Myb Transcription Factors: Their Role in Growth, Differentiation and Disease:
This volume represents the first collection of articles contributed by research leaders working on the Myb family of transcriptional regulatory proteins. In more than twenty chapters the authors discuss the range of biological processes and diverse cell types in which Myb proteins operate. Although...
Gespeichert in:
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| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Dordrecht
Springer Netherlands
2004
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| Schriftenreihe: | Proteins and Cell Regulation
2 |
| Schlagworte: | |
| Online-Zugang: | UBR01 URL des Erstveröffentlichers |
| Zusammenfassung: | This volume represents the first collection of articles contributed by research leaders working on the Myb family of transcriptional regulatory proteins. In more than twenty chapters the authors discuss the range of biological processes and diverse cell types in which Myb proteins operate. Although concentrating on the three vertebrate Myb family members, homologues from lower species are also discussed because of the light they are able to shed on the evolution and function of these proteins. Individual chapters describe the involvement of Myb proteins, in particular c-Myb, in normal and diseased development and function of many tissues including haemopoietic cells, blood vessels, the gastrointestinal tract and the brain. Several chapters explore the mechanistic details of the action of Myb proteins, especially structural features, their interaction with DNA and other regulatory proteins, and the variety of genes that are regulatory targets for this group of transcription factors. This work will be of interest to those working directly in the field and also to the wider research community investigating the transcriptional regulation of development, differentiation and growth. The therapeutic potential of manipulating Myb function is also discussed making the book appealing to clinician scientists in several fields including haematology, oncology and cardiology |
| Beschreibung: | 1 Online-Ressource (XXXI, 415 p) |
| ISBN: | 9781402028694 |
| DOI: | 10.1007/978-1-4020-2869-4 |
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| 520 | |a This volume represents the first collection of articles contributed by research leaders working on the Myb family of transcriptional regulatory proteins. In more than twenty chapters the authors discuss the range of biological processes and diverse cell types in which Myb proteins operate. Although concentrating on the three vertebrate Myb family members, homologues from lower species are also discussed because of the light they are able to shed on the evolution and function of these proteins. Individual chapters describe the involvement of Myb proteins, in particular c-Myb, in normal and diseased development and function of many tissues including haemopoietic cells, blood vessels, the gastrointestinal tract and the brain. Several chapters explore the mechanistic details of the action of Myb proteins, especially structural features, their interaction with DNA and other regulatory proteins, and the variety of genes that are regulatory targets for this group of transcription factors. This work will be of interest to those working directly in the field and also to the wider research community investigating the transcriptional regulation of development, differentiation and growth. The therapeutic potential of manipulating Myb function is also discussed making the book appealing to clinician scientists in several fields including haematology, oncology and cardiology | ||
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| discipline | Medizin |
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| id | DE-604.BV046148381 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T08:36:34Z |
| institution | BVB |
| isbn | 9781402028694 |
| language | English |
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| series2 | Proteins and Cell Regulation |
| spelling | Myb Transcription Factors: Their Role in Growth, Differentiation and Disease edited by Jon Frampton Dordrecht Springer Netherlands 2004 1 Online-Ressource (XXXI, 415 p) txt rdacontent c rdamedia cr rdacarrier Proteins and Cell Regulation 2 This volume represents the first collection of articles contributed by research leaders working on the Myb family of transcriptional regulatory proteins. In more than twenty chapters the authors discuss the range of biological processes and diverse cell types in which Myb proteins operate. Although concentrating on the three vertebrate Myb family members, homologues from lower species are also discussed because of the light they are able to shed on the evolution and function of these proteins. Individual chapters describe the involvement of Myb proteins, in particular c-Myb, in normal and diseased development and function of many tissues including haemopoietic cells, blood vessels, the gastrointestinal tract and the brain. Several chapters explore the mechanistic details of the action of Myb proteins, especially structural features, their interaction with DNA and other regulatory proteins, and the variety of genes that are regulatory targets for this group of transcription factors. This work will be of interest to those working directly in the field and also to the wider research community investigating the transcriptional regulation of development, differentiation and growth. The therapeutic potential of manipulating Myb function is also discussed making the book appealing to clinician scientists in several fields including haematology, oncology and cardiology Biomedicine general Cancer Research Hematology Proteomics Cell Biology Developmental Biology Medicine Oncology Cytology Developmental biology Frampton, Jon edt Erscheint auch als Druck-Ausgabe 9789048167203 Erscheint auch als Druck-Ausgabe 9781402027796 Erscheint auch als Druck-Ausgabe 9789401751384 https://doi.org/10.1007/978-1-4020-2869-4 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Myb Transcription Factors: Their Role in Growth, Differentiation and Disease Biomedicine general Cancer Research Hematology Proteomics Cell Biology Developmental Biology Medicine Oncology Cytology Developmental biology |
| title | Myb Transcription Factors: Their Role in Growth, Differentiation and Disease |
| title_auth | Myb Transcription Factors: Their Role in Growth, Differentiation and Disease |
| title_exact_search | Myb Transcription Factors: Their Role in Growth, Differentiation and Disease |
| title_full | Myb Transcription Factors: Their Role in Growth, Differentiation and Disease edited by Jon Frampton |
| title_fullStr | Myb Transcription Factors: Their Role in Growth, Differentiation and Disease edited by Jon Frampton |
| title_full_unstemmed | Myb Transcription Factors: Their Role in Growth, Differentiation and Disease edited by Jon Frampton |
| title_short | Myb Transcription Factors: Their Role in Growth, Differentiation and Disease |
| title_sort | myb transcription factors their role in growth differentiation and disease |
| topic | Biomedicine general Cancer Research Hematology Proteomics Cell Biology Developmental Biology Medicine Oncology Cytology Developmental biology |
| topic_facet | Biomedicine general Cancer Research Hematology Proteomics Cell Biology Developmental Biology Medicine Oncology Cytology Developmental biology |
| url | https://doi.org/10.1007/978-1-4020-2869-4 |
| work_keys_str_mv | AT framptonjon mybtranscriptionfactorstheirroleingrowthdifferentiationanddisease |