Growth Factors and Wound Healing: Basic Science and Potential Clinical Applications
The biology of wound healing and tissue repair are increasingly being defined. At the same time, the availability of recombinant peptide growth factors for clinical investigation has prompted numerous trials of growth factor administration as adjunctive therapy to enhance the rate and quality of acu...
Gespeichert in:
| Weitere Verfasser: | , , |
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| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
New York, NY
Springer New York
1997
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| Schriftenreihe: | Serono Symposia USA
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| Schlagworte: | |
| Online-Zugang: | UBR01 Volltext |
| Zusammenfassung: | The biology of wound healing and tissue repair are increasingly being defined. At the same time, the availability of recombinant peptide growth factors for clinical investigation has prompted numerous trials of growth factor administration as adjunctive therapy to enhance the rate and quality of acute and chronic wound repair. New basic science information on growth factor function and regulation obtained in the research laboratory is actively being applied in animal studies and in clinical research settings. In addition to studies of surface wounds, an increasing number of investiga tions on growth factor administration have focused on healing and repair in nondermal tissues such as the intestinal tract and other organs. While the amount of new information on the molecular biology of growth factor expression, signaling, and function has been exponential in recent years, results of many clinical trials on growth factor administration in wound healing have been disappointing. This may be due, in part, to the heterogeneity of clinical wounds and the patients who harbor them, less than adequate standardization of care in experimental and control groups, issues related to drug dosing, and inadequate control for important issues relevant to healing such as nutrient intake and underlying nutritional status |
| Beschreibung: | 1 Online-Ressource (XVIII, 366 p) |
| ISBN: | 9781461218760 |
| DOI: | 10.1007/978-1-4612-1876-0 |
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| discipline | Medizin |
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| spelling | Growth Factors and Wound Healing Basic Science and Potential Clinical Applications edited by Thomas R. Ziegler, Glenn F. Pierce, David N. Herndon New York, NY Springer New York 1997 1 Online-Ressource (XVIII, 366 p) txt rdacontent c rdamedia cr rdacarrier Serono Symposia USA The biology of wound healing and tissue repair are increasingly being defined. At the same time, the availability of recombinant peptide growth factors for clinical investigation has prompted numerous trials of growth factor administration as adjunctive therapy to enhance the rate and quality of acute and chronic wound repair. New basic science information on growth factor function and regulation obtained in the research laboratory is actively being applied in animal studies and in clinical research settings. In addition to studies of surface wounds, an increasing number of investiga tions on growth factor administration have focused on healing and repair in nondermal tissues such as the intestinal tract and other organs. While the amount of new information on the molecular biology of growth factor expression, signaling, and function has been exponential in recent years, results of many clinical trials on growth factor administration in wound healing have been disappointing. This may be due, in part, to the heterogeneity of clinical wounds and the patients who harbor them, less than adequate standardization of care in experimental and control groups, issues related to drug dosing, and inadequate control for important issues relevant to healing such as nutrient intake and underlying nutritional status Surgery Endocrinology Wundheilung (DE-588)4138713-2 gnd rswk-swf Wachstumsfaktor (DE-588)4188802-9 gnd rswk-swf (DE-588)1071861417 Konferenzschrift 1995 Boston Mass. gnd-content Wundheilung (DE-588)4138713-2 s Wachstumsfaktor (DE-588)4188802-9 s DE-604 Ziegler, Thomas R. edt Pierce, Glenn F. edt Herndon, David N. edt Erscheint auch als Druck-Ausgabe 9780387949680 Erscheint auch als Druck-Ausgabe 9781461273219 Erscheint auch als Druck-Ausgabe 9781461218777 https://doi.org/10.1007/978-1-4612-1876-0 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Growth Factors and Wound Healing Basic Science and Potential Clinical Applications Surgery Endocrinology Wundheilung (DE-588)4138713-2 gnd Wachstumsfaktor (DE-588)4188802-9 gnd |
| subject_GND | (DE-588)4138713-2 (DE-588)4188802-9 (DE-588)1071861417 |
| title | Growth Factors and Wound Healing Basic Science and Potential Clinical Applications |
| title_auth | Growth Factors and Wound Healing Basic Science and Potential Clinical Applications |
| title_exact_search | Growth Factors and Wound Healing Basic Science and Potential Clinical Applications |
| title_full | Growth Factors and Wound Healing Basic Science and Potential Clinical Applications edited by Thomas R. Ziegler, Glenn F. Pierce, David N. Herndon |
| title_fullStr | Growth Factors and Wound Healing Basic Science and Potential Clinical Applications edited by Thomas R. Ziegler, Glenn F. Pierce, David N. Herndon |
| title_full_unstemmed | Growth Factors and Wound Healing Basic Science and Potential Clinical Applications edited by Thomas R. Ziegler, Glenn F. Pierce, David N. Herndon |
| title_short | Growth Factors and Wound Healing |
| title_sort | growth factors and wound healing basic science and potential clinical applications |
| title_sub | Basic Science and Potential Clinical Applications |
| topic | Surgery Endocrinology Wundheilung (DE-588)4138713-2 gnd Wachstumsfaktor (DE-588)4188802-9 gnd |
| topic_facet | Surgery Endocrinology Wundheilung Wachstumsfaktor Konferenzschrift 1995 Boston Mass. |
| url | https://doi.org/10.1007/978-1-4612-1876-0 |
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