The Biology and Pathology of Innate Immunity Mechanisms:
In recent years increased scientific attention has been given to immediate defense mechanisms based on non-clonal recognition of microbial components. These mechanisms constitute the innate immunity arm of the body s defense. Identification of pathogens by these mechanisms involves primarily recepto...
Gespeichert in:
Weitere Verfasser: | , |
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Format: | Elektronisch E-Book |
Sprache: | English |
Veröffentlicht: |
Boston, MA
Springer US
2002
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Schriftenreihe: | Advances in Experimental Medicine and Biology
479 |
Schlagworte: | |
Online-Zugang: | UBR01 Volltext |
Zusammenfassung: | In recent years increased scientific attention has been given to immediate defense mechanisms based on non-clonal recognition of microbial components. These mechanisms constitute the innate immunity arm of the body s defense. Identification of pathogens by these mechanisms involves primarily receptors recognizing sugar moieties of various microorganisms. Innate immunity based mechanisms are essential for the existence of multicellular organisms. They are evolutionarily conserved and designed to provide immediate protection against microbial pathogens to eradicate infection. Activation of innate immunity is crucial for transition to specific immunity and for its orientation, and to assist the specific immune response in the recognition of pathogens and their destruction. Innate immunity is regularly involved in the arrest of bacterial, mycotic, viral and parasitic infections, giving the specific immune response time to become effective. It becomes critically essential in immunocompromised patients who fail to mount specific immune responses due to congenital or acquired immunodeficiencies as a result of chemotherapy, dialysis, immunosuppressive drugs, or HIV infection. The Innate Immunity arsenal constitutes polymorphonuclear and mononuclear phagocytes, mast cells, the complement system, Natural Killer cells, antimicrobial peptides, and presumably a subset of T lymphocytes with TCRl receptors |
Beschreibung: | 1 Online-Ressource (XII, 330 p) |
ISBN: | 9780306468315 |
DOI: | 10.1007/b112037 |
Internformat
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520 | |a In recent years increased scientific attention has been given to immediate defense mechanisms based on non-clonal recognition of microbial components. These mechanisms constitute the innate immunity arm of the body s defense. Identification of pathogens by these mechanisms involves primarily receptors recognizing sugar moieties of various microorganisms. Innate immunity based mechanisms are essential for the existence of multicellular organisms. They are evolutionarily conserved and designed to provide immediate protection against microbial pathogens to eradicate infection. Activation of innate immunity is crucial for transition to specific immunity and for its orientation, and to assist the specific immune response in the recognition of pathogens and their destruction. Innate immunity is regularly involved in the arrest of bacterial, mycotic, viral and parasitic infections, giving the specific immune response time to become effective. It becomes critically essential in immunocompromised patients who fail to mount specific immune responses due to congenital or acquired immunodeficiencies as a result of chemotherapy, dialysis, immunosuppressive drugs, or HIV infection. The Innate Immunity arsenal constitutes polymorphonuclear and mononuclear phagocytes, mast cells, the complement system, Natural Killer cells, antimicrobial peptides, and presumably a subset of T lymphocytes with TCRl receptors | ||
650 | 4 | |a Immunology | |
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Datensatz im Suchindex
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any_adam_object | |
author2 | Keisari, Yona Ofek, Itzhak |
author2_role | edt edt |
author2_variant | y k yk i o io |
author_facet | Keisari, Yona Ofek, Itzhak |
building | Verbundindex |
bvnumber | BV046149218 |
collection | ZDB-2-SBL |
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dewey-full | 616.079 |
dewey-hundreds | 600 - Technology (Applied sciences) |
dewey-ones | 616 - Diseases |
dewey-raw | 616.079 |
