The Neurology of Neuroblastoma: Neuroblastoma as a Neurobiological Disease
Neuroblastoma is the single most common solid tumor of childhood. Although children with small primary neuroblastomas alone are almost always cured by surgery, 65% of children with neuroblastoma already have large bulky tumors or metastatic disease by the time of initial diagnosis. For these childre...
Gespeichert in:
| 1. Verfasser: | |
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| Format: | Elektronisch E-Book |
| Sprache: | English |
| Veröffentlicht: |
Boston, MA
Springer US
2002
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| Schlagworte: | |
| Online-Zugang: | UBR01 URL des Erstveröffentlichers |
| Zusammenfassung: | Neuroblastoma is the single most common solid tumor of childhood. Although children with small primary neuroblastomas alone are almost always cured by surgery, 65% of children with neuroblastoma already have large bulky tumors or metastatic disease by the time of initial diagnosis. For these children, the 5-year survival rate is only somewhere between 5% and 20% with therapies including surgery, radiation, chemotherapy, and bone marrow transplantation. Dr Schor outlines a new approach to these tumors in order to make a difference for these children. There is much information to support the notion that neuroblastomas represent a developmental aberration of the nervous system, rather than a de novo abnormality in a previously normal cell. While the remote, paraneoplastic effects of neuroblastoma are often the purview of the child neurologist, the neoplasm itself has been viewed and approached therapeutically in much the same manner as all other solid tumors, as the purview of the pediatric oncologist. This work takes the view that approaching neuroblastoma rather as a disorder of nervous system development offers new therapeutic possibilities for this common tumor of childhood |
| Beschreibung: | 1 Online-Ressource (VII, 90 p) |
| ISBN: | 9781461510574 |
| DOI: | 10.1007/978-1-4615-1057-4 |
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| 520 | |a Neuroblastoma is the single most common solid tumor of childhood. Although children with small primary neuroblastomas alone are almost always cured by surgery, 65% of children with neuroblastoma already have large bulky tumors or metastatic disease by the time of initial diagnosis. For these children, the 5-year survival rate is only somewhere between 5% and 20% with therapies including surgery, radiation, chemotherapy, and bone marrow transplantation. Dr Schor outlines a new approach to these tumors in order to make a difference for these children. There is much information to support the notion that neuroblastomas represent a developmental aberration of the nervous system, rather than a de novo abnormality in a previously normal cell. While the remote, paraneoplastic effects of neuroblastoma are often the purview of the child neurologist, the neoplasm itself has been viewed and approached therapeutically in much the same manner as all other solid tumors, as the purview of the pediatric oncologist. This work takes the view that approaching neuroblastoma rather as a disorder of nervous system development offers new therapeutic possibilities for this common tumor of childhood | ||
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Datensatz im Suchindex
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| author | Schor, Nina Felice |
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| dewey-full | 616.8 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 616 - Diseases |
| dewey-raw | 616.8 |
| dewey-search | 616.8 |
| dewey-sort | 3616.8 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| doi_str_mv | 10.1007/978-1-4615-1057-4 |
| format | Electronic eBook |
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| isbn | 9781461510574 |
| language | English |
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| spelling | Schor, Nina Felice Verfasser aut The Neurology of Neuroblastoma Neuroblastoma as a Neurobiological Disease by Nina Felice Schor Boston, MA Springer US 2002 1 Online-Ressource (VII, 90 p) txt rdacontent c rdamedia cr rdacarrier Neuroblastoma is the single most common solid tumor of childhood. Although children with small primary neuroblastomas alone are almost always cured by surgery, 65% of children with neuroblastoma already have large bulky tumors or metastatic disease by the time of initial diagnosis. For these children, the 5-year survival rate is only somewhere between 5% and 20% with therapies including surgery, radiation, chemotherapy, and bone marrow transplantation. Dr Schor outlines a new approach to these tumors in order to make a difference for these children. There is much information to support the notion that neuroblastomas represent a developmental aberration of the nervous system, rather than a de novo abnormality in a previously normal cell. While the remote, paraneoplastic effects of neuroblastoma are often the purview of the child neurologist, the neoplasm itself has been viewed and approached therapeutically in much the same manner as all other solid tumors, as the purview of the pediatric oncologist. This work takes the view that approaching neuroblastoma rather as a disorder of nervous system development offers new therapeutic possibilities for this common tumor of childhood Neurology Neurosciences Oncology Cancer Research Oncology Neuroblastom (DE-588)4171578-0 gnd rswk-swf Neuroblastom (DE-588)4171578-0 s 1\p DE-604 Erscheint auch als Druck-Ausgabe 9781402071447 Erscheint auch als Druck-Ausgabe 9781461510581 Erscheint auch als Druck-Ausgabe 9781461353737 https://doi.org/10.1007/978-1-4615-1057-4 Verlag URL des Erstveröffentlichers Volltext 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Schor, Nina Felice The Neurology of Neuroblastoma Neuroblastoma as a Neurobiological Disease Neurology Neurosciences Oncology Cancer Research Oncology Neuroblastom (DE-588)4171578-0 gnd |
| subject_GND | (DE-588)4171578-0 |
| title | The Neurology of Neuroblastoma Neuroblastoma as a Neurobiological Disease |
| title_auth | The Neurology of Neuroblastoma Neuroblastoma as a Neurobiological Disease |
| title_exact_search | The Neurology of Neuroblastoma Neuroblastoma as a Neurobiological Disease |
| title_full | The Neurology of Neuroblastoma Neuroblastoma as a Neurobiological Disease by Nina Felice Schor |
| title_fullStr | The Neurology of Neuroblastoma Neuroblastoma as a Neurobiological Disease by Nina Felice Schor |
| title_full_unstemmed | The Neurology of Neuroblastoma Neuroblastoma as a Neurobiological Disease by Nina Felice Schor |
| title_short | The Neurology of Neuroblastoma |
| title_sort | the neurology of neuroblastoma neuroblastoma as a neurobiological disease |
| title_sub | Neuroblastoma as a Neurobiological Disease |
| topic | Neurology Neurosciences Oncology Cancer Research Oncology Neuroblastom (DE-588)4171578-0 gnd |
| topic_facet | Neurology Neurosciences Oncology Cancer Research Oncology Neuroblastom |
| url | https://doi.org/10.1007/978-1-4615