Autoimmunity and the Pathogenesis of Diabetes:
It has been a challenge for us to edit this volume of Endocrinology and Metabo lism: Progress in Research and Clinical Practice. The topic of the pathogenesis of insulin-dependent, type I diabetes mellitus is particularly appropriate for this series, since advances in this area have been made, to a...
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
New York, NY
Springer New York
1990
|
| Schriftenreihe: | Endocrinology and Metabolism, Progress in Research and Clinical Practice
4 |
| Schlagworte: | |
| Online-Zugang: | UBR01 Volltext |
| Zusammenfassung: | It has been a challenge for us to edit this volume of Endocrinology and Metabo lism: Progress in Research and Clinical Practice. The topic of the pathogenesis of insulin-dependent, type I diabetes mellitus is particularly appropriate for this series, since advances in this area have been made, to a large extent, by applying state-of-the-art laboratory techniques to clinical samples. Over the last several years, a number of lines of evidence have been gathered, suggesting that classic type I diabetes mellitus results from the autoimmune des truction of pancreatic beta-cells in genetically susceptible individuals. This hypothesis is particularly appealing because it offers a rational approach to the prevention of diabetes by immunosuppression. We have tried to present a balanced, authoritative summary of the information currently available to support the autoimmune hypothesis for the pathogenesis of human type I diabetes, to place this information in historical perspective, to include relevant information from animal models of type I diabetes in which more invasive experimentation is ethical, and, finally, to update the reader on the current status of attempts to intervene in the progression of diabetes with immunosuppressive drugs. New York, New York Fredda Ginsberg-Fellner Robert C. McEvoy Contents Preface.. . . .. .. .. . . . . . . . . . . . . ... . . . . . . . . . . . .. . . . . . . .. . . . . v Contributors. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Xl . . . . . . . . . . . . . 1. The Autoimmune Hypothesis of Insulin-Dependent Diabetes: 1965 to the Present . . . . . . . . . . . . ..................... . . . . . |
| Beschreibung: | 1 Online-Ressource (XII, 296 p) |
| ISBN: | 9781461232186 |
| DOI: | 10.1007/978-1-4612-3218-6 |
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| 520 | |a It has been a challenge for us to edit this volume of Endocrinology and Metabo lism: Progress in Research and Clinical Practice. The topic of the pathogenesis of insulin-dependent, type I diabetes mellitus is particularly appropriate for this series, since advances in this area have been made, to a large extent, by applying state-of-the-art laboratory techniques to clinical samples. Over the last several years, a number of lines of evidence have been gathered, suggesting that classic type I diabetes mellitus results from the autoimmune des truction of pancreatic beta-cells in genetically susceptible individuals. This hypothesis is particularly appealing because it offers a rational approach to the prevention of diabetes by immunosuppression. We have tried to present a balanced, authoritative summary of the information currently available to support the autoimmune hypothesis for the pathogenesis of human type I diabetes, to place this information in historical perspective, to include relevant information from animal models of type I diabetes in which more invasive experimentation is ethical, and, finally, to update the reader on the current status of attempts to intervene in the progression of diabetes with immunosuppressive drugs. New York, New York Fredda Ginsberg-Fellner Robert C. McEvoy Contents Preface.. . . .. .. .. . . . . . . . . . . . . ... . . . . . . . . . . . .. . . . . . . .. . . . . v Contributors. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Xl . . . . . . . . . . . . . 1. The Autoimmune Hypothesis of Insulin-Dependent Diabetes: 1965 to the Present . . . . . . . . . . . . ..................... . . . . . | ||
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| discipline | Medizin |
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| indexdate | 2024-07-10T08:36:30Z |
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| isbn | 9781461232186 |
| language | English |
