Verfügbarkeit: Male Sterility and Motility Disorders

Male Sterility and Motility Disorders: Etiological Factors and Treatment

This conference, dedicated to the etiology and treatment of motility disor ders in spermatozoa and male sterility, attracted some of the finest investiga tors in the field. Standards were immensely high throughout, and discussions were meaningful and detailed. Analyses on disorders in sperm motili...

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Weitere Verfasser:	Hamamah, Samir (HerausgeberIn), Olivennes, François (HerausgeberIn), Mieusset, Roger (HerausgeberIn), Frydman, René (HerausgeberIn)
Format:	Elektronisch E-Book
Sprache:	English
Veröffentlicht:	New York, NY Springer New York 1999
Schriftenreihe:	Serono Symposia USA
Schlagworte:	Obstetrics/Perinatology/Midwifery Obstetrics Motilitätsstörung Spermium Mann Sterilität Konferenzschrift > 1998 > Paris
Online-Zugang:	UBR01 Volltext Inhaltsverzeichnis
Zusammenfassung:	This conference, dedicated to the etiology and treatment of motility disor ders in spermatozoa and male sterility, attracted some of the finest investiga tors in the field. Standards were immensely high throughout, and discussions were meaningful and detailed. Analyses on disorders in sperm motility de mand a broad-based approach, involving cytologists, geneticists, andrologists, and embryologists, because the topic has many clinical and scientific over tones. Human spermatozoa are at the mercy of so many factors as they form and mature in the testis and epididymis. Their survival and fundamental char acteristics are essential for fertilization, and the male genome imposes its influence on the embryo as it becomes active in male pronuclei very soon after sperm entry into the oocyte. All of these fundamental aspects of sperm biology demanded a broad breadth of topics in the symposium. The opening session quickly got down to fundamentals with contributions from J.-L. Gatti, J.G. Alvarez, C. Gagnon, and H. Breitbart. They discussed the mechanism and regulation of motility, the metabolic strategy of human spermatozoa, the effects of exogenous fac tors such as antibodies, infections, and toxins, and finally the role of intracel lular calcium on sperm motility. To these topics, the postcoffee session on the first morning described the genetics of motility disorders and the etiology and management of necrozoospermia. The excellent presentation provided the background detail of the symposium and opened the way for the discus sion of various clinical aspects of the topic
Beschreibung:	1 Online-Ressource (XX, 320 p)
ISBN:	9781461215226
DOI:	10.1007/978-1-4612-1522-6

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Datensatz im Suchindex

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adam_text	INHALTSVERZEICHNIS DANKSAGUNG I KURZFASSUNG III ABSTRACT IV INHALTSVERZEICHNIS V 1 EINFUEHRUNG 1 1.1 MOTIVATION UN D Z IELSETZU N G ............................................................... 3 1.2 L ITE RA TU RUE B E RB LIC K ............................................................................... 8 1.3 AUFBAU UN D G LIE D E RU N G ...................................................................... 9 2 PKW-GETRIEBE 11 2.1 UE BERSICHT PKW-GETRIEBE ................................................................... 11 2.2 HANDSCHALTGETRIEBE ............................................................................ 12 2.2.1 K U P P LU N G ................................................................................... 14 2.2.2 TEM PERATUREIGENSCHAFTEN DER K U P P L U N G ......................... 16 2.2.3 S Y N C H RO N IS IE RU N G ......................................... 18 2.3 AUTOM ATISIERTES H A N D SC H ALTG ETRIEB E................................................ 22 2.4 D OPPELKUPPLUNGSGETRIEBE............................................................ 24 2.5 K URZZUSAM M ENFASSUNG KAPITEL 2 ................................................... 27 3 MODELLBILDUNG GETRIEBE 29 3.1 LITERATURUEBERBLICK G E TRIE B E M O D E LLE ................................................ 31 3.2 G ETRIE B EM O D ELLIERU N G ......................................................................... 