Rational Design of Stable Protein Formulations: Theory and Practice

Recombinant proteins and polypeptides continue to be the most important class of biotechnology-derived agents in today's pharmaceutical industry. Over the past few years, our fundamental understanding of how proteins degrade and how stabilizing agents work has made it possible to approach formu...

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Weitere Verfasser: Carpenter, John F. (HerausgeberIn), Manning, Mark C. (HerausgeberIn)
Format: Elektronisch E-Book
Sprache:English
Veröffentlicht: Boston, MA Springer US 2002
Schriftenreihe:Pharmaceutical Biotechnology 13
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Online-Zugang:UBR01
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Zusammenfassung:Recombinant proteins and polypeptides continue to be the most important class of biotechnology-derived agents in today's pharmaceutical industry. Over the past few years, our fundamental understanding of how proteins degrade and how stabilizing agents work has made it possible to approach formulation of protein pharmaceuticals from a much more rational point of view. This book describes the current level of understanding of protein instability and the strategies for stabilizing proteins under a variety of stressful conditions
Beschreibung:1 Online-Ressource (XVII, 206 p)
ISBN:9781461505570
DOI:10.1007/978-1-4615-0557-0

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