Regulatory Mechanisms in Breast Cancer: Advances in Cellular and Molecular Biology of Breast Cancer
In Breast Cancer: Cellular and Molecular Biology [Kluwer Academic Pub lishers, 1988], we tried to present an introduction to the emerging basic studies on steroid receptors, oncogenes, and growth factors in the regulation of normal and malignant mammary epithelium. The response to this volume was s...
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Boston, MA
Springer US
1991
|
| Schriftenreihe: | Cancer Treatment and Research
53 |
| Schlagworte: | |
| Online-Zugang: | UBR01 URL des Erstveröffentlichers |
| Zusammenfassung: | In Breast Cancer: Cellular and Molecular Biology [Kluwer Academic Pub lishers, 1988], we tried to present an introduction to the emerging basic studies on steroid receptors, oncogenes, and growth factors in the regulation of normal and malignant mammary epithelium. The response to this volume was superb, indicating a tremendous interest in basic growth regulatory mechanisms governing breast cancer and controlling its malignant progres sion. In the two years since its publication, much new and exciting in formation has been published and the full interplay of regulatory mechanisms is now beginning to emerge. We have divided this book into four sections that we hope will unify important concepts and help to crystallize areas of consensus and/or disagreement among a diverse group of basic and clinical scientists working on the disease. The first section is devoted to studies on oncogenes, antioncogenes, proliferation, and tumor prognosis. The first chapter, by Sunderland and McGuire, introduces the characteristics of breast cancer as studied by patho logists to establish prognostic outcome. Of particular interest is a new proto oncogene called HER-2 (or neu), which is rapidly becoming accepted as a valuable new tumor marker of poor prognosis. The second chapter, by Lee Bookstein and Lee, introduces the best known antioncogene, the retinoblas toma antioncogene, whose expression is sometimes lost in breast cancer. Malignant progression appears to be influenced by the balance of proto oncogene and antioncogene expression |
| Beschreibung: | 1 Online-Ressource (IV, 452 p) |
| ISBN: | 9781461539407 |
| DOI: | 10.1007/978-1-4615-3940-7 |
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Datensatz im Suchindex
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| any_adam_object | |
| author2 | Lippman, Marc E. Dickson, Robert B. |
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| author_facet | Lippman, Marc E. Dickson, Robert B. |
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| dewey-full | 616.994 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 616 - Diseases |
| dewey-raw | 616.994 |
| dewey-search | 616.994 |
| dewey-sort | 3616.994 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| doi_str_mv | 10.1007/978-1-4615-3940-7 |
| format | Electronic eBook |
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| indexdate | 2024-07-10T08:36:28Z |
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| physical | 1 Online-Ressource (IV, 452 p) |
| psigel | ZDB-2-SME ZDB-2-SME_1990/2004 ZDB-2-SME ZDB-2-SME_1990/2004 |
| publishDate | 1991 |
| publishDateSearch | 1991 |
| publishDateSort | 1991 |
| publisher | Springer US |
| record_format | marc |
| series2 | Cancer Treatment and Research |
| spelling | Regulatory Mechanisms in Breast Cancer Advances in Cellular and Molecular Biology of Breast Cancer edited by Marc E. Lippman, Robert B. Dickson Boston, MA Springer US 1991 1 Online-Ressource (IV, 452 p) txt rdacontent c rdamedia cr rdacarrier Cancer Treatment and Research 53 In Breast Cancer: Cellular and Molecular Biology [Kluwer Academic Pub lishers, 1988], we tried to present an introduction to the emerging basic studies on steroid receptors, oncogenes, and growth factors in the regulation of normal and malignant mammary epithelium. The response to this volume was superb, indicating a tremendous interest in basic growth regulatory mechanisms governing breast cancer and controlling its malignant progres sion. In the two years since its publication, much new and exciting in formation has been published and the full interplay of regulatory mechanisms is now beginning to emerge. We have divided this book into four sections that we hope will unify important concepts and help to crystallize