Applications of Pharmacokinetic Principles in Drug Development:
This volume is an important advancement in the application ofpharmacokinetic (PK) and pharmacodynamic (PO) principles to . drug development. The series of topics presented deal with the application of these tools to everyday decisions that a pharmaceutical scientist encounters. The ability to integr...
Gespeichert in:
| Weitere Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Boston, MA
Springer US
2004
|
| Schlagworte: | |
| Online-Zugang: | UBR01 URL des Erstveröffentlichers |
| Zusammenfassung: | This volume is an important advancement in the application ofpharmacokinetic (PK) and pharmacodynamic (PO) principles to . drug development. The series of topics presented deal with the application of these tools to everyday decisions that a pharmaceutical scientist encounters. The ability to integrate these topics using PK and PO methods has optimized drug development pathways in the clinic. New technologies in the areas of in vitro assays that are more predictive of human absorption and metabolism and advancement in bioanalytical assays are leading the way to minimize drug failures in later, more expensive clinical development programs. of Pharmacokinetics and pharmacodynamics have become an important component understanding the drug action on the body and is becoming increasingly important in drug labeling due to it's potential for predicting drug behavior in populations that may be difficult to study in adequate numbers during drug development. The ability to correlate drug exposure to effect and model it during the drug development value chain provides valuable insight into optimizing the next steps to derive maximum information from each study. These principles and modeling techniques have resulted in an expanded and integrated view of PK and PO and have led to the expectations that we may be able to optimally design clinical trials and eventually lead us to identifying the optimal therapy for the patient, while minimizing cost and speeding up drug development. There is wide utility for the book both as a text and as a reference |
| Beschreibung: | 1 Online-Ressource (XVI, 550 p) |
| ISBN: | 9781441992161 |
| DOI: | 10.1007/978-1-4419-9216-1 |
Internformat
MARC
| LEADER | 00000nmm a2200000zc 4500 | ||
|---|---|---|---|
| 001 | BV046146449 | ||
| 003 | DE-604 | ||
| 005 | 00000000000000.0 | ||
| 007 | cr|uuu---uuuuu | ||
| 008 | 190905s2004 |||| o||u| ||||||eng d | ||
| 020 | |a 9781441992161 |9 978-1-4419-9216-1 | ||
| 024 | 7 | |a 10.1007/978-1-4419-9216-1 |2 doi | |
| 035 | |a (ZDB-2-SME)978-1-4419-9216-1 | ||
| 035 | |a (OCoLC)1119113454 | ||
| 035 | |a (DE-599)BVBBV046146449 | ||
| 040 | |a DE-604 |b ger |e aacr | ||
| 041 | 0 | |a eng | |
| 049 | |a DE-355 | ||
| 082 | 0 | |a 636.089 |2 23 | |
| 245 | 1 | 0 | |a Applications of Pharmacokinetic Principles in Drug Development |c edited by Rajesh Krishna |
| 264 | 1 | |a Boston, MA |b Springer US |c 2004 | |
| 300 | |a 1 Online-Ressource (XVI, 550 p) | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b c |2 rdamedia | ||
| 338 | |b cr |2 rdacarrier | ||
| 520 | |a This volume is an important advancement in the application ofpharmacokinetic (PK) and pharmacodynamic (PO) principles to . drug development. The series of topics presented deal with the application of these tools to everyday decisions that a pharmaceutical scientist encounters. The ability to integrate these topics using PK and PO methods has optimized drug development pathways in the clinic. New technologies in the areas of in vitro assays that are more predictive of human absorption and metabolism and advancement in bioanalytical assays are leading the way to minimize drug failures in later, more expensive clinical development programs. of Pharmacokinetics and pharmacodynamics have become an important component understanding the drug action on the body and is becoming increasingly important in drug labeling due to it's potential for predicting drug behavior in populations that may be difficult to study in adequate numbers during drug development. The ability to correlate drug exposure to effect and model it during the drug development value chain provides valuable insight into optimizing the next steps to derive maximum information from each study. These principles and modeling techniques have resulted in an expanded and integrated view of PK and PO and have led to the expectations that we may be able to optimally design clinical trials and eventually lead us to identifying the optimal therapy for the patient, while minimizing cost and speeding up drug development. There is wide utility for the book both as a text and as a reference | ||
| 650 | 4 | |a Veterinary Medicine/Veterinary Science | |
| 650 | 4 | |a Biochemistry, general | |
| 650 | 4 | |a Pharmacy | |
| 650 | 4 | |a Evolutionary Biology | |
| 650 | 4 | |a Veterinary medicine | |
| 650 | 4 | |a Biochemistry | |
| 650 | 4 | |a Pharmacy | |
| 650 | 4 | |a Evolution (Biology) | |
| 700 | 1 | |a Krishna, Rajesh |4 edt | |
| 776 | 0 | 8 | |i Erscheint auch als |n Druck-Ausgabe |z 9781461348429 |
| 776 | 0 | 8 | |i Erscheint auch als |n Druck-Ausgabe |z 9780306477669 |
