Neural Stem Cells for Brain and Spinal Cord Repair:
Although neural stem cells (NSCs) have been successfully used in animal models of various neurodegenerative diseases and of brain and spinal cord injuries, their use in studies of nervous system dysfunction is still in its infancy. In Neural Stem Cells for Brain and Spinal Cord Repair, active neuros...
Gespeichert in:
| Weitere Verfasser: | , , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Totowa, NJ
Humana Press
2003
|
| Schriftenreihe: | Contemporary Neuroscience
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| Schlagworte: | |
| Online-Zugang: | UBR01 Volltext |
| Zusammenfassung: | Although neural stem cells (NSCs) have been successfully used in animal models of various neurodegenerative diseases and of brain and spinal cord injuries, their use in studies of nervous system dysfunction is still in its infancy. In Neural Stem Cells for Brain and Spinal Cord Repair, active neuroscientists survey NSCs as potential tools for central nervous system and spinal cord repair by explaining their clinically significant fundamental properties, manipulations, and potential therapeutic paradigms. Their discussion of the fundamental biology of NSCs illustrates the signaling pathways that regulate stem cell division and differentiation, and defines the methods of NSC expansion and propagation, neuromorphogenesis, the factors determining cell fate both in vitro and in situ, and the induction of self-reparative processes within the brain. They also present strategies that may lead to fruitful clinical applications in the near future. These range from the replacement of degenerated, dysfunctional, or maldeveloped cells to the provision of factors (either produced intrinsically by the cells or induced to do so following genetic engineering) that may protect, correct, recruit, promote self-repair, or mediate the connectivity of host cells. Comprehensive and up-to-date, Neural Stem Cells for Brain and Spinal Cord Repair provides the first systematic overview of the biological properties and functional characteristics of NSCs, as well as outlining of several possible areas of medicine and therapy where these cells may soon prove extremely helpful |
| Beschreibung: | 1 Online-Ressource (XIX, 434 p. 54 illus., 53 illus. in color) |
| ISBN: | 9781592592982 |
| DOI: | 10.1007/978-1-59259-298-2 |
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| 520 | |a Although neural stem cells (NSCs) have been successfully used in animal models of various neurodegenerative diseases and of brain and spinal cord injuries, their use in studies of nervous system dysfunction is still in its infancy. In Neural Stem Cells for Brain and Spinal Cord Repair, active neuroscientists survey NSCs as potential tools for central nervous system and spinal cord repair by explaining their clinically significant fundamental properties, manipulations, and potential therapeutic paradigms. Their discussion of the fundamental biology of NSCs illustrates the signaling pathways that regulate stem cell division and differentiation, and defines the methods of NSC expansion and propagation, neuromorphogenesis, the factors determining cell fate both in vitro and in situ, and the induction of self-reparative processes within the brain. They also present strategies that may lead to fruitful clinical applications in the near future. These range from the replacement of degenerated, dysfunctional, or maldeveloped cells to the provision of factors (either produced intrinsically by the cells or induced to do so following genetic engineering) that may protect, correct, recruit, promote self-repair, or mediate the connectivity of host cells. Comprehensive and up-to-date, Neural Stem Cells for Brain and Spinal Cord Repair provides the first systematic overview of the biological properties and functional characteristics of NSCs, as well as outlining of several possible areas of medicine and therapy where these cells may soon prove extremely helpful | ||
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Datensatz im Suchindex
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| dewey-full | 612.8 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 612 - Human physiology |
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| dewey-search | 612.8 |
| dewey-sort | 3612.8 |
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| discipline | Medizin |
| doi_str_mv | 10.1007/978-1-59259-298-2 |
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| id | DE-604.BV046149197 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T08:36:35Z |
| institution | BVB |
| isbn | 9781592592982 |
| language | English |
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| spelling | Neural Stem Cells for Brain and Spinal Cord Repair edited by Tanja Zigova, Evan Y. Snyder, Paul R. Sanberg Totowa, NJ Humana Press 2003 1 Online-Ressource (XIX, 434 p. 54 illus., 53 illus. in color) txt rdacontent c rdamedia cr rdacarrier Contemporary Neuroscience Although neural stem cells (NSCs) have been successfully used in animal models of various neurodegenerative diseases and of brain and spinal cord injuries, their use in studies of nervous system dysfunction is still in its infancy. In Neural Stem Cells for Brain and Spinal Cord Repair, active neuroscientists survey NSCs as potential tools for central nervous system and spinal cord repair by explaining their clinically significant fundamental properties, manipulations, and potential therapeutic paradigms. Their discussion of the fundamental biology of NSCs illustrates the signaling pathways that regulate stem cell division and differentiation, and defines the methods of NSC expansion and propagation, neuromorphogenesis, the factors determining cell fate both in vitro and in situ, and the induction of self-reparative processes within the brain. They also present strategies that may lead to fruitful clinical applications in the near future. These range from the replacement of degenerated, dysfunctional, or maldeveloped cells to the provision of factors (either produced intrinsically by the cells or induced to do so following genetic engineering) that may protect, correct, recruit, promote self-repair, or mediate the connectivity of host cells. Comprehensive and up-to-date, Neural Stem Cells for Brain and Spinal Cord Repair provides the first systematic overview of the biological properties and functional characteristics of NSCs, as well as outlining of several possible areas of medicine and therapy where these cells may soon prove extremely helpful Neurosciences Zigova, Tanja edt Snyder, Evan Y. edt Sanberg, Paul R. edt Erscheint auch als Druck-Ausgabe 9781617372988 Erscheint auch als Druck-Ausgabe 9781468497212 Erscheint auch als Druck-Ausgabe 9781588290038 https://doi.org/10.1007/978-1-59259-298-2 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Neural Stem Cells for Brain and Spinal Cord Repair Neurosciences |
| title | Neural Stem Cells for Brain and Spinal Cord Repair |
| title_auth | Neural Stem Cells for Brain and Spinal Cord Repair |
| title_exact_search | Neural Stem Cells for Brain and Spinal Cord Repair |
| title_full | Neural Stem Cells for Brain and Spinal Cord Repair edited by Tanja Zigova, Evan Y. Snyder, Paul R. Sanberg |
| title_fullStr | Neural Stem Cells for Brain and Spinal Cord Repair edited by Tanja Zigova, Evan Y. Snyder, Paul R. Sanberg |
| title_full_unstemmed | Neural Stem Cells for Brain and Spinal Cord Repair edited by Tanja Zigova, Evan Y. Snyder, Paul R. Sanberg |
| title_short | Neural Stem Cells for Brain and Spinal Cord Repair |
| title_sort | neural stem cells for brain and spinal cord repair |
| topic | Neurosciences |
| topic_facet | Neurosciences |
| url | https://doi.org/10.1007/978-1-59259-298-2 |
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