Protein chemistry:
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | English |
| Veröffentlicht: |
Berlin ; Boston
De Gruyter
[2020]
|
| Schriftenreihe: | De Gruyter graduate
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | X, 236 Seiten Illustrationen, Diagramme (farbig) |
| ISBN: | 9783110566161 |
Internformat
MARC
| LEADER | 00000nam a2200000 c 4500 | ||
|---|---|---|---|
| 001 | BV046249108 | ||
| 003 | DE-604 | ||
| 005 | 20240904 | ||
| 007 | t | ||
| 008 | 191112s2020 a||| |||| 00||| eng d | ||
| 016 | 7 | |a 1151897477 |2 DE-101 | |
| 020 | |a 9783110566161 |c pbk. |9 978-3-11-056616-1 | ||
| 035 | |a (OCoLC)1135452370 | ||
| 035 | |a (DE-599)DNB1151897477 | ||
| 040 | |a DE-604 |b ger |e rda | ||
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| 084 | |a CHE 825 |2 stub | ||
| 084 | |a CHE 820 |2 stub | ||
| 100 | 1 | |a Backman, Lars |e Verfasser |0 (DE-588)1203574185 |4 aut | |
| 245 | 1 | 0 | |a Protein chemistry |c Lars Backman |
| 264 | 1 | |a Berlin ; Boston |b De Gruyter |c [2020] | |
| 264 | 4 | |c © 2020 | |
| 300 | |a X, 236 Seiten |b Illustrationen, Diagramme (farbig) | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 490 | 0 | |a De Gruyter graduate | |
| 650 | 0 | 7 | |a Proteine |0 (DE-588)4076388-2 |2 gnd |9 rswk-swf |
| 689 | 0 | 0 | |a Proteine |0 (DE-588)4076388-2 |D s |
| 689 | 0 | |5 DE-604 | |
| 776 | 0 | 8 | |i Erscheint auch als |n Online-Ausgabe, PDF |z 978-3-11-056618-5 |
| 776 | 0 | 8 | |i Erscheint auch als |n Online-Ausgabe, EPUB |z 978-3-11-056628-4 |
| 856 | 4 | 2 | |m DNB Datenaustausch |q application/pdf |u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=031627360&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |3 Inhaltsverzeichnis |
| 943 | 1 | |a oai:aleph.bib-bvb.de:BVB01-031627360 | |
Datensatz im Suchindex
| _version_ | 1809312337073537024 |
|---|---|
| adam_text |
CONTENTS
PREFACE
*
V
1
LI
1.2
1.3
1.4
1.4.1
1.4.2
1.4.3
1.4.4
1.4.5
1.4.6
1.4.7
1.4.8
1.4.9
1.5
THE
BALLPARK
WHERE
IT
ALL
OCCURS
*
1
THE
TREE
OF
LIFE
*
2
BACTERIA
*
3
ARCHAEA
*
4
EUKARYOTES
*
4
NUCLEUS
*
4
ENDOPLASMATIC
RETICULUM
*
4
GOLGI
APPARATUS
-----
5
MITOCHONDRIA
*
6
LYSOSOME
*
7
PEROXISOME
*
7
CHLOROPLAST
*
7
VACUOL
*
9
CYTOPLASM,
CYTOSOL
AND
CYTOSKELETON
*
9
WATER
*
9
FURTHER
READING
-----
12
2
2.1
2.2
2.3
2.3.1
2.3.2
2.3.3
2.4
2.5
THE
RULES
*
13
THE
HYDROPHOBIC
EFFECT
*
13
COVALENT
BONDS
*
13
NONCOVALENT
BONDS
*
14
ION-ION
INTERACTIONS
*
15
HYDROGEN
BONDS
*
15
VAN
DER
WAALS
INTERACTIONS
*
17
PH
*
18
NUMBERS
ARE
IMPORTANT
*
18
FURTHER
READING
*
19
3
3.1
3.1.1
3.1.2
3.1.3
3.1.4
3.1.5
THE
PLAYERS
*
21
TWENTY
DIFFERENT
A-AMINO
ACIDS
*
23
NONPOLAR
AMINO
ACIDS
*
24
POLAR-UNCHARGED
AMINO
ACIDS
26
POLAR-CHARGED
AMINO
ACIDS
-----
27
AROMATIC
AMINO
ACIDS
-----
29
SUBSTITUTES
*
30
FURTHER
READING
*
32
VIII
*
CONTENTS
4
4.1
4.2
4.3
4.4
4.4.1
4.4.2
4.4.3
4.5
4.6
4.7
THE
TEAM
*
33
THE
PEPTIDE
BOND
-----
33
THE
RAMACHANDRAN
GRAPH
*
36
THE
PRIMARY
STRUCTURE
-----
37
THE
SECONDARY
STRUCTURE
*
39
CR-HELIX
-----
39
^-STRANDS
AND
P-
SHEET
*
43
TURNS
AND
LOOPS
*
46
SECONDARY
STRUCTURE
PREDICTION
*
48
THE
TERTIARY
STRUCTURE
*
48
THE
QUATERNARY
STRUCTURE
*
51
FURTHER
READING
*
52
5
5.1
5.2
5.2.1
5.2.2
5.3
5.4
5.5
THE
LEAGUE
*
53
MORE
WATER
*
54
DOMAINS
-----
55
HOW
TO
ACQUIRE
A
DOMAIN
*
59
CLASSIFYING
DOMAINS
*
61
MOTIFS
*
64
TOPOLOGY
AND
CONNECTIVITY
*
66
WHY
SHOULD
PROTEINS
BE
GROUPED?