areas of consensus and/or disagreement among a diverse group of basic and clinical scientists working on the disease. The first section is devoted to studies on oncogenes, antioncogenes, proliferation, and tumor prognosis. The first chapter, by Sunderland and McGuire, introduces the characteristics of breast cancer as studied by patho logists to establish prognostic outcome. Of particular interest is a new proto oncogene called HER-2 (or neu), which is rapidly becoming accepted as a valuable new tumor marker of poor prognosis. The second chapter, by Lee Bookstein and Lee, introduces the best known antioncogene, the retinoblas toma antioncogene, whose expression is sometimes lost in breast cancer. Malignant progression appears to be influenced by the balance of proto oncogene and antioncogene expression Oncology Cancer Research Oncology Cytologie (DE-588)4070177-3 gnd rswk-swf Wachstumsfaktor (DE-588)4188802-9 gnd rswk-swf Molekularbiologie (DE-588)4039983-7 gnd rswk-swf Wachstumsregulation (DE-588)4188805-4 gnd rswk-swf Östrogenrezeptor (DE-588)4172467-7 gnd rswk-swf Onkogen (DE-588)4131118-8 gnd rswk-swf Brustkrebs (DE-588)4008528-4 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Brustkrebs (DE-588)4008528-4 s Wachstumsregulation (DE-588)4188805-4 s Onkogen (DE-588)4131118-8 s 1\p DE-604 Östrogenrezeptor (DE-588)4172467-7 s 2\p DE-604 Wachstumsfaktor (DE-588)4188802-9 s 3\p DE-604 4\p DE-604 Cytologie (DE-588)4070177-3 s 5\p DE-604 Molekularbiologie (DE-588)4039983-7 s DE-604 Lippman, Marc E. edt Dickson, Robert B. edt Erscheint auch als Druck-Ausgabe 9781461367581 Erscheint auch als Druck-Ausgabe 9780792308683 Erscheint auch als Druck-Ausgabe 9781461539414 https://doi.org/10.1007/978-1-4615-3940-7 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 2\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 3\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 4\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 5\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Regulatory Mechanisms in Breast Cancer Advances in Cellular and Molecular Biology of Breast Cancer Oncology Cancer Research Oncology Cytologie (DE-588)4070177-3 gnd Wachstumsfaktor (DE-588)4188802-9 gnd Molekularbiologie (DE-588)4039983-7 gnd Wachstumsregulation (DE-588)4188805-4 gnd Östrogenrezeptor (DE-588)4172467-7 gnd Onkogen (DE-588)4131118-8 gnd Brustkrebs (DE-588)4008528-4 gnd |
| subject_GND | (DE-588)4070177-3 (DE-588)4188802-9 (DE-588)4039983-7 (DE-588)4188805-4 (DE-588)4172467-7 (DE-588)4131118-8 (DE-588)4008528-4 (DE-588)4143413-4 |
| title | Regulatory Mechanisms in Breast Cancer Advances in Cellular and Molecular Biology of Breast Cancer |
| title_auth | Regulatory Mechanisms in Breast Cancer Advances in Cellular and Molecular Biology of Breast Cancer |
| title_exact_search | Regulatory Mechanisms in Breast Cancer Advances in Cellular and Molecular Biology of Breast Cancer |
| title_full | Regulatory Mechanisms in Breast Cancer Advances in Cellular and Molecular Biology of Breast Cancer edited by Marc E. Lippman, Robert B. Dickson |
| title_fullStr | Regulatory Mechanisms in Breast Cancer Advances in Cellular and Molecular Biology of Breast Cancer edited by Marc E. Lippman, Robert B. Dickson |
| title_full_unstemmed | Regulatory Mechanisms in Breast Cancer Advances in Cellular and Molecular Biology of Breast Cancer edited by Marc E. Lippman, Robert B. Dickson |
| title_short | Regulatory Mechanisms in Breast Cancer |
| title_sort | regulatory mechanisms in breast cancer advances in cellular and molecular biology of breast cancer |
| title_sub | Advances in Cellular and Molecular Biology of Breast Cancer |
| topic | Oncology Cancer Research Oncology Cytologie (DE-588)4070177-3 gnd Wachstumsfaktor (DE-588)4188802-9 gnd Molekularbiologie (DE-588)4039983-7 gnd Wachstumsregulation (DE-588)4188805-4 gnd Östrogenrezeptor (DE-588)4172467-7 gnd Onkogen (DE-588)4131118-8 gnd Brustkrebs (DE-588)4008528-4 gnd |
| topic_facet | Oncology Cancer Research Oncology Cytologie Wachstumsfaktor Molekularbiologie Wachstumsregulation Östrogenrezeptor Onkogen Brustkrebs Aufsatzsammlung |
| url | https://doi.org/10.1007/978-1-4615-3940-7 |
| work_keys_str_mv | AT lippmanmarce regulatorymechanismsinbreastcanceradvancesincellularandmolecularbiologyofbreastcancer AT dicksonrobertb regulatorymechanismsinbreastcanceradvancesincellularandmolecularbiologyofbreastcancer |