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| spelling | Autoimmunity and the Pathogenesis of Diabetes edited by Fredda Ginsberg-Fellner, Robert C. McEvoy New York, NY Springer New York 1990 1 Online-Ressource (XII, 296 p) txt rdacontent c rdamedia cr rdacarrier Endocrinology and Metabolism, Progress in Research and Clinical Practice 4 It has been a challenge for us to edit this volume of Endocrinology and Metabo lism: Progress in Research and Clinical Practice. The topic of the pathogenesis of insulin-dependent, type I diabetes mellitus is particularly appropriate for this series, since advances in this area have been made, to a large extent, by applying state-of-the-art laboratory techniques to clinical samples. Over the last several years, a number of lines of evidence have been gathered, suggesting that classic type I diabetes mellitus results from the autoimmune des truction of pancreatic beta-cells in genetically susceptible individuals. This hypothesis is particularly appealing because it offers a rational approach to the prevention of diabetes by immunosuppression. We have tried to present a balanced, authoritative summary of the information currently available to support the autoimmune hypothesis for the pathogenesis of human type I diabetes, to place this information in historical perspective, to include relevant information from animal models of type I diabetes in which more invasive experimentation is ethical, and, finally, to update the reader on the current status of attempts to intervene in the progression of diabetes with immunosuppressive drugs. New York, New York Fredda Ginsberg-Fellner Robert C. McEvoy Contents Preface.. . . .. .. .. . . . . . . . . . . . . ... . . . . . . . . . . . .. . . . . . . .. . . . . v Contributors. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Xl . . . . . . . . . . . . . 1. The Autoimmune Hypothesis of Insulin-Dependent Diabetes: 1965 to the Present . . . . . . . . . . . . ..................... . . . . . Endocrinology Allergology Immunology Metabolic Diseases Virology Human Genetics Allergy Metabolic diseases Medical virology Human genetics Typ 1 (DE-588)4326602-2 gnd rswk-swf Autoaggressionskrankheit (DE-588)4003935-3 gnd rswk-swf Diabetes mellitus (DE-588)4070446-4 gnd rswk-swf Diabetes mellitus Typ 1 (DE-588)1194595685 gnd rswk-swf Pathogenese (DE-588)4115512-9 gnd rswk-swf Autoimmunität (DE-588)4319435-7 gnd rswk-swf Diabetes mellitus Typ 1 (DE-588)1194595685 s Typ 1 (DE-588)4326602-2 s Autoaggressionskrankheit (DE-588)4003935-3 s Pathogenese (DE-588)4115512-9 s DE-604 Diabetes mellitus (DE-588)4070446-4 s Autoimmunität (DE-588)4319435-7 s Ginsberg-Fellner, Fredda edt McEvoy, Robert C. edt Erscheint auch als Druck-Ausgabe 9781461279204 Erscheint auch als Druck-Ausgabe 9780387966458 Erscheint auch als Druck-Ausgabe 9781461232193 https://doi.org/10.1007/978-1-4612-3218-6 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Autoimmunity and the Pathogenesis of Diabetes Endocrinology Allergology Immunology Metabolic Diseases Virology Human Genetics Allergy Metabolic diseases Medical virology Human genetics Typ 1 (DE-588)4326602-2 gnd Autoaggressionskrankheit (DE-588)4003935-3 gnd Diabetes mellitus (DE-588)4070446-4 gnd Diabetes mellitus Typ 1 (DE-588)1194595685 gnd Pathogenese (DE-588)4115512-9 gnd Autoimmunität (DE-588)4319435-7 gnd |
| subject_GND | (DE-588)4326602-2 (DE-588)4003935-3 (DE-588)4070446-4 (DE-588)1194595685 (DE-588)4115512-9 (DE-588)4319435-7 |
| title | Autoimmunity and the Pathogenesis of Diabetes |
| title_auth | Autoimmunity and the Pathogenesis of Diabetes |
| title_exact_search | Autoimmunity and the Pathogenesis of Diabetes |
| title_full | Autoimmunity and the Pathogenesis of Diabetes edited by Fredda Ginsberg-Fellner, Robert C. McEvoy |
| title_fullStr | Autoimmunity and the Pathogenesis of Diabetes edited by Fredda Ginsberg-Fellner, Robert C. McEvoy |
| title_full_unstemmed | Autoimmunity and the Pathogenesis of Diabetes edited by Fredda Ginsberg-Fellner, Robert C. McEvoy |
| title_short | Autoimmunity and the Pathogenesis of Diabetes |
| title_sort | autoimmunity and the pathogenesis of diabetes |
| topic | Endocrinology Allergology Immunology Metabolic Diseases Virology Human Genetics Allergy Metabolic diseases Medical virology Human genetics Typ 1 (DE-588)4326602-2 gnd Autoaggressionskrankheit (DE-588)4003935-3 gnd Diabetes mellitus (DE-588)4070446-4 gnd Diabetes mellitus Typ 1 (DE-588)1194595685 gnd Pathogenese (DE-588)4115512-9 gnd Autoimmunität (DE-588)4319435-7 gnd |
| topic_facet | Endocrinology Allergology Immunology Metabolic Diseases Virology Human Genetics Allergy Metabolic diseases Medical virology Human genetics Typ 1 Autoaggressionskrankheit Diabetes mellitus Diabetes mellitus Typ 1 Pathogenese Autoimmunität |
| url | https://doi.org/10.1007/978-1-4612-3218-6 |
| work_keys_str_mv | AT ginsbergfellnerfredda autoimmunityandthepathogenesisofdiabetes AT mcevoyrobertc autoimmunityandthepathogenesisofdiabetes |