesheny, Ahmed Kandeil, Ahmed Mostafa, Mohamed A. Ali, and Richard J. Webby H7N9 Influenza Virus in China, 367 Chengjun Li and Hualan Chen H9 Influenza Viruses: An Emerging Challenge, 385 Silvia Carnaccini and Daniel R. Perez Pathobiological Origins and Evolutionary History of Highly Pathogenic Avian Influenza Viruses, 419 Dong-Hun Lee, Miria Ferreira Criado, and David E. Swayne VI
(önleniş Swine Influenza A Viruses and the Tangled Relationship with Humans, 441 Tuvis К. Anderson, Jennifer Chang, Zebulun W. Arendsee, Divya Venkatesh, Carine К. Souza, J. Brian Kimble, Nicola S. Lewis, C. Todd Davis, and Amy L. Vincent Equine Influenza, 465 Thomas M. Chambers Canine and Feline Influenza, 483 Brian R. Wasik, lan E.H. Voorhees, and Colin R. Parrish Bat-Borne Influenza A Viruses: An Awakening, 497 Kevin Ciminski and Martin Schwemmle Ferreting Out Influenza Virus Pathogenicity and Transmissibility: Past and Future Risk Assessments in the Ferret Model, 511 Jessica A. Belser, Joanna A. Pulit-Penaloza, and Taronna R. Maines IMMUNOLOGY Original Antigenic Sin: How Original? How Sinful?, 527 Jonathan W. Yewdell and Jefferson J.S. Santos Influenza Vaccines Delivered in Early Childhood Could Turn Antigenic Sin into Antigenic Blessings, 543 Michael Worobey, Stanley Plotkin, and Scott E. Hensley Immunity to Influenza Infection in Humans, 551 David J. Topham, Marta L. DeDiego, Aitor Nogales, Mark Y. Sangster, and Andrea Sant Influenza Immunization in the Context of Preexisting Immunity, 581 Susanne L. Lindeman, Ali H. Ellebedy, Carl Davis, Christiane S. Eberhardt, Rustom Antia, Ráfi Ahmed, and Veronika I. Zarnitsyna Induction and Evasion of Туре-l Interferon Responses during Influenza A Virus Infection, 595 Raquel Muñoz-Moreno, Carles Martínez-Romero, and Adolfo García-Sastre Systems Biological Analysis of Immune Response to Influenza Vaccination, 613 Mario Cortese, Amy C. Sherman, Nadine G. Rouphael, and Bali Pulendran VACCINES AND ANTIVIRALS Next-Generation Influenza
Vaccines, 629 Masaru Kanekiyo and Barney S. Graham vi
Contents Influenza Vaccine Effectiveness: New Insights and Challenges, 647 Huong Q. McLean and Edward A. Belongia Live Attenuated Cold-Adapted Influenza Vaccines, 661 Kanta Subbarao Influenza Therapeutics in Clinical Practice—Challenges and Recent Ad anees, 679 John H. Beigel and Frederick C. Hayden Influenza Polymerase Inhibitors; Mechanisms of Action and Resistance, 707 Emi Takashita Antivirals Targeting the Neuraminidase, 717 Larisa Gubareva and Teena Mohan Index, 737
Influenza The Cutting Edge Influenza is a serious infectious disease caused by different influenza vi ruses that can mutate to form new strains. Some of these strains give rise to epidemics or pandemics, infecting millions worldwide each year. Because evolutionary changes in these viruses are difficult to predict and our un derstanding of their pathogenic effects is incomplete, the development of effective vaccines and therapeutics for influenza remains challenging. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Medicine reviews cutting-edge research on the viruses that cause influenza, the molecular mechanisms of infection, the epidemiology of these viruses in humans and animals, and current strate gies for designing vaccines and antivirals. Contributors discuss all aspects of the molecular virology of influenza—the viral and host factors involved in the attachment and entry into host cells, the transcription and replication of viral genomes, and virus assembly and budding. The various factors and conditions that determine susceptibility to influenza infection and disease severity are also covered, as is our current understanding of the ecology and evolution of influenza viruses, the various subtypes, and their transmis sion and epidemiology in humans, birds, swine, bats, and other animals. In addition, the authors examine the human immune response to influ enza infection, insights gained from animal models, and technological advances in the design and delivery of vaccines and antivirals. This volume is therefore an
