Targeting Treatment of Soft Tissue Sarcomas:
Recent achievements in the development of new techniques and agents for the treatment of cancer in general as well as for soft tissue sarcomas are tremendous. Molecular biology research has changed the landscape considerably and an increasing number of subtypes of soft tissue sarcomas are related to...
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Boston, MA
Springer US
2004
|
| Schriftenreihe: | Cancer Treatment and Research
120 |
| Schlagworte: | |
| Online-Zugang: | UBR01 Volltext |
| Zusammenfassung: | Recent achievements in the development of new techniques and agents for the treatment of cancer in general as well as for soft tissue sarcomas are tremendous. Molecular biology research has changed the landscape considerably and an increasing number of subtypes of soft tissue sarcomas are related to changes in cellular growth factors in the cell signaling pathways. This enables the development of targeted agents with specific activity against these factors. The presence of the KIT receptor at the surface of the gastrointestinal stroma tumor cell, and the activation constituted by mutations has led to the discovery of an extremely active specific KIT tyrosine kinase inhibitor. In accordance with the more targeted approach in drug use, the changes in the field of radiation therapy and surgery basically focus on a better targeting of the disease, albeit not yet based on the molecular characteristics. All of these stress the importance of the multidisciplinary approach to the treatment of soft tissue sarcoma that was the focus of previous editions of this book. Targeting Treatment of Soft Tissue Sarcomas summarizes the recent events in this field, putting the achievements in perspective. Physicians and researchers working in the field of soft tissue sarcomas must be aware of the changes in treatment, the underlying concepts, and of the changes we face in the future |
| Beschreibung: | 1 Online-Ressource (VII, 184 p) |
| ISBN: | 9781402078569 |
| DOI: | 10.1007/b113259 |
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| 520 | |a Recent achievements in the development of new techniques and agents for the treatment of cancer in general as well as for soft tissue sarcomas are tremendous. Molecular biology research has changed the landscape considerably and an increasing number of subtypes of soft tissue sarcomas are related to changes in cellular growth factors in the cell signaling pathways. This enables the development of targeted agents with specific activity against these factors. The presence of the KIT receptor at the surface of the gastrointestinal stroma tumor cell, and the activation constituted by mutations has led to the discovery of an extremely active specific KIT tyrosine kinase inhibitor. In accordance with the more targeted approach in drug use, the changes in the field of radiation therapy and surgery basically focus on a better targeting of the disease, albeit not yet based on the molecular characteristics. All of these stress the importance of the multidisciplinary approach to the treatment of soft tissue sarcoma that was the focus of previous editions of this book. Targeting Treatment of Soft Tissue Sarcomas summarizes the recent events in this field, putting the achievements in perspective. Physicians and researchers working in the field of soft tissue sarcomas must be aware of the changes in treatment, the underlying concepts, and of the changes we face in the future | ||
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| spelling | Targeting Treatment of Soft Tissue Sarcomas edited by Jaap Verweij, Herbert M. Pinedo Boston, MA Springer US 2004 1 Online-Ressource (VII, 184 p) txt rdacontent c rdamedia cr rdacarrier Cancer Treatment and Research 120 Recent achievements in the development of new techniques and agents for the treatment of cancer in general as well as for soft tissue sarcomas are tremendous. Molecular biology research has changed the landscape considerably and an increasing number of subtypes of soft tissue sarcomas are related to changes in cellular growth factors in the cell signaling pathways. This enables the development of targeted agents with specific activity against these factors. The presence of the KIT receptor at the surface of the gastrointestinal stroma tumor cell, and the activation constituted by mutations has led to the discovery of an extremely active specific KIT tyrosine kinase inhibitor. In accordance with the more targeted approach in drug use, the changes in the field of radiation therapy and surgery basically focus on a better targeting of the disease, albeit not yet based on the molecular characteristics. All of these stress the importance of the multidisciplinary approach to the treatment of soft tissue sarcoma that was the focus of previous editions of this book. Targeting Treatment of Soft Tissue Sarcomas summarizes the recent events in this field, putting the achievements in perspective. Physicians and researchers working in the field of soft tissue sarcomas must be aware of the changes in treatment, the underlying concepts, and of the changes we face in the future Cancer Research Oncology Oncology Sarkom (DE-588)4179127-7 gnd rswk-swf Cytostatikum (DE-588)4068347-3 gnd rswk-swf Targeted drug delivery (DE-588)4302415-4 gnd rswk-swf 1\p (DE-588)4143413-4 Aufsatzsammlung gnd-content Sarkom (DE-588)4179127-7 s Cytostatikum (DE-588)4068347-3 s Targeted drug delivery (DE-588)4302415-4 s 2\p DE-604 Verweij, Jaap edt Pinedo, Herbert M. edt Erscheint auch als Druck-Ausgabe 9781475779417 Erscheint auch als Druck-Ausgabe 9781402078088 Erscheint auch als Druck-Ausgabe 9781475779400 https://doi.org/10.1007/b113259 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 2\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Targeting Treatment of Soft Tissue Sarcomas Cancer Research Oncology Oncology Sarkom (DE-588)4179127-7 gnd Cytostatikum (DE-588)4068347-3 gnd Targeted drug delivery (DE-588)4302415-4 gnd |
| subject_GND | (DE-588)4179127-7 (DE-588)4068347-3 (DE-588)4302415-4 (DE-588)4143413-4 |
| title | Targeting Treatment of Soft Tissue Sarcomas |
| title_auth | Targeting Treatment of Soft Tissue Sarcomas |
| title_exact_search | Targeting Treatment of Soft Tissue Sarcomas |
| title_full | Targeting Treatment of Soft Tissue Sarcomas edited by Jaap Verweij, Herbert M. Pinedo |
| title_fullStr | Targeting Treatment of Soft Tissue Sarcomas edited by Jaap Verweij, Herbert M. Pinedo |
| title_full_unstemmed | Targeting Treatment of Soft Tissue Sarcomas edited by Jaap Verweij, Herbert M. Pinedo |
| title_short | Targeting Treatment of Soft Tissue Sarcomas |
| title_sort | targeting treatment of soft tissue sarcomas |
| topic | Cancer Research Oncology Oncology Sarkom (DE-588)4179127-7 gnd Cytostatikum (DE-588)4068347-3 gnd Targeted drug delivery (DE-588)4302415-4 gnd |
| topic_facet | Cancer Research Oncology Oncology Sarkom Cytostatikum Targeted drug delivery Aufsatzsammlung |
| url | https://doi.org/10.1007/b113259 |
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