Mutagenesis of the Mouse Genome:
The Human Genome Project has changed our approach to biology. Sequence data are being acquired from multiple organisms at a phenomenal pace and mutagenesis is being carried out in many model organisms to discover gene functions. The mouse is the first mammal to be subjected to large-scale mutagenesi...
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Dordrecht
Springer Netherlands
2004
|
| Schriftenreihe: | Georgia Genetics Review
2 |
| Schlagworte: | |
| Online-Zugang: | UBR01 Volltext |
| Zusammenfassung: | The Human Genome Project has changed our approach to biology. Sequence data are being acquired from multiple organisms at a phenomenal pace and mutagenesis is being carried out in many model organisms to discover gene functions. The mouse is the first mammal to be subjected to large-scale mutagenesis, for its biological similarities to the human will permit key discoveries. Mutagenesis of the Mouse Genome focuses on articles relevant to mouse chemical mutagenesis, and is dedicated to the memory of the mutagenesis pioneer, William L. Russell. Monica Justice provides an overview of the history of the Human Genome Project and use of the mouse as the primary organism for the functional annotation of the mammalian genome. With special articles by Jean-Louis Guenet describing the history and development of mouse chemical mutagenesis, Liane Russell analyzing decades of data on DNA damage after chemical treatment, Steven Barthold describing how environment can affect mouse phenotypes, Miriam Meisler summarizing the power of allelic series, Molly Bogue describing the variation in mouse inbred strains, and Mark Strivens and Janan Eppig showing how informatics tools can aid in functional analysis, this book is designed to be a handbook and reference guide for mouse genetics in the post-genome era |
| Beschreibung: | 1 Online-Ressource (VI, 98 p) |
| ISBN: | 9781402050572 |
| DOI: | 10.1007/978-1-4020-5057-2 |
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| 520 | |a The Human Genome Project has changed our approach to biology. Sequence data are being acquired from multiple organisms at a phenomenal pace and mutagenesis is being carried out in many model organisms to discover gene functions. The mouse is the first mammal to be subjected to large-scale mutagenesis, for its biological similarities to the human will permit key discoveries. Mutagenesis of the Mouse Genome focuses on articles relevant to mouse chemical mutagenesis, and is dedicated to the memory of the mutagenesis pioneer, William L. Russell. Monica Justice provides an overview of the history of the Human Genome Project and use of the mouse as the primary organism for the functional annotation of the mammalian genome. With special articles by Jean-Louis Guenet describing the history and development of mouse chemical mutagenesis, Liane Russell analyzing decades of data on DNA damage after chemical treatment, Steven Barthold describing how environment can affect mouse phenotypes, Miriam Meisler summarizing the power of allelic series, Molly Bogue describing the variation in mouse inbred strains, and Mark Strivens and Janan Eppig showing how informatics tools can aid in functional analysis, this book is designed to be a handbook and reference guide for mouse genetics in the post-genome era | ||
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| discipline | Biologie |
| doi_str_mv | 10.1007/978-1-4020-5057-2 |
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| id | DE-604.BV046149220 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T08:36:35Z |
| institution | BVB |
| isbn | 9781402050572 |
| language | English |
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| series2 | Georgia Genetics Review |
| spelling | Mutagenesis of the Mouse Genome edited by Monica J. Justice, Mary Bedell Dordrecht Springer Netherlands 2004 1 Online-Ressource (VI, 98 p) txt rdacontent c rdamedia cr rdacarrier Georgia Genetics Review 2 The Human Genome Project has changed our approach to biology. Sequence data are being acquired from multiple organisms at a phenomenal pace and mutagenesis is being carried out in many model organisms to discover gene functions. The mouse is the first mammal to be subjected to large-scale mutagenesis, for its biological similarities to the human will permit key discoveries. Mutagenesis of the Mouse Genome focuses on articles relevant to mouse chemical mutagenesis, and is dedicated to the memory of the mutagenesis pioneer, William L. Russell. Monica Justice provides an overview of the history of the Human Genome Project and use of the mouse as the primary organism for the functional annotation of the mammalian genome. With special articles by Jean-Louis Guenet describing the history and development of mouse chemical mutagenesis, Liane Russell analyzing decades of data on DNA damage after chemical treatment, Steven Barthold describing how environment can affect mouse phenotypes, Miriam Meisler summarizing the power of allelic series, Molly Bogue describing the variation in mouse inbred strains, and Mark Strivens and Janan Eppig showing how informatics tools can aid in functional analysis, this book is designed to be a handbook and reference guide for mouse genetics in the post-genome era Animal Genetics and Genomics Human Genetics Cell Biology Veterinary Medicine/Veterinary Science Pharmacology/Toxicology Developmental Biology Animal genetics Human genetics Cytology Veterinary medicine Toxicology Developmental biology Justice, Monica J. edt Bedell, Mary edt Erscheint auch als Druck-Ausgabe 9789401751049 Erscheint auch als Druck-Ausgabe 9781402028755 Erscheint auch als Druck-Ausgabe 9789401751032 https://doi.org/10.1007/978-1-4020-5057-2 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Mutagenesis of the Mouse Genome Animal Genetics and Genomics Human Genetics Cell Biology Veterinary Medicine/Veterinary Science Pharmacology/Toxicology Developmental Biology Animal genetics Human genetics Cytology Veterinary medicine Toxicology Developmental biology |
| title | Mutagenesis of the Mouse Genome |
| title_auth | Mutagenesis of the Mouse Genome |
| title_exact_search | Mutagenesis of the Mouse Genome |
| title_full | Mutagenesis of the Mouse Genome edited by Monica J. Justice, Mary Bedell |
| title_fullStr | Mutagenesis of the Mouse Genome edited by Monica J. Justice, Mary Bedell |
| title_full_unstemmed | Mutagenesis of the Mouse Genome edited by Monica J. Justice, Mary Bedell |
| title_short | Mutagenesis of the Mouse Genome |
| title_sort | mutagenesis of the mouse genome |
| topic | Animal Genetics and Genomics Human Genetics Cell Biology Veterinary Medicine/Veterinary Science Pharmacology/Toxicology Developmental Biology Animal genetics Human genetics Cytology Veterinary medicine Toxicology Developmental biology |
| topic_facet | Animal Genetics and Genomics Human Genetics Cell Biology Veterinary Medicine/Veterinary Science Pharmacology/Toxicology Developmental Biology Animal genetics Human genetics Cytology Veterinary medicine Toxicology Developmental biology |
| url | https://doi.org/10.1007/978-1-4020-5057-2 |
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