Cancer Neutron Capture Therapy:
There are many human cancers which actively synthesize specific characteristic proteins such as melanomas, thyroid cancer and squamous cell carcinoma. Many cancer researchers have of course tried to utilize this specific activity as a key for the selective treatment of cancers. In the past for examp...
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| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Boston, MA
Springer US
1996
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| Schlagworte: | |
| Online-Zugang: | UBR01 Volltext |
| Zusammenfassung: | There are many human cancers which actively synthesize specific characteristic proteins such as melanomas, thyroid cancer and squamous cell carcinoma. Many cancer researchers have of course tried to utilize this specific activity as a key for the selective treatment of cancers. In the past for example, the molecular hybrid compound of DOPA, a substrate of melanin, and nitrogen mustard N-oxide hydrochloride, a ctyotoxic anti-tumor drug, was synthesized as Melphalan and used to treat malignant melanoma. A major problem arose though in that it was soon found to be highly suppressive toward bone marrow and quite toxic while not being remarkably effective. Thus, malignant melanoma could not be cured by it. Such failure led us to develop a novel bimodal therapeutic system which includes the use of non-toxic potentially cytocidal chemicals which selectively accumulate within the cancer cells and which are converted by a controllable modality into an actively cytocidal element in situ. We can now non-surgically cure malignant melanoma and glioblastoma with our selective cancer treatment, neutron capture therapy (NCT); as can be found in this volume. Included are 124 papers on the latest breaking developments discussed at the Sixth International Symposium on NCT for Cancer held in Kobe during the late autumn of 1994 |
| Beschreibung: | 1 Online-Ressource (XXVII, 920 p) |
| ISBN: | 9781475795677 |
| DOI: | 10.1007/978-1-4757-9567-7 |
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| 520 | |a There are many human cancers which actively synthesize specific characteristic proteins such as melanomas, thyroid cancer and squamous cell carcinoma. Many cancer researchers have of course tried to utilize this specific activity as a key for the selective treatment of cancers. In the past for example, the molecular hybrid compound of DOPA, a substrate of melanin, and nitrogen mustard N-oxide hydrochloride, a ctyotoxic anti-tumor drug, was synthesized as Melphalan and used to treat malignant melanoma. A major problem arose though in that it was soon found to be highly suppressive toward bone marrow and quite toxic while not being remarkably effective. Thus, malignant melanoma could not be cured by it. Such failure led us to develop a novel bimodal therapeutic system which includes the use of non-toxic potentially cytocidal chemicals which selectively accumulate within the cancer cells and which are converted by a controllable modality into an actively cytocidal element in situ. We can now non-surgically cure malignant melanoma and glioblastoma with our selective cancer treatment, neutron capture therapy (NCT); as can be found in this volume. Included are 124 papers on the latest breaking developments discussed at the Sixth International Symposium on NCT for Cancer held in Kobe during the late autumn of 1994 | ||
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| isbn | 9781475795677 |
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| spelling | Cancer Neutron Capture Therapy edited by Yutaka Mishima Boston, MA Springer US 1996 1 Online-Ressource (XXVII, 920 p) txt rdacontent c rdamedia cr rdacarrier There are many human cancers which actively synthesize specific characteristic proteins such as melanomas, thyroid cancer and squamous cell carcinoma. Many cancer researchers have of course tried to utilize this specific activity as a key for the selective treatment of cancers. In the past for example, the molecular hybrid compound of DOPA, a substrate of melanin, and nitrogen mustard N-oxide hydrochloride, a ctyotoxic anti-tumor drug, was synthesized as Melphalan and used to treat malignant melanoma. A major problem arose though in that it was soon found to be highly suppressive toward bone marrow and quite toxic while not being remarkably effective. Thus, malignant melanoma could not be cured by it. Such failure led us to develop a novel bimodal therapeutic system which includes the use of non-toxic potentially cytocidal chemicals which selectively accumulate within the cancer cells and which are converted by a controllable modality into an actively cytocidal element in situ. We can now non-surgically cure malignant melanoma and glioblastoma with our selective cancer treatment, neutron capture therapy (NCT); as can be found in this volume. Included are 124 papers on the latest breaking developments discussed at the Sixth International Symposium on NCT for Cancer held in Kobe during the late autumn of 1994 Oncology Dermatology Nuclear Medicine Ultrasound Biological and Medical Physics, Biophysics Nuclear Physics, Heavy Ions, Hadrons Oncology Nuclear medicine Diagnosis, Ultrasonic Nuclear physics Neutroneneinfangtherapie (DE-588)4596398-8 gnd rswk-swf 1\p (DE-588)1071861417 Konferenzschrift 1994 Kobe gnd-content Neutroneneinfangtherapie (DE-588)4596398-8 s 2\p DE-604 Mishima, Yutaka edt Erscheint auch als Druck-Ausgabe 9781475795691 Erscheint auch als Druck-Ausgabe 9781475795684 Erscheint auch als Druck-Ausgabe 9780306453076 https://doi.org/10.1007/978-1-4757-9567-7 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 2\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Cancer Neutron Capture Therapy Oncology Dermatology Nuclear Medicine Ultrasound Biological and Medical Physics, Biophysics Nuclear Physics, Heavy Ions, Hadrons Oncology Nuclear medicine Diagnosis, Ultrasonic Nuclear physics Neutroneneinfangtherapie (DE-588)4596398-8 gnd |
| subject_GND | (DE-588)4596398-8 (DE-588)1071861417 |
| title | Cancer Neutron Capture Therapy |
| title_auth | Cancer Neutron Capture Therapy |
| title_exact_search | Cancer Neutron Capture Therapy |
| title_full | Cancer Neutron Capture Therapy edited by Yutaka Mishima |
| title_fullStr | Cancer Neutron Capture Therapy edited by Yutaka Mishima |
| title_full_unstemmed | Cancer Neutron Capture Therapy edited by Yutaka Mishima |
| title_short | Cancer Neutron Capture Therapy |
| title_sort | cancer neutron capture therapy |
| topic | Oncology Dermatology Nuclear Medicine Ultrasound Biological and Medical Physics, Biophysics Nuclear Physics, Heavy Ions, Hadrons Oncology Nuclear medicine Diagnosis, Ultrasonic Nuclear physics Neutroneneinfangtherapie (DE-588)4596398-8 gnd |
| topic_facet | Oncology Dermatology Nuclear Medicine Ultrasound Biological and Medical Physics, Biophysics Nuclear Physics, Heavy Ions, Hadrons Oncology Nuclear medicine Diagnosis, Ultrasonic Nuclear physics Neutroneneinfangtherapie Konferenzschrift 1994 Kobe |
| url | https://doi.org/10.1007/978-1-4757-9567-7 |
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