| 776 | 0 | 8 | |i Erscheint auch als |n Druck-Ausgabe |z 9781441992178 |
| 856 | 4 | 0 | |u https://doi.org/10.1007/978-1-4419-9216-1 |x Verlag |z URL des Erstveröffentlichers |3 Volltext |
| 912 | |a ZDB-2-SME | ||
| 940 | 1 | |q ZDB-2-SME_1990/2004 | |
| 999 | |a oai:aleph.bib-bvb.de:BVB01-031526634 | ||
| 966 | e | |u https://doi.org/10.1007/978-1-4419-9216-1 |l UBR01 |p ZDB-2-SME |q ZDB-2-SME_1990/2004 |x Verlag |3 Volltext | |
Datensatz im Suchindex
| _version_ | 1804180484458020864 |
|---|---|
| any_adam_object | |
| author2 | Krishna, Rajesh |
| author2_role | edt |
| author2_variant | r k rk |
| author_facet | Krishna, Rajesh |
| building | Verbundindex |
| bvnumber | BV046146449 |
| collection | ZDB-2-SME |
| ctrlnum | (ZDB-2-SME)978-1-4419-9216-1 (OCoLC)1119113454 (DE-599)BVBBV046146449 |
| dewey-full | 636.089 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 636 - Animal husbandry |
| dewey-raw | 636.089 |
| dewey-search | 636.089 |
| dewey-sort | 3636.089 |
| dewey-tens | 630 - Agriculture and related technologies |
| discipline | Agrar-/Forst-/Ernährungs-/Haushaltswissenschaft / Gartenbau Medizin |
| doi_str_mv | 10.1007/978-1-4419-9216-1 |
| format | Electronic eBook |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>03214nmm a2200481zc 4500</leader><controlfield tag="001">BV046146449</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">00000000000000.0</controlfield><controlfield tag="007">cr|uuu---uuuuu</controlfield><controlfield tag="008">190905s2004 |||| o||u| ||||||eng d</controlfield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9781441992161</subfield><subfield code="9">978-1-4419-9216-1</subfield></datafield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1007/978-1-4419-9216-1</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ZDB-2-SME)978-1-4419-9216-1</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)1119113454</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV046146449</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">aacr</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-355</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">636.089</subfield><subfield code="2">23</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Applications of Pharmacokinetic Principles in Drug Development</subfield><subfield code="c">edited by Rajesh Krishna</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Boston, MA</subfield><subfield code="b">Springer US</subfield><subfield code="c">2004</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 Online-Ressource (XVI, 550 p)</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">This volume is an important advancement in the application ofpharmacokinetic (PK) and pharmacodynamic (PO) principles to . drug development. The series of topics presented deal with the application of these tools to everyday decisions that a pharmaceutical scientist encounters. The ability to integrate these topics using PK and PO methods has optimized drug development pathways in the clinic. New technologies in the areas of in vitro assays that are more predictive of human absorption and metabolism and advancement in bioanalytical assays are leading the way to minimize drug failures in later, more expensive clinical development programs. of Pharmacokinetics and pharmacodynamics have become an important component understanding the drug action on the body and is becoming increasingly important in drug labeling due to it's potential for predicting drug behavior in populations that may be difficult to study in adequate numbers during drug development. The ability to correlate drug exposure to effect and model it during the drug development value chain provides valuable insight into optimizing the next steps to derive maximum information from each study. These principles and modeling techniques have resulted in an expanded and integrated view of PK and PO and have led to the expectations that we may be able to optimally design clinical trials and eventually lead us to identifying the optimal therapy for the patient, while minimizing cost and speeding up drug development. There is wide utility for the book both as a text and as a reference</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Veterinary Medicine/Veterinary Science</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Biochemistry, general</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Pharmacy</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Evolutionary Biology</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Veterinary medicine</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Biochemistry</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Pharmacy</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Evolution (Biology)</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Krishna, Rajesh</subfield><subfield code="4">edt</subfield></datafield><datafield tag="776" ind1="0" ind2="8"><subfield code="i">Erscheint auch als</subfield><subfield code="n">Druck-Ausgabe</subfield><subfield code="z">9781461348429</subfield></datafield><datafield tag="776" ind1="0" ind2="8"><subfield code="i">Erscheint auch als</subfield><subfield