Pre-Analytics of Pathological Specimens in Oncology:
This book presents an overview of the most important current developments in the pre-analytical handling of tissue. It addresses in particular potential ways to improve the situation whereby methods employed in the pre-analytical phase - the period from surgical removal of tissue to the start of pat...
Gespeichert in:
| Format: | Elektronisch E-Book |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Cham
Springer International Publishing
2015
|
| Ausgabe: | 1st ed. 2015 |
| Schriftenreihe: | Recent Results in Cancer Research
|
| Schlagworte: | |
| Online-Zugang: | UBR01 Volltext |
| Zusammenfassung: | This book presents an overview of the most important current developments in the pre-analytical handling of tissue. It addresses in particular potential ways to improve the situation whereby methods employed in the pre-analytical phase - the period from surgical removal of tissue to the start of pathological processing - have remained essentially unchanged for decades with only modest standardization. It is examined how the pre-analytical period can be optimized, resulting not only in an increase in diagnostic quality but also in a reduction in processing time and costs. Among the key topics examined are the so-called cold ischemia time between tissue removal and fixation, the potential superiority of vacuum-based preservation over immediate formalin fixation, two-temperature fixation, molecular analysis methods, and the pre-analytics of specimens from particular tissues. Readers will find this book to be an important update that reveals the full importance of the pre-analytical phase for quality of pathological work-up |
| Beschreibung: | What Is Pre-Analytics in Surgical Pathology? -- Histologic Validation of Vacuum Sealed Formalin -- Free Tissue Preservation and Transport System -- Pre-Analytics and Molecular Pathology -- Experiences in Vacuum Preparation of Routine Specimens -- Tissue Heterogeneity as a Pre-Analytical Source of Variability -- Vacuum Fixation of Breast Specimens Before Grossing -- How Do Short Fixation and Rapid Microwave Processing Affect Her2 Testing? -- Current Projects in Pre-Analytics - Where to Go? -- Nucleic Acid Extraction from FFPE Tissue as Critical Preanalytic Step for NGS Applications -- Experiences With Pre-Analytics of Lung Specimen -- Experiences With Pre-Analytics of GI-Specimen -- Bone Marrow Work-Up -- Two-Temperature Fixation Preserves Activation Status with High Efficiency -- Towards the Lean Lab. The Industry Challenge. |
| Beschreibung: | 1 Online Ressource (VI, 133 Seiten, 65 Illustrationen, 61 Illustrationen in Farbe) |
| ISBN: | 9783319139579 |
| DOI: | 10.1007/978-3-319-13957-9 |
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| 520 | |a This book presents an overview of the most important current developments in the pre-analytical handling of tissue. It addresses in particular potential ways to improve the situation whereby methods employed in the pre-analytical phase - the period from surgical removal of tissue to the start of pathological processing - have remained essentially unchanged for decades with only modest standardization. It is examined how the pre-analytical period can be optimized, resulting not only in an increase in diagnostic quality but also in a reduction in processing time and costs. Among the key topics examined are the so-called cold ischemia time between tissue removal and fixation, the potential superiority of vacuum-based preservation over immediate formalin fixation, two-temperature fixation, molecular analysis methods, and the pre-analytics of specimens from particular tissues. Readers will find this book to be an important update that reveals the full importance of the pre-analytical phase for quality of pathological work-up | ||
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| 700 | 1 | |a Bussolati, Gianni |e Sonstige |4 oth | |
| 700 | 1 | |a Winterfeld, Moritz |e Sonstige |4 oth | |
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| doi_str_mv | 10.1007/978-3-319-13957-9 |
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| id | DE-604.BV046815889 |
| illustrated | Not Illustrated |
| index_date | 2024-07-03T15:00:10Z |
| indexdate | 2024-07-10T08:54:38Z |
| institution | BVB |
| isbn | 9783319139579 |
| language | English |
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| physical | 1 Online Ressource (VI, 133 Seiten, 65 Illustrationen, 61 Illustrationen in Farbe) |
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| publisher | Springer International Publishing |
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| series2 | Recent Results in Cancer Research |
| spelling | Pre-Analytics of Pathological Specimens in Oncology edited by Manfred Dietel, Christian Wittekind, Gianni Bussolati, Moritz Winterfeld 1st ed. 2015 Cham Springer International Publishing 2015 1 Online Ressource (VI, 133 Seiten, 65 Illustrationen, 61 Illustrationen in Farbe) txt rdacontent c rdamedia cr rdacarrier Recent Results in Cancer Research What Is Pre-Analytics in Surgical Pathology? -- Histologic Validation of Vacuum Sealed Formalin -- Free Tissue Preservation and Transport System -- Pre-Analytics and Molecular Pathology -- Experiences in Vacuum Preparation of Routine Specimens -- Tissue Heterogeneity as a Pre-Analytical Source of Variability -- Vacuum Fixation of Breast Specimens Before Grossing -- How Do Short Fixation and Rapid Microwave Processing Affect Her2 Testing? -- Current Projects in Pre-Analytics - Where to Go? -- Nucleic Acid Extraction from FFPE Tissue as Critical Preanalytic Step for NGS Applications -- Experiences With Pre-Analytics of Lung Specimen -- Experiences With Pre-Analytics of GI-Specimen -- Bone Marrow Work-Up -- Two-Temperature Fixation Preserves Activation Status with High Efficiency -- Towards the Lean Lab. The Industry Challenge. This book presents an overview of the most important current developments in the pre-analytical handling of tissue. It addresses in particular potential ways to improve the situation whereby methods employed in the pre-analytical phase - the period from surgical removal of tissue to the start of pathological processing - have remained essentially unchanged for decades with only modest standardization. It is examined how the pre-analytical period can be optimized, resulting not only in an increase in diagnostic quality but also in a reduction in processing time and costs. Among the key topics examined are the so-called cold ischemia time between tissue removal and fixation, the potential superiority of vacuum-based preservation over immediate formalin fixation, two-temperature fixation, molecular analysis methods, and the pre-analytics of specimens from particular tissues. Readers will find this book to be an important update that reveals the full importance of the pre-analytical phase for quality of pathological work-up Oncology Pathology Surgery Laboratory medicine Dietel, Manfred Sonstige oth Wittekind, Christian Sonstige oth Bussolati, Gianni Sonstige oth Winterfeld, Moritz Sonstige oth Erscheint auch als Druck-Ausgabe 9783319139586 Erscheint auch als Druck-Ausgabe 9783319139562 Erscheint auch als Druck-Ausgabe 9783319349824 https://doi.org/10.1007/978-3-319-13957-9 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Pre-Analytics of Pathological Specimens in Oncology Oncology Pathology Surgery Laboratory medicine |
| title | Pre-Analytics of Pathological Specimens in Oncology |
| title_auth | Pre-Analytics of Pathological Specimens in Oncology |
| title_exact_search | Pre-Analytics of Pathological Specimens in Oncology |
| title_exact_search_txtP | Pre-Analytics of Pathological Specimens in Oncology |
| title_full | Pre-Analytics of Pathological Specimens in Oncology edited by Manfred Dietel, Christian Wittekind, Gianni Bussolati, Moritz Winterfeld |
| title_fullStr | Pre-Analytics of Pathological Specimens in Oncology edited by Manfred Dietel, Christian Wittekind, Gianni Bussolati, Moritz Winterfeld |
| title_full_unstemmed | Pre-Analytics of Pathological Specimens in Oncology edited by Manfred Dietel, Christian Wittekind, Gianni Bussolati, Moritz Winterfeld |
| title_short | Pre-Analytics of Pathological Specimens in Oncology |
| title_sort | pre analytics of pathological specimens in oncology |
| topic | Oncology Pathology Surgery Laboratory medicine |
| topic_facet | Oncology Pathology Surgery Laboratory medicine |
| url | https://doi.org/10.1007/978-3-319-13957-9 |
| work_keys_str_mv | AT dietelmanfred preanalyticsofpathologicalspecimensinoncology AT wittekindchristian preanalyticsofpathologicalspecimensinoncology AT bussolatigianni preanalyticsofpathologicalspecimensinoncology AT winterfeldmoritz preanalyticsofpathologicalspecimensinoncology |