Behçet's Disease: From Genetics to Therapies
This book, besides reviewing basic and clinical aspects of Behçet's disease, covers the latest findings, including genetic studies and treatment with biologics for the disease. Although the cause of Behçet's disease is still unknown, it is well known that genetic factors, such as HLA-B51...
Gespeichert in:
| Format: | Elektronisch E-Book |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Tokyo
Springer Japan
2015
|
| Ausgabe: | 1st ed. 2015 |
| Schlagworte: | |
| Online-Zugang: | UBR01 URL des Erstveröffentlichers |
| Zusammenfassung: | This book, besides reviewing basic and clinical aspects of Behçet's disease, covers the latest findings, including genetic studies and treatment with biologics for the disease. Although the cause of Behçet's disease is still unknown, it is well known that genetic factors, such as HLA-B51, are involved in its development. Recently, novel susceptibility loci including IL10, IL23R-IL12RB2, and endoplasmic reticulum aminopeptidase 1 have been identified, providing new insights into the pathogenesis of the disease. In addition to basic research, the beneficial efficacy of anti-TNF-alpha monoclonal antibodies has also been suggested for not only uveitis associated with the disease but also other subtypes of the disease such as entero-, vasculo-, and neuro- Behçet's disease. Behçet's Disease: From Genetics to Therapies provides essential information both for basic researchers working in the fields of immunology, inflammation, and genetics, and for clinical physicians who are interested in Behçet's disease, such as ophthalmologists, rheumatologists, dermatologists, gastroenterologists, neurologists, and vascular surgeons |
| Beschreibung: | 1. Overview -- 2. The Immunopathology of Behcet's Disease -- 3. Genetics -- 4. Ocular Involvement -- 5. Vascular Involvement of Behçet's Disease -- 6. Neurological Involvement -- 7. Gastrointestinal Involvement -- 8. Mucocutaneous Manifestations -- 9. Perspective |
| Beschreibung: | 1 Online Ressource (IX, 176 Seiten, 38 Illustrationen, 31 Illustrationen in Farbe) |
| ISBN: | 9784431544876 |
| DOI: | 10.1007/978-4-431-54487-6 |
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| 520 | |a This book, besides reviewing basic and clinical aspects of Behçet's disease, covers the latest findings, including genetic studies and treatment with biologics for the disease. Although the cause of Behçet's disease is still unknown, it is well known that genetic factors, such as HLA-B51, are involved in its development. Recently, novel susceptibility loci including IL10, IL23R-IL12RB2, and endoplasmic reticulum aminopeptidase 1 have been identified, providing new insights into the pathogenesis of the disease. In addition to basic research, the beneficial efficacy of anti-TNF-alpha monoclonal antibodies has also been suggested for not only uveitis associated with the disease but also other subtypes of the disease such as entero-, vasculo-, and neuro- Behçet's disease. Behçet's Disease: From Genetics to Therapies provides essential information both for basic researchers working in the fields of immunology, inflammation, and genetics, and for clinical physicians who are interested in Behçet's disease, such as ophthalmologists, rheumatologists, dermatologists, gastroenterologists, neurologists, and vascular surgeons | ||
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| discipline | Medizin |
| discipline_str_mv | Medizin |
| doi_str_mv | 10.1007/978-4-431-54487-6 |
| edition | 1st ed. 2015 |
| format | Electronic eBook |
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| id | DE-604.BV046815290 |
| illustrated | Not Illustrated |
| index_date | 2024-07-03T15:00:03Z |
| indexdate | 2024-07-10T08:54:36Z |
| institution | BVB |
| isbn | 9784431544876 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-032223768 |
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| physical | 1 Online Ressource (IX, 176 Seiten, 38 Illustrationen, 31 Illustrationen in Farbe) |
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| spelling | Behçet's Disease From Genetics to Therapies edited by Yoshiaki Ishigatsubo 1st ed. 2015 Tokyo Springer Japan 2015 1 Online Ressource (IX, 176 Seiten, 38 Illustrationen, 31 Illustrationen in Farbe) txt rdacontent c rdamedia cr rdacarrier 1. Overview -- 2. The Immunopathology of Behcet's Disease -- 3. Genetics -- 4. Ocular Involvement -- 5. Vascular Involvement of Behçet's Disease -- 6. Neurological Involvement -- 7. Gastrointestinal Involvement -- 8. Mucocutaneous Manifestations -- 9. Perspective This book, besides reviewing basic and clinical aspects of Behçet's disease, covers the latest findings, including genetic studies and treatment with biologics for the disease. Although the cause of Behçet's disease is still unknown, it is well known that genetic factors, such as HLA-B51, are involved in its development. Recently, novel susceptibility loci including IL10, IL23R-IL12RB2, and endoplasmic reticulum aminopeptidase 1 have been identified, providing new insights into the pathogenesis of the disease. In addition to basic research, the beneficial efficacy of anti-TNF-alpha monoclonal antibodies has also been suggested for not only uveitis associated with the disease but also other subtypes of the disease such as entero-, vasculo-, and neuro- Behçet's disease. Behçet's Disease: From Genetics to Therapies provides essential information both for basic researchers working in the fields of immunology, inflammation, and genetics, and for clinical physicians who are interested in Behçet's disease, such as ophthalmologists, rheumatologists, dermatologists, gastroenterologists, neurologists, and vascular surgeons Rheumatology Allergy Dermatology Ophthalmology Gastroenterology Ishigatsubo, Yoshiaki Sonstige oth Erscheint auch als Druck-Ausgabe 9784431544869 Erscheint auch als Druck-Ausgabe 9784431544883 Erscheint auch als Druck-Ausgabe 9784431561705 https://doi.org/10.1007/978-4-431-54487-6 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Behçet's Disease From Genetics to Therapies Rheumatology Allergy Dermatology Ophthalmology Gastroenterology |
| title | Behçet's Disease From Genetics to Therapies |
| title_auth | Behçet's Disease From Genetics to Therapies |
| title_exact_search | Behçet's Disease From Genetics to Therapies |
| title_exact_search_txtP | Behçet's Disease From Genetics to Therapies |
| title_full | Behçet's Disease From Genetics to Therapies edited by Yoshiaki Ishigatsubo |
| title_fullStr | Behçet's Disease From Genetics to Therapies edited by Yoshiaki Ishigatsubo |
| title_full_unstemmed | Behçet's Disease From Genetics to Therapies edited by Yoshiaki Ishigatsubo |
| title_short | Behçet's Disease |
| title_sort | behcet s disease from genetics to therapies |
| title_sub | From Genetics to Therapies |
| topic | Rheumatology Allergy Dermatology Ophthalmology Gastroenterology |
| topic_facet | Rheumatology Allergy Dermatology Ophthalmology Gastroenterology |
| url | https://doi.org/10.1007/978-4-431-54487-6 |
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