Mitochondrial Function and Biogenesis:
Mitochondria are complex organelles, possessing a double-membrane and even their own genome, the mtDNA. They play a pivotal role in cellular metabolism, respiration, and production of ATP essential for the normal function of all human organ systems. It is not surprising, therefore, that genetic defe...
Gespeichert in:
Format: | Elektronisch E-Book |
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Sprache: | English |
Veröffentlicht: |
Berlin, Heidelberg
Springer Berlin Heidelberg
2004
|
Schriftenreihe: | Topics in Current Genetics
8 |
Schlagworte: | |
Online-Zugang: | UBR01 URL des Erstveröffentlichers |
Zusammenfassung: | Mitochondria are complex organelles, possessing a double-membrane and even their own genome, the mtDNA. They play a pivotal role in cellular metabolism, respiration, and production of ATP essential for the normal function of all human organ systems. It is not surprising, therefore, that genetic defects of mitochondrial functions cause a wide spectrum of human diseases. This book provides the first modern and truly comprehensive coverage of the biochemistry, genetics, and pathology of mitochondria in different organisms. It particularly focuses on the recent advances in our understanding of basic mitochondrial research to the consequences of dysfunction at the molecular level. The 13 contributions written by leading researchers in the field include topics such as: mitochondrial genome evolution and mtDNA stability, mitochondrial biogenesis and protein quality control, mitochondrial morphology, assembly and function of the mitochondrial energy generation apparatus and mitochondrial metabolic pathways. These are particularly oriented to link in these various mitochondrial pathways to the clinical consequences of their dysfunctions |
Beschreibung: | 1 Online-Ressource (XVI, 333 p) |
ISBN: | 9783540408956 |
DOI: | 10.1007/b10825 |
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isbn | 9783540408956 |
language | English |
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physical | 1 Online-Ressource (XVI, 333 p) |
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spelling | Mitochondrial Function and Biogenesis Berlin, Heidelberg Springer Berlin Heidelberg 2004 1 Online-Ressource (XVI, 333 p) txt rdacontent c rdamedia cr rdacarrier Topics in Current Genetics 8 Mitochondria are complex organelles, possessing a double-membrane and even their own genome, the mtDNA. They play a pivotal role in cellular metabolism, respiration, and production of ATP essential for the normal function of all human organ systems. It is not surprising, therefore, that genetic defects of mitochondrial functions cause a wide spectrum of human diseases. This book provides the first modern and truly comprehensive coverage of the biochemistry, genetics, and pathology of mitochondria in different organisms. It particularly focuses on the recent advances in our understanding of basic mitochondrial research to the consequences of dysfunction at the molecular level. The 13 contributions written by leading researchers in the field include topics such as: mitochondrial genome evolution and mtDNA stability, mitochondrial biogenesis and protein quality control, mitochondrial morphology, assembly and function of the mitochondrial energy generation apparatus and mitochondrial metabolic pathways. These are particularly oriented to link in these various mitochondrial pathways to the clinical consequences of their dysfunctions Biochemistry, general Cell Biology Human Genetics Biochemistry Cytology Human genetics Mitochondrium (DE-588)4124939-2 gnd rswk-swf Biogenese (DE-588)4006799-3 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Mitochondrium (DE-588)4124939-2 s Biogenese (DE-588)4006799-3 s DE-604 Erscheint auch als Druck-Ausgabe 9783642059940 Erscheint auch als Druck-Ausgabe 9783540214892 Erscheint auch als Druck-Ausgabe 9783662308189 https://doi.org/10.1007/b10825 Verlag URL des Erstveröffentlichers Volltext |
spellingShingle | Mitochondrial Function and Biogenesis Biochemistry, general Cell Biology Human Genetics Biochemistry Cytology Human genetics Mitochondrium (DE-588)4124939-2 gnd Biogenese (DE-588)4006799-3 gnd |
subject_GND | (DE-588)4124939-2 (DE-588)4006799-3 (DE-588)4143413-4 |
title | Mitochondrial Function and Biogenesis |
title_auth | Mitochondrial Function and Biogenesis |
title_exact_search | Mitochondrial Function and Biogenesis |
title_full | Mitochondrial Function and Biogenesis |
title_fullStr | Mitochondrial Function and Biogenesis |
title_full_unstemmed | Mitochondrial Function and Biogenesis |
title_short | Mitochondrial Function and Biogenesis |
title_sort | mitochondrial function and biogenesis |
topic | Biochemistry, general Cell Biology Human Genetics Biochemistry Cytology Human genetics Mitochondrium (DE-588)4124939-2 gnd Biogenese (DE-588)4006799-3 gnd |
topic_facet | Biochemistry, general Cell Biology Human Genetics Biochemistry Cytology Human genetics Mitochondrium Biogenese Aufsatzsammlung |
url | https://doi.org/10.1007/b10825 |