34 3.2.1 GRUNDLAGEN DER M E C H A N I K ................................................... 34 3.2.2 M ODELLSTRUKTUR A S G ................................................................ 39 3.2.3 KUPPLUNGSMODELL ................................................................... 41 3.3 G ETRIEB EAK TU ATO RIK ............................................................................... 42 3.3.1 HYDRAULISCHE G RU N D LA G EN ...................................................... 42 3.3.2 K U P P LU N G SSTELLER...................................................................... 44 3.4 TEM PERATURM ODELL DER KUPPLUNG ................................................... 45 3.5 K URZZUSAM M ENFASSUNG KAPITEL 3 ................................................... 48 4 ENTWICKLUNG DER VERSUCHSUMGEBUNG 51 4.1 AUFBAU U N D F U N K TIO N S W E IS E ............................................................. 52 4.1.1 M ECHANISCHER A U F B A U ............................................................. 53 4.1.2 ELEKTRISCHER A U F B A U ................................................................ 54 4.1.3 F U N K TIO N SW EISE.......................................................................... 54 4.2 FUNKTIONALE S I C H E R H E I T ...................................................................... 56 4.3 P RUE FSTA N D SA U TO M A TISIE RU N G ................................................................ 56 4.4 M E S S TE C H N IK .......................................................................................... 58 4.4.1 M E SSD A TE N SY N C H RO N ISIE RU N G ................................................ 58 4.4.2 SENSORIK UND M ESSD ATEN V ERARB EITU N G ................................ 59 4.5 ENTWICKLUNG EINES P RUE FSTAN D SM O D ELLS............................................. 62 4.5.1 EXPERIM ENTELLE P A RA M E TE RB E S TIM M U N G ............................. 62 4.5.1.1 BESTIM M UNG DER R EIBUNGSEIGENSCHAFTEN .... 62 4.5.1.2 B ESTIM M UNG DER Z EITKONSTANTEN DER ELEKTRISCHEN M A S C H IN E N ................................................................ 63 4.5.1.3 B ESTIM M UNG DER SIGNALLAUFZEIT .......................... 64 4.5.2 M ODELLAUFBAU DES P R UE F S TA N D E S ............................................. 65 4.5.3 BEISPIELANWENDUNG: SIM ULATION K UPPLUNGSVERSUCH . . . 66 4.6 K URZZUSAM M ENFASSUNG KAPITEL 4 ................................................... 67 5 METHODENAUSWAHL 69 5.1 A UTOM ATISIERTE P A RA M E TE RFIN D U N G .................................................. 70 5.2 AUSWAHL EINER IDENTIFIKATIONSM ETHODE .......................................... 71 5.3 NEURONALE N E T Z E ................................................................................... 73 5.3.1 EINGESETZTE NEURONALE N E T Z E ................................................ 73 5.3.2 L E RN A LG O RITH M U S ...................................................................... 78 5.4 S TRU K TU RIERTE R EKURRENTE NEURONALE N E T Z E ................................... 79 5.4.1 MODELLIERUNG IM Z U S T A N D S R A U M .......................................... 79 5.4.2 LERNGESETZ FUER DAS S R N N ...................................................... 81 5.4.3 BEIPIELANWENDUNG: ELEKTRISCHE M A S C H IN E .......................... 83 5.5 ERW EITERUNG AU F ZWEIDIMENSIONALE P RO B LE M E ................................ 90 5.6 K URZZUSAM M ENFASSUNG KAPITEL 5 ................................................... 96 6 IDENTIFIKATION DER GETRIEBEPARAMETER 99 6.1 IDENTIFIKATION A N TRIE B S M A S C H IN E N ................................................... 99 6.2 IDENTIFIKATION E IN M A SSE N SC H W U N G RA D ............................................. 102 6.2.1 V E RS U C H S B E S C H RE IB U N G .......................................................... 103 6.2.2 ERGEBNISSE DER T RAE G H EITSB ESTIM M U N G ................................ 104 6.2.3 K URZZUSAM M ENFASSUNG E IN M A SSE N SC H W U N G RA D ............. 106 6.3 IDENTIFIKATION DER KUPPLUNG ............................................................ 