Peptide arrays on membrane supports: synthesis and applications
Proteins interacting with diverse ligands - proteins, peptides or DNA - are the basic principles underlying many biological processes, such as antigen-antibody binding, signal transduction or receptor binding. The technique of oligopeptide synthesis on a cellulose membrane and the subsequent binding...
Gespeichert in:
Weitere Verfasser: | , |
---|---|
Format: | Elektronisch E-Book |
Sprache: | English |
Veröffentlicht: |
Berlin, Heidelberg
Springer Berlin Heidelberg
2002
|
Schriftenreihe: | Springer Lab Manuals
|
Schlagworte: | |
Online-Zugang: | UBR01 Volltext |
Zusammenfassung: | Proteins interacting with diverse ligands - proteins, peptides or DNA - are the basic principles underlying many biological processes, such as antigen-antibody binding, signal transduction or receptor binding. The technique of oligopeptide synthesis on a cellulose membrane and the subsequent binding assays allow the investigation of protein interactions. A particular advantage of these peptide arrays (SPOT - technology) is the high number of oligopeptide probes that can be tested in parallel. Detailed protocols for peptide synthesis, and the analysis of protein-protein, protein-DNA interactions as well as epitope mapping are presented in this manual. It is ideally suited not only for basic research laboratories but also for diagnostic and therapeutic applications since many diseases are related to dysfunctions in protein recognition and binding |
Beschreibung: | 1 Online-Ressource (X, 173 p. 23 illus) |
ISBN: | 9783662092293 |
DOI: | 10.1007/978-3-662-09229-3 |
Internformat
MARC
LEADER | 00000nmm a2200000zc 4500 | ||
---|---|---|---|
001 | BV046148947 | ||
003 | DE-604 | ||
005 | 20210421 | ||
007 | cr|uuu---uuuuu | ||
008 | 190906s2002 |||| o||u| ||||||eng d | ||
020 | |a 9783662092293 |9 978-3-662-09229-3 | ||
024 | 7 | |a 10.1007/978-3-662-09229-3 |2 doi | |
035 | |a (ZDB-2-SBL)978-3-662-09229-3 | ||
035 | |a (OCoLC)1119138210 | ||
035 | |a (DE-599)BVBBV046148947 | ||
040 | |a DE-604 |b ger |e aacr | ||
041 | 0 | |a eng | |
049 | |a DE-355 | ||
082 | 0 | |a 572 |2 23 | |
084 | |a WC 4460 |0 (DE-625)148102: |2 rvk | ||
084 | |a WC 4170 |0 (DE-625)148093: |2 rvk | ||
084 | |a WD 5250 |0 (DE-625)148196: |2 rvk | ||
245 | 1 | 0 | |a Peptide arrays on membrane supports |b synthesis and applications |c edited by Joachim Koch, Michael Mahler |
264 | 1 | |a Berlin, Heidelberg |b Springer Berlin Heidelberg |c 2002 | |
300 | |a 1 Online-Ressource (X, 173 p. 23 illus) | ||
336 | |b txt |2 rdacontent | ||
337 | |b c |2 rdamedia | ||
338 | |b cr |2 rdacarrier | ||
490 | 0 | |a Springer Lab Manuals | |
520 | |a Proteins interacting with diverse ligands - proteins, peptides or DNA - are the basic principles underlying many biological processes, such as antigen-antibody binding, signal transduction or receptor binding. The technique of oligopeptide synthesis on a cellulose membrane and the subsequent binding assays allow the investigation of protein interactions. A particular advantage of these peptide arrays (SPOT - technology) is the high number of oligopeptide probes that can be tested in parallel. Detailed protocols for peptide synthesis, and the analysis of protein-protein, protein-DNA interactions as well as epitope mapping are presented in this manual. It is ideally suited not only for basic research laboratories but also for diagnostic and therapeutic applications since many diseases are related to dysfunctions in protein recognition and binding | ||
650 | 4 | |a Biochemistry, general | |
650 | 4 | |a Molecular Medicine | |
650 | 4 | |a Pharmacology/Toxicology | |
650 | 4 | |a Biochemistry | |
650 | 4 | |a Medicine | |
650 | 4 | |a Toxicology | |
650 | 0 | 7 | |a Membran |0 (DE-588)4038571-1 |2 gnd |9 rswk-swf |
650 | 0 | 7 | |a Peptide |0 (DE-588)4045125-2 |2 gnd |9 rswk-swf |
650 | 0 | 7 | |a Labortechnik |0 (DE-588)4123602-6 |2 gnd |9 rswk-swf |
650 | 0 | 7 | |a Microarray |0 (DE-588)4544227-7 |2 gnd |9 rswk-swf |