-----
70
FURTHER
READING
-----
71
6
6.1
6.2
6.2.1
6.2.2
6.2.3
6.2.4
6.2.5
6.2.6
EL
CLASICO
*
73
MYOGLOBIN
*
73
HEMOGLOBIN
-----
75
THE
ROLE
OF
HEME
*
77
THE
BOHR
EFFECT
-----
78
2,3-BISPHOSHOGLYCERATE
-----
81
FETAL
HEMOGLOBIN
*
82
SICKLE-CELL
DISEASES
AND
SICKLE-CELL
ANEMIA
*
82
ALLOSTERY
AND
COOPERATIVE
BINDING
-----83
FURTHER
READING
-----
85
7
7.1
7.2
7.3
7.4
7.5
7.6
THE
BALL
IS
ROUND
*
87
COLLAGEN
*
87
FIBROIN
-
A
VALUABLE
PROTEIN
*
90
COILED
COIL
AND
HELICAL
BUNDLES
*
93
FIBROUS
STRUCTURES
-----96
MICROTUBULES
-----99
ACTIN
FILAMENTS
*
103
FURTHER
READING
-----
109
CONTENTS
*
IX
8
THE
MIDFIELD
*
111
8.1
LIPID
BILAYERS
*
111
8.2
MEMBRANE
PROTEINS
*
113
8.3
GLYCOPHORIN
*
114
8.4
THE
FLUID
MOSAIC
MEMBRANE
MODEL
*
117
8.5
INTEGRAL
MEMBRANE
PROTEINS
*
119
8.6
THE
HYDROPATHY
INDEX
*
122
8.7
THE
SIGNAL
PEPTIDE
*
123
FURTHER
READING
*
125
9
THE
PLAYMAKER
*
127
9.1
A
LITTLE
BIT
OF
THERMODYNAMICS
*
127
9.2
THE
BIOLOGICAL
WORKHORSE
*
129
9.3
REACTION
RATE
*
130
9.4
THE
STEADY-STATE
ASSUMPTION
*
131
9.5
THE
MICHAELIS-MENTEN
CONSTANT
*
134
9.6
THE
ACTIVE
SITE
*
137
9.7
LYSOZYME
-----
138
9.8
SERINE
PROTEASES
*
141
9.9
ENZYME
CONTROL
*
145
9.9.1
FEEDBACK
INHIBITION
*
149
9.9.2
ALLOSTER
CONTROL
*
149
9.9.3
COVALENT
MODIFICATION
*
150
9.9.4
PROTEOLYTIC
CONTROL
-----
152
9.9.5
REGULATORY
PROTEINS
*
155
9.9.6
SYNTHESIS
CONTROL
-----
157
9.10
ENZYME
CLASSES
*
157
FURTHER
READING
*
159
10
THE
STRIKER
*
161
10.1
LEVINTHAL
*
S
PARADOX
*
161
10.2
THE
ENERGY
LANDSCAPE
THEORY
AND
FOLDONS
-----
162
10.3
WHY
DO
PROTEINS
FOLD?
