Evolving Concepts in Sepsis and Septic Shock:
Much research over the past 30 to 40 years has shown that the inflammatory response, while critical for host defense during microbial infection, may itself play a central role in the pathogenesis of sepsis. Although key mediators responsible for this injury have been identified, efforts clinically t...
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Boston, MA
Springer US
2001
|
| Schriftenreihe: | Perspectives on Critical Care Infectious Diseases
2 |
| Schlagworte: | |
| Online-Zugang: | UBR01 URL des Erstveröffentlichers |
| Zusammenfassung: | Much research over the past 30 to 40 years has shown that the inflammatory response, while critical for host defense during microbial infection, may itself play a central role in the pathogenesis of sepsis. Although key mediators responsible for this injury have been identified, efforts clinically to augment our conventional antimicrobial and supportive therapies during sepsis with agents modulating the inflammatory response have been unsuccessful. As a result, the mortality associated with this lethal syndrome, especially when complicated by shock, has remained persistently high. Unfortunately, during this same period of time, the incidence of sepsis has accelerated as other fields of medicine have relied increasingly on therapies that predispose to infection. While frustrating, overall this experience in the field of sepsis has not been without value. Most importantly, it has helped define on several different levels the complexity of the septic patient. Recognizing and addressing this complexity as discussed by each of the contributors to Evolving Concepts in Sepsis and Septic Shock may now provide new inroads into the treatment of sepsis |
| Beschreibung: | 1 Online-Ressource (XII, 195 p) |
| ISBN: | 9781461515814 |
| DOI: | 10.1007/978-1-4615-1581-4 |
Internformat
MARC
| LEADER | 00000nmm a2200000zcb4500 | ||
|---|---|---|---|
| 001 | BV046146090 | ||
| 003 | DE-604 | ||
| 005 | 00000000000000.0 | ||
| 007 | cr|uuu---uuuuu | ||
| 008 | 190905s2001 |||| o||u| ||||||eng d | ||
| 020 | |a 9781461515814 |9 978-1-4615-1581-4 | ||
| 024 | 7 | |a 10.1007/978-1-4615-1581-4 |2 doi | |
| 035 | |a (ZDB-2-SME)978-1-4615-1581-4 | ||
| 035 | |a (OCoLC)1119008754 | ||
| 035 | |a (DE-599)BVBBV046146090 | ||
| 040 | |a DE-604 |b ger |e aacr | ||
| 041 | 0 | |a eng | |
| 049 | |a DE-355 | ||
| 082 | 0 | |a 616.028 |2 23 | |
| 084 | |a YD 3015 |0 (DE-625)153297:12921 |2 rvk | ||
| 245 | 1 | 0 | |a Evolving Concepts in Sepsis and Septic Shock |c edited by Peter Q. Eichacker, Jérôme Pugin |
| 264 | 1 | |a Boston, MA |b Springer US |c 2001 | |
| 300 | |a 1 Online-Ressource (XII, 195 p) | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b c |2 rdamedia | ||
| 338 | |b cr |2 rdacarrier | ||
| 490 | 0 | |a Perspectives on Critical Care Infectious Diseases |v 2 | |
| 520 | |a Much research over the past 30 to 40 years has shown that the inflammatory response, while critical for host defense during microbial infection, may itself play a central role in the pathogenesis of sepsis. Although key mediators responsible for this injury have been identified, efforts clinically to augment our conventional antimicrobial and supportive therapies during sepsis with agents modulating the inflammatory response have been unsuccessful. As a result, the mortality associated with this lethal syndrome, especially when complicated by shock, has remained persistently high. Unfortunately, during this same period of time, the incidence of sepsis has accelerated as other fields of medicine have relied increasingly on therapies that predispose to infection. While frustrating, overall this experience in the field of sepsis has not been without value. Most importantly, it has helped define on several different levels the complexity of the septic patient. Recognizing and addressing this complexity as discussed by each of the contributors to Evolving Concepts in Sepsis and Septic Shock may now provide new inroads into the treatment of sepsis | ||
| 650 | 4 | |a Intensive / Critical Care Medicine | |
| 650 | 4 | |a Pneumology/Respiratory System | |
| 650 | 4 | |a Infectious Diseases | |
| 650 | 4 | |a Medical Microbiology | |
| 650 | 4 | |a Critical care medicine | |
| 650 | 4 | |a Pneumology | |
| 650 | 4 | |a Emerging infectious diseases | |
| 650 | 4 | |a Microbiology | |
