Viruses and Apoptosis:
The pathogenesis of viral infections involves dynamic interactions between viruses and hosts,which can result in different outcomes including cell death, elimination of the virus or latent infection.Viruses deliver genomes and p- teins with signaling potential into target cells, resulting in growth,...
Gespeichert in:
Weitere Verfasser: | |
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Format: | Elektronisch E-Book |
Sprache: | English |
Veröffentlicht: |
Berlin, Heidelberg
Springer Berlin Heidelberg
2004
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Schriftenreihe: | Progress in Molecular and Subcellular Biology
36 |
Schlagworte: | |
Online-Zugang: | UBR01 URL des Erstveröffentlichers |
Zusammenfassung: | The pathogenesis of viral infections involves dynamic interactions between viruses and hosts,which can result in different outcomes including cell death, elimination of the virus or latent infection.Viruses deliver genomes and p- teins with signaling potential into target cells, resulting in growth, prolife- tion and apoptosis.Viral infection modi?es key cell regulatory elements involved in apoptotic pathways to successfully accomplish viral replication despite the toxicity of viral products and the immune response elicited against the virus.Also,the interplay between virus-induced apoptosis and cell survival is mediated by an accurate balance between pro-death and anti-apoptotic signals triggered by cellular and viral proteins.Hence,viral survival products causing a delay in the completion of apoptotic process can be critical in the replication and propagation of viruses. Viral control of apoptosis can be a double-edged sword.In some viral inf- tions, immune cell apoptosis will contribute to pathogenesis and determine disease evolution either by direct infection of immune cells or as a result of bystander cell apoptosis caused by viral proteins or mediators secreted from infected cells. The apoptotic mechanisms contributing to HIV pathogenesis, the functional consequences on the immune system and the effect of antiviral therapies on this process will be reviewed in depth in this Volume |
Beschreibung: | 1 Online-Ressource (XVI, 342 p. 16 illus) |
ISBN: | 9783540742647 |
DOI: | 10.1007/978-3-540-74264-7 |
Internformat
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Datensatz im Suchindex
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discipline | Biologie Medizin |
doi_str_mv | 10.1007/978-3-540-74264-7 |
format | Electronic eBook |
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spelling | Viruses and Apoptosis edited by Covadonga Alonso Berlin, Heidelberg Springer Berlin Heidelberg 2004 1 Online-Ressource (XVI, 342 p. 16 illus) txt rdacontent c rdamedia cr rdacarrier Progress in Molecular and Subcellular Biology 36 The pathogenesis of viral infections involves dynamic interactions between viruses and hosts,which can result in different outcomes including cell death, elimination of the virus or latent infection.Viruses deliver genomes and p- teins with signaling potential into target cells, resulting in growth, prolife- tion and apoptosis.Viral infection modi?es key cell regulatory elements involved in apoptotic pathways to successfully accomplish viral replication despite the toxicity of viral products and the immune response elicited against the virus.Also,the interplay between virus-induced apoptosis and cell survival is mediated by an accurate balance between pro-death and anti-apoptotic signals triggered by cellular and viral proteins.Hence,viral survival products causing a delay in the completion of apoptotic process can be critical in the replication and propagation of viruses. Viral control of apoptosis can be a double-edged sword.In some viral inf- tions, immune cell apoptosis will contribute to pathogenesis and determine disease evolution either by direct infection of immune cells or as a result of bystander cell apoptosis caused by viral proteins or mediators secreted from infected cells. The apoptotic mechanisms contributing to HIV pathogenesis, the functional consequences on the immune system and the effect of antiviral therapies on this process will be reviewed in depth in this Volume Cell Biology Cancer Research Biochemistry, general Cytology Oncology Biochemistry Virusinfektion (DE-588)4188401-2 gnd rswk-swf Apoptosis (DE-588)4291096-1 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Virusinfektion (DE-588)4188401-2 s Apoptosis (DE-588)4291096-1 s DE-604 Alonso, Covadonga edt Erscheint auch als Druck-Ausgabe 9783540742630 Erscheint auch als Druck-Ausgabe 9783540202288 Erscheint auch als Druck-Ausgabe 9783642537004 https://doi.org/10.1007/978-3-540-74264-7 Verlag URL des Erstveröffentlichers Volltext |
spellingShingle | Viruses and Apoptosis Cell Biology Cancer Research Biochemistry, general Cytology Oncology Biochemistry Virusinfektion (DE-588)4188401-2 gnd Apoptosis (DE-588)4291096-1 gnd |
subject_GND | (DE-588)4188401-2 (DE-588)4291096-1 (DE-588)4143413-4 |
title | Viruses and Apoptosis |
title_auth | Viruses and Apoptosis |
title_exact_search | Viruses and Apoptosis |
title_full | Viruses and Apoptosis edited by Covadonga Alonso |
title_fullStr | Viruses and Apoptosis edited by Covadonga Alonso |
title_full_unstemmed | Viruses and Apoptosis edited by Covadonga Alonso |
title_short | Viruses and Apoptosis |
title_sort | viruses and apoptosis |
topic | Cell Biology Cancer Research Biochemistry, general Cytology Oncology Biochemistry Virusinfektion (DE-588)4188401-2 gnd Apoptosis (DE-588)4291096-1 gnd |
topic_facet | Cell Biology Cancer Research Biochemistry, general Cytology Oncology Biochemistry Virusinfektion Apoptosis Aufsatzsammlung |
url | https://doi.org/10.1007/978-3-540-74264-7 |
work_keys_str_mv | AT alonsocovadonga virusesandapoptosis |