Clinical and Diagnostic Pathology of Graft-versus-Host Disease:
Graft-versus-host Disease (GvHD) occurs primarily but not exclusively as a complication in the context of allogeneic bone marrow or peripheral blood stem cell transplantation (BMT or PBSCT), the treatment of choice for various life-threatening diseases. GvHD may affect skin, liver, gut, and other or...
Gespeichert in:
| 1. Verfasser: | |
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| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Berlin, Heidelberg
Springer Berlin Heidelberg
2002
|
| Schlagworte: | |
| Online-Zugang: | UBR01 Volltext |
| Zusammenfassung: | Graft-versus-host Disease (GvHD) occurs primarily but not exclusively as a complication in the context of allogeneic bone marrow or peripheral blood stem cell transplantation (BMT or PBSCT), the treatment of choice for various life-threatening diseases. GvHD may affect skin, liver, gut, and other organs and sometimes runs a devastating or even lethal course. The diagnosis of GvHD is based on both clinical and histomorphological parameters. However, due to the widespread use of GvHD prophylaxis in patients undergoing allogeneic BMT or PBSCT, the number of histologically typical lesions has decreased, while the number of atypical, low-grade or masked lesions has increased. Therefore, an update of the clinical and diagnostic pathology of GvHD of skin, liver, gastrointestinal tract and other organs is required. In the present volume the histological features of GvHD lesions under today's conditions are described and illustrated in detail. Particular emphasis is placed on differential diagnostic problems and histodiagnostic pitfalls. Finally, the applicability and limits of immunohistological methods for the diagnosis of GvHD are shown |
| Beschreibung: | 1 Online-Ressource (XVI, 156 p. 79 illus., 78 illus. in color) |
| ISBN: | 9783662047156 |
| DOI: | 10.1007/978-3-662-04715-6 |
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| 520 | |a Graft-versus-host Disease (GvHD) occurs primarily but not exclusively as a complication in the context of allogeneic bone marrow or peripheral blood stem cell transplantation (BMT or PBSCT), the treatment of choice for various life-threatening diseases. GvHD may affect skin, liver, gut, and other organs and sometimes runs a devastating or even lethal course. The diagnosis of GvHD is based on both clinical and histomorphological parameters. However, due to the widespread use of GvHD prophylaxis in patients undergoing allogeneic BMT or PBSCT, the number of histologically typical lesions has decreased, while the number of atypical, low-grade or masked lesions has increased. Therefore, an update of the clinical and diagnostic pathology of GvHD of skin, liver, gastrointestinal tract and other organs is required. In the present volume the histological features of GvHD lesions under today's conditions are described and illustrated in detail. Particular emphasis is placed on differential diagnostic problems and histodiagnostic pitfalls. Finally, the applicability and limits of immunohistological methods for the diagnosis of GvHD are shown | ||
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| spelling | Heymer, Berno Verfasser aut Clinical and Diagnostic Pathology of Graft-versus-Host Disease by Berno Heymer Berlin, Heidelberg Springer Berlin Heidelberg 2002 1 Online-Ressource (XVI, 156 p. 79 illus., 78 illus. in color) txt rdacontent c rdamedia cr rdacarrier Graft-versus-host Disease (GvHD) occurs primarily but not exclusively as a complication in the context of allogeneic bone marrow or peripheral blood stem cell transplantation (BMT or PBSCT), the treatment of choice for various life-threatening diseases. GvHD may affect skin, liver, gut, and other organs and sometimes runs a devastating or even lethal course. The diagnosis of GvHD is based on both clinical and histomorphological parameters. However, due to the widespread use of GvHD prophylaxis in patients undergoing allogeneic BMT or PBSCT, the number of histologically typical lesions has decreased, while the number of atypical, low-grade or masked lesions has increased. Therefore, an update of the clinical and diagnostic pathology of GvHD of skin, liver, gastrointestinal tract and other organs is required. In the present volume the histological features of GvHD lesions under today's conditions are described and illustrated in detail. Particular emphasis is placed on differential diagnostic problems and histodiagnostic pitfalls. Finally, the applicability and limits of immunohistological methods for the diagnosis of GvHD are shown Pathology Oncology Hematology Transplant Surgery Pediatrics Oncology Transplantation of organs, tissu Transplantat-Wirt-Reaktion (DE-588)4158009-6 gnd rswk-swf Pathologie (DE-588)4044893-9 gnd rswk-swf Transplantat-Wirt-Reaktion (DE-588)4158009-6 s Pathologie (DE-588)4044893-9 s DE-604 Erscheint auch als Druck-Ausgabe 9783642087219 Erscheint auch als Druck-Ausgabe 9783662047163 Erscheint auch als Druck-Ausgabe 9783540677192 https://doi.org/10.1007/978-3-662-04715-6 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Heymer, Berno Clinical and Diagnostic Pathology of Graft-versus-Host Disease Pathology Oncology Hematology Transplant Surgery Pediatrics Oncology Transplantation of organs, tissu Transplantat-Wirt-Reaktion (DE-588)4158009-6 gnd Pathologie (DE-588)4044893-9 gnd |
| subject_GND | (DE-588)4158009-6 (DE-588)4044893-9 |
| title | Clinical and Diagnostic Pathology of Graft-versus-Host Disease |
| title_auth | Clinical and Diagnostic Pathology of Graft-versus-Host Disease |
| title_exact_search | Clinical and Diagnostic Pathology of Graft-versus-Host Disease |
| title_full | Clinical and Diagnostic Pathology of Graft-versus-Host Disease by Berno Heymer |
| title_fullStr | Clinical and Diagnostic Pathology of Graft-versus-Host Disease by Berno Heymer |
| title_full_unstemmed | Clinical and Diagnostic Pathology of Graft-versus-Host Disease by Berno Heymer |
| title_short | Clinical and Diagnostic Pathology of Graft-versus-Host Disease |
| title_sort | clinical and diagnostic pathology of graft versus host disease |
| topic | Pathology Oncology Hematology Transplant Surgery Pediatrics Oncology Transplantation of organs, tissu Transplantat-Wirt-Reaktion (DE-588)4158009-6 gnd Pathologie (DE-588)4044893-9 gnd |
| topic_facet | Pathology Oncology Hematology Transplant Surgery Pediatrics Oncology Transplantation of organs, tissu Transplantat-Wirt-Reaktion Pathologie |
| url | https://doi.org/10.1007/978-3-662-04715-6 |
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