| 650 | 0 | 7 | |a Septischer Schock |0 (DE-588)4193151-8 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Therapie |0 (DE-588)4059798-2 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Sepsis |0 (DE-588)4181014-4 |2 gnd |9 rswk-swf |
| 689 | 0 | 0 | |a Septischer Schock |0 (DE-588)4193151-8 |D s |
| 689 | 0 | 1 | |a Therapie |0 (DE-588)4059798-2 |D s |
| 689 | 0 | |8 1\p |5 DE-604 | |
| 689 | 1 | 0 | |a Sepsis |0 (DE-588)4181014-4 |D s |
| 689 | 1 | 1 | |a Therapie |0 (DE-588)4059798-2 |D s |
| 689 | 1 | |8 2\p |5 DE-604 | |
| 700 | 1 | |a Eichacker, Peter Q. |4 edt | |
| 700 | 1 | |a Pugin, Jérôme |4 edt | |
| 776 | 0 | 8 | |i Erscheint auch als |n Druck-Ausgabe |z 9780792372356 |
| 776 | 0 | 8 | |i Erscheint auch als |n Druck-Ausgabe |z 9781461356257 |
| 776 | 0 | 8 | |i Erscheint auch als |n Druck-Ausgabe |z 9781461515821 |
| 856 | 4 | 0 | |u https://doi.org/10.1007/978-1-4615-1581-4 |x Verlag |z URL des Erstveröffentlichers |3 Volltext |
| 912 | |a ZDB-2-SME | ||
| 940 | 1 | |q ZDB-2-SME_1990/2004 | |
| 999 | |a oai:aleph.bib-bvb.de:BVB01-031526275 | ||
| 883 | 1 | |8 1\p |a cgwrk |d 20201028 |q DE-101 |u https://d-nb.info/provenance/plan#cgwrk | |
| 883 | 1 | |8 2\p |a cgwrk |d 20201028 |q DE-101 |u https://d-nb.info/provenance/plan#cgwrk | |
| 966 | e | |u https://doi.org/10.1007/978-1-4615-1581-4 |l UBR01 |p ZDB-2-SME |q ZDB-2-SME_1990/2004 |x Verlag |3 Volltext | |
Datensatz im Suchindex
| _version_ | 1804180483603431424 |
|---|---|
| any_adam_object | |
| author2 | Eichacker, Peter Q. Pugin, Jérôme |
| author2_role | edt edt |
| author2_variant | p q e pq pqe j p jp |
| author_facet | Eichacker, Peter Q. Pugin, Jérôme |
| building | Verbundindex |
| bvnumber | BV046146090 |
| classification_rvk | YD 3015 |
| collection | ZDB-2-SME |
| ctrlnum | (ZDB-2-SME)978-1-4615-1581-4 (OCoLC)1119008754 (DE-599)BVBBV046146090 |
| dewey-full | 616.028 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 616 - Diseases |
| dewey-raw | 616.028 |
| dewey-search | 616.028 |
| dewey-sort | 3616.028 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| doi_str_mv | 10.1007/978-1-4615-1581-4 |
| format | Electronic eBook |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>03612nmm a2200649zcb4500</leader><controlfield tag="001">BV046146090</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">00000000000000.0</controlfield><controlfield tag="007">cr|uuu---uuuuu</controlfield><controlfield tag="008">190905s2001 |||| o||u| ||||||eng d</controlfield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9781461515814</subfield><subfield code="9">978-1-4615-1581-4</subfield></datafield><datafield tag="024" ind1="7" ind2=" "><subfield code="a">10.1007/978-1-4615-1581-4</subfield><subfield code="2">doi</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(ZDB-2-SME)978-1-4615-1581-4</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)1119008754</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV046146090</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">aacr</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-355</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">616.028</subfield><subfield code="2">23</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">YD 3015</subfield><subfield code="0">(DE-625)153297:12921</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Evolving Concepts in Sepsis and Septic Shock</subfield><subfield code="c">edited by Peter Q. Eichacker, Jérôme Pugin</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Boston, MA</subfield><subfield code="b">Springer US</subfield><subfield code="c">2001</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 Online-Ressource (XII, 195 p)</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="490" ind1="0" ind2=" "><subfield code="a">Perspectives on Critical Care Infectious Diseases</subfield><subfield code="v">2</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Much research over the past 30 to 40 years has shown that the inflammatory response, while critical for host defense during microbial infection, may itself play a central role in the pathogenesis of sepsis. Although key mediators responsible for this injury have been identified, efforts clinically to augment our conventional antimicrobial and supportive therapies during sepsis with agents modulating the inflammatory response have been unsuccessful. As a result, the mortality associated with this lethal syndrome, especially when complicated by shock, has remained persistently high. Unfortunately, during this same period of time, the incidence of sepsis has accelerated as other fields of