655 | 7 | |0 (DE-588)4143413-4 |a Aufsatzsammlung |2 gnd-content | |
689 | 0 | 0 | |a Membran |0 (DE-588)4038571-1 |D s |
689 | 0 | 1 | |a Peptide |0 (DE-588)4045125-2 |D s |
689 | 0 | 2 | |a Microarray |0 (DE-588)4544227-7 |D s |
689 | 0 | 3 | |a Labortechnik |0 (DE-588)4123602-6 |D s |
689 | 0 | |5 DE-604 | |
700 | 1 | |a Koch, Joachim |4 edt | |
700 | 1 | |a Mahler, Michael |4 edt | |
776 | 0 | 8 | |i Erscheint auch als |n Druck-Ausgabe |z 9783642076398 |
776 | 0 | 8 | |i Erscheint auch als |n Druck-Ausgabe |z 9783662092309 |
776 | 0 | 8 | |i Erscheint auch als |n Druck-Ausgabe |z 9783540425328 |
856 | 4 | 0 | |u https://doi.org/10.1007/978-3-662-09229-3 |x Verlag |z URL des Erstveröffentlichers |3 Volltext |
912 | |a ZDB-2-SBL | ||
940 | 1 | |q ZDB-2-SBL_2000/2004 | |
999 | |a oai:aleph.bib-bvb.de:BVB01-031529123 | ||
966 | e | |u https://doi.org/10.1007/978-3-662-09229-3 |l UBR01 |p ZDB-2-SBL |q ZDB-2-SBL_2000/2004 |x Verlag |3 Volltext |
Datensatz im Suchindex
_version_ | 1804180489866575872 |
---|---|
any_adam_object | |
author2 | Koch, Joachim Mahler, Michael |
author2_role | edt edt |
author2_variant | j k jk m m mm |
author_facet | Koch, Joachim Mahler, Michael |
building | Verbundindex |
bvnumber | BV046148947 |
classification_rvk | WC 4460 WC 4170 WD 5250 |
collection | ZDB-2-SBL |
ctrlnum | (ZDB-2-SBL)978-3-662-09229-3 (OCoLC)1119138210 (DE-599)BVBBV046148947 |
dewey-full | 572 |
dewey-hundreds | 500 - Natural sciences and mathematics |
dewey-ones | 572 - Biochemistry |
dewey-raw | 572 |
dewey-search | 572 |
dewey-sort | 3572 |
dewey-tens | 570 - Biology |
discipline | Biologie |
doi_str_mv | 10.1007/978-3-662-09229-3 |
format | Electronic eBook |
fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>03194nmm a2200637zc 4500</leader><controlfield tag="001">BV046148947</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">20210421 </controlfield><controlfield tag="007">cr|uuu---uuuuu</controlfield><controlfield tag="008">190906s2002 |||| o||u| ||||||eng d</controlfield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9783662092293</subfield><subfield code="9">978-3-662-09229-3</subfield></datafield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1007/978-3-662-09229-3</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ZDB-2-SBL)978-3-662-09229-3</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)1119138210</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV046148947</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">aacr</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-355</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">572</subfield><subfield code="2">23</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">WC 4460</subfield><subfield code="0">(DE-625)148102:</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">WC 4170</subfield><subfield code="0">(DE-625)148093:</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">WD 5250</subfield><subfield code="0">(DE-625)148196:</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Peptide arrays on membrane supports</subfield><subfield code="b">synthesis and applications</subfield><subfield code="c">edited by Joachim Koch, Michael Mahler</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Berlin, Heidelberg</subfield><subfield code="b">Springer Berlin Heidelberg</subfield><subfield code="c">2002</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 Online-Ressource (X, 173 p. 23 illus)</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="490" ind1="0" ind2=" "><subfield code="a">Springer Lab Manuals</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Proteins interacting with diverse ligands - proteins, peptides or DNA - are the basic principles underlying many biological processes, such as antigen-antibody binding, signal transduction or receptor binding. The technique of oligopeptide synthesis on a cellulose membrane and the subsequent binding assays allow the investigation of protein interactions. A particular advantage of these peptide arrays (SPOT - technology) is the high number of oligopeptide probes that can be tested in parallel. Detailed protocols for peptide synthesis, and the analysis of protein-protein, protein-DNA interactions as well as epitope mapping are presented in this manual. It is ideally suited not only for basic research laboratories but also for diagnostic and therapeutic applications since many diseases are related to dysfunctions in protein recognition and binding</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Biochemistry, general</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Molecular Medicine</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Pharmacology/Toxicology</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Biochemistry</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Medicine</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Toxicology</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Membran</subfield><subfield code="0">(DE-588)4038571-1</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Peptide</subfield><subfield code="0">(DE-588)4045125-2</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Labortechnik</subfield><subfield code="0">(DE-588)4123602-6</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Microarray</subfield><subfield code="0">(DE-588)4544227-7</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="655" ind1=" " ind2="7"><subfield code="0">(DE-588)4143413-4</subfield><subfield code="a">Aufsatzsammlung</subfield><subfield code="2">gnd-content</subfield></datafield><datafield tag="689" ind1="0" ind2="0"><subfield code="a">Membran</subfield><subfield code="0">(DE-588)4038571-1</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="1"><subfield code="a">Peptide</subfield><subfield code="0">(DE-588)4045125-2</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="2"><subfield code="a">Microarray</subfield><subfield code="0">(DE-588)4544227-7</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="3"><subfield code="a">Labortechnik</subfield><subfield code="0">(DE-588)4123602-6</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2=" "><subfield code="5">DE-604</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Koch, Joachim</subfield><subfield code="4">edt</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Mahler, Michael</subfield><subfield code="4">edt</subfield></datafield><datafield tag="776" ind1="0" ind2="8"><subfield code="i">Erscheint auch als</subfield><subfield code="n">Druck-Ausgabe</subfield><subfield code="z">9783642076398</subfield></datafield><datafield tag="776" ind1="0" ind2="8"><subfield code="i">Erscheint auch als</subfield><subfield code="n">Druck-Ausgabe</subfield><subfield code="z">9783662092309</subfield></datafield><datafield tag="776" ind1="0" ind2="8"><subfield code="i">Erscheint auch als</subfield><subfield code="n">Druck-Ausgabe</subfield><subfield code="z">9783540425328</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.1007/978-3-662-09229-3</subfield><subfield code="x">Verlag</subfield><subfield code="z">URL des Erstveröffentlichers</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-2-SBL</subfield></datafield><datafield tag="940" ind1="1" ind2=" "><subfield code="q">ZDB-2-SBL_2000/2004</subfield></datafield><datafield tag="999" ind1=" " ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-031529123</subfield></datafield><datafield tag="966" ind1="e" ind2=" "><subfield code="u">https://doi.org/10.1007/978-3-662-09229-3</subfield><subfield code="l">UBR01</subfield><subfield code="p">ZDB-2-SBL</subfield><subfield code="q">ZDB-2-SBL_2000/2004</subfield><subfield code="x">Verlag</subfield><subfield code="3">Volltext</subfield></datafield></record></collection> |
genre | (DE-588)4143413-4 Aufsatzsammlung gnd-content |
genre_facet | Aufsatzsammlung |
id | DE-604.BV046148947 |
illustrated | Not Illustrated |
indexdate | 2024-07-10T08:36:35Z |
institution | BVB |
isbn | 9783662092293 |
language | English |
oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-031529123 |
