Artificial Nucleases:
The development of agents capable of cleaving RNA and DNA has attracted considerable attention of researchers in the last few years, because of their application in biotechnology and pharmacology. Artificial nucleases are rationally designed to imitate the active centers of natural enzymes by simple...
Gespeichert in:
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| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Berlin, Heidelberg
Springer Berlin Heidelberg
2004
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| Schriftenreihe: | Nucleic Acids and Molecular Biology
13 |
| Schlagworte: | |
| Online-Zugang: | UBR01 Volltext |
| Zusammenfassung: | The development of agents capable of cleaving RNA and DNA has attracted considerable attention of researchers in the last few years, because of their application in biotechnology and pharmacology. Artificial nucleases are rationally designed to imitate the active centers of natural enzymes by simple structures possessing minimal sets of the most important characteristics that are essential for catalysis. Being less efficient and specific than natural enzymes, the primitive mimics are smaller, more robust and able to function in a broad range of conditions. The authors of the present volume summarize the state-of-the-art in the rapidly developing field of artificial nucleases. The chapters deal with mechanisms of RNA and DNA cleavage by chemical agents and natural enzymes, development of new nucleic acid-cleaving agents, applications of artificial nucleases, and design of oligonucleotide conjugates with RNA- and DNA-cleaving agents |
| Beschreibung: | 1 Online-Ressource (XVI, 292 p) |
| ISBN: | 9783642185106 |
| DOI: | 10.1007/978-3-642-18510-6 |
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| 520 | |a The development of agents capable of cleaving RNA and DNA has attracted considerable attention of researchers in the last few years, because of their application in biotechnology and pharmacology. Artificial nucleases are rationally designed to imitate the active centers of natural enzymes by simple structures possessing minimal sets of the most important characteristics that are essential for catalysis. Being less efficient and specific than natural enzymes, the primitive mimics are smaller, more robust and able to function in a broad range of conditions. The authors of the present volume summarize the state-of-the-art in the rapidly developing field of artificial nucleases. The chapters deal with mechanisms of RNA and DNA cleavage by chemical agents and natural enzymes, development of new nucleic acid-cleaving agents, applications of artificial nucleases, and design of oligonucleotide conjugates with RNA- and DNA-cleaving agents | ||
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Datensatz im Suchindex
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| discipline | Biologie |
| doi_str_mv | 10.1007/978-3-642-18510-6 |
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| isbn | 9783642185106 |
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| spelling | Artificial Nucleases edited by Marina A. Zenkova Berlin, Heidelberg Springer Berlin Heidelberg 2004 1 Online-Ressource (XVI, 292 p) txt rdacontent c rdamedia cr rdacarrier Nucleic Acids and Molecular Biology 13 The development of agents capable of cleaving RNA and DNA has attracted considerable attention of researchers in the last few years, because of their application in biotechnology and pharmacology. Artificial nucleases are rationally designed to imitate the active centers of natural enzymes by simple structures possessing minimal sets of the most important characteristics that are essential for catalysis. Being less efficient and specific than natural enzymes, the primitive mimics are smaller, more robust and able to function in a broad range of conditions. The authors of the present volume summarize the state-of-the-art in the rapidly developing field of artificial nucleases. The chapters deal with mechanisms of RNA and DNA cleavage by chemical agents and natural enzymes, development of new nucleic acid-cleaving agents, applications of artificial nucleases, and design of oligonucleotide conjugates with RNA- and DNA-cleaving agents Enzymology Biochemistry, general Pharmacology/Toxicology Biochemical Engineering Enzymes Biochemistry Toxicology Biochemical engineering Nucleasen (DE-588)4172116-0 gnd rswk-swf Biomimetikum (DE-588)4589414-0 gnd rswk-swf Aktives Zentrum (DE-588)4337771-3 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Nucleasen (DE-588)4172116-0 s Aktives Zentrum (DE-588)4337771-3 s Biomimetikum (DE-588)4589414-0 s DE-604 Zenkova, Marina A. edt Erscheint auch als Druck-Ausgabe 9783642621390 Erscheint auch als Druck-Ausgabe 9783540201120 Erscheint auch als Druck-Ausgabe 9783642185113 https://doi.org/10.1007/978-3-642-18510-6 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Artificial Nucleases Enzymology Biochemistry, general Pharmacology/Toxicology Biochemical Engineering Enzymes Biochemistry Toxicology Biochemical engineering Nucleasen (DE-588)4172116-0 gnd Biomimetikum (DE-588)4589414-0 gnd Aktives Zentrum (DE-588)4337771-3 gnd |
| subject_GND | (DE-588)4172116-0 (DE-588)4589414-0 (DE-588)4337771-3 (DE-588)4143413-4 |
| title | Artificial Nucleases |
| title_auth | Artificial Nucleases |
| title_exact_search | Artificial Nucleases |
| title_full | Artificial Nucleases edited by Marina A. Zenkova |
| title_fullStr | Artificial Nucleases edited by Marina A. Zenkova |
| title_full_unstemmed | Artificial Nucleases edited by Marina A. Zenkova |
| title_short | Artificial Nucleases |
| title_sort | artificial nucleases |
| topic | Enzymology Biochemistry, general Pharmacology/Toxicology Biochemical Engineering Enzymes Biochemistry Toxicology Biochemical engineering Nucleasen (DE-588)4172116-0 gnd Biomimetikum (DE-588)4589414-0 gnd Aktives Zentrum (DE-588)4337771-3 gnd |
| topic_facet | Enzymology Biochemistry, general Pharmacology/Toxicology Biochemical Engineering Enzymes Biochemistry Toxicology Biochemical engineering Nucleasen Biomimetikum Aktives Zentrum Aufsatzsammlung |
| url | https://doi.org/10.1007/978-3-642-18510-6 |
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