DNA Topoisomerases in Cancer Therapy: Present and Future
In the mid 80's type I and II enzymes were found to be the intracellular targets of a number of efficacious anticancer drugs such as doxorubicin, mitoxantrone, etoposide and camptothecin as a result of a continued efforts of many investigators, especially Leroy Liu and his collaborators at John...
Gespeichert in:
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| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Boston, MA
Springer US
2003
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| Schlagworte: | |
| Online-Zugang: | UBR01 URL des Erstveröffentlichers |
| Zusammenfassung: | In the mid 80's type I and II enzymes were found to be the intracellular targets of a number of efficacious anticancer drugs such as doxorubicin, mitoxantrone, etoposide and camptothecin as a result of a continued efforts of many investigators, especially Leroy Liu and his collaborators at Johns Hopkins University. Readers will find a series of chapters written by researchers actively engaged in the expanding field of topoisomerase and their inhibitors. The series of chapters cover review articles on pharmacology and the molecular mechanism of topoisomerase I- and II-targeting anticancer drugs in mammals and in the yeast Saccharomyces cerevisiae, which has proved to be a superb model organism for studies of anticancer drugs. This volume compiles up-to-date information on the topoisomerase-targeting compounds in clinical and preclinical development as a useful and important reference book for students and researchers in the field of pharmacology, toxicology, oncology and molecular biology |
| Beschreibung: | 1 Online-Ressource (XII, 202 p) |
| ISBN: | 9781461501411 |
| DOI: | 10.1007/978-1-4615-0141-1 |
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| isbn | 9781461501411 |
| language | English |
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| spelling | DNA Topoisomerases in Cancer Therapy Present and Future edited by Toshiwo Andoh Boston, MA Springer US 2003 1 Online-Ressource (XII, 202 p) txt rdacontent c rdamedia cr rdacarrier In the mid 80's type I and II enzymes were found to be the intracellular targets of a number of efficacious anticancer drugs such as doxorubicin, mitoxantrone, etoposide and camptothecin as a result of a continued efforts of many investigators, especially Leroy Liu and his collaborators at Johns Hopkins University. Readers will find a series of chapters written by researchers actively engaged in the expanding field of topoisomerase and their inhibitors. The series of chapters cover review articles on pharmacology and the molecular mechanism of topoisomerase I- and II-targeting anticancer drugs in mammals and in the yeast Saccharomyces cerevisiae, which has proved to be a superb model organism for studies of anticancer drugs. This volume compiles up-to-date information on the topoisomerase-targeting compounds in clinical and preclinical development as a useful and important reference book for students and researchers in the field of pharmacology, toxicology, oncology and molecular biology Biochemistry, general Oncology Medical Biochemistry Biochemistry Oncology Krebs Medizin (DE-588)4073781-0 gnd rswk-swf DNS-Topoisomerasen (DE-588)4333298-5 gnd rswk-swf Krebs Medizin (DE-588)4073781-0 s DNS-Topoisomerasen (DE-588)4333298-5 s 1\p DE-604 Andoh, Toshiwo edt Erscheint auch als Druck-Ausgabe 9780306477447 Erscheint auch als Druck-Ausgabe 9781461349419 Erscheint auch als Druck-Ausgabe 9781461501428 https://doi.org/10.1007/978-1-4615-0141-1 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | DNA Topoisomerases in Cancer Therapy Present and Future Biochemistry, general Oncology Medical Biochemistry Biochemistry Oncology Krebs Medizin (DE-588)4073781-0 gnd DNS-Topoisomerasen (DE-588)4333298-5 gnd |
| subject_GND | (DE-588)4073781-0 (DE-588)4333298-5 |
| title | DNA Topoisomerases in Cancer Therapy Present and Future |
| title_auth | DNA Topoisomerases in Cancer Therapy Present and Future |
| title_exact_search | DNA Topoisomerases in Cancer Therapy Present and Future |
| title_full | DNA Topoisomerases in Cancer Therapy Present and Future edited by Toshiwo Andoh |
| title_fullStr | DNA Topoisomerases in Cancer Therapy Present and Future edited by Toshiwo Andoh |
| title_full_unstemmed | DNA Topoisomerases in Cancer Therapy Present and Future edited by Toshiwo Andoh |
| title_short | DNA Topoisomerases in Cancer Therapy |
| title_sort | dna topoisomerases in cancer therapy present and future |
| title_sub | Present and Future |
| topic | Biochemistry, general Oncology Medical Biochemistry Biochemistry Oncology Krebs Medizin (DE-588)4073781-0 gnd DNS-Topoisomerasen (DE-588)4333298-5 gnd |
| topic_facet | Biochemistry, general Oncology Medical Biochemistry Biochemistry Oncology Krebs Medizin DNS-Topoisomerasen |
| url | https://doi.org/10.1007/978-1-4615-0141-1 |
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