Proteases and Their Inhibitors in Cancer Metastasis:
In recent years, serine proteases and matrix metalloproteinases (MMPs) have gained considerable attention in tumor biology. For most of these proteases, their expression is a reliable indication of ongoing tissue remodeling. This book provides a comprehensive evaluation of the mechanisms of action o...
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Dordrecht
Springer Netherlands
2002
|
| Schriftenreihe: | Cancer Metastasis - Biology and Treatment
4 |
| Schlagworte: | |
| Online-Zugang: | UBR01 Volltext |
| Zusammenfassung: | In recent years, serine proteases and matrix metalloproteinases (MMPs) have gained considerable attention in tumor biology. For most of these proteases, their expression is a reliable indication of ongoing tissue remodeling. This book provides a comprehensive evaluation of the mechanisms of action of proteases and their inhibitors in tumor biology. The first part provides the reader with a selective overview of the molecular biology of serine proteases, MMPs and their physiological inhibitors. The most important proteases and their physiological as well as synthetic inhibitors are evaluated in the most relevant models of experimental and human cancer. The clinical aspects are also taken into account. This volume offers an update on this challenging aspect of cancer treatment, its interest bias, and possible clinical implication |
| Beschreibung: | 1 Online-Ressource (VI, 256 p) |
| ISBN: | 9781402020087 |
| DOI: | 10.1007/1-4020-2008-2 |
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| discipline | Medizin |
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| id | DE-604.BV046148242 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T08:36:33Z |
| institution | BVB |
| isbn | 9781402020087 |
| language | English |
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| series2 | Cancer Metastasis - Biology and Treatment |
| spelling | Proteases and Their Inhibitors in Cancer Metastasis edited by Jean-Michel Foidart, Ruth J. Muschel Dordrecht Springer Netherlands 2002 1 Online-Ressource (VI, 256 p) txt rdacontent c rdamedia cr rdacarrier Cancer Metastasis - Biology and Treatment 4 In recent years, serine proteases and matrix metalloproteinases (MMPs) have gained considerable attention in tumor biology. For most of these proteases, their expression is a reliable indication of ongoing tissue remodeling. This book provides a comprehensive evaluation of the mechanisms of action of proteases and their inhibitors in tumor biology. The first part provides the reader with a selective overview of the molecular biology of serine proteases, MMPs and their physiological inhibitors. The most important proteases and their physiological as well as synthetic inhibitors are evaluated in the most relevant models of experimental and human cancer. The clinical aspects are also taken into account. This volume offers an update on this challenging aspect of cancer treatment, its interest bias, and possible clinical implication Cancer Research Oncology Oncology Proteaseinhibitor (DE-588)4130450-0 gnd rswk-swf Metastase (DE-588)4125915-4 gnd rswk-swf Proteasen (DE-588)4047521-9 gnd rswk-swf Metastase (DE-588)4125915-4 s Proteasen (DE-588)4047521-9 s DE-604 Proteaseinhibitor (DE-588)4130450-0 s Foidart, Jean-Michel edt Muschel, Ruth J. edt Erscheint auch als Druck-Ausgabe 9789048161423 Erscheint auch als Druck-Ausgabe 9781402009235 Erscheint auch als Druck-Ausgabe 9789401569507 https://doi.org/10.1007/1-4020-2008-2 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Proteases and Their Inhibitors in Cancer Metastasis Cancer Research Oncology Oncology Proteaseinhibitor (DE-588)4130450-0 gnd Metastase (DE-588)4125915-4 gnd Proteasen (DE-588)4047521-9 gnd |
| subject_GND | (DE-588)4130450-0 (DE-588)4125915-4 (DE-588)4047521-9 |
| title | Proteases and Their Inhibitors in Cancer Metastasis |
| title_auth | Proteases and Their Inhibitors in Cancer Metastasis |
| title_exact_search | Proteases and Their Inhibitors in Cancer Metastasis |
| title_full | Proteases and Their Inhibitors in Cancer Metastasis edited by Jean-Michel Foidart, Ruth J. Muschel |
| title_fullStr | Proteases and Their Inhibitors in Cancer Metastasis edited by Jean-Michel Foidart, Ruth J. Muschel |
| title_full_unstemmed | Proteases and Their Inhibitors in Cancer Metastasis edited by Jean-Michel Foidart, Ruth J. Muschel |
| title_short | Proteases and Their Inhibitors in Cancer Metastasis |
| title_sort | proteases and their inhibitors in cancer metastasis |
| topic | Cancer Research Oncology Oncology Proteaseinhibitor (DE-588)4130450-0 gnd Metastase (DE-588)4125915-4 gnd Proteasen (DE-588)4047521-9 gnd |
| topic_facet | Cancer Research Oncology Oncology Proteaseinhibitor Metastase Proteasen |
| url | https://doi.org/10.1007/1-4020-2008-2 |
| work_keys_str_mv | AT foidartjeanmichel proteasesandtheirinhibitorsincancermetastasis AT muschelruthj proteasesandtheirinhibitorsincancermetastasis |