107 6.3.1 K U P P LU N G S A K TU A TO R................................................................ 108 6.3.2 T O RSIO N SFE D ER ............................................................................ 110 6.3.3 K U P P LU N G SK A P A Z ITAE T................................................................ 112 6.3.3.1 V E RS U C H S A U FB A U ...................................................... 113 6.3.3.2 V E RSU C H SD U RC H FUE H RU N G ......................................... 114 6.3.4 K URZZUSAM M ENFASSUNG K U P P LU N G ...................................... 117 6.4 IDENTIFIKATION DER R E I B U N G ................................................................ 118 6.4.1 V E RS U C H S B E S C H RE IB U N G ......................................................... 119 6.4.2 ERGEBNISSE DER R EIBUNGS-UND TRAEGHEITSBESTIM M UNG . . 121 6.4.3 K URZZUSAM M ENFASSUNG L A G E RRE IB U N G ................................ 123 6.5 IDENTIFIKATION DES V E RZ A H N U N G SSP IE LS............................................. 123 6.5.1 K URZZUSAM M ENFASSUNG L O S E ................................................ 126 7 VALIDIERUNG DES MODELLS 127 7.1 VERGLEICH MIT DEM A SG -M ODELL ......................................................... 127 7.1.1 VERGLEICH STATIONAERER B E TRIE B S P U N K TE ................................ 128 7.1.2 VERGLEICH DYNAM ISCHER V E RSU C H E .......................................... 130 7.1.3 A USSAGEKRAFT DES PARAM ETRIERTEN GETRIEBEMODELLS . . . . 131 7.2 ANWENDUNG AU F EIN D OPPELKUPPLUNGSGETRIEBEM ODELL ................ 132 7.2.1 K UPPLUNGSKAPAZITAET D K G ...................................................... 132 7.2.2 IDENTIFIKATION REIBMOMENT D K G ......................................... 135 7.2.3 ERGEBNISSE DER ID E N TIFIK A TIO N ................................................ 136 7.3 ALLGEMEINE BEWERTUNG DES M O D E LLFE H LE RS ...................................... 138 7.4 K URZZUSAM M ENFASSUNG KAPITEL 7 ................................................... 139 8 ZUSAMMENFASSUNG UND SCHLUSSFOLGERUNGEN 141 ABKUERZUNGSVERZEICHNIS 146 NOMENKLATUR 149 ABBILDUNGSVERZEICHNIS 153 TABELLENVERZEICHNIS 156 A ANHANG KAPITEL 4 159 A. 1 PROGRAMMBEISPIEL M ESSD ATE N SY N C H RO N ISA TIO N ............................ 159 A. 2 FORMELN S IG N A LV E RA RB E ITU N G ............................................................ 160 B ANHANG KAPITEL 5 161 B . L BESTIM M UNG DER REIBUNG DURCH STATISCHE B ETRIEBSPUNKTE . . . 161 B.2 HERLEITUNG DER PARTIELLEN A B LE ITU N G E N ............................................ 162 B.2.1 EINDIM ENSIONALER F A L L ............................................................ 163 B.2.2 ZWEIDIMENSIONALER F A L L ......................................................... 166 B.3 PARAM ETERDIM ENSIONEN DER S R N N .................................................. 175 C ANHANG KAPITEL 6 177 C .L EXPERIM ENTELLE B ESTIM M UNG DER G E TRIE B E RE IB U N G ....................... 177 C.2 EXPERIM ENTELLE B ESTIM M UNG DER FEDERSTEIFIGKEIT .......................... 178 C.3 U NTERSUCHUNG DER V E RD RE H STE IFIG K E IT............................................. 179 LITERATURVERZEICHNIS 183 EIGENE U N D BETREUTE A R B E I T E N ....................................................................... 213
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publishDate	1999
publishDateSearch	1999
publishDateSort	1999
publisher	Springer New York
record_format	marc
series2	Serono Symposia USA
spelling	Male Sterility and Motility Disorders Etiological Factors and Treatment edited by Samir Hamamah, François Olivennes, Roger Mieusset, René Frydman New York, NY Springer New York 1999 1 Online-Ressource (XX, 320 p) txt rdacontent c rdamedia cr rdacarrier Serono Symposia USA This conference, dedicated to the etiology and treatment of motility disor ders in spermatozoa and male sterility, attracted some of the finest investiga tors in the field. Standards were immensely high throughout, and discussions were meaningful and detailed. Analyses on disorders in sperm motility de mand a broad-based approach, involving cytologists, geneticists, andrologists, and embryologists, because the topic has many clinical and scientific over tones. Human spermatozoa are at the mercy of so many factors as they form and mature in the testis and epididymis. Their survival and fundamental char acteristics are essential for fertilization, and the male genome imposes its influence on the embryo as it becomes active in male pronuclei very soon after sperm entry into the oocyte. All of these fundamental aspects of sperm biology demanded a broad breadth of topics in the symposium. The opening session quickly got down to fundamentals with contributions from J.