Ökosystem Darm Special: Updates on Clostridium difficile
Jean-Claude Rambaud The place occupied today in basic and clinical research by intestinal disease related to Clostridium difficile is such that it is hard to remember that this range of disorders was completely identified only in 1977-1978, even though pieces of the puzzle had been identified much e...
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| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Paris
Springer Paris
1996
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| Online-Zugang: | UBR01 Volltext |
| Zusammenfassung: | Jean-Claude Rambaud The place occupied today in basic and clinical research by intestinal disease related to Clostridium difficile is such that it is hard to remember that this range of disorders was completely identified only in 1977-1978, even though pieces of the puzzle had been identified much earlier. A brief historical review of the discovery of the enteropathogenicity of C. difficile in man might thus be useful. The bacterium was described in 1935 in the stools of infants, using the name Bacillus difficilis [7]. Until 1977, the microorganism, renamed C. difficile, considered to be of endogenous origin, was isolated only in rare cases of abscess or infection, most often unrelated to the digestive tract. Its role in genito-urinary infections [6] was not confirmed. However, the frequency of infant healthy carriers was recognized from the outset [7, 13]. Pseudo-membranous colitis (PMC) was described in 1883 following a gastroenterostomy. Many cases of this condition were published subsequently before the antibiotic era, describing various risk factors [4]. However the disease began to flourish only with the increasingly wide use of antibiotics. Antibiotic associated PMC was first described as an enterocolitis, though with little pathological evidence. It was principally related to the use of chloramphenicol and tetracyclines and attributed to proliferation of Staphylococcus au reus [ 11], a concept strengthened by the spectacular therapeutic action of vancomycin |
| Beschreibung: | 1 Online-Ressource (X, 142 p. 56 illus., 8 illus. in color) |
| ISBN: | 9782817809243 |
| DOI: | 10.1007/978-2-8178-0924-3 |
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| 520 | |a Jean-Claude Rambaud The place occupied today in basic and clinical research by intestinal disease related to Clostridium difficile is such that it is hard to remember that this range of disorders was completely identified only in 1977-1978, even though pieces of the puzzle had been identified much earlier. A brief historical review of the discovery of the enteropathogenicity of C. difficile in man might thus be useful. The bacterium was described in 1935 in the stools of infants, using the name Bacillus difficilis [7]. Until 1977, the microorganism, renamed C. difficile, considered to be of endogenous origin, was isolated only in rare cases of abscess or infection, most often unrelated to the digestive tract. Its role in genito-urinary infections [6] was not confirmed. However, the frequency of infant healthy carriers was recognized from the outset [7, 13]. Pseudo-membranous colitis (PMC) was described in 1883 following a gastroenterostomy. Many cases of this condition were published subsequently before the antibiotic era, describing various risk factors [4]. However the disease began to flourish only with the increasingly wide use of antibiotics. Antibiotic associated PMC was first described as an enterocolitis, though with little pathological evidence. It was principally related to the use of chloramphenicol and tetracyclines and attributed to proliferation of Staphylococcus au reus [ 11], a concept strengthened by the spectacular therapeutic action of vancomycin | ||
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Datensatz im Suchindex
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| spelling | Ökosystem Darm Special Updates on Clostridium difficile edited by Jean-Claude Rambaud, J. Thomas LaMont With contributions by numerous experts Paris Springer Paris 1996 1 Online-Ressource (X, 142 p. 56 illus., 8 illus. in color) txt rdacontent c rdamedia cr rdacarrier Jean-Claude Rambaud The place occupied today in basic and clinical research by intestinal disease related to Clostridium difficile is such that it is hard to remember that this range of disorders was completely identified only in 1977-1978, even though pieces of the puzzle had been identified much earlier. A brief historical review of the discovery of the enteropathogenicity of C. difficile in man might thus be useful. The bacterium was described in 1935 in the stools of infants, using the name Bacillus difficilis [7]. Until 1977, the microorganism, renamed C. difficile, considered to be of endogenous origin, was isolated only in rare cases of abscess or infection, most often unrelated to the digestive tract. Its role in genito-urinary infections [6] was not confirmed. However, the frequency of infant healthy carriers was recognized from the outset [7, 13]. Pseudo-membranous colitis (PMC) was described in 1883 following a gastroenterostomy. Many cases of this condition were published subsequently before the antibiotic era, describing various risk factors [4]. However the disease began to flourish only with the increasingly wide use of antibiotics. Antibiotic associated PMC was first described as an enterocolitis, though with little pathological evidence. It was principally related to the use of chloramphenicol and tetracyclines and attributed to proliferation of Staphylococcus au reus [ 11], a concept strengthened by the spectacular therapeutic action of vancomycin Gastroenterology Virology Immunology Medical virology Clostridium-difficile-Infektion (DE-588)4253136-6 gnd rswk-swf Clostridium difficile (DE-588)4224047-5 gnd rswk-swf (DE-588)1071861417 Konferenzschrift 1995 Paris gnd-content Clostridium-difficile-Infektion (DE-588)4253136-6 s DE-604 Clostridium difficile (DE-588)4224047-5 s Rambaud, Jean-Claude edt LaMont, J. Thomas edt Erscheint auch als Druck-Ausgabe 9782287596391 Erscheint auch als Druck-Ausgabe 9782817809250 https://doi.org/10.1007/978-2-8178-0924-3 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Ökosystem Darm Special Updates on Clostridium difficile Gastroenterology Virology Immunology Medical virology Clostridium-difficile-Infektion (DE-588)4253136-6 gnd Clostridium difficile (DE-588)4224047-5 gnd |
| subject_GND | (DE-588)4253136-6 (DE-588)4224047-5 (DE-588)1071861417 |
| title | Ökosystem Darm Special Updates on Clostridium difficile |
| title_alt | With contributions by numerous experts |
| title_auth | Ökosystem Darm Special Updates on Clostridium difficile |
| title_exact_search | Ökosystem Darm Special Updates on Clostridium difficile |
| title_full | Ökosystem Darm Special Updates on Clostridium difficile edited by Jean-Claude Rambaud, J. Thomas LaMont |
| title_fullStr | Ökosystem Darm Special Updates on Clostridium difficile edited by Jean-Claude Rambaud, J. Thomas LaMont |
| title_full_unstemmed | Ökosystem Darm Special Updates on Clostridium difficile edited by Jean-Claude Rambaud, J. Thomas LaMont |
| title_short | Ökosystem Darm Special |
| title_sort | okosystem darm special updates on clostridium difficile |
| title_sub | Updates on Clostridium difficile |
| topic | Gastroenterology Virology Immunology Medical virology Clostridium-difficile-Infektion (DE-588)4253136-6 gnd Clostridium difficile (DE-588)4224047-5 gnd |
| topic_facet | Gastroenterology Virology Immunology Medical virology Clostridium-difficile-Infektion Clostridium difficile Konferenzschrift 1995 Paris |
| url | https://doi.org/10.1007/978-2-8178-0924-3 |
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