Myocardial Ischemia and Preconditioning:
Current evidence suggests that the ischemic preconditioning response is a multi-factorial process consisting of an initial early trigger, an intermediate mediator, and an end effector. Each of these steps in is now its own intense area of investigation. The need to render the heart ischemic for a br...
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Weitere Verfasser: | , , , |
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Format: | Elektronisch E-Book |
Sprache: | English |
Veröffentlicht: |
Boston, MA
Springer US
2003
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Schriftenreihe: | Progress in Experimental Cardiology
6 |
Schlagworte: | |
Online-Zugang: | UBR01 Volltext |
Zusammenfassung: | Current evidence suggests that the ischemic preconditioning response is a multi-factorial process consisting of an initial early trigger, an intermediate mediator, and an end effector. Each of these steps in is now its own intense area of investigation. The need to render the heart ischemic for a brief period to invoke the preconditioning response is currently the major factor limiting clinical application of this powerful cardioprotective strategy. Recent research efforts have utilized brief exposures to pharmacological agents, in lieu of a brief preconditioning ischemia, to trigger/mimic the ischemic preconditioning-induced response. The World Heart Congress held in Winnipeg in July 2001 provided a forum for the presentation of new insights into the basic mechanisms of ischemia and reperfusion injury, as well as novel strategies to protect the heart from cell death, ventricular arrhythmias, and contractile dysfunction. Many pioneers in the fields of ischemia-reperfusion injury and preconditioning-induced protection presented there and the chapters in this book represent selected papers from these symposia |
Beschreibung: | 1 Online-Ressource (XVII, 541 p) |
ISBN: | 9781461503552 |
DOI: | 10.1007/978-1-4615-0355-2 |
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institution | BVB |
isbn | 9781461503552 |
language | English |
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spelling | Myocardial Ischemia and Preconditioning edited by Naranjan S. Dhalla, Nobuakira Takeda, Manjeet Singh, Anton Lukas Boston, MA Springer US 2003 1 Online-Ressource (XVII, 541 p) txt rdacontent c rdamedia cr rdacarrier Progress in Experimental Cardiology 6 Current evidence suggests that the ischemic preconditioning response is a multi-factorial process consisting of an initial early trigger, an intermediate mediator, and an end effector. Each of these steps in is now its own intense area of investigation. The need to render the heart ischemic for a brief period to invoke the preconditioning response is currently the major factor limiting clinical application of this powerful cardioprotective strategy. Recent research efforts have utilized brief exposures to pharmacological agents, in lieu of a brief preconditioning ischemia, to trigger/mimic the ischemic preconditioning-induced response. The World Heart Congress held in Winnipeg in July 2001 provided a forum for the presentation of new insights into the basic mechanisms of ischemia and reperfusion injury, as well as novel strategies to protect the heart from cell death, ventricular arrhythmias, and contractile dysfunction. Many pioneers in the fields of ischemia-reperfusion injury and preconditioning-induced protection presented there and the chapters in this book represent selected papers from these symposia Cardiology Herzkrankheit (DE-588)4024663-2 gnd rswk-swf Ischämie (DE-588)4162456-7 gnd rswk-swf Herzkrankheit (DE-588)4024663-2 s Ischämie (DE-588)4162456-7 s 1\p DE-604 Dhalla, Naranjan S. edt Takeda, Nobuakira edt Singh, Manjeet edt Lukas, Anton edt Erscheint auch als Druck-Ausgabe 9781402071959 Erscheint auch als Druck-Ausgabe 9781461350361 Erscheint auch als Druck-Ausgabe 9781461503569 https://doi.org/10.1007/978-1-4615-0355-2 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
spellingShingle | Myocardial Ischemia and Preconditioning Cardiology Herzkrankheit (DE-588)4024663-2 gnd Ischämie (DE-588)4162456-7 gnd |
subject_GND | (DE-588)4024663-2 (DE-588)4162456-7 |
title | Myocardial Ischemia and Preconditioning |
title_auth | Myocardial Ischemia and Preconditioning |
title_exact_search | Myocardial Ischemia and Preconditioning |
title_full | Myocardial Ischemia and Preconditioning edited by Naranjan S. Dhalla, Nobuakira Takeda, Manjeet Singh, Anton Lukas |
title_fullStr | Myocardial Ischemia and Preconditioning edited by Naranjan S. Dhalla, Nobuakira Takeda, Manjeet Singh, Anton Lukas |
title_full_unstemmed | Myocardial Ischemia and Preconditioning edited by Naranjan S. Dhalla, Nobuakira Takeda, Manjeet Singh, Anton Lukas |
title_short | Myocardial Ischemia and Preconditioning |
title_sort | myocardial ischemia and preconditioning |
topic | Cardiology Herzkrankheit (DE-588)4024663-2 gnd Ischämie (DE-588)4162456-7 gnd |
topic_facet | Cardiology Herzkrankheit Ischämie |
url | https://doi.org/10.1007/978-1-4615-0355-2 |
work_keys_str_mv | AT dhallanaranjans myocardialischemiaandpreconditioning AT takedanobuakira myocardialischemiaandpreconditioning AT singhmanjeet myocardialischemiaandpreconditioning AT lukasanton myocardialischemiaandpreconditioning |