medicine have relied increasingly on therapies that predispose to infection. While frustrating, overall this experience in the field of sepsis has not been without value. Most importantly, it has helped define on several different levels the complexity of the septic patient. Recognizing and addressing this complexity as discussed by each of the contributors to Evolving Concepts in Sepsis and Septic Shock may now provide new inroads into the treatment of sepsis</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Intensive / Critical Care Medicine</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Pneumology/Respiratory System</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Infectious Diseases</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Medical Microbiology</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Critical care medicine</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Pneumology</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Emerging infectious diseases</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Microbiology</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Septischer Schock</subfield><subfield code="0">(DE-588)4193151-8</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Therapie</subfield><subfield code="0">(DE-588)4059798-2</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Sepsis</subfield><subfield code="0">(DE-588)4181014-4</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="689" ind1="0" ind2="0"><subfield code="a">Septischer Schock</subfield><subfield code="0">(DE-588)4193151-8</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="1"><subfield code="a">Therapie</subfield><subfield code="0">(DE-588)4059798-2</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2=" "><subfield code="8">1\p</subfield><subfield code="5">DE-604</subfield></datafield><datafield tag="689" ind1="1" ind2="0"><subfield code="a">Sepsis</subfield><subfield code="0">(DE-588)4181014-4</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="1" ind2="1"><subfield code="a">Therapie</subfield><subfield code="0">(DE-588)4059798-2</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="1" ind2=" "><subfield code="8">2\p</subfield><subfield code="5">DE-604</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Eichacker, Peter Q.</subfield><subfield code="4">edt</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Pugin, Jérôme</subfield><subfield code="4">edt</subfield></datafield><datafield tag="776" ind1="0" ind2="8"><subfield code="i">Erscheint auch als</subfield><subfield code="n">Druck-Ausgabe</subfield><subfield code="z">9780792372356</subfield></datafield><datafield tag="776" ind1="0" ind2="8"><subfield code="i">Erscheint auch als</subfield><subfield code="n">Druck-Ausgabe</subfield><subfield code="z">9781461356257</subfield></datafield><datafield tag="776" ind1="0" ind2="8"><subfield code="i">Erscheint auch als</subfield><subfield code="n">Druck-Ausgabe</subfield><subfield code="z">9781461515821</subfield></datafield><datafield tag="856" ind1="4" ind2="0"><subfield code="u">https://doi.org/10.1007/978-1-4615-1581-4</subfield><subfield code="x">Verlag</subfield><subfield code="z">URL des Erstveröffentlichers</subfield><subfield code="3">Volltext</subfield></datafield><datafield tag="912" ind1=" " ind2=" "><subfield code="a">ZDB-2-SME</subfield></datafield><datafield tag="940" ind1="1" ind2=" "><subfield code="q">ZDB-2-SME_1990/2004</subfield></datafield><datafield tag="999" ind1=" " ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-031526275</subfield></datafield><datafield tag="883" ind1="1" ind2=" "><subfield code="8">1\p</subfield><subfield code="a">cgwrk</subfield><subfield code="d">20201028</subfield><subfield code="q">DE-101</subfield><subfield code="u">https://d-nb.info/provenance/plan#cgwrk</subfield></datafield><datafield tag="883" ind1="1" ind2=" "><subfield code="8">2\p</subfield><subfield code="a">cgwrk</subfield><subfield code="d">20201028</subfield><subfield code="q">DE-101</subfield><subfield code="u">https://d-nb.info/provenance/plan#cgwrk</subfield></datafield><datafield tag="966" ind1="e" ind2=" "><subfield code="u">https://doi.org/10.1007/978-1-4615-1581-4</subfield><subfield code="l">UBR01</subfield><subfield code="p">ZDB-2-SME</subfield><subfield code="q">ZDB-2-SME_1990/2004</subfield><subfield code="x">Verlag</subfield><subfield code="3">Volltext</subfield></datafield></record></collection> |
| id | DE-604.BV046146090 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-10T08:36:29Z |
