Late Graft Loss: Proceedings of the 28th Conference on Transplantation and Clinical Immunology, 3–5 June, 1996
In all varieties of organ transplants, early results have dramatically improved over the past two decades and failures due to acute rejection are becoming rarer. Efficient immunosuppressive regimens have been developed with the objective of very good results at 1, 3 and 5 years. Successful transplan...
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| Weitere Verfasser: | , , , |
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| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Dordrecht
Springer Netherlands
1997
|
| Schriftenreihe: | Transplantation and Clinical Immunology
28 |
| Schlagworte: | |
| Online-Zugang: | UBR01 Volltext |
| Zusammenfassung: | In all varieties of organ transplants, early results have dramatically improved over the past two decades and failures due to acute rejection are becoming rarer. Efficient immunosuppressive regimens have been developed with the objective of very good results at 1, 3 and 5 years. Successful transplants, however, are significantly less frequent at 10 and 20 years, and many patients require retransplantation. Many factors are involved in late graft loss and it is now well recognized that, in addition to chronic rejection, a number of non-immunologic factors play a prominent role. In the case of renal transplantation, a reduced mass loss (transplantation of a single kidney, sometimes from an aged donor, ischemic injury and alteration of some nephrons in the case of early acute rejection) will result in slowly progressing chronic renal failure, even in the absence of any supplementary attack of an immunological nature. The new treatments must be analyzed in the light of their capacity to reduce these late failures. Several preventive measures can also limit both immunologic and non-immunologic factors of late transplant deterioration |
| Beschreibung: | 1 Online-Ressource (XVI, 239 p) |
| ISBN: | 9789401154345 |
| DOI: | 10.1007/978-94-011-5434-5 |
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| 520 | |a In all varieties of organ transplants, early results have dramatically improved over the past two decades and failures due to acute rejection are becoming rarer. Efficient immunosuppressive regimens have been developed with the objective of very good results at 1, 3 and 5 years. Successful transplants, however, are significantly less frequent at 10 and 20 years, and many patients require retransplantation. Many factors are involved in late graft loss and it is now well recognized that, in addition to chronic rejection, a number of non-immunologic factors play a prominent role. In the case of renal transplantation, a reduced mass loss (transplantation of a single kidney, sometimes from an aged donor, ischemic injury and alteration of some nephrons in the case of early acute rejection) will result in slowly progressing chronic renal failure, even in the absence of any supplementary attack of an immunological nature. The new treatments must be analyzed in the light of their capacity to reduce these late failures. Several preventive measures can also limit both immunologic and non-immunologic factors of late transplant deterioration | ||
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| spelling | Late Graft Loss Proceedings of the 28th Conference on Transplantation and Clinical Immunology, 3–5 June, 1996 edited by J. L. Touraine, J. Traeger, H. Bétuel, J. M. Dubernard, J. P. Revillard, C. Dupuy Dordrecht Springer Netherlands 1997 1 Online-Ressource (XVI, 239 p) txt rdacontent c rdamedia cr rdacarrier Transplantation and Clinical Immunology 28 In all varieties of organ transplants, early results have dramatically improved over the past two decades and failures due to acute rejection are becoming rarer. Efficient immunosuppressive regimens have been developed with the objective of very good results at 1, 3 and 5 years. Successful transplants, however, are significantly less frequent at 10 and 20 years, and many patients require retransplantation. Many factors are involved in late graft loss and it is now well recognized that, in addition to chronic rejection, a number of non-immunologic factors play a prominent role. In the case of renal transplantation, a reduced mass loss (transplantation of a single kidney, sometimes from an aged donor, ischemic injury and alteration of some nephrons in the case of early acute rejection) will result in slowly progressing chronic renal failure, even in the absence of any supplementary attack of an immunological nature. The new treatments must be analyzed in the light of their capacity to reduce these late failures. Several preventive measures can also limit both immunologic and non-immunologic factors of late transplant deterioration Nephrology Transplant Surgery Immunology Transplantation of organs, tissu Transplantatabstoßung (DE-588)4137807-6 gnd rswk-swf (DE-588)1071861417 Konferenzschrift 1996 Lyon gnd-content Transplantatabstoßung (DE-588)4137807-6 s DE-604 Touraine, Jean-Louis 1945- (DE-588)1157371272 edt Traeger, J. edt Bétuel, H. edt Dubernard, J. M. edt Erscheint auch als Druck-Ausgabe 9789401062862 Erscheint auch als Druck-Ausgabe 9780792343158 Erscheint auch als Druck-Ausgabe 9789401154352 https://doi.org/10.1007/978-94-011-5434-5 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Late Graft Loss Proceedings of the 28th Conference on Transplantation and Clinical Immunology, 3–5 June, 1996 Nephrology Transplant Surgery Immunology Transplantation of organs, tissu Transplantatabstoßung (DE-588)4137807-6 gnd |
| subject_GND | (DE-588)4137807-6 (DE-588)1071861417 |
| title | Late Graft Loss Proceedings of the 28th Conference on Transplantation and Clinical Immunology, 3–5 June, 1996 |
| title_auth | Late Graft Loss Proceedings of the 28th Conference on Transplantation and Clinical Immunology, 3–5 June, 1996 |
| title_exact_search | Late Graft Loss Proceedings of the 28th Conference on Transplantation and Clinical Immunology, 3–5 June, 1996 |
| title_full | Late Graft Loss Proceedings of the 28th Conference on Transplantation and Clinical Immunology, 3–5 June, 1996 edited by J. L. Touraine, J. Traeger, H. Bétuel, J. M. Dubernard, J. P. Revillard, C. Dupuy |
| title_fullStr | Late Graft Loss Proceedings of the 28th Conference on Transplantation and Clinical Immunology, 3–5 June, 1996 edited by J. L. Touraine, J. Traeger, H. Bétuel, J. M. Dubernard, J. P. Revillard, C. Dupuy |
| title_full_unstemmed | Late Graft Loss Proceedings of the 28th Conference on Transplantation and Clinical Immunology, 3–5 June, 1996 edited by J. L. Touraine, J. Traeger, H. Bétuel, J. M. Dubernard, J. P. Revillard, C. Dupuy |
| title_short | Late Graft Loss |
| title_sort | late graft loss proceedings of the 28th conference on transplantation and clinical immunology 3 5 june 1996 |
| title_sub | Proceedings of the 28th Conference on Transplantation and Clinical Immunology, 3–5 June, 1996 |
| topic | Nephrology Transplant Surgery Immunology Transplantation of organs, tissu Transplantatabstoßung (DE-588)4137807-6 gnd |
| topic_facet | Nephrology Transplant Surgery Immunology Transplantation of organs, tissu Transplantatabstoßung Konferenzschrift 1996 Lyon |
| url | https://doi.org/10.1007/978-94-011-5434-5 |
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