Molecular Mechanisms of Neurodegenerative Diseases:
With the unprecedented identification of new mutation mechanisms in neurodegenerative diseases and the emergence of common mechanisms among diseases that were once considered unrelated, neurobiologists are poised for the development of new therapies based on high throughput screenings and a better u...
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Totowa, NJ
Humana Press
2001
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| Schriftenreihe: | Contemporary Clinical Neuroscience
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| Schlagworte: | |
| Online-Zugang: | DE-355 URL des Erstveröffentlichers |
| Zusammenfassung: | With the unprecedented identification of new mutation mechanisms in neurodegenerative diseases and the emergence of common mechanisms among diseases that were once considered unrelated, neurobiologists are poised for the development of new therapies based on high throughput screenings and a better understanding of the molecular and cellular mechanisms leading to neurodegeneration. In Molecular Mechanisms of Neurodegenerative Diseases, Marie-Francoise Chesselet, MD, PhD, and a panel of leading researchers and neurologists from industry and academia critically review the most recent advances from different yet complementary points of view. Focusing on Alzheimer's, Parkinson's, and CAG triplet repeat diseases, the authors show how studies of cellular and genetically engineered animal models have enhanced our understanding of the molecular mechanisms of neurodegenerative diseases and may lead to the development of new therapeutics. Topics include the role of Ab toxicity, glial cells, and inflammation in Alzheimer's disease; the formation of abnormal protein fragments across several diseases, the impact of dopamine and mitochondrial dysfunction on neurodegeneration; and the potential of genetics to identify the molecular mechanisms of neurodegenerative diseases. Authoritative and insightful, Molecular Mechanisms of Neurodegenerative Diseases synthesizes the novel ideas and concepts now emerging to create a fresh understanding of neurodegenerative disorders, one that promises to lead to powerful new therapies that prevent, delay the onset, slow the progression, or even cure these cruel diseases |
| Beschreibung: | 1 Online-Ressource (XIII, 410 p) |
| ISBN: | 9781592590063 |
| DOI: | 10.1007/978-1-59259-006-3 |
Internformat
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Datensatz im Suchindex
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| author | Chesselet, Marie-Françoise |
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| dewey-full | 612.8 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 612 - Human physiology |
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| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| doi_str_mv | 10.1007/978-1-59259-006-3 |
| format | Electronic eBook |
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| illustrated | Not Illustrated |
| indexdate | 2024-12-06T19:01:16Z |
| institution | BVB |
| isbn | 9781592590063 |
| language | English |
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| spelling | Chesselet, Marie-Françoise Verfasser aut Molecular Mechanisms of Neurodegenerative Diseases by Marie-Françoise Chesselet Totowa, NJ Humana Press 2001 1 Online-Ressource (XIII, 410 p) txt rdacontent c rdamedia cr rdacarrier Contemporary Clinical Neuroscience With the unprecedented identification of new mutation mechanisms in neurodegenerative diseases and the emergence of common mechanisms among diseases that were once considered unrelated, neurobiologists are poised for the development of new therapies based on high throughput screenings and a better understanding of the molecular and cellular mechanisms leading to neurodegeneration. In Molecular Mechanisms of Neurodegenerative Diseases, Marie-Francoise Chesselet, MD, PhD, and a panel of leading researchers and neurologists from industry and academia critically review the most recent advances from different yet complementary points of view. Focusing on Alzheimer's, Parkinson's, and CAG triplet repeat diseases, the authors show how studies of cellular and genetically engineered animal models have enhanced our understanding of the molecular mechanisms of neurodegenerative diseases and may lead to the development of new therapeutics. Topics include the role of Ab toxicity, glial cells, and inflammation in Alzheimer's disease; the formation of abnormal protein fragments across several diseases, the impact of dopamine and mitochondrial dysfunction on neurodegeneration; and the potential of genetics to identify the molecular mechanisms of neurodegenerative diseases. Authoritative and insightful, Molecular Mechanisms of Neurodegenerative Diseases synthesizes the novel ideas and concepts now emerging to create a fresh understanding of neurodegenerative disorders, one that promises to lead to powerful new therapies that prevent, delay the onset, slow the progression, or even cure these cruel diseases Neurosciences Molekularpathologie (DE-588)4170396-0 gnd rswk-swf Nervendegeneration (DE-588)4300182-8 gnd rswk-swf Nervendegeneration (DE-588)4300182-8 s Molekularpathologie (DE-588)4170396-0 s 1\p DE-604 Erscheint auch als Druck-Ausgabe 9781617371974 Erscheint auch als Druck-Ausgabe 9780896038042 Erscheint auch als Druck-Ausgabe 9781468496024 https://doi.org/10.1007/978-1-59259-006-3 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Chesselet, Marie-Françoise Molecular Mechanisms of Neurodegenerative Diseases Neurosciences Molekularpathologie (DE-588)4170396-0 gnd Nervendegeneration (DE-588)4300182-8 gnd |
| subject_GND | (DE-588)4170396-0 (DE-588)4300182-8 |
| title | Molecular Mechanisms of Neurodegenerative Diseases |
| title_auth | Molecular Mechanisms of Neurodegenerative Diseases |
| title_exact_search | Molecular Mechanisms of Neurodegenerative Diseases |
| title_full | Molecular Mechanisms of Neurodegenerative Diseases by Marie-Françoise Chesselet |
| title_fullStr | Molecular Mechanisms of Neurodegenerative Diseases by Marie-Françoise Chesselet |
| title_full_unstemmed | Molecular Mechanisms of Neurodegenerative Diseases by Marie-Françoise Chesselet |
| title_short | Molecular Mechanisms of Neurodegenerative Diseases |
| title_sort | molecular mechanisms of neurodegenerative diseases |
| topic | Neurosciences Molekularpathologie (DE-588)4170396-0 gnd Nervendegeneration (DE-588)4300182-8 gnd |
| topic_facet | Neurosciences Molekularpathologie Nervendegeneration |
| url | https://doi.org/10.1007/978-1-59259-006-3 |
| work_keys_str_mv | AT chesseletmariefrancoise molecularmechanismsofneurodegenerativediseases |