-L. Gatti, J.G. Alvarez, C. Gagnon, and H. Breitbart. They discussed the mechanism and regulation of motility, the metabolic strategy of human spermatozoa, the effects of exogenous fac tors such as antibodies, infections, and toxins, and finally the role of intracel lular calcium on sperm motility. To these topics, the postcoffee session on the first morning described the genetics of motility disorders and the etiology and management of necrozoospermia. The excellent presentation provided the background detail of the symposium and opened the way for the discus sion of various clinical aspects of the topic Obstetrics/Perinatology/Midwifery Obstetrics Motilitätsstörung (DE-588)4276912-7 gnd rswk-swf Spermium (DE-588)4135383-3 gnd rswk-swf Mann (DE-588)4037363-0 gnd rswk-swf Sterilität (DE-588)4057338-2 gnd rswk-swf (DE-588)1071861417 Konferenzschrift 1998 Paris gnd-content Mann (DE-588)4037363-0 s Sterilität (DE-588)4057338-2 s Spermium (DE-588)4135383-3 s Motilitätsstörung (DE-588)4276912-7 s DE-604 Hamamah, Samir edt Olivennes, François edt Mieusset, Roger edt Frydman, René edt Erscheint auch als Druck-Ausgabe 9780387986739 Erscheint auch als Druck-Ausgabe 9781461271772 Erscheint auch als Druck-Ausgabe 9781461215233 https://doi.org/10.1007/978-1-4612-1522-6 Verlag URL des Erstveröffentlichers Volltext DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=031525902&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis
spellingShingle	Male Sterility and Motility Disorders Etiological Factors and Treatment Obstetrics/Perinatology/Midwifery Obstetrics Motilitätsstörung (DE-588)4276912-7 gnd Spermium (DE-588)4135383-3 gnd Mann (DE-588)4037363-0 gnd Sterilität (DE-588)4057338-2 gnd
subject_GND	(DE-588)4276912-7 (DE-588)4135383-3 (DE-588)4037363-0 (DE-588)4057338-2 (DE-588)1071861417
title	Male Sterility and Motility Disorders Etiological Factors and Treatment
title_auth	Male Sterility and Motility Disorders Etiological Factors and Treatment
title_exact_search	Male Sterility and Motility Disorders Etiological Factors and Treatment
title_full	Male Sterility and Motility Disorders Etiological Factors and Treatment edited by Samir Hamamah, François Olivennes, Roger Mieusset, René Frydman
title_fullStr	Male Sterility and Motility Disorders Etiological Factors and Treatment edited by Samir Hamamah, François Olivennes, Roger Mieusset, René Frydman
title_full_unstemmed	Male Sterility and Motility Disorders Etiological Factors and Treatment edited by Samir Hamamah, François Olivennes, Roger Mieusset, René Frydman
title_short	Male Sterility and Motility Disorders
title_sort	male sterility and motility disorders etiological factors and treatment
title_sub	Etiological Factors and Treatment
topic	Obstetrics/Perinatology/Midwifery Obstetrics Motilitätsstörung (DE-588)4276912-7 gnd Spermium (DE-588)4135383-3 gnd Mann (DE-588)4037363-0 gnd Sterilität (DE-588)4057338-2 gnd
topic_facet	Obstetrics/Perinatology/Midwifery Obstetrics Motilitätsstörung Spermium Mann Sterilität Konferenzschrift 1998 Paris
url	https://doi.org/10.1007/978-1-4612-1522-6 http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=031525902&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA
work_keys_str_mv	AT hamamahsamir malesterilityandmotilitydisordersetiologicalfactorsandtreatment AT olivennesfrancois malesterilityandmotilitydisordersetiologicalfactorsandtreatment AT mieussetroger malesterilityandmotilitydisordersetiologicalfactorsandtreatment AT frydmanrene malesterilityandmotilitydisordersetiologicalfactorsandtreatment

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