Mitochondrial Inhibitors and Neurodegenerative Disorders:
In Mitochondrial Inhibitors and Neurodegenerative Disorders, respected investigators from around the world critically review what is known about the role of mitochondrial inhibitors in cell death and the onset of neurodegeneration. These distinguished researchers-many pioneers in the field-detail th...
Gespeichert in:
Weitere Verfasser: | , , |
---|---|
Format: | Elektronisch E-Book |
Sprache: | English |
Veröffentlicht: |
Totowa, NJ
Humana Press
2000
|
Schriftenreihe: | Contemporary Neuroscience
|
Schlagworte: | |
Online-Zugang: | DE-355 Volltext |
Zusammenfassung: | In Mitochondrial Inhibitors and Neurodegenerative Disorders, respected investigators from around the world critically review what is known about the role of mitochondrial inhibitors in cell death and the onset of neurodegeneration. These distinguished researchers-many pioneers in the field-detail the symptomatology, origin, and chemistry of mitochondrial toxins, and discuss animal models of human diseases related to abnormal mitochondrial function. The book focuses on 3-nitropropionic acid (3-NP) and its ability to replicate the cellular, anatomical, and behavioral alterations seen in Huntington's disease, and demonstrates that mitochondrial inhibitors play an important role in the etiology of central nervous system disorders. In addition, recent therapeutic modalities aimed at rescuing the central nervous system from abnormal functioning by mitochondria are discussed. With its timely, in-depth review, Mitochondrial Inhibitors and Neurodegenerative Disorders offers today's advanced investigators powerful insights into how mitochondrial toxins precipitate and exacerbate neurodegenerative disorders, and details important new treatment strategies that can halt or reverse disease progression |
Beschreibung: | 1 Online-Ressource (XVIII, 314 p. 81 illus) |
ISBN: | 9781592596928 |
DOI: | 10.1007/978-1-59259-692-8 |
Internformat
MARC
LEADER | 00000nmm a2200000zc 4500 | ||
---|---|---|---|
001 | BV046148914 | ||
003 | DE-604 | ||
007 | cr|uuu---uuuuu | ||
008 | 190906s2000 |||| o||u| ||||||eng d | ||
020 | |a 9781592596928 |9 978-1-59259-692-8 | ||
024 | 7 | |a 10.1007/978-1-59259-692-8 |2 doi | |
035 | |a (ZDB-2-SBL)978-1-59259-692-8 | ||
035 | |a (OCoLC)1119002174 | ||
035 | |a (DE-599)BVBBV046148914 | ||
040 | |a DE-604 |b ger |e aacr | ||
041 | 0 | |a eng | |
049 | |a DE-355 | ||
082 | 0 | |a 612.8 |2 23 | |
245 | 1 | 0 | |a Mitochondrial Inhibitors and Neurodegenerative Disorders |c edited by Paul R. Sanberg, Hitoo Nishino, Cesario V. Borlongan |
264 | 1 | |a Totowa, NJ |b Humana Press |c 2000 | |
300 | |a 1 Online-Ressource (XVIII, 314 p. 81 illus) | ||
336 | |b txt |2 rdacontent | ||
337 | |b c |2 rdamedia | ||
338 | |b cr |2 rdacarrier | ||
490 | 0 | |a Contemporary Neuroscience | |
520 | |a In Mitochondrial Inhibitors and Neurodegenerative Disorders, respected investigators from around the world critically review what is known about the role of mitochondrial inhibitors in cell death and the onset of neurodegeneration. These distinguished researchers-many pioneers in the field-detail the symptomatology, origin, and chemistry of mitochondrial toxins, and discuss animal models of human diseases related to abnormal mitochondrial function. The book focuses on 3-nitropropionic acid (3-NP) and its ability to replicate the cellular, anatomical, and behavioral alterations seen in Huntington's disease, and demonstrates that mitochondrial inhibitors play an important role in the etiology of central nervous system disorders. In addition, recent therapeutic modalities aimed at rescuing the central nervous system from abnormal functioning by mitochondria are discussed. With its timely, in-depth review, Mitochondrial Inhibitors and Neurodegenerative Disorders offers today's advanced investigators powerful insights into how mitochondrial toxins precipitate and exacerbate neurodegenerative disorders, and details important new treatment strategies that can halt or reverse disease progression | ||
650 | 4 | |a Neurosciences | |
650 | 4 | |a Neurosciences | |
650 | 0 | 7 | |a Mitochondriopathie |0 (DE-588)4280150-3 |2 gnd |9 rswk-swf |
650 | 0 | 7 | |a Nervensystem |0 (DE-588)4041643-4 |2 gnd |9 rswk-swf |
650 | 0 | 7 | |a Krankheit |0 (DE-588)4032844-2 |2 gnd |9 rswk-swf |
650 | 0 | 7 | |a Propionsäure |0 (DE-588)4175947-3 |2 gnd |9 rswk-swf |
650 | 0 | 7 | |a Nervengift |0 (DE-588)4171484-2 |2 gnd |9 rswk-swf |
