Biology and Physiology of the Blood-Brain Barrier: Transport, Cellular Interactions, and Brain Pathologies
The endothelial cells of the cerebral vasculature constitute, together with perivascular elements (astrocytes, pcricytes, basement membrane), the blood-brain barrier (BBB), which strictly limits and specifically controls the exchanges between the blood and the cerebral extracellular spacc.The existe...
Gespeichert in:
| Weitere Verfasser: | , |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Boston, MA
Springer US
1996
|
| Schriftenreihe: | Advances in Behavioral Biology
46 |
| Schlagworte: | |
| Online-Zugang: | UBR01 URL des Erstveröffentlichers |
| Zusammenfassung: | The endothelial cells of the cerebral vasculature constitute, together with perivascular elements (astrocytes, pcricytes, basement membrane), the blood-brain barrier (BBB), which strictly limits and specifically controls the exchanges between the blood and the cerebral extracellular spacc.The existence of such a physical, enzymatic, and active barrier isolating the central nervous system has broad physiological, biological, pharmacological, and patho logical consequences, most of which are not yet fully elucidated. The Cerebral Vascular Biology conference (CVB '95) was organized and held at the "Carre des Sciences" in Paris on July I 0-12, 1995. Like the CVB '92 conference held in Duluth, Minnesota, three years ago, the objectives were to provide a forum for presentation of the most recent progresses and to stimulate discussions in the ticld of the biology, physiology. and pathology of the blood-brain barrier. The Paris conference gathered more than !50 participants. including investigators in basic neuroscience, physicians. and stu dents, who actively contributed to the scientific program by their oral or poster presentations. This volume contains a collection of short articles that summarize most of the new data that were presented at the conference. Six thematic parts focus on physiological transports. drug delivery, multidrug resistance P-glycoprotein, signal transduction at the BBB. interactions between the immune system and the cerebral endothelial cells, and the blood-brain barrier-related pathologies in the central nervous system. In addition, two introductory articles present new insights in the rapidly evolving topics of cerebral angiogenesis and gene transfer to the brain |
| Beschreibung: | 1 Online-Ressource (XVI, 388 p) |
| ISBN: | 9781475794892 |
| DOI: | 10.1007/978-1-4757-9489-2 |
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| 520 | |a The endothelial cells of the cerebral vasculature constitute, together with perivascular elements (astrocytes, pcricytes, basement membrane), the blood-brain barrier (BBB), which strictly limits and specifically controls the exchanges between the blood and the cerebral extracellular spacc.The existence of such a physical, enzymatic, and active barrier isolating the central nervous system has broad physiological, biological, pharmacological, and patho logical consequences, most of which are not yet fully elucidated. The Cerebral Vascular Biology conference (CVB '95) was organized and held at the "Carre des Sciences" in Paris on July I 0-12, 1995. Like the CVB '92 conference held in Duluth, Minnesota, three years ago, the objectives were to provide a forum for presentation of the most recent progresses and to stimulate discussions in the ticld of the biology, physiology. and pathology of the blood-brain barrier. The Paris conference gathered more than !50 participants. including investigators in basic neuroscience, physicians. and stu dents, who actively contributed to the scientific program by their oral or poster presentations. This volume contains a collection of short articles that summarize most of the new data that were presented at the conference. Six thematic parts focus on physiological transports. drug delivery, multidrug resistance P-glycoprotein, signal transduction at the BBB. interactions between the immune system and the cerebral endothelial cells, and the blood-brain barrier-related pathologies in the central nervous system. In addition, two introductory articles present new insights in the rapidly evolving topics of cerebral angiogenesis and gene transfer to the brain | ||