| institution | BVB |
| isbn | 9781461515814 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-031526275 |
| oclc_num | 1119008754 |
| open_access_boolean | |
| owner | DE-355 DE-BY-UBR |
| owner_facet | DE-355 DE-BY-UBR |
| physical | 1 Online-Ressource (XII, 195 p) |
| psigel | ZDB-2-SME ZDB-2-SME_1990/2004 ZDB-2-SME ZDB-2-SME_1990/2004 |
| publishDate | 2001 |
| publishDateSearch | 2001 |
| publishDateSort | 2001 |
| publisher | Springer US |
| record_format | marc |
| series2 | Perspectives on Critical Care Infectious Diseases |
| spelling | Evolving Concepts in Sepsis and Septic Shock edited by Peter Q. Eichacker, Jérôme Pugin Boston, MA Springer US 2001 1 Online-Ressource (XII, 195 p) txt rdacontent c rdamedia cr rdacarrier Perspectives on Critical Care Infectious Diseases 2 Much research over the past 30 to 40 years has shown that the inflammatory response, while critical for host defense during microbial infection, may itself play a central role in the pathogenesis of sepsis. Although key mediators responsible for this injury have been identified, efforts clinically to augment our conventional antimicrobial and supportive therapies during sepsis with agents modulating the inflammatory response have been unsuccessful. As a result, the mortality associated with this lethal syndrome, especially when complicated by shock, has remained persistently high. Unfortunately, during this same period of time, the incidence of sepsis has accelerated as other fields of medicine have relied increasingly on therapies that predispose to infection. While frustrating, overall this experience in the field of sepsis has not been without value. Most importantly, it has helped define on several different levels the complexity of the septic patient. Recognizing and addressing this complexity as discussed by each of the contributors to Evolving Concepts in Sepsis and Septic Shock may now provide new inroads into the treatment of sepsis Intensive / Critical Care Medicine Pneumology/Respiratory System Infectious Diseases Medical Microbiology Critical care medicine Pneumology Emerging infectious diseases Microbiology Septischer Schock (DE-588)4193151-8 gnd rswk-swf Therapie (DE-588)4059798-2 gnd rswk-swf Sepsis (DE-588)4181014-4 gnd rswk-swf Septischer Schock (DE-588)4193151-8 s Therapie (DE-588)4059798-2 s 1\p DE-604 Sepsis (DE-588)4181014-4 s 2\p DE-604 Eichacker, Peter Q. edt Pugin, Jérôme edt Erscheint auch als Druck-Ausgabe 9780792372356 Erscheint auch als Druck-Ausgabe 9781461356257 Erscheint auch als Druck-Ausgabe 9781461515821 https://doi.org/10.1007/978-1-4615-1581-4 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 2\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Evolving Concepts in Sepsis and Septic Shock Intensive / Critical Care Medicine Pneumology/Respiratory System Infectious Diseases Medical Microbiology Critical care medicine Pneumology Emerging infectious diseases Microbiology Septischer Schock (DE-588)4193151-8 gnd Therapie (DE-588)4059798-2 gnd Sepsis (DE-588)4181014-4 gnd |
| subject_GND | (DE-588)4193151-8 (DE-588)4059798-2 (DE-588)4181014-4 |
| title | Evolving Concepts in Sepsis and Septic Shock |
| title_auth | Evolving Concepts in Sepsis and Septic Shock |
| title_exact_search | Evolving Concepts in Sepsis and Septic Shock |
| title_full | Evolving Concepts in Sepsis and Septic Shock edited by Peter Q. Eichacker, Jérôme Pugin |
| title_fullStr | Evolving Concepts in Sepsis and Septic Shock edited by Peter Q. Eichacker, Jérôme Pugin |
| title_full_unstemmed | Evolving Concepts in Sepsis and Septic Shock edited by Peter Q. Eichacker, Jérôme Pugin |
| title_short | Evolving Concepts in Sepsis and Septic Shock |
| title_sort | evolving concepts in sepsis and septic shock |
| topic | Intensive / Critical Care Medicine Pneumology/Respiratory System Infectious Diseases Medical Microbiology Critical care medicine Pneumology Emerging infectious diseases Microbiology Septischer Schock (DE-588)4193151-8 gnd Therapie (DE-588)4059798-2 gnd Sepsis (DE-588)4181014-4 gnd |
| topic_facet | Intensive / Critical Care Medicine Pneumology/Respiratory System Infectious Diseases Medical Microbiology Critical care medicine Pneumology Emerging infectious diseases Microbiology Septischer Schock Therapie Sepsis |
| url | https://doi.org/10.1007/978-1-4615-1581-4 |
| work_keys_str_mv | AT eichackerpeterq evolvingconceptsinsepsisandsepticshock AT puginjerome evolvingconceptsinsepsisandsepticshock |