655 | 7 | |0 (DE-588)4143413-4 |a Aufsatzsammlung |2 gnd-content | |
689 | 0 | 0 | |a Nervensystem |0 (DE-588)4041643-4 |D s |
689 | 0 | 1 | |a Krankheit |0 (DE-588)4032844-2 |D s |
689 | 0 | 2 | |a Propionsäure |0 (DE-588)4175947-3 |D s |
689 | 0 | 3 | |a Mitochondriopathie |0 (DE-588)4280150-3 |D s |
689 | 0 | |5 DE-604 | |
689 | 1 | 0 | |a Nervensystem |0 (DE-588)4041643-4 |D s |
689 | 1 | 1 | |a Krankheit |0 (DE-588)4032844-2 |D s |
689 | 1 | 2 | |a Nervengift |0 (DE-588)4171484-2 |D s |
689 | 1 | 3 | |a Mitochondriopathie |0 (DE-588)4280150-3 |D s |
689 | 1 | |5 DE-604 | |
700 | 1 | |a Sanberg, Paul R. |4 edt | |
700 | 1 | |a Nishino, Hitoo |4 edt | |
700 | 1 | |a Borlongan, Cesario V. |4 edt | |
776 | 0 | 8 | |i Erscheint auch als |n Druck-Ausgabe |z 9781468498219 |
776 | 0 | 8 | |i Erscheint auch als |n Druck-Ausgabe |z 9780896038059 |
776 | 0 | 8 | |i Erscheint auch als |n Druck-Ausgabe |z 9781468498202 |
856 | 4 | 0 | |u https://doi.org/10.1007/978-1-59259-692-8 |x Verlag |z URL des Erstveröffentlichers |3 Volltext |
912 | |a ZDB-2-SBL | ||
940 | 1 | |q ZDB-2-SBL_2000/2004 | |
943 | 1 | |a oai:aleph.bib-bvb.de:BVB01-031529091 | |
966 | e | |u https://doi.org/10.1007/978-1-59259-692-8 |l DE-355 |p ZDB-2-SBL |q ZDB-2-SBL_2000/2004 |x Verlag |3 Volltext |
Datensatz im Suchindex
_version_ | 1807322312170536960 |
---|---|
adam_text | |
any_adam_object | |
author2 | Sanberg, Paul R. Nishino, Hitoo Borlongan, Cesario V. |
author2_role | edt edt edt |
author2_variant | p r s pr prs h n hn c v b cv cvb |
author_facet | Sanberg, Paul R. Nishino, Hitoo Borlongan, Cesario V. |
building | Verbundindex |
bvnumber | BV046148914 |
collection | ZDB-2-SBL |
ctrlnum | (ZDB-2-SBL)978-1-59259-692-8 (OCoLC)1119002174 (DE-599)BVBBV046148914 |
dewey-full | 612.8 |
dewey-hundreds | 600 - Technology (Applied sciences) |
dewey-ones | 612 - Human physiology |
dewey-raw | 612.8 |
dewey-search | 612.8 |
dewey-sort | 3612.8 |
dewey-tens | 610 - Medicine and health |
discipline | Medizin |
doi_str_mv | 10.1007/978-1-59259-692-8 |
format | Electronic eBook |
fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>00000nmm a2200000zc 4500</leader><controlfield tag="001">BV046148914</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="007">cr|uuu---uuuuu</controlfield><controlfield tag="008">190906s2000 |||| o||u| ||||||eng d</controlfield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9781592596928</subfield><subfield code="9">978-1-59259-692-8</subfield></datafield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1007/978-1-59259-692-8</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ZDB-2-SBL)978-1-59259-692-8</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)1119002174</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV046148914</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">aacr</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-355</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">612.8</subfield><subfield code="2">23</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Mitochondrial Inhibitors and Neurodegenerative Disorders</subfield><subfield code="c">edited by Paul R. Sanberg, Hitoo Nishino, Cesario V. Borlongan</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Totowa, NJ</subfield><subfield code="b">Humana Press</subfield><subfield code="c">2000</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 Online-Ressource (XVIII, 314 p. 81 illus)</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="490" ind1="0" ind2=" "><subfield code="a">Contemporary Neuroscience</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">In Mitochondrial Inhibitors and Neurodegenerative Disorders, respected investigators from around the world critically review what is known about the role of mitochondrial inhibitors in cell death and the onset of neurodegeneration. These distinguished researchers-many pioneers in the field-detail the symptomatology, origin, and chemistry of mitochondrial toxins, and discuss animal models of human diseases related to abnormal mitochondrial function. The book focuses on 3-nitropropionic acid (3-NP) and its ability to replicate the cellular, anatomical, and behavioral alterations seen in Huntington's disease, and demonstrates that mitochondrial inhibitors play an important role in the etiology of central nervous system disorders. In addition, recent therapeutic modalities aimed at rescuing the central nervous system from abnormal functioning