Advances in Nitrate Therapy:
Nitrates have been for many years the cornerstone of cardiovascular therapy for various indications. Not only have nitrates stood the test of time for treatment of chronic stable angina pectoris, but the indications for them have markedly ex panded. They now include all forms of angina pectoris and...
Gespeichert in:
| Hauptverfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Berlin, Heidelberg
Springer Berlin Heidelberg
1990
|
| Ausgabe: | Second, Revised and Enlarged Edition |
| Schlagworte: | |
| Online-Zugang: | UBR01 URL des Erstveröffentlichers |
| Zusammenfassung: | Nitrates have been for many years the cornerstone of cardiovascular therapy for various indications. Not only have nitrates stood the test of time for treatment of chronic stable angina pectoris, but the indications for them have markedly ex panded. They now include all forms of angina pectoris and myocardial ischemia, congestive heart failure and hypertensive emergencies. The beneficial effects of nitrates in all these conditions result from their vasodilatory properties, but it is still unclear whether the central or peripheral effects predominate in the thera peutic mechanism. Recently nitrates have been shown to fulfill the most important requirement for each and every drug - to reduce mortality. A large scale study revealed that isosorbide dinitrate, combined with hydralazine, reduced long-term mortality by 28% in patients with congestive heart failure. This finding will certainly stimulate research on nitrates, and it might be expected that interest in these drugs will markedly increase. The primarily used nitrates in clinical practice are nitroglycerin and the com plex organic nitrates, mainly isosorbide dinitrate. The organic mononitrates are now under clinical investigation, and isosorbide-5-mononitrate (IS-5-MN) appears to be especially promising |
| Beschreibung: | 1 Online-Ressource (IV, 206 p) |
| ISBN: | 9783642758348 |
| DOI: | 10.1007/978-3-642-75834-8 |
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| 520 | |a Nitrates have been for many years the cornerstone of cardiovascular therapy for various indications. Not only have nitrates stood the test of time for treatment of chronic stable angina pectoris, but the indications for them have markedly ex panded. They now include all forms of angina pectoris and myocardial ischemia, congestive heart failure and hypertensive emergencies. The beneficial effects of nitrates in all these conditions result from their vasodilatory properties, but it is still unclear whether the central or peripheral effects predominate in the thera peutic mechanism. Recently nitrates have been shown to fulfill the most important requirement for each and every drug - to reduce mortality. A large scale study revealed that isosorbide dinitrate, combined with hydralazine, reduced long-term mortality by 28% in patients with congestive heart failure. This finding will certainly stimulate research on nitrates, and it might be expected that interest in these drugs will markedly increase. The primarily used nitrates in clinical practice are nitroglycerin and the com plex organic nitrates, mainly isosorbide dinitrate. The organic mononitrates are now under clinical investigation, and isosorbide-5-mononitrate (IS-5-MN) appears to be especially promising | ||
| 650 | 4 | |a Cardiology | |
| 650 | 4 | |a Pharmacology/Toxicology | |
| 650 | 4 | |a Nephrology | |
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Datensatz im Suchindex
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| author | Schneeweiss, Adam Weiss, Marija |
| author_facet | Schneeweiss, Adam Weiss, Marija |
| author_role | aut aut |
| author_sort | Schneeweiss, Adam |
| author_variant | a s as m w mw |
| building | Verbundindex |
| bvnumber | BV046147056 |
| collection | ZDB-2-SME |
| ctrlnum | (ZDB-2-SME)978-3-642-75834-8 (OCoLC)1119032366 (DE-599)BVBBV046147056 |
| dewey-full | 616.12 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 616 - Diseases |
| dewey-raw | 616.12 |
| dewey-search | 616.12 |
| dewey-sort | 3616.12 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| doi_str_mv | 10.1007/978-3-642-75834-8 |
| edition | Second, Revised and Enlarged Edition |
| format | Electronic eBook |
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| id | DE-604.BV046147056 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T08:36:31Z |
| institution | BVB |
| isbn | 9783642758348 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-031527241 |
| oclc_num | 1119032366 |
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| owner_facet | DE-355 DE-BY-UBR |
| physical | 1 Online-Ressource (IV, 206 p) |
| psigel | ZDB-2-SME ZDB-2-SME_1990/2004 ZDB-2-SME ZDB-2-SME_1990/2004 |
| publishDate | 1990 |
| publishDateSearch | 1990 |
| publishDateSort | 1990 |
| publisher | Springer Berlin Heidelberg |
| record_format | marc |
| spelling | Schneeweiss, Adam Verfasser aut Advances in Nitrate Therapy by Adam Schneeweiss, Marija Weiss Second, Revised and Enlarged Edition Berlin, Heidelberg Springer Berlin Heidelberg 1990 1 Online-Ressource (IV, 206 p) txt rdacontent c rdamedia cr rdacarrier Nitrates have been for many years the cornerstone of cardiovascular therapy for various indications. Not only have nitrates stood the test of time for treatment of chronic stable angina pectoris, but the indications for them have markedly ex panded. They now include all forms of angina pectoris and myocardial ischemia, congestive heart failure and hypertensive emergencies. The beneficial effects of nitrates in all these conditions result from their vasodilatory properties, but it is still unclear whether the central or peripheral effects predominate in the thera peutic mechanism. Recently nitrates have been shown to fulfill the most important requirement for each and every drug - to reduce mortality. A large scale study revealed that isosorbide dinitrate, combined with hydralazine, reduced long-term mortality by 28% in patients with congestive heart failure. This finding will certainly stimulate research on nitrates, and it might be expected that interest in these drugs will markedly increase. The primarily used nitrates in clinical practice are nitroglycerin and the com plex organic nitrates, mainly isosorbide dinitrate. The organic mononitrates are now under clinical investigation, and isosorbide-5-mononitrate (IS-5-MN) appears to be especially promising Cardiology Pharmacology/Toxicology Nephrology Toxicology Nitrattherapie (DE-588)4137903-2 gnd rswk-swf Nitrattherapie (DE-588)4137903-2 s DE-604 Weiss, Marija aut Erscheint auch als Druck-Ausgabe 9783642758362 Erscheint auch als Druck-Ausgabe 9783540527985 Erscheint auch als Druck-Ausgabe 9783642758355 https://doi.org/10.1007/978-3-642-75834-8 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Schneeweiss, Adam Weiss, Marija Advances in Nitrate Therapy Cardiology Pharmacology/Toxicology Nephrology Toxicology Nitrattherapie (DE-588)4137903-2 gnd |
| subject_GND | (DE-588)4137903-2 |
| title | Advances in Nitrate Therapy |
| title_auth | Advances in Nitrate Therapy |
| title_exact_search | Advances in Nitrate Therapy |
| title_full | Advances in Nitrate Therapy by Adam Schneeweiss, Marija Weiss |
| title_fullStr | Advances in Nitrate Therapy by Adam Schneeweiss, Marija Weiss |
| title_full_unstemmed | Advances in Nitrate Therapy by Adam Schneeweiss, Marija Weiss |
| title_short | Advances in Nitrate Therapy |
| title_sort | advances in nitrate therapy |
| topic | Cardiology Pharmacology/Toxicology Nephrology Toxicology Nitrattherapie (DE-588)4137903-2 gnd |
| topic_facet | Cardiology Pharmacology/Toxicology Nephrology Toxicology Nitrattherapie |
| url | https://doi.org/10.1007/978-3-642-75834-8 |
| work_keys_str_mv | AT schneeweissadam advancesinnitratetherapy AT weissmarija advancesinnitratetherapy |