Medullary Thyroid Carcinoma: Biology - Management - Treatment
This book offers a comprehensive overview of medullary thyroid carcinoma, both in the more common sporadic form and in the familial form, multiple endocrine neoplasia (MEN) types 2A and 2B. The coverage includes, but is not limited to, molecular biology and genetics, pathology, clinical presentation...
Gespeichert in:
| Format: | Elektronisch E-Book |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Cham
Springer International Publishing
2015
|
| Ausgabe: | 1st ed. 2015 |
| Schriftenreihe: | Recent Results in Cancer Research
|
| Schlagworte: | |
| Online-Zugang: | UBR01 URL des Erstveröffentlichers |
| Zusammenfassung: | This book offers a comprehensive overview of medullary thyroid carcinoma, both in the more common sporadic form and in the familial form, multiple endocrine neoplasia (MEN) types 2A and 2B. The coverage includes, but is not limited to, molecular biology and genetics, pathology, clinical presentation, imaging techniques, surgical treatment, and follow-up. The role of calcitonin as a highly sensitive and specific tumor marker for the screening, diagnosis, and follow-up of MTC and metastatic disease is described, and the significance of other tumor markers is also considered. With regard to treatment, the use of thyroidectomy is fully discussed, including in children carrying the mutations in the RET proto-oncogene considered causative for MEN 2. Additionally, the value of tyrosine kinase inhibitors as the most effective treatment modality in patients with a large tumor burden or rapid tumor growth, or both, is explained. Medullary Thyroid Carcinoma and Multiple Endocrine Neoplasia Type 2 will be an ideal source of up-to-date information for a wide range of practitioners, including endocrinologists, oncologists, internal medicine specialists, geneticists, and nuclear medicine physicians |
| Beschreibung: | Thyroid C-Cell Biology and Oncogenic Transformation -- Histopathology of C cells and medullary thyroid carcinoma -- Epidemiology and clinical presentation of Medullary Thyroid Carcinoma -- Medullary thyroid carcinoma: Imaging -- Calcitonin as a Biomarker for Medullary Thyroid Carcinoma -- Hereditary Medullary Thyroid Cancer, Genotype phenotype correlation -- Pheochromocytomas in Multiple Endocrine Neoplasia 2 -- Primary hyperparathyroidism in Multiple Endocrine Neoplasia 2 Syndrome -- Surgical treatment of medullary thyroid carcinoma -- Long term follow up in medullary thyroid carcinoma -- Use of Tyrosine Kinase Inhibitors for Treatment of Medullary Thyroid Carcinoma |
| Beschreibung: | 1 Online Ressource (VIII, 249 Seiten,) |
| ISBN: | 9783319225425 |
| DOI: | 10.1007/978-3-319-22542-5 |
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| 520 | |a This book offers a comprehensive overview of medullary thyroid carcinoma, both in the more common sporadic form and in the familial form, multiple endocrine neoplasia (MEN) types 2A and 2B. The coverage includes, but is not limited to, molecular biology and genetics, pathology, clinical presentation, imaging techniques, surgical treatment, and follow-up. The role of calcitonin as a highly sensitive and specific tumor marker for the screening, diagnosis, and follow-up of MTC and metastatic disease is described, and the significance of other tumor markers is also considered. With regard to treatment, the use of thyroidectomy is fully discussed, including in children carrying the mutations in the RET proto-oncogene considered causative for MEN 2. Additionally, the value of tyrosine kinase inhibitors as the most effective treatment modality in patients with a large tumor burden or rapid tumor growth, or both, is explained. Medullary Thyroid Carcinoma and Multiple Endocrine Neoplasia Type 2 will be an ideal source of up-to-date information for a wide range of practitioners, including endocrinologists, oncologists, internal medicine specialists, geneticists, and nuclear medicine physicians | ||
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| dewey-ones | 616 - Diseases |
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| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| discipline_str_mv | Medizin |
| doi_str_mv | 10.1007/978-3-319-22542-5 |
| edition | 1st ed. 2015 |
| format | Electronic eBook |
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| id | DE-604.BV046813048 |
