Acute Leukemias VII: Experimental Approaches and Novel Therapies
In the last few years there has been a dramatic increase in the knowledge about the biology of acute leukemias and, in particular, of the underlying genetic and molecular events. These processes lead to the deregulation of central transcription factors and genes regulating cell proliferation and dif...
Gespeichert in:
| Weitere Verfasser: | , , , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Berlin, Heidelberg
Springer Berlin Heidelberg
1998
|
| Schriftenreihe: | Haematology and Blood Transfusion Hämatologie und Bluttransfusion
39 |
| Schlagworte: | |
| Online-Zugang: | UBR01 Volltext |
| Zusammenfassung: | In the last few years there has been a dramatic increase in the knowledge about the biology of acute leukemias and, in particular, of the underlying genetic and molecular events. These processes lead to the deregulation of central transcription factors and genes regulating cell proliferation and differentiation and ultimately determine the response to chemotherapy and the long-term prognosis of patients suffering from these disorders. The increasing insights into the biology of acute leukemias also provide the basis for new pathogenetically oriented therapeutic strategies which aim at interfering with pathologically activated gene products or augmenting the antileukemic immune response. They give also new information about the mechanisms of action of conventional treatments and, in particular, cytostatic agents and thus allow drug regimens to be optimized. In Acute Leukemia VII - Experimental Approaches and Novel Therapies these topics are updated by leading scientists and clinicians around the world. The high quality of contributions makes this book a useful state-of-the-art report for both clinical oncologists and basic scientists and provides a comprehensive overview of the most recent achievements which translate into new treatment strategies and, hence, an improved outlook for patients suffering from acute leukemias |
| Beschreibung: | 1 Online-Ressource (XXXVIII, 1202 p. 205 illus) |
| ISBN: | 9783642719608 |
| DOI: | 10.1007/978-3-642-71960-8 |
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| 520 | |a In the last few years there has been a dramatic increase in the knowledge about the biology of acute leukemias and, in particular, of the underlying genetic and molecular events. These processes lead to the deregulation of central transcription factors and genes regulating cell proliferation and differentiation and ultimately determine the response to chemotherapy and the long-term prognosis of patients suffering from these disorders. The increasing insights into the biology of acute leukemias also provide the basis for new pathogenetically oriented therapeutic strategies which aim at interfering with pathologically activated gene products or augmenting the antileukemic immune response. They give also new information about the mechanisms of action of conventional treatments and, in particular, cytostatic agents and thus allow drug regimens to be optimized. In Acute Leukemia VII - Experimental Approaches and Novel Therapies these topics are updated by leading scientists and clinicians around the world. The high quality of contributions makes this book a useful state-of-the-art report for both clinical oncologists and basic scientists and provides a comprehensive overview of the most recent achievements which translate into new treatment strategies and, hence, an improved outlook for patients suffering from acute leukemias | ||
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| id | DE-604.BV046147154 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T08:36:31Z |
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| isbn | 9783642719608 |
| language | English |
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| spelling | Acute Leukemias VII Experimental Approaches and Novel Therapies edited by W. Hiddemann, T. Büchner, B. Wörmann, J. Ritter, U. Creutzig, M. Keating, W. Plunkett With contributions by numerous experts Berlin, Heidelberg Springer Berlin Heidelberg 1998 1 Online-Ressource (XXXVIII, 1202 p. 205 illus) txt rdacontent c rdamedia cr rdacarrier Haematology and Blood Transfusion Hämatologie und Bluttransfusion 39 In the last few years there has been a dramatic increase in the knowledge about the biology of acute leukemias and, in particular, of the underlying genetic and molecular events. These processes lead to the deregulation of central transcription factors and genes regulating cell proliferation and differentiation and ultimately determine the response to chemotherapy and the long-term prognosis of patients suffering from these disorders. The increasing insights into the biology of acute leukemias also provide the basis for new pathogenetically oriented therapeutic strategies which aim at interfering with pathologically activated gene products or augmenting the antileukemic immune response. They give also new information about the mechanisms of action of conventional treatments and, in particular, cytostatic agents and thus allow drug regimens to be optimized. In Acute Leukemia VII - Experimental Approaches and Novel Therapies these topics are updated by leading scientists and clinicians around the world. The high quality of contributions makes this book a useful state-of-the-art report for both clinical oncologists and basic scientists and provides a comprehensive overview of the most recent achievements which translate into new treatment strategies and, hence, an improved outlook for patients suffering from acute leukemias Hematology Oncology Oncology Hiddemann, W. edt Büchner, T. edt Wörmann, B. edt Ritter, J. edt Erscheint auch als Druck-Ausgabe 9783642719622 Erscheint auch als Druck-Ausgabe 9783540635048 Erscheint auch als Druck-Ausgabe 9783642719615 https://doi.org/10.1007/978-3-642-71960-8 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Acute Leukemias VII Experimental Approaches and Novel Therapies Hematology Oncology Oncology |
| title | Acute Leukemias VII Experimental Approaches and Novel Therapies |
| title_alt | With contributions by numerous experts |
| title_auth | Acute Leukemias VII Experimental Approaches and Novel Therapies |
| title_exact_search | Acute Leukemias VII Experimental Approaches and Novel Therapies |
| title_full | Acute Leukemias VII Experimental Approaches and Novel Therapies edited by W. Hiddemann, T. Büchner, B. Wörmann, J. Ritter, U. Creutzig, M. Keating, W. Plunkett |
| title_fullStr | Acute Leukemias VII Experimental Approaches and Novel Therapies edited by W. Hiddemann, T. Büchner, B. Wörmann, J. Ritter, U. Creutzig, M. Keating, W. Plunkett |
| title_full_unstemmed | Acute Leukemias VII Experimental Approaches and Novel Therapies edited by W. Hiddemann, T. Büchner, B. Wörmann, J. Ritter, U. Creutzig, M. Keating, W. Plunkett |
| title_short | Acute Leukemias VII |
| title_sort | acute leukemias vii experimental approaches and novel therapies |
| title_sub | Experimental Approaches and Novel Therapies |
| topic | Hematology Oncology Oncology |
| topic_facet | Hematology Oncology Oncology |
| url | https://doi.org/10.1007/978-3-642-71960-8 |
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