by mitochondria are discussed. With its timely, in-depth review, Mitochondrial Inhibitors and Neurodegenerative Disorders offers today's advanced investigators powerful insights into how mitochondrial toxins precipitate and exacerbate neurodegenerative disorders, and details important new treatment strategies that can halt or reverse disease progression</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Neurosciences</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Neurosciences</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Mitochondriopathie</subfield><subfield code="0">(DE-588)4280150-3</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Nervensystem</subfield><subfield code="0">(DE-588)4041643-4</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Krankheit</subfield><subfield code="0">(DE-588)4032844-2</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Propionsäure</subfield><subfield code="0">(DE-588)4175947-3</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Nervengift</subfield><subfield code="0">(DE-588)4171484-2</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="655" ind1=" " ind2="7"><subfield code="0">(DE-588)4143413-4</subfield><subfield code="a">Aufsatzsammlung</subfield><subfield code="2">gnd-content</subfield></datafield><datafield tag="689" ind1="0" ind2="0"><subfield code="a">Nervensystem</subfield><subfield code="0">(DE-588)4041643-4</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="1"><subfield code="a">Krankheit</subfield><subfield code="0">(DE-588)4032844-2</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="2"><subfield code="a">Propionsäure</subfield><subfield code="0">(DE-588)4175947-3</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="3"><subfield code="a">Mitochondriopathie</subfield><subfield code="0">(DE-588)4280150-3</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2=" "><subfield code="5">DE-604</subfield></datafield><datafield tag="689" ind1="1" ind2="0"><subfield code="a">Nervensystem</subfield><subfield code="0">(DE-588)4041643-4</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="1" ind2="1"><subfield code="a">Krankheit</subfield><subfield code="0">(DE-588)4032844-2</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="1" ind2="2"><subfield code="a">Nervengift</subfield><subfield code="0">(DE-588)4171484-2</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="1" ind2="3"><subfield code="a">Mitochondriopathie</subfield><subfield code="0">(DE-588)4280150-3</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="1" ind2=" "><subfield code="5">DE-604</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Sanberg, Paul R.</subfield><subfield code="4">edt</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Nishino, Hitoo</subfield><subfield code="4">edt</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Borlongan, Cesario V.</subfield><subfield code="4">edt</subfield></datafield><datafield tag="776" ind1="0" ind2="8"><subfield code="i">Erscheint auch als</subfield><subfield code="n">Druck-Ausgabe</subfield><subfield code="z">9781468498219</subfield></datafield><datafield tag="776" ind1="0" ind2="8"><subfield code="i">Erscheint auch als</subfield><subfield code="n">Druck-Ausgabe</subfield><subfield code="z">9780896038059</subfield></datafield><datafield tag="776" ind1="0" ind2="8"><subfield code="i">Erscheint auch als</subfield><subfield code="n">Druck-Ausgabe</subfield><subfield code="z">9781468498202</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.1007/978-1-59259-692-8</subfield><subfield code="x">Verlag</subfield><subfield code="z">URL des Erstveröffentlichers</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-2-SBL</subfield></datafield><datafield tag="940" ind1="1" ind2=" "><subfield code="q">ZDB-2-SBL_2000/2004</subfield></datafield><datafield tag="943" ind1="1" ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-031529091</subfield></datafield><datafield tag="966" ind1="e" ind2=" "><subfield code="u">https://doi.org/10.1007/978-1-59259-692-8</subfield><subfield code="l">DE-355</subfield><subfield code="p">ZDB-2-SBL</subfield><subfield code="q">ZDB-2-SBL_2000/2004</subfield><subfield code="x">Verlag</subfield><subfield code="3">Volltext</subfield></datafield></record></collection> |
genre | (DE-588)4143413-4 Aufsatzsammlung gnd-content |
genre_facet | Aufsatzsammlung |
id | DE-604.BV046148914 |
illustrated | Not Illustrated |
indexdate | 2024-08-14T00:54:30Z |
institution | BVB |
isbn | 9781592596928 |