dewey-search | 616.079 |
dewey-sort | 3616.079 |
dewey-tens | 610 - Medicine and health |
discipline | Medizin |
doi_str_mv | 10.1007/b112037 |
format | Electronic eBook |
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indexdate | 2024-07-10T08:36:35Z |
institution | BVB |
isbn | 9780306468315 |
language | English |
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spelling | The Biology and Pathology of Innate Immunity Mechanisms edited by Yona Keisari, Itzhak Ofek Boston, MA Springer US 2002 1 Online-Ressource (XII, 330 p) txt rdacontent c rdamedia cr rdacarrier Advances in Experimental Medicine and Biology 479 In recent years increased scientific attention has been given to immediate defense mechanisms based on non-clonal recognition of microbial components. These mechanisms constitute the innate immunity arm of the body s defense. Identification of pathogens by these mechanisms involves primarily receptors recognizing sugar moieties of various microorganisms. Innate immunity based mechanisms are essential for the existence of multicellular organisms. They are evolutionarily conserved and designed to provide immediate protection against microbial pathogens to eradicate infection. Activation of innate immunity is crucial for transition to specific immunity and for its orientation, and to assist the specific immune response in the recognition of pathogens and their destruction. Innate immunity is regularly involved in the arrest of bacterial, mycotic, viral and parasitic infections, giving the specific immune response time to become effective. It becomes critically essential in immunocompromised patients who fail to mount specific immune responses due to congenital or acquired immunodeficiencies as a result of chemotherapy, dialysis, immunosuppressive drugs, or HIV infection. The Innate Immunity arsenal constitutes polymorphonuclear and mononuclear phagocytes, mast cells, the complement system, Natural Killer cells, antimicrobial peptides, and presumably a subset of T lymphocytes with TCRl receptors Immunology Infectious Diseases Medical Microbiology Virology Parasitology Emerging infectious diseases Microbiology Medical virology Medical parasitology Humorale Immunität (DE-588)4160794-6 gnd rswk-swf 1\p (DE-588)1071861417 Konferenzschrift gnd-content 2\p (DE-588)1071861417 Konferenzschrift 1999 Beer Sheva gnd-content Humorale Immunität (DE-588)4160794-6 s 3\p DE-604 Keisari, Yona edt Ofek, Itzhak edt Erscheint auch als Druck-Ausgabe 9781475786477 Erscheint auch als Druck-Ausgabe 9780306464096 Erscheint auch als Druck-Ausgabe 9781475786460 https://doi.org/10.1007/b112037 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 2\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 3\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
spellingShingle | The Biology and Pathology of Innate Immunity Mechanisms Immunology Infectious Diseases Medical Microbiology Virology Parasitology Emerging infectious diseases Microbiology Medical virology Medical parasitology Humorale Immunität (DE-588)4160794-6 gnd |
subject_GND | (DE-588)4160794-6 (DE-588)1071861417 |
title | The Biology and Pathology of Innate Immunity Mechanisms |
title_auth | The Biology and Pathology of Innate Immunity Mechanisms |
title_exact_search | The Biology and Pathology of Innate Immunity Mechanisms |
title_full | The Biology and Pathology of Innate Immunity Mechanisms edited by Yona Keisari, Itzhak Ofek |
title_fullStr | The Biology and Pathology of Innate Immunity Mechanisms edited by Yona Keisari, Itzhak Ofek |
title_full_unstemmed | The Biology and Pathology of Innate Immunity Mechanisms edited by Yona Keisari, Itzhak Ofek |
title_short | The Biology and Pathology of Innate Immunity Mechanisms |
title_sort | the biology and pathology of innate immunity mechanisms |
topic | Immunology Infectious Diseases Medical Microbiology Virology Parasitology Emerging infectious diseases Microbiology Medical virology Medical parasitology Humorale Immunität (DE-588)4160794-6 gnd |
topic_facet | Immunology Infectious Diseases Medical Microbiology Virology Parasitology Emerging infectious diseases Microbiology Medical virology Medical parasitology Humorale Immunität Konferenzschrift Konferenzschrift 1999 Beer Sheva |
url | https://doi.org/10.1007/b112037 |
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