Toll-Like Receptor Family Members and Their Ligands:
On occasion, the innate immune system is referred to as the "primitive" immune system. Perhaps this has dissuaded immu nologists from analyzing it as energetically as they have analyzed the adaptive immune system during the past two decades. But while its phylogenetic origins are indeed a...
Gespeichert in:
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| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Berlin, Heidelberg
Springer Berlin Heidelberg
2002
|
| Schriftenreihe: | Current Topics in Microbiology and Immunology
270 |
| Schlagworte: | |
| Online-Zugang: | UBR01 Volltext |
| Zusammenfassung: | On occasion, the innate immune system is referred to as the "primitive" immune system. Perhaps this has dissuaded immu nologists from analyzing it as energetically as they have analyzed the adaptive immune system during the past two decades. But while its phylogenetic origins are indeed ancient, and though it is "of the first type", there is nothing crude, nothing unsophisti cated, and nothing "inferior" about innate immunity. On the contrary, the innate immune system has had time to achieve a level of refinement that is nothing short of dazzling, and a modicum of respect is at long last due. Any immune system has two cardinal functions. It must destroy a broad range of pathogens, and it must spare the host. The adaptive immune system has applied a modular solution to these problems. Each cell of the adaptive immune system is prescreened to eliminate those that would produce untoward interactions with self; each cell is pre-programmed to recognize a foreign epitope that the host might one day encounter. Hence, the duties of each individual lymphocyte are quite circumscribed |
| Beschreibung: | 1 Online-Ressource (X, 192 p. 6 illus. in color) |
| ISBN: | 9783642594304 |
| DOI: | 10.1007/978-3-642-59430-4 |
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| 520 | |a On occasion, the innate immune system is referred to as the "primitive" immune system. Perhaps this has dissuaded immu nologists from analyzing it as energetically as they have analyzed the adaptive immune system during the past two decades. But while its phylogenetic origins are indeed ancient, and though it is "of the first type", there is nothing crude, nothing unsophisti cated, and nothing "inferior" about innate immunity. On the contrary, the innate immune system has had time to achieve a level of refinement that is nothing short of dazzling, and a modicum of respect is at long last due. Any immune system has two cardinal functions. It must destroy a broad range of pathogens, and it must spare the host. The adaptive immune system has applied a modular solution to these problems. Each cell of the adaptive immune system is prescreened to eliminate those that would produce untoward interactions with self; each cell is pre-programmed to recognize a foreign epitope that the host might one day encounter. Hence, the duties of each individual lymphocyte are quite circumscribed | ||
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| spelling | Toll-Like Receptor Family Members and Their Ligands edited by Bruce Beutler, Hermann Wagner Berlin, Heidelberg Springer Berlin Heidelberg 2002 1 Online-Ressource (X, 192 p. 6 illus. in color) txt rdacontent c rdamedia cr rdacarrier Current Topics in Microbiology and Immunology 270 On occasion, the innate immune system is referred to as the "primitive" immune system. Perhaps this has dissuaded immu nologists from analyzing it as energetically as they have analyzed the adaptive immune system during the past two decades. But while its phylogenetic origins are indeed ancient, and though it is "of the first type", there is nothing crude, nothing unsophisti cated, and nothing "inferior" about innate immunity. On the contrary, the innate immune system has had time to achieve a level of refinement that is nothing short of dazzling, and a modicum of respect is at long last due. Any immune system has two cardinal functions. It must destroy a broad range of pathogens, and it must spare the host. The adaptive immune system has applied a modular solution to these problems. Each cell of the adaptive immune system is prescreened to eliminate those that would produce untoward interactions with self; each cell is pre-programmed to recognize a foreign epitope that the host might one day encounter. Hence, the duties of each individual lymphocyte are quite circumscribed Immunology Ligand Biochemie (DE-588)4606532-5 gnd rswk-swf Immunsystem (DE-588)4026643-6 gnd rswk-swf Rezeptor (DE-588)4049722-7 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Immunsystem (DE-588)4026643-6 s Ligand Biochemie (DE-588)4606532-5 s Rezeptor (DE-588)4049722-7 s DE-604 Beutler, Bruce edt Wagner, Hermann edt Erscheint auch als Druck-Ausgabe 9783642639753 Erscheint auch als Druck-Ausgabe 9783540435600 Erscheint auch als Druck-Ausgabe 9783642594311 https://doi.org/10.1007/978-3-642-59430-4 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Toll-Like Receptor Family Members and Their Ligands Immunology Ligand Biochemie (DE-588)4606532-5 gnd Immunsystem (DE-588)4026643-6 gnd Rezeptor (DE-588)4049722-7 gnd |
| subject_GND | (DE-588)4606532-5 (DE-588)4026643-6 (DE-588)4049722-7 (DE-588)4143413-4 |
| title | Toll-Like Receptor Family Members and Their Ligands |
| title_auth | Toll-Like Receptor Family Members and Their Ligands |
| title_exact_search | Toll-Like Receptor Family Members and Their Ligands |
| title_full | Toll-Like Receptor Family Members and Their Ligands edited by Bruce Beutler, Hermann Wagner |
| title_fullStr | Toll-Like Receptor Family Members and Their Ligands edited by Bruce Beutler, Hermann Wagner |
| title_full_unstemmed | Toll-Like Receptor Family Members and Their Ligands edited by Bruce Beutler, Hermann Wagner |
| title_short | Toll-Like Receptor Family Members and Their Ligands |
| title_sort | toll like receptor family members and their ligands |
| topic | Immunology Ligand Biochemie (DE-588)4606532-5 gnd Immunsystem (DE-588)4026643-6 gnd Rezeptor (DE-588)4049722-7 gnd |
| topic_facet | Immunology Ligand Biochemie Immunsystem Rezeptor Aufsatzsammlung |
| url | https://doi.org/10.1007/978-3-642-59430-4 |
| work_keys_str_mv | AT beutlerbruce tolllikereceptorfamilymembersandtheirligands AT wagnerhermann tolllikereceptorfamilymembersandtheirligands |