*
164
10.4
IN
VIVO
FOLDING
-----
165
10.5
PROTEINS
WITH
TWO
DISTINCT
STRUCTURES
*
167
10.6
INTRINSIC
DISORDERED
PROTEINS
*
168
10.7
MOONLIGHTING
-----
169
FURTHER
READING
-----
172
11
FULL-TIME
*
173
11.1
ROTARY
MOTORS
*
173
11.1.1
BACTERIAL
FLAGELLAR
MOTOR
*
177
X
*
-
CONTENTS
11.2
MUSCLE
CONTRACTION
------
178
11.2.1
MYOSIN
-----
179
11.2.2
THE
MOTOR
DOMAIN
*
180
11.2.3
THE
CROSS-BRIDGE
CYCLE
*
182
11.2.4
ROLE
OF
CALCIUM
IONS
IN
SKELETAL
MUSCLE
CONTRACTION
-----
183
11.2.5
MYOSIN
DOMAIN
ARCHITECTURE
-----
183
11.2.6
MYOSIN-DEPENDENT
CARGO
TRANSPORT
-----
186
11.3
TRANSPORT
ALONG
MICROTUBULES
*
187
11.3.1
DYNEIN
-----
187
11.3.2
KINESIN
-----
190
11.4
NONMOTILE
P-LOOP
NTPASE
-----
197
FURTHER
READING
*
200
12
EXTRA
TIME
*
203
12.1
BUFFERS
-----
203
12.2
PREPARATION
OF
EXTRACT
*
205
12.3
SOLUBILITY
AND
PRECIPITATION
*
206
12.4
CHROMATOGRAPHY
-----
208
12.4.1
ION-EXCHANGE
CHROMATOGRAPHY
(IEX)
-----
209
12.4.2
HYDROPHOBIC
INTERACTION
CHROMATOGRAPHY
(HIC)
-----
212
12.4.3
AFFINITY
CHROMATOGRAPHY
(AC)
-----
213
12.4.4
REVERSE-PHASE
CHROMATOGRAPHY
(RFC)
-----
215
12.4.5
GEL
FILTRATION
(GF)
-----
215
12.5
PROTEIN
PURIFICATION
IN
A
NUT
SHELL
-----
217
12.6
WHERE
IS
THE
PROTEIN?
*
218
12.6.1
SODIUM
DODECYL
SULFATE
POLYACRYLAMIDE
GEL
ELECTROPHORESIS
(SDS-PAGE
-----
219
FURTHER
READING
-----
222
13
PENALTY
SHOOT-OUT
*
223
13.1
X-RAY
CRYSTALLOGRAPHY
-----
223
13.2
NUCLEAR
MAGNETIC
RESONANCE
(NMR)
SPECTROSCOPY
*
225
13.3
CRYOGENIC
ELECTRON
MICROSCOPY
(CRYO-EM)
-----
227
13.4
WHAT
DOES
THE
PROTEIN
STRUCTURE
LOOK
LIKE?
-----
227
FURTHER
READING
*
229
INDEX
*
231 |
| any_adam_object | 1 |
| author | Backman, Lars |
| author_GND | (DE-588)1203574185 |
| author_facet | Backman, Lars |
| author_role | aut |
| author_sort | Backman, Lars |
| author_variant | l b lb |
| building | Verbundindex |
| bvnumber | BV046249108 |
| classification_rvk | VK 8561 |
| classification_tum | CHE 825 CHE 820 |
| ctrlnum | (OCoLC)1135452370 (DE-599)DNB1151897477 |
| discipline | Chemie / Pharmazie Chemie |
| format | Book |
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| id | DE-604.BV046249108 |
| illustrated | Illustrated |
| indexdate | 2024-09-05T00:05:06Z |
| institution | BVB |
| isbn | 9783110566161 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-031627360 |
| oclc_num | 1135452370 |
| open_access_boolean | |
| owner | DE-19 DE-BY-UBM DE-91G DE-BY-TUM DE-29T DE-11 DE-20 DE-703 |
| owner_facet | DE-19 DE-BY-UBM DE-91G DE-BY-TUM DE-29T DE-11 DE-20 DE-703 |
| physical | X, 236 Seiten Illustrationen, Diagramme (farbig) |
| publishDate | 2020 |
| publishDateSearch | 2020 |
| publishDateSort | 2020 |
| publisher | De Gruyter |
| record_format | marc |
| series2 | De Gruyter graduate |
| spelling | Backman, Lars Verfasser (DE-588)1203574185 aut Protein chemistry Lars Backman Berlin ; Boston De Gruyter [2020] © 2020 X, 236 Seiten Illustrationen, Diagramme (farbig) txt rdacontent n rdamedia nc rdacarrier De Gruyter graduate Proteine (DE-588)4076388-2 gnd rswk-swf Proteine (DE-588)4076388-2 s DE-604 Erscheint auch als Online-Ausgabe, PDF 978-3-11-056618-5 Erscheint auch als Online-Ausgabe, EPUB 978-3-11-056628-4 DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=031627360&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Backman, Lars Protein chemistry Proteine (DE-588)4076388-2 gnd |
| subject_GND | (DE-588)4076388-2 |
| title | Protein chemistry |
| title_auth | Protein chemistry |
| title_exact_search | Protein chemistry |
| title_full | Protein chemistry Lars Backman |
| title_fullStr | Protein chemistry Lars Backman |
| title_full_unstemmed | Protein chemistry Lars Backman |
| title_short | Protein chemistry |
| title_sort | protein chemistry |
| topic | Proteine (DE-588)4076388-2 gnd |
| topic_facet | Proteine |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=031627360&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT backmanlars proteinchemistry |