| illustrated | Not Illustrated |
| index_date | 2024-07-03T14:59:22Z |
| indexdate | 2024-07-10T08:54:33Z |
| institution | BVB |
| isbn | 9783319225425 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-032221562 |
| oclc_num | 1190908652 |
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| owner_facet | DE-355 DE-BY-UBR |
| physical | 1 Online Ressource (VIII, 249 Seiten,) |
| psigel | ZDB-2-SME ZDB-2-SME_2015 ZDB-2-SME ZDB-2-SME_2015 |
| publishDate | 2015 |
| publishDateSearch | 2015 |
| publishDateSort | 2015 |
| publisher | Springer International Publishing |
| record_format | marc |
| series2 | Recent Results in Cancer Research |
| spelling | Medullary Thyroid Carcinoma Biology - Management - Treatment edited by Friedhelm Raue 1st ed. 2015 Cham Springer International Publishing 2015 1 Online Ressource (VIII, 249 Seiten,) txt rdacontent c rdamedia cr rdacarrier Recent Results in Cancer Research Thyroid C-Cell Biology and Oncogenic Transformation -- Histopathology of C cells and medullary thyroid carcinoma -- Epidemiology and clinical presentation of Medullary Thyroid Carcinoma -- Medullary thyroid carcinoma: Imaging -- Calcitonin as a Biomarker for Medullary Thyroid Carcinoma -- Hereditary Medullary Thyroid Cancer, Genotype phenotype correlation -- Pheochromocytomas in Multiple Endocrine Neoplasia 2 -- Primary hyperparathyroidism in Multiple Endocrine Neoplasia 2 Syndrome -- Surgical treatment of medullary thyroid carcinoma -- Long term follow up in medullary thyroid carcinoma -- Use of Tyrosine Kinase Inhibitors for Treatment of Medullary Thyroid Carcinoma This book offers a comprehensive overview of medullary thyroid carcinoma, both in the more common sporadic form and in the familial form, multiple endocrine neoplasia (MEN) types 2A and 2B. The coverage includes, but is not limited to, molecular biology and genetics, pathology, clinical presentation, imaging techniques, surgical treatment, and follow-up. The role of calcitonin as a highly sensitive and specific tumor marker for the screening, diagnosis, and follow-up of MTC and metastatic disease is described, and the significance of other tumor markers is also considered. With regard to treatment, the use of thyroidectomy is fully discussed, including in children carrying the mutations in the RET proto-oncogene considered causative for MEN 2. Additionally, the value of tyrosine kinase inhibitors as the most effective treatment modality in patients with a large tumor burden or rapid tumor growth, or both, is explained. Medullary Thyroid Carcinoma and Multiple Endocrine Neoplasia Type 2 will be an ideal source of up-to-date information for a wide range of practitioners, including endocrinologists, oncologists, internal medicine specialists, geneticists, and nuclear medicine physicians Oncology Endocrinology Human genetics Nuclear medicine Raue, Friedhelm Sonstige oth Erscheint auch als Druck-Ausgabe 9783319225418 Erscheint auch als Druck-Ausgabe 9783319225432 Erscheint auch als Druck-Ausgabe 9783319362601 https://doi.org/10.1007/978-3-319-22542-5 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Medullary Thyroid Carcinoma Biology - Management - Treatment Oncology Endocrinology Human genetics Nuclear medicine |
| title | Medullary Thyroid Carcinoma Biology - Management - Treatment |
| title_auth | Medullary Thyroid Carcinoma Biology - Management - Treatment |
| title_exact_search | Medullary Thyroid Carcinoma Biology - Management - Treatment |
| title_exact_search_txtP | Medullary Thyroid Carcinoma Biology - Management - Treatment |
| title_full | Medullary Thyroid Carcinoma Biology - Management - Treatment edited by Friedhelm Raue |
| title_fullStr | Medullary Thyroid Carcinoma Biology - Management - Treatment edited by Friedhelm Raue |
| title_full_unstemmed | Medullary Thyroid Carcinoma Biology - Management - Treatment edited by Friedhelm Raue |
| title_short | Medullary Thyroid Carcinoma |
| title_sort | medullary thyroid carcinoma biology management treatment |
| title_sub | Biology - Management - Treatment |
| topic | Oncology Endocrinology Human genetics Nuclear medicine |
| topic_facet | Oncology Endocrinology Human genetics Nuclear medicine |
| url | https://doi.org/10.1007/978-3-319-22542-5 |
| work_keys_str_mv | AT rauefriedhelm medullarythyroidcarcinomabiologymanagementtreatment |