language | English |
oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-031529091 |
oclc_num | 1119002174 |
open_access_boolean | |
owner | DE-355 DE-BY-UBR |
owner_facet | DE-355 DE-BY-UBR |
physical | 1 Online-Ressource (XVIII, 314 p. 81 illus) |
psigel | ZDB-2-SBL ZDB-2-SBL_2000/2004 ZDB-2-SBL ZDB-2-SBL_2000/2004 |
publishDate | 2000 |
publishDateSearch | 2000 |
publishDateSort | 2000 |
publisher | Humana Press |
record_format | marc |
series2 | Contemporary Neuroscience |
spelling | Mitochondrial Inhibitors and Neurodegenerative Disorders edited by Paul R. Sanberg, Hitoo Nishino, Cesario V. Borlongan Totowa, NJ Humana Press 2000 1 Online-Ressource (XVIII, 314 p. 81 illus) txt rdacontent c rdamedia cr rdacarrier Contemporary Neuroscience In Mitochondrial Inhibitors and Neurodegenerative Disorders, respected investigators from around the world critically review what is known about the role of mitochondrial inhibitors in cell death and the onset of neurodegeneration. These distinguished researchers-many pioneers in the field-detail the symptomatology, origin, and chemistry of mitochondrial toxins, and discuss animal models of human diseases related to abnormal mitochondrial function. The book focuses on 3-nitropropionic acid (3-NP) and its ability to replicate the cellular, anatomical, and behavioral alterations seen in Huntington's disease, and demonstrates that mitochondrial inhibitors play an important role in the etiology of central nervous system disorders. In addition, recent therapeutic modalities aimed at rescuing the central nervous system from abnormal functioning by mitochondria are discussed. With its timely, in-depth review, Mitochondrial Inhibitors and Neurodegenerative Disorders offers today's advanced investigators powerful insights into how mitochondrial toxins precipitate and exacerbate neurodegenerative disorders, and details important new treatment strategies that can halt or reverse disease progression Neurosciences Mitochondriopathie (DE-588)4280150-3 gnd rswk-swf Nervensystem (DE-588)4041643-4 gnd rswk-swf Krankheit (DE-588)4032844-2 gnd rswk-swf Propionsäure (DE-588)4175947-3 gnd rswk-swf Nervengift (DE-588)4171484-2 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Nervensystem (DE-588)4041643-4 s Krankheit (DE-588)4032844-2 s Propionsäure (DE-588)4175947-3 s Mitochondriopathie (DE-588)4280150-3 s DE-604 Nervengift (DE-588)4171484-2 s Sanberg, Paul R. edt Nishino, Hitoo edt Borlongan, Cesario V. edt Erscheint auch als Druck-Ausgabe 9781468498219 Erscheint auch als Druck-Ausgabe 9780896038059 Erscheint auch als Druck-Ausgabe 9781468498202 https://doi.org/10.1007/978-1-59259-692-8 Verlag URL des Erstveröffentlichers Volltext |
spellingShingle | Mitochondrial Inhibitors and Neurodegenerative Disorders Neurosciences Mitochondriopathie (DE-588)4280150-3 gnd Nervensystem (DE-588)4041643-4 gnd Krankheit (DE-588)4032844-2 gnd Propionsäure (DE-588)4175947-3 gnd Nervengift (DE-588)4171484-2 gnd |
subject_GND | (DE-588)4280150-3 (DE-588)4041643-4 (DE-588)4032844-2 (DE-588)4175947-3 (DE-588)4171484-2 (DE-588)4143413-4 |
title | Mitochondrial Inhibitors and Neurodegenerative Disorders |
title_auth | Mitochondrial Inhibitors and Neurodegenerative Disorders |
title_exact_search | Mitochondrial Inhibitors and Neurodegenerative Disorders |
title_full | Mitochondrial Inhibitors and Neurodegenerative Disorders edited by Paul R. Sanberg, Hitoo Nishino, Cesario V. Borlongan |
title_fullStr | Mitochondrial Inhibitors and Neurodegenerative Disorders edited by Paul R. Sanberg, Hitoo Nishino, Cesario V. Borlongan |
title_full_unstemmed | Mitochondrial Inhibitors and Neurodegenerative Disorders edited by Paul R. Sanberg, Hitoo Nishino, Cesario V. Borlongan |
title_short | Mitochondrial Inhibitors and Neurodegenerative Disorders |
title_sort | mitochondrial inhibitors and neurodegenerative disorders |
topic | Neurosciences Mitochondriopathie (DE-588)4280150-3 gnd Nervensystem (DE-588)4041643-4 gnd Krankheit (DE-588)4032844-2 gnd Propionsäure (DE-588)4175947-3 gnd Nervengift (DE-588)4171484-2 gnd |
topic_facet | Neurosciences Mitochondriopathie Nervensystem Krankheit Propionsäure Nervengift Aufsatzsammlung |
url | https://doi.org/10.1007/978-1-59259-692-8 |
work_keys_str_mv | AT sanbergpaulr mitochondrialinhibitorsandneurodegenerativedisorders AT nishinohitoo mitochondrialinhibitorsandneurodegenerativedisorders AT borlongancesariov mitochondrialinhibitorsandneurodegenerativedisorders |