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| spelling | Biology and Physiology of the Blood-Brain Barrier Transport, Cellular Interactions, and Brain Pathologies edited by Pierre-Olivier Couraud, Daniel Scherman Proceedings of the Cerebral Vascular Biology Symposium held in Paris, France, July 10-12, 1995 Boston, MA Springer US 1996 1 Online-Ressource (XVI, 388 p) txt rdacontent c rdamedia cr rdacarrier Advances in Behavioral Biology 46 The endothelial cells of the cerebral vasculature constitute, together with perivascular elements (astrocytes, pcricytes, basement membrane), the blood-brain barrier (BBB), which strictly limits and specifically controls the exchanges between the blood and the cerebral extracellular spacc.The existence of such a physical, enzymatic, and active barrier isolating the central nervous system has broad physiological, biological, pharmacological, and patho logical consequences, most of which are not yet fully elucidated. The Cerebral Vascular Biology conference (CVB '95) was organized and held at the "Carre des Sciences" in Paris on July I 0-12, 1995. Like the CVB '92 conference held in Duluth, Minnesota, three years ago, the objectives were to provide a forum for presentation of the most recent progresses and to stimulate discussions in the ticld of the biology, physiology. and pathology of the blood-brain barrier. The Paris conference gathered more than !50 participants. including investigators in basic neuroscience, physicians. and stu dents, who actively contributed to the scientific program by their oral or poster presentations. This volume contains a collection of short articles that summarize most of the new data that were presented at the conference. Six thematic parts focus on physiological transports. drug delivery, multidrug resistance P-glycoprotein, signal transduction at the BBB. interactions between the immune system and the cerebral endothelial cells, and the blood-brain barrier-related pathologies in the central nervous system. In addition, two introductory articles present new insights in the rapidly evolving topics of cerebral angiogenesis and gene transfer to the brain Neurology Neurosurgery Pathology Animal Anatomy / Morphology / Histology Plant Sciences Animal Physiology Morphology (Animals) Botany Animal physiology Blut-Hirn-Schranke (DE-588)4007279-4 gnd rswk-swf (DE-588)1071861417 Konferenzschrift 1995 Paris gnd-content Blut-Hirn-Schranke (DE-588)4007279-4 s DE-604 Couraud, Pierre-Olivier edt Scherman, Daniel edt Erscheint auch als Druck-Ausgabe 9781475794915 Erscheint auch als Druck-Ausgabe 9780306453625 Erscheint auch als Druck-Ausgabe 9781475794908 https://doi.org/10.1007/978-1-4757-9489-2 Verlag URL des Erstveröffentlichers Volltext |
| spellingShingle | Biology and Physiology of the Blood-Brain Barrier Transport, Cellular Interactions, and Brain Pathologies Neurology Neurosurgery Pathology Animal Anatomy / Morphology / Histology Plant Sciences Animal Physiology Morphology (Animals) Botany Animal physiology Blut-Hirn-Schranke (DE-588)4007279-4 gnd |
| subject_GND | (DE-588)4007279-4 (DE-588)1071861417 |
| title | Biology and Physiology of the Blood-Brain Barrier Transport, Cellular Interactions, and Brain Pathologies |
| title_alt | Proceedings of the Cerebral Vascular Biology Symposium held in Paris, France, July 10-12, 1995 |
| title_auth | Biology and Physiology of the Blood-Brain Barrier Transport, Cellular Interactions, and Brain Pathologies |
| title_exact_search | Biology and Physiology of the Blood-Brain Barrier Transport, Cellular Interactions, and Brain Pathologies |
| title_full | Biology and Physiology of the Blood-Brain Barrier Transport, Cellular Interactions, and Brain Pathologies edited by Pierre-Olivier Couraud, Daniel Scherman |
| title_fullStr | Biology and Physiology of the Blood-Brain Barrier Transport, Cellular Interactions, and Brain Pathologies edited by Pierre-Olivier Couraud, Daniel Scherman |
| title_full_unstemmed | Biology and Physiology of the Blood-Brain Barrier Transport, Cellular Interactions, and Brain Pathologies edited by Pierre-Olivier Couraud, Daniel Scherman |
| title_short | Biology and Physiology of the Blood-Brain Barrier |
| title_sort | biology and physiology of the blood brain barrier transport cellular interactions and brain pathologies |
| title_sub | Transport, Cellular Interactions, and Brain Pathologies |
| topic | Neurology Neurosurgery Pathology Animal Anatomy / Morphology / Histology Plant Sciences Animal Physiology Morphology (Animals) Botany Animal physiology Blut-Hirn-Schranke (DE-588)4007279-4 gnd |
| topic_facet | Neurology Neurosurgery Pathology Animal Anatomy / Morphology / Histology Plant Sciences Animal Physiology Morphology (Animals) Botany Animal physiology Blut-Hirn-Schranke Konferenzschrift 1995 Paris |
| url | https://doi.org/10.1007/978-1-4757-9489-2 |
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