essential reference for all virologists, clinical and laboratory investigators, and physicians interested in reducing the global public health burden of influenza. |
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spelling | Influenza the cutting edge edited by Gabriele Neumann (University of Wisconsin-Madison), Yoshihiro Kawaoka (University of Wisconsin-Madison, University of Tokyo) Cold Spring Harbor, New York Cold Spring Harbor Laboratory Press [2021] © 2021 ix, 748 Seiten Illustrationen, Diagramme txt rdacontent n rdamedia nc rdacarrier Cold Spring Harbor perspectives in medicine Immunology Infectious & contagious diseases Respiratory medicine SCIENCE / Life Sciences / Virology MEDICAL / Immunology MEDICAL / Infectious Diseases MEDICAL / Pulmonary & Thoracic Medicine Influenza Influenza viruses Influenza vaccines (DE-588)4143413-4 Aufsatzsammlung gnd-content Neumann, Gabriele edt wpr aut Kawaoka, Yoshihiro 1955- (DE-588)129046868 edt wpr Erscheint auch als Online-Ausgabe 978-1-621823-09-4 Erscheint auch als Online-Ausgabe, EPUB 978-1-621823-08-7 Digitalisierung UB Regensburg - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=032305975&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Digitalisierung UB Regensburg - ADAM Catalogue Enrichment application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=032305975&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Klappentext |
spellingShingle | Neumann, Gabriele Influenza the cutting edge Immunology Infectious & contagious diseases Respiratory medicine SCIENCE / Life Sciences / Virology MEDICAL / Immunology MEDICAL / Infectious Diseases MEDICAL / Pulmonary & Thoracic Medicine Influenza Influenza viruses Influenza vaccines |
subject_GND | (DE-588)4143413-4 |
title | Influenza the cutting edge |
title_auth | Influenza the cutting edge |
title_exact_search | Influenza the cutting edge |
title_exact_search_txtP | Influenza the cutting edge |
title_full | Influenza the cutting edge edited by Gabriele Neumann (University of Wisconsin-Madison), Yoshihiro Kawaoka (University of Wisconsin-Madison, University of Tokyo) |
title_fullStr | Influenza the cutting edge edited by Gabriele Neumann (University of Wisconsin-Madison), Yoshihiro Kawaoka (University of Wisconsin-Madison, University of Tokyo) |
title_full_unstemmed | Influenza the cutting edge edited by Gabriele Neumann (University of Wisconsin-Madison), Yoshihiro Kawaoka (University of Wisconsin-Madison, University of Tokyo) |
title_short | Influenza |
title_sort | influenza the cutting edge |
title_sub | the cutting edge |
topic | Immunology Infectious & contagious diseases Respiratory medicine SCIENCE / Life Sciences / Virology MEDICAL / Immunology MEDICAL / Infectious Diseases MEDICAL / Pulmonary & Thoracic Medicine Influenza Influenza viruses Influenza vaccines |
topic_facet | Immunology Infectious & contagious diseases Respiratory medicine SCIENCE / Life Sciences / Virology MEDICAL / Immunology MEDICAL / Infectious Diseases MEDICAL / Pulmonary & Thoracic Medicine Influenza Influenza viruses Influenza vaccines Aufsatzsammlung |
url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=032305975&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=032305975&sequence=000003&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA |
work_keys_str_mv | AT neumanngabriele influenzathecuttingedge AT kawaokayoshihiro influenzathecuttingedge |