Imaging of Hypoxia: Tracer Developments
Hypoxia, i.e. insufficient availability of oxygen within the tissue, is a more serious problem than realized in clinical routine work, although a large variety of theoretical and experimental data give clearly proven indications. During incidences and progress of many types of diseases hypoxia may e...
Gespeichert in:
| Weitere Verfasser: | |
|---|---|
| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Dordrecht
Springer Netherlands
1999
|
| Schriftenreihe: | Developments in Nuclear Medicine
33 |
| Schlagworte: | |
| Online-Zugang: | UBR01 URL des Erstveröffentlichers |
| Zusammenfassung: | Hypoxia, i.e. insufficient availability of oxygen within the tissue, is a more serious problem than realized in clinical routine work, although a large variety of theoretical and experimental data give clearly proven indications. During incidences and progress of many types of diseases hypoxia may enhance development and progress of the disease and, furthermore, decrease chances of efficient treatment of, e.g., tumors. Hypoxic tumor cells are up to three times more resistant towards radiation therapy than normoxic cells. With a diagnostic tool such as provided by hypoxia tracers suitable for PET and SPECT imaging, the particular tissue situation becomes detectable and, thus, treatable. Although the clinical importance of hypoxia imaging is obviously great, to date neither the clinical nor the scientific community at an international level has focused many research activities on the hypoxia problem. As the result of a workshop held by the Section for Radiopharmacy in Tübingen, this book collects observations and findings in order to stimulate the on-going research resulting in important clinical applications. Hypoxia imaging is needed in areas of cardiology, neurology and oncology. Additional applications are to be expected in the field of diabetes, infections and organ transplantation. Therefore, the book addresses those who are basically involved in research in radiochemistry and radiopharmacy as well as those dealing with all biological aspects and facing direct clinical applications |
| Beschreibung: | 1 Online-Ressource (XX, 180 p) |
| ISBN: | 9789401718288 |
| DOI: | 10.1007/978-94-017-1828-8 |
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| 520 | |a Hypoxia, i.e. insufficient availability of oxygen within the tissue, is a more serious problem than realized in clinical routine work, although a large variety of theoretical and experimental data give clearly proven indications. During incidences and progress of many types of diseases hypoxia may enhance development and progress of the disease and, furthermore, decrease chances of efficient treatment of, e.g., tumors. Hypoxic tumor cells are up to three times more resistant towards radiation therapy than normoxic cells. With a diagnostic tool such as provided by hypoxia tracers suitable for PET and SPECT imaging, the particular tissue situation becomes detectable and, thus, treatable. Although the clinical importance of hypoxia imaging is obviously great, to date neither the clinical nor the scientific community at an international level has focused many research activities on the hypoxia problem. As the result of a workshop held by the Section for Radiopharmacy in Tübingen, this book collects observations and findings in order to stimulate the on-going research resulting in important clinical applications. Hypoxia imaging is needed in areas of cardiology, neurology and oncology. Additional applications are to be expected in the field of diabetes, infections and organ transplantation. Therefore, the book addresses those who are basically involved in research in radiochemistry and radiopharmacy as well as those dealing with all biological aspects and facing direct clinical applications | ||
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Datensatz im Suchindex
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| spelling | Imaging of Hypoxia Tracer Developments edited by Hans-Jürgen Machulla Dordrecht Springer Netherlands 1999 1 Online-Ressource (XX, 180 p) txt rdacontent c rdamedia cr rdacarrier Developments in Nuclear Medicine 33 Hypoxia, i.e. insufficient availability of oxygen within the tissue, is a more serious problem than realized in clinical routine work, although a large variety of theoretical and experimental data give clearly proven indications. During incidences and progress of many types of diseases hypoxia may enhance development and progress of the disease and, furthermore, decrease chances of efficient treatment of, e.g., tumors. Hypoxic tumor cells are up to three times more resistant towards radiation therapy than normoxic cells. With a diagnostic tool such as provided by hypoxia tracers suitable for PET and SPECT imaging, the particular tissue situation becomes detectable and, thus, treatable. Although the clinical importance of hypoxia imaging is obviously great, to date neither the clinical nor the scientific community at an international level has focused many research activities on the hypoxia problem. As the result of a workshop held by the Section for Radiopharmacy in Tübingen, this book collects observations and findings in order to stimulate the on-going research resulting in important clinical applications. Hypoxia imaging is needed in areas of cardiology, neurology and oncology. Additional applications are to be expected in the field of diabetes, infections and organ transplantation. Therefore, the book addresses those who are basically involved in research in radiochemistry and radiopharmacy as well as those dealing with all biological aspects and facing direct clinical applications Nuclear Medicine Radiotherapy Imaging / Radiology Nuclear medicine Radiology, Medical Radioindikator (DE-588)4176829-2 gnd rswk-swf Hypoxie (DE-588)4133549-1 gnd rswk-swf 1\p (DE-588)4143413-4 Aufsatzsammlung gnd-content 2\p (DE-588)1071861417 Konferenzschrift gnd-content Hypoxie (DE-588)4133549-1 s Radioindikator (DE-588)4176829-2 s 3\p DE-604 Machulla, Hans-Jürgen edt Erscheint auch als Druck-Ausgabe 9789048151578 Erscheint auch als Druck-Ausgabe 9780792355298 Erscheint auch als Druck-Ausgabe 9789401718295 https://doi.org/10.1007/978-94-017-1828-8 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 2\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 3\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Imaging of Hypoxia Tracer Developments Nuclear Medicine Radiotherapy Imaging / Radiology Nuclear medicine Radiology, Medical Radioindikator (DE-588)4176829-2 gnd Hypoxie (DE-588)4133549-1 gnd |
| subject_GND | (DE-588)4176829-2 (DE-588)4133549-1 (DE-588)4143413-4 (DE-588)1071861417 |
| title | Imaging of Hypoxia Tracer Developments |
| title_auth | Imaging of Hypoxia Tracer Developments |
| title_exact_search | Imaging of Hypoxia Tracer Developments |
| title_full | Imaging of Hypoxia Tracer Developments edited by Hans-Jürgen Machulla |
| title_fullStr | Imaging of Hypoxia Tracer Developments edited by Hans-Jürgen Machulla |
| title_full_unstemmed | Imaging of Hypoxia Tracer Developments edited by Hans-Jürgen Machulla |
| title_short | Imaging of Hypoxia |
| title_sort | imaging of hypoxia tracer developments |
| title_sub | Tracer Developments |
| topic | Nuclear Medicine Radiotherapy Imaging / Radiology Nuclear medicine Radiology, Medical Radioindikator (DE-588)4176829-2 gnd Hypoxie (DE-588)4133549-1 gnd |
| topic_facet | Nuclear Medicine Radiotherapy Imaging / Radiology Nuclear medicine Radiology, Medical Radioindikator Hypoxie Aufsatzsammlung Konferenzschrift |
| url | https://doi.org/10.1007/978-94-017-1828-8 |
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