Platinum-Based Drugs in Cancer Therapy:
In Platinum-Based Drugs in Cancer Therapy, leading international experts comprehensively review all aspects of platinum anticancer drugs and their current use in treatment, as well as examining their future therapeutic prospects. Writing from a variety of disciplines, these authorities discuss the c...
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Totowa, NJ
Humana Press
2000
|
| Schriftenreihe: | Cancer Drug Discovery and Development
|
| Schlagworte: | |
| Online-Zugang: | UBR01 URL des Erstveröffentlichers |
| Zusammenfassung: | In Platinum-Based Drugs in Cancer Therapy, leading international experts comprehensively review all aspects of platinum anticancer drugs and their current use in treatment, as well as examining their future therapeutic prospects. Writing from a variety of disciplines, these authorities discuss the chemistry of cisplatin in aqueous solution, the molecular interaction of platinum drugs with DNA, and such exciting new areas as DNA mismatch repair, replicative bypass, apoptosis, and the transport of platinum drugs into tumor cells. The antitumor activity and toxicology of platinum-based drugs is also addressed in a thorough discussion of the clinical experience with cisplatin and carboplatin, including their promising recent combinations with taxanes and oxaliplatin. The emergent platinum drugs of the future-orally active agents, the sterically hindered ZD0473, and the polynuclear charged platinum BBR3464-are also fully considered. Timely and interdisciplinary, Platinum-Based Drugs in Cancer Therapy offers cancer therapeutics specialists an illuminating survey of every aspect of platinum drugs from mechanisms of action to toxicology, tumor resistance, and new analogs. This important book captures the essence of the fresh clinical possibilities now strongly emerging thirty years after cisplatin's discovery |
| Beschreibung: | 1 Online-Ressource (XII, 341 p. 5 illus) |
| ISBN: | 9781592590124 |
| DOI: | 10.1007/978-1-59259-012-4 |
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| 520 | |a In Platinum-Based Drugs in Cancer Therapy, leading international experts comprehensively review all aspects of platinum anticancer drugs and their current use in treatment, as well as examining their future therapeutic prospects. Writing from a variety of disciplines, these authorities discuss the chemistry of cisplatin in aqueous solution, the molecular interaction of platinum drugs with DNA, and such exciting new areas as DNA mismatch repair, replicative bypass, apoptosis, and the transport of platinum drugs into tumor cells. The antitumor activity and toxicology of platinum-based drugs is also addressed in a thorough discussion of the clinical experience with cisplatin and carboplatin, including their promising recent combinations with taxanes and oxaliplatin. The emergent platinum drugs of the future-orally active agents, the sterically hindered ZD0473, and the polynuclear charged platinum BBR3464-are also fully considered. Timely and interdisciplinary, Platinum-Based Drugs in Cancer Therapy offers cancer therapeutics specialists an illuminating survey of every aspect of platinum drugs from mechanisms of action to toxicology, tumor resistance, and new analogs. This important book captures the essence of the fresh clinical possibilities now strongly emerging thirty years after cisplatin's discovery | ||
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| discipline | Medizin |
| doi_str_mv | 10.1007/978-1-59259-012-4 |
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| id | DE-604.BV046147330 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T08:36:32Z |
| institution | BVB |
| isbn | 9781592590124 |
| language | English |
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| physical | 1 Online-Ressource (XII, 341 p. 5 illus) |
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| publishDate | 2000 |
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| publisher | Humana Press |
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| series2 | Cancer Drug Discovery and Development |
| spelling | Platinum-Based Drugs in Cancer Therapy edited by Lloyd R. Kelland, Nicholas P. Farrell Totowa, NJ Humana Press 2000 1 Online-Ressource (XII, 341 p. 5 illus) txt rdacontent c rdamedia cr rdacarrier Cancer Drug Discovery and Development In Platinum-Based Drugs in Cancer Therapy, leading international experts comprehensively review all aspects of platinum anticancer drugs and their current use in treatment, as well as examining their future therapeutic prospects. Writing from a variety of disciplines, these authorities discuss the chemistry of cisplatin in aqueous solution, the molecular interaction of platinum drugs with DNA, and such exciting new areas as DNA mismatch repair, replicative bypass, apoptosis, and the transport of platinum drugs into tumor cells. The antitumor activity and toxicology of platinum-based drugs is also addressed in a thorough discussion of the clinical experience with cisplatin and carboplatin, including their promising recent combinations with taxanes and oxaliplatin. The emergent platinum drugs of the future-orally active agents, the sterically hindered ZD0473, and the polynuclear charged platinum BBR3464-are also fully considered. Timely and interdisciplinary, Platinum-Based Drugs in Cancer Therapy offers cancer therapeutics specialists an illuminating survey of every aspect of platinum drugs from mechanisms of action to toxicology, tumor resistance, and new analogs. This important book captures the essence of the fresh clinical possibilities now strongly emerging thirty years after cisplatin's discovery Oncology Oncology Kelland, Lloyd R. edt Farrell, Nicholas P. edt Erscheint auch als Druck-Ausgabe 9781617370915 Erscheint auch als Druck-Ausgabe 9780896035997 Erscheint auch als Druck-Ausgabe 9781468496048 https://doi.org/10.1007/978-1-59259-012-4 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Platinum-Based Drugs in Cancer Therapy Oncology Oncology |
| title | Platinum-Based Drugs in Cancer Therapy |
| title_auth | Platinum-Based Drugs in Cancer Therapy |
| title_exact_search | Platinum-Based Drugs in Cancer Therapy |
| title_full | Platinum-Based Drugs in Cancer Therapy edited by Lloyd R. Kelland, Nicholas P. Farrell |
| title_fullStr | Platinum-Based Drugs in Cancer Therapy edited by Lloyd R. Kelland, Nicholas P. Farrell |
| title_full_unstemmed | Platinum-Based Drugs in Cancer Therapy edited by Lloyd R. Kelland, Nicholas P. Farrell |
| title_short | Platinum-Based Drugs in Cancer Therapy |
| title_sort | platinum based drugs in cancer therapy |
| topic | Oncology Oncology |
| topic_facet | Oncology Oncology |
| url | https://doi.org/10.1007/978-1-59259-012-4 |
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