oclc_num | 1119138210 |
open_access_boolean | |
owner | DE-355 DE-BY-UBR |
owner_facet | DE-355 DE-BY-UBR |
physical | 1 Online-Ressource (X, 173 p. 23 illus) |
psigel | ZDB-2-SBL ZDB-2-SBL_2000/2004 ZDB-2-SBL ZDB-2-SBL_2000/2004 |
publishDate | 2002 |
publishDateSearch | 2002 |
publishDateSort | 2002 |
publisher | Springer Berlin Heidelberg |
record_format | marc |
series2 | Springer Lab Manuals |
spelling | Peptide arrays on membrane supports synthesis and applications edited by Joachim Koch, Michael Mahler Berlin, Heidelberg Springer Berlin Heidelberg 2002 1 Online-Ressource (X, 173 p. 23 illus) txt rdacontent c rdamedia cr rdacarrier Springer Lab Manuals Proteins interacting with diverse ligands - proteins, peptides or DNA - are the basic principles underlying many biological processes, such as antigen-antibody binding, signal transduction or receptor binding. The technique of oligopeptide synthesis on a cellulose membrane and the subsequent binding assays allow the investigation of protein interactions. A particular advantage of these peptide arrays (SPOT - technology) is the high number of oligopeptide probes that can be tested in parallel. Detailed protocols for peptide synthesis, and the analysis of protein-protein, protein-DNA interactions as well as epitope mapping are presented in this manual. It is ideally suited not only for basic research laboratories but also for diagnostic and therapeutic applications since many diseases are related to dysfunctions in protein recognition and binding Biochemistry, general Molecular Medicine Pharmacology/Toxicology Biochemistry Medicine Toxicology Membran (DE-588)4038571-1 gnd rswk-swf Peptide (DE-588)4045125-2 gnd rswk-swf Labortechnik (DE-588)4123602-6 gnd rswk-swf Microarray (DE-588)4544227-7 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Membran (DE-588)4038571-1 s Peptide (DE-588)4045125-2 s Microarray (DE-588)4544227-7 s Labortechnik (DE-588)4123602-6 s DE-604 Koch, Joachim edt Mahler, Michael edt Erscheint auch als Druck-Ausgabe 9783642076398 Erscheint auch als Druck-Ausgabe 9783662092309 Erscheint auch als Druck-Ausgabe 9783540425328 https://doi.org/10.1007/978-3-662-09229-3 Verlag URL des Erstveröffentlichers Volltext |
spellingShingle | Peptide arrays on membrane supports synthesis and applications Biochemistry, general Molecular Medicine Pharmacology/Toxicology Biochemistry Medicine Toxicology Membran (DE-588)4038571-1 gnd Peptide (DE-588)4045125-2 gnd Labortechnik (DE-588)4123602-6 gnd Microarray (DE-588)4544227-7 gnd |
subject_GND | (DE-588)4038571-1 (DE-588)4045125-2 (DE-588)4123602-6 (DE-588)4544227-7 (DE-588)4143413-4 |
title | Peptide arrays on membrane supports synthesis and applications |
title_auth | Peptide arrays on membrane supports synthesis and applications |
title_exact_search | Peptide arrays on membrane supports synthesis and applications |
title_full | Peptide arrays on membrane supports synthesis and applications edited by Joachim Koch, Michael Mahler |
title_fullStr | Peptide arrays on membrane supports synthesis and applications edited by Joachim Koch, Michael Mahler |
title_full_unstemmed | Peptide arrays on membrane supports synthesis and applications edited by Joachim Koch, Michael Mahler |
title_short | Peptide arrays on membrane supports |
title_sort | peptide arrays on membrane supports synthesis and applications |
title_sub | synthesis and applications |
topic | Biochemistry, general Molecular Medicine Pharmacology/Toxicology Biochemistry Medicine Toxicology Membran (DE-588)4038571-1 gnd Peptide (DE-588)4045125-2 gnd Labortechnik (DE-588)4123602-6 gnd Microarray (DE-588)4544227-7 gnd |
topic_facet | Biochemistry, general Molecular Medicine Pharmacology/Toxicology Biochemistry Medicine Toxicology Membran Peptide Labortechnik Microarray Aufsatzsammlung |
url | https://doi.org/10.1007/978-3-662-09229-3 |
work_keys_str_mv | AT kochjoachim peptidearraysonmembranesupportssynthesisandapplications AT mahlermichael peptidearraysonmembranesupportssynthesisandapplications |