Dendritic Cells and Virus Infection:
Dendritic cells (DC) are vital to induce potent anti-viral immune responses. However, viruses have developed a large number of different escape mechanisms in order to overcome the host immune system. A prime target in this respect are DC, since they are the only antigen presenting cell able to induc...
Gespeichert in:
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| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Berlin, Heidelberg
Springer Berlin Heidelberg
2003
|
| Schriftenreihe: | Current Topics in Microbiology and Immunology
276 |
| Schlagworte: | |
| Online-Zugang: | UBR01 Volltext |
| Zusammenfassung: | Dendritic cells (DC) are vital to induce potent anti-viral immune responses. However, viruses have developed a large number of different escape mechanisms in order to overcome the host immune system. A prime target in this respect are DC, since they are the only antigen presenting cell able to induce also naive T cells. In the present CTMI-volume the interaction between several viruses, including HIV-1, SIV, EBV, measles virus, LCMV and HSV-1, with DC will be described and discussed. It will become clear to the reader that DC often play a dual role during viral infections. On the one hand they are able to mount potent antiviral immune responses, and the other hand several viruses, including HIV-1, use DC as a vector to be transferred from the periphery to the lymph nodes were they infect their prime target cells. In the second part of this volume several DC specific immune intervention strategies will be presented. This includes topics such as DC vaccination strategies in immunotherapy, viral vectors for the genetic modification of DC and cross presentation of virus infected cells by DC. |
| Beschreibung: | 1 Online-Ressource (X, 298 p) |
| ISBN: | 9783662065082 |
| DOI: | 10.1007/978-3-662-06508-2 |
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| 520 | |a Dendritic cells (DC) are vital to induce potent anti-viral immune responses. However, viruses have developed a large number of different escape mechanisms in order to overcome the host immune system. A prime target in this respect are DC, since they are the only antigen presenting cell able to induce also naive T cells. In the present CTMI-volume the interaction between several viruses, including HIV-1, SIV, EBV, measles virus, LCMV and HSV-1, with DC will be described and discussed. It will become clear to the reader that DC often play a dual role during viral infections. On the one hand they are able to mount potent antiviral immune responses, and the other hand several viruses, including HIV-1, use DC as a vector to be transferred from the periphery to the lymph nodes were they infect their prime target cells. In the second part of this volume several DC specific immune intervention strategies will be presented. This includes topics such as DC vaccination strategies in immunotherapy, viral vectors for the genetic modification of DC and cross presentation of virus infected cells by DC. | ||
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| spelling | Dendritic Cells and Virus Infection edited by Alexander Steinkasserer Berlin, Heidelberg Springer Berlin Heidelberg 2003 1 Online-Ressource (X, 298 p) txt rdacontent c rdamedia cr rdacarrier Current Topics in Microbiology and Immunology 276 Dendritic cells (DC) are vital to induce potent anti-viral immune responses. However, viruses have developed a large number of different escape mechanisms in order to overcome the host immune system. A prime target in this respect are DC, since they are the only antigen presenting cell able to induce also naive T cells. In the present CTMI-volume the interaction between several viruses, including HIV-1, SIV, EBV, measles virus, LCMV and HSV-1, with DC will be described and discussed. It will become clear to the reader that DC often play a dual role during viral infections. On the one hand they are able to mount potent antiviral immune responses, and the other hand several viruses, including HIV-1, use DC as a vector to be transferred from the periphery to the lymph nodes were they infect their prime target cells. In the second part of this volume several DC specific immune intervention strategies will be presented. This includes topics such as DC vaccination strategies in immunotherapy, viral vectors for the genetic modification of DC and cross presentation of virus infected cells by DC. Virology Medical virology Viren (DE-588)4063589-2 gnd rswk-swf Immunreaktion (DE-588)4133841-8 gnd rswk-swf Virusinfektion (DE-588)4188401-2 gnd rswk-swf Dendritische Zelle (DE-588)4313846-9 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Virusinfektion (DE-588)4188401-2 s Dendritische Zelle (DE-588)4313846-9 s Immunreaktion (DE-588)4133841-8 s DE-604 Viren (DE-588)4063589-2 s Steinkasserer, Alexander edt Erscheint auch als Druck-Ausgabe 9783642079269 Erscheint auch als Druck-Ausgabe 9783540442905 Erscheint auch als Druck-Ausgabe 9783662065099 https://doi.org/10.1007/978-3-662-06508-2 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Dendritic Cells and Virus Infection Virology Medical virology Viren (DE-588)4063589-2 gnd Immunreaktion (DE-588)4133841-8 gnd Virusinfektion (DE-588)4188401-2 gnd Dendritische Zelle (DE-588)4313846-9 gnd |
| subject_GND | (DE-588)4063589-2 (DE-588)4133841-8 (DE-588)4188401-2 (DE-588)4313846-9 (DE-588)4143413-4 |
| title | Dendritic Cells and Virus Infection |
| title_auth | Dendritic Cells and Virus Infection |
| title_exact_search | Dendritic Cells and Virus Infection |
| title_full | Dendritic Cells and Virus Infection edited by Alexander Steinkasserer |
| title_fullStr | Dendritic Cells and Virus Infection edited by Alexander Steinkasserer |
| title_full_unstemmed | Dendritic Cells and Virus Infection edited by Alexander Steinkasserer |
| title_short | Dendritic Cells and Virus Infection |
| title_sort | dendritic cells and virus infection |
| topic | Virology Medical virology Viren (DE-588)4063589-2 gnd Immunreaktion (DE-588)4133841-8 gnd Virusinfektion (DE-588)4188401-2 gnd Dendritische Zelle (DE-588)4313846-9 gnd |
| topic_facet | Virology Medical virology Viren Immunreaktion Virusinfektion Dendritische Zelle Aufsatzsammlung |
| url | https://doi.org/10.1007/978-3-662-06508-2 |
| work_keys_str_mv | AT steinkassereralexander dendriticcellsandvirusinfection |