Notch from Neurodevelopment to Neurodegeneration: Keeping the Fate:
Can molecular mechanisms involved in neural development help us to understand, prevent and perhaps reverse the course of brain ageing and neurodegenerative disorders? Brain development and function require complex cellular and molecular processes controlled by a number of different signaling mechani...
Gespeichert in:
| Weitere Verfasser: | , , , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Berlin, Heidelberg
Springer Berlin Heidelberg
2002
|
| Schriftenreihe: | Research and Perspectives in Alzheimer's Disease
|
| Schlagworte: | |
| Online-Zugang: | DE-355 URL des Erstveröffentlichers |
| Zusammenfassung: | Can molecular mechanisms involved in neural development help us to understand, prevent and perhaps reverse the course of brain ageing and neurodegenerative disorders? Brain development and function require complex cellular and molecular processes controlled by a number of different signaling mechanisms. One such signaling mechanism, the Notch pathway, has been recognized as an important player in the regulation of cellfate decisions during early neural development. However, the action of this evolutionary conserved and widely used cell-cell interaction mechanism is not confined to the developing nervous system. In addition, recent studies have shown that elucidating the mechanism of Notch signaling and its role in the brain is important for our understanding of neurological disorders such as Alzheimer's disease and cerebral arteriopathy CADASIL. |
| Beschreibung: | 1 Online-Ressource (XVI, 158 p) |
| ISBN: | 9783642559969 |
| DOI: | 10.1007/978-3-642-55996-9 |
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Datensatz im Suchindex
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| author2 | Christen, Yves Israël, Alain Strooper, Bart De Checler, Frédéric |
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| discipline | Medizin |
| doi_str_mv | 10.1007/978-3-642-55996-9 |
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| id | DE-604.BV046149085 |
| illustrated | Not Illustrated |
| indexdate | 2024-12-06T19:01:16Z |
| institution | BVB |
| isbn | 9783642559969 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-031529262 |
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| series2 | Research and Perspectives in Alzheimer's Disease |
| spelling | Notch from Neurodevelopment to Neurodegeneration: Keeping the Fate edited by Yves Christen, Alain Israël, Bart De Strooper, Frédéric Checler Berlin, Heidelberg Springer Berlin Heidelberg 2002 1 Online-Ressource (XVI, 158 p) txt rdacontent c rdamedia cr rdacarrier Research and Perspectives in Alzheimer's Disease Can molecular mechanisms involved in neural development help us to understand, prevent and perhaps reverse the course of brain ageing and neurodegenerative disorders? Brain development and function require complex cellular and molecular processes controlled by a number of different signaling mechanisms. One such signaling mechanism, the Notch pathway, has been recognized as an important player in the regulation of cellfate decisions during early neural development. However, the action of this evolutionary conserved and widely used cell-cell interaction mechanism is not confined to the developing nervous system. In addition, recent studies have shown that elucidating the mechanism of Notch signaling and its role in the brain is important for our understanding of neurological disorders such as Alzheimer's disease and cerebral arteriopathy CADASIL. Neurology Neurosciences Präkursor (DE-588)4300438-6 gnd rswk-swf Amyloid (DE-588)4129431-2 gnd rswk-swf Nervendegeneration (DE-588)4300182-8 gnd rswk-swf Preseniline (DE-588)4507354-5 gnd rswk-swf Signaltransduktion (DE-588)4318717-1 gnd rswk-swf Alzheimerkrankheit (DE-588)4112510-1 gnd rswk-swf (DE-588)1071861417 Konferenzschrift 2001 Paris gnd-content Alzheimerkrankheit (DE-588)4112510-1 s Amyloid (DE-588)4129431-2 s Präkursor (DE-588)4300438-6 s Signaltransduktion (DE-588)4318717-1 s DE-604 Nervendegeneration (DE-588)4300182-8 s Preseniline (DE-588)4507354-5 s Christen, Yves edt Israël, Alain edt Strooper, Bart De edt Checler, Frédéric edt Erscheint auch als Druck-Ausgabe 9783642627675 Erscheint auch als Druck-Ausgabe 9783540430735 Erscheint auch als Druck-Ausgabe 9783642559976 https://doi.org/10.1007/978-3-642-55996-9 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Notch from Neurodevelopment to Neurodegeneration: Keeping the Fate Neurology Neurosciences Präkursor (DE-588)4300438-6 gnd Amyloid (DE-588)4129431-2 gnd Nervendegeneration (DE-588)4300182-8 gnd Preseniline (DE-588)4507354-5 gnd Signaltransduktion (DE-588)4318717-1 gnd Alzheimerkrankheit (DE-588)4112510-1 gnd |
| subject_GND | (DE-588)4300438-6 (DE-588)4129431-2 (DE-588)4300182-8 (DE-588)4507354-5 (DE-588)4318717-1 (DE-588)4112510-1 (DE-588)1071861417 |
| title | Notch from Neurodevelopment to Neurodegeneration: Keeping the Fate |
| title_auth | Notch from Neurodevelopment to Neurodegeneration: Keeping the Fate |
| title_exact_search | Notch from Neurodevelopment to Neurodegeneration: Keeping the Fate |
| title_full | Notch from Neurodevelopment to Neurodegeneration: Keeping the Fate edited by Yves Christen, Alain Israël, Bart De Strooper, Frédéric Checler |
| title_fullStr | Notch from Neurodevelopment to Neurodegeneration: Keeping the Fate edited by Yves Christen, Alain Israël, Bart De Strooper, Frédéric Checler |
| title_full_unstemmed | Notch from Neurodevelopment to Neurodegeneration: Keeping the Fate edited by Yves Christen, Alain Israël, Bart De Strooper, Frédéric Checler |
| title_short | Notch from Neurodevelopment to Neurodegeneration: Keeping the Fate |
| title_sort | notch from neurodevelopment to neurodegeneration keeping the fate |
| topic | Neurology Neurosciences Präkursor (DE-588)4300438-6 gnd Amyloid (DE-588)4129431-2 gnd Nervendegeneration (DE-588)4300182-8 gnd Preseniline (DE-588)4507354-5 gnd Signaltransduktion (DE-588)4318717-1 gnd Alzheimerkrankheit (DE-588)4112510-1 gnd |
| topic_facet | Neurology Neurosciences Präkursor Amyloid Nervendegeneration Preseniline Signaltransduktion Alzheimerkrankheit Konferenzschrift 2001 Paris |
| url | https://doi.org/10.1007/978-3-642-55996-9 |
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