Silkworm biofactory: silk to biology
While silk derived from silkworm has been of economic importance for centuries, more recently silkworm has been found to have utility in biomedicine. This has attracted attention for expressing eukaryotic recombinant proteins, which require post-translational modifications. In 1985 Dr. Susumu Maeda...
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Format: | Elektronisch E-Book |
Sprache: | English |
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Boca Raton, FL
CRC Press, Taylor & Francis Group
[2018]
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Schlagworte: | |
Online-Zugang: | Volltext |
Zusammenfassung: | While silk derived from silkworm has been of economic importance for centuries, more recently silkworm has been found to have utility in biomedicine. This has attracted attention for expressing eukaryotic recombinant proteins, which require post-translational modifications. In 1985 Dr. Susumu Maeda demonstrated that silkworm larvae could produce a functional human-interferon. Since then various techniques have been developed to express recombinant proteins in silkworm. With the development of the Bombyx mori nucleopolyhedrovirus (BmNPV) bacmid system, which is capable of replicating in both Escherichia coli and Bombyx mori derived cell lines or silkworm, silkworm larvae or pupae have been used for the expression system for recombinant protein production. This method has the advantage of a bacmid, in that it can be easily prepared for sufficient bacmid DNA for subsequent expression in silkworm. It is potentially a big breakthrough in production of recombinant eukaryotic proteins and viruses, which will be a powerful tool in a new proteome era. This volume contributes to the advancement of our knowledge in the subject, for example gene expression systems and silkworm research, and focuses on silkworm biofactories for the recombinant protein production and commercial applications of proteins |
Beschreibung: | OCLC-licensed vendor bibliographic record |
Beschreibung: | 1 online resource |
ISBN: | 9780429448881 0429448880 9780429829048 0429829043 9780429829024 0429829027 9780429829031 0429829035 |
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dewey-ones | 638 - Insect culture |
dewey-raw | 638/.2 |
dewey-search | 638/.2 |
dewey-sort | 3638 12 |
dewey-tens | 630 - Agriculture and related technologies |
discipline | Agrar-/Forst-/Ernährungs-/Haushaltswissenschaft / Gartenbau |
discipline_str_mv | Agrar-/Forst-/Ernährungs-/Haushaltswissenschaft / Gartenbau |
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index_date | 2024-07-03T14:08:06Z |
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isbn | 9780429448881 0429448880 9780429829048 0429829043 9780429829024 0429829027 9780429829031 0429829035 |
language | English |
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spelling | Silkworm biofactory silk to biology editors: Enoch Y. Park, Katsumi Maenaka Boca Raton, FL CRC Press, Taylor & Francis Group [2018] 1 online resource txt rdacontent c rdamedia cr rdacarrier OCLC-licensed vendor bibliographic record While silk derived from silkworm has been of economic importance for centuries, more recently silkworm has been found to have utility in biomedicine. This has attracted attention for expressing eukaryotic recombinant proteins, which require post-translational modifications. In 1985 Dr. Susumu Maeda demonstrated that silkworm larvae could produce a functional human-interferon. Since then various techniques have been developed to express recombinant proteins in silkworm. With the development of the Bombyx mori nucleopolyhedrovirus (BmNPV) bacmid system, which is capable of replicating in both Escherichia coli and Bombyx mori derived cell lines or silkworm, silkworm larvae or pupae have been used for the expression system for recombinant protein production. This method has the advantage of a bacmid, in that it can be easily prepared for sufficient bacmid DNA for subsequent expression in silkworm. It is potentially a big breakthrough in production of recombinant eukaryotic proteins and viruses, which will be a powerful tool in a new proteome era. This volume contributes to the advancement of our knowledge in the subject, for example gene expression systems and silkworm research, and focuses on silkworm biofactories for the recombinant protein production and commercial applications of proteins TECHNOLOGY & ENGINEERING / Agriculture / General bisacsh SCIENCE / Life Sciences / Zoology / Entomology bisacsh Silkworms / Research Silkworms / Genetic engineering Animal biotechnology Park, Enoch Y. edt Maenaka, Katsumi edt https://www.taylorfrancis.com/books/9780429448881 Verlag URL des Erstveröffentlichers Volltext |
spellingShingle | Silkworm biofactory silk to biology TECHNOLOGY & ENGINEERING / Agriculture / General bisacsh SCIENCE / Life Sciences / Zoology / Entomology bisacsh Silkworms / Research Silkworms / Genetic engineering Animal biotechnology |
title | Silkworm biofactory silk to biology |
title_auth | Silkworm biofactory silk to biology |
title_exact_search | Silkworm biofactory silk to biology |
title_exact_search_txtP | Silkworm biofactory silk to biology |
title_full | Silkworm biofactory silk to biology editors: Enoch Y. Park, Katsumi Maenaka |
title_fullStr | Silkworm biofactory silk to biology editors: Enoch Y. Park, Katsumi Maenaka |
title_full_unstemmed | Silkworm biofactory silk to biology editors: Enoch Y. Park, Katsumi Maenaka |
title_short | Silkworm biofactory |
title_sort | silkworm biofactory silk to biology |
title_sub | silk to biology |
topic | TECHNOLOGY & ENGINEERING / Agriculture / General bisacsh SCIENCE / Life Sciences / Zoology / Entomology bisacsh Silkworms / Research Silkworms / Genetic engineering Animal biotechnology |
topic_facet | TECHNOLOGY & ENGINEERING / Agriculture / General SCIENCE / Life Sciences / Zoology / Entomology Silkworms / Research Silkworms / Genetic engineering Animal biotechnology |
url | https://www.taylorfrancis.com/books/9780429448881 |
work_keys_str_mv | AT parkenochy silkwormbiofactorysilktobiology AT maenakakatsumi silkwormbiofactorysilktobiology |