code="n">Druck-Ausgabe</subfield><subfield code="z">9780306477669</subfield></datafield><datafield tag="776" ind1="0" ind2="8"><subfield code="i">Erscheint auch als</subfield><subfield code="n">Druck-Ausgabe</subfield><subfield code="z">9781441992178</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.1007/978-1-4419-9216-1</subfield><subfield code="x">Verlag</subfield><subfield code="z">URL des Erstveröffentlichers</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-2-SME</subfield></datafield><datafield tag="940" ind1="1" ind2=" "><subfield code="q">ZDB-2-SME_1990/2004</subfield></datafield><datafield tag="999" ind1=" " ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-031526634</subfield></datafield><datafield tag="966" ind1="e" ind2=" "><subfield code="u">https://doi.org/10.1007/978-1-4419-9216-1</subfield><subfield code="l">UBR01</subfield><subfield code="p">ZDB-2-SME</subfield><subfield code="q">ZDB-2-SME_1990/2004</subfield><subfield code="x">Verlag</subfield><subfield code="3">Volltext</subfield></datafield></record></collection> |
| id | DE-604.BV046146449 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T08:36:30Z |
| institution | BVB |
| isbn | 9781441992161 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-031526634 |
| oclc_num | 1119113454 |
| open_access_boolean | |
| owner | DE-355 DE-BY-UBR |
| owner_facet | DE-355 DE-BY-UBR |
| physical | 1 Online-Ressource (XVI, 550 p) |
| psigel | ZDB-2-SME ZDB-2-SME_1990/2004 ZDB-2-SME ZDB-2-SME_1990/2004 |
| publishDate | 2004 |
| publishDateSearch | 2004 |
| publishDateSort | 2004 |
| publisher | Springer US |
| record_format | marc |
| spelling | Applications of Pharmacokinetic Principles in Drug Development edited by Rajesh Krishna Boston, MA Springer US 2004 1 Online-Ressource (XVI, 550 p) txt rdacontent c rdamedia cr rdacarrier This volume is an important advancement in the application ofpharmacokinetic (PK) and pharmacodynamic (PO) principles to . drug development. The series of topics presented deal with the application of these tools to everyday decisions that a pharmaceutical scientist encounters. The ability to integrate these topics using PK and PO methods has optimized drug development pathways in the clinic. New technologies in the areas of in vitro assays that are more predictive of human absorption and metabolism and advancement in bioanalytical assays are leading the way to minimize drug failures in later, more expensive clinical development programs. of Pharmacokinetics and pharmacodynamics have become an important component understanding the drug action on the body and is becoming increasingly important in drug labeling due to it's potential for predicting drug behavior in populations that may be difficult to study in adequate numbers during drug development. The ability to correlate drug exposure to effect and model it during the drug development value chain provides valuable insight into optimizing the next steps to derive maximum information from each study. These principles and modeling techniques have resulted in an expanded and integrated view of PK and PO and have led to the expectations that we may be able to optimally design clinical trials and eventually lead us to identifying the optimal therapy for the patient, while minimizing cost and speeding up drug development. There is wide utility for the book both as a text and as a reference Veterinary Medicine/Veterinary Science Biochemistry, general Pharmacy Evolutionary Biology Veterinary medicine Biochemistry Evolution (Biology) Krishna, Rajesh edt Erscheint auch als Druck-Ausgabe 9781461348429 Erscheint auch als Druck-Ausgabe 9780306477669 Erscheint auch als Druck-Ausgabe 9781441992178 https://doi.org/10.1007/978-1-4419-9216-1 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Applications of Pharmacokinetic Principles in Drug Development Veterinary Medicine/Veterinary Science Biochemistry, general Pharmacy Evolutionary Biology Veterinary medicine Biochemistry Evolution (Biology) |
| title | Applications of Pharmacokinetic Principles in Drug Development |
| title_auth | Applications of Pharmacokinetic Principles in Drug Development |
| title_exact_search | Applications of Pharmacokinetic Principles in Drug Development |
| title_full | Applications of Pharmacokinetic Principles in Drug Development edited by Rajesh Krishna |
| title_fullStr | Applications of Pharmacokinetic Principles in Drug Development edited by Rajesh Krishna |
| title_full_unstemmed | Applications of Pharmacokinetic Principles in Drug Development edited by Rajesh Krishna |
| title_short | Applications of Pharmacokinetic Principles in Drug Development |
| title_sort | applications of pharmacokinetic principles in drug development |
| topic | Veterinary Medicine/Veterinary Science Biochemistry, general Pharmacy Evolutionary Biology Veterinary medicine Biochemistry Evolution (Biology) |
| topic_facet | Veterinary Medicine/Veterinary Science Biochemistry, general Pharmacy Evolutionary Biology Veterinary medicine Biochemistry Evolution (Biology) |
| url | https://doi.org/10.1007/978-1-4419-9216-1 |
| work_keys_str_mv | AT krishnarajesh applicationsofpharmacokineticprinciplesindrugdevelopment |