An Information Technology Framework for Predictive, Preventive and Personalised Medicine: A Use-Case with Hepatocellular Carcinoma

This book explores how PPPM, clinical practice, and basic research could be best served by information technology (IT). A use-case was developed for hepatocellular carcinoma (HCC). The subject was approached with four interrelated tasks: (1) review of clinical practices relating to HCC; (2) propose...

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Format: Elektronisch E-Book
Sprache:English
Veröffentlicht: Cham Springer International Publishing 2015
Ausgabe:1st ed. 2015
Schriftenreihe:Advances in Predictive, Preventive and Personalised Medicine
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Online-Zugang:UBR01
URL des Erstveröffentlichers
Zusammenfassung:This book explores how PPPM, clinical practice, and basic research could be best served by information technology (IT). A use-case was developed for hepatocellular carcinoma (HCC). The subject was approached with four interrelated tasks: (1) review of clinical practices relating to HCC; (2) propose an IT system relating to HCC, including clinical decision support and research needs; (3) determine how a clinical liver cancer center can contribute; and, (4) examine the enhancements and impact that the first three tasks will have on the management of HCC. An IT System for Personalized Medicine (ITS-PM) for HCC will provide the means to identify and determine the relative value of the wide number of variables, including clinical assessment of the patient -- functional status, liver function, degree of cirrhosis, and comorbidities; tumor biology, at a molecular, genetic and anatomic level; tumor burden and individual patient response; medical and operative treatments and their outcomes
Beschreibung:Preface -- Introduction -- The Digital Patient Model and Model Guided Therapy -- Hepatocellular Carcinoma and Patient Assessment -- Imaging in Hepatocellular Carcinoma: Radiologic Assessment -- Imaging in Hepatocellular Carcinoma: PET/CT -- Personalized Chemotherapy for Hepatocellular Carcinoma -- Surgical Treatment for Hepatocellular Carcinoma.-  Minimally Invasive Therapies for Hepatocellular Cancer: Ablation Technologies -- Chapter 9  Minimally Invasive Therapies for Hepatocellular Cancer: Ablation Therapies -- Minimally Invasive Therapies for Hepatocellular Cancer:Catheter-Directed Therapies -- Radiation Oncology in the Treatment of Hepatocellular Carcinoma -- Design of an IT System for Hepatocellular Carcinoma -- Outlook and Expert Recommendations for Predictive, Preventive and Personalized Medicine and Hepatocellular Carcinoma
Beschreibung:1 Online Ressource (XX, 130 Seiten, 23 Illustrationen, 15 Illustrationen in Farbe)
ISBN:9783319121666
DOI:10.1007/978-3-319-12166-6

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