Hepatitis Prevention and Treatment:
Chronic viral hepatitis has emerged as one of the most common causes of disease and death worldwide. Because of their unique modes of replication and intimate association with the host immune system, hepatitis B virus (HBV) and hepatitis C virus (HCV) pose challenging problems to scientists in basic...
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Basel
Birkhäuser Basel
2004
|
| Schriftenreihe: | Milestones in Drug Therapy
|
| Schlagworte: | |
| Online-Zugang: | UBR01 Volltext |
| Zusammenfassung: | Chronic viral hepatitis has emerged as one of the most common causes of disease and death worldwide. Because of their unique modes of replication and intimate association with the host immune system, hepatitis B virus (HBV) and hepatitis C virus (HCV) pose challenging problems to scientists in basic and applied research as well as to clinicians engaged in disease management. Although approved antiviral therapy is available for chronic HBV, the emergence of viral resistance provides a rationale for the development of novel chemotherapeutic agents. The lack of a robust cell culture system for HCV replication and a readily accessible small-animal model of HCV infection have hampered the development of antiviral agents for HCV. Neverthe-less, new antiviral agents targeting HCV are now in preclinical and clinical development. This monograph, providing an up-to-date overview of the field of Hepatitis Prevention and Treatment, includes contributions from internationally recognized experts in the field of viral hepatitis, and covers the current state of knowledge and practice regarding the molecular biology, immunology, biochemistry, pharmacology and clinical aspects of chronic HBV and HCV infection. The volume includes salient topics such as: the history and epidemiology of HBV and HCV; recent insights into the molecular mechanisms of viral replication; the host immune response to infection and a discussion of the use (HBV) or potential development (HCV) of vaccines; the current standard of care for chronically-infected patients; and emerging therapies and issues associated with current antiviral treatments. The latest information to researchers and clinicians actively engaged in viral hepatitis research is provided, but also sufficient background and discussion of the literature to benefit the newcomer to the field |
| Beschreibung: | 1 Online-Ressource (XI, 246 p) |
| ISBN: | 9783034879033 |
| DOI: | 10.1007/978-3-0348-7903-3 |
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| spelling | Hepatitis Prevention and Treatment edited by Joseph M. Colacino, Beverly A. Heinz Basel Birkhäuser Basel 2004 1 Online-Ressource (XI, 246 p) txt rdacontent c rdamedia cr rdacarrier Milestones in Drug Therapy Chronic viral hepatitis has emerged as one of the most common causes of disease and death worldwide. Because of their unique modes of replication and intimate association with the host immune system, hepatitis B virus (HBV) and hepatitis C virus (HCV) pose challenging problems to scientists in basic and applied research as well as to clinicians engaged in disease management. Although approved antiviral therapy is available for chronic HBV, the emergence of viral resistance provides a rationale for the development of novel chemotherapeutic agents. The lack of a robust cell culture system for HCV replication and a readily accessible small-animal model of HCV infection have hampered the development of antiviral agents for HCV. Neverthe-less, new antiviral agents targeting HCV are now in preclinical and clinical development. This monograph, providing an up-to-date overview of the field of Hepatitis Prevention and Treatment, includes contributions from internationally recognized experts in the field of viral hepatitis, and covers the current state of knowledge and practice regarding the molecular biology, immunology, biochemistry, pharmacology and clinical aspects of chronic HBV and HCV infection. The volume includes salient topics such as: the history and epidemiology of HBV and HCV; recent insights into the molecular mechanisms of viral replication; the host immune response to infection and a discussion of the use (HBV) or potential development (HCV) of vaccines; the current standard of care for chronically-infected patients; and emerging therapies and issues associated with current antiviral treatments. The latest information to researchers and clinicians actively engaged in viral hepatitis research is provided, but also sufficient background and discussion of the literature to benefit the newcomer to the field Pharmacology/Toxicology Immunology Medical Microbiology Virology Infectious Diseases Toxicology Microbiology Medical virology Emerging infectious diseases Virushepatitis (DE-588)4290453-5 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Virushepatitis (DE-588)4290453-5 s DE-604 Colacino, Joseph M. edt Heinz, Beverly A. edt Erscheint auch als Druck-Ausgabe 9783034896177 Erscheint auch als Druck-Ausgabe 9783764359560 Erscheint auch als Druck-Ausgabe 9783034879040 https://doi.org/10.1007/978-3-0348-7903-3 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Hepatitis Prevention and Treatment Pharmacology/Toxicology Immunology Medical Microbiology Virology Infectious Diseases Toxicology Microbiology Medical virology Emerging infectious diseases Virushepatitis (DE-588)4290453-5 gnd |
| subject_GND | (DE-588)4290453-5 (DE-588)4143413-4 |
| title | Hepatitis Prevention and Treatment |
| title_auth | Hepatitis Prevention and Treatment |
| title_exact_search | Hepatitis Prevention and Treatment |
| title_full | Hepatitis Prevention and Treatment edited by Joseph M. Colacino, Beverly A. Heinz |
| title_fullStr | Hepatitis Prevention and Treatment edited by Joseph M. Colacino, Beverly A. Heinz |
| title_full_unstemmed | Hepatitis Prevention and Treatment edited by Joseph M. Colacino, Beverly A. Heinz |
| title_short | Hepatitis Prevention and Treatment |
| title_sort | hepatitis prevention and treatment |
| topic | Pharmacology/Toxicology Immunology Medical Microbiology Virology Infectious Diseases Toxicology Microbiology Medical virology Emerging infectious diseases Virushepatitis (DE-588)4290453-5 gnd |
| topic_facet | Pharmacology/Toxicology Immunology Medical Microbiology Virology Infectious Diseases Toxicology Microbiology Medical virology Emerging infectious diseases Virushepatitis Aufsatzsammlung |
| url | https://doi.org/10.1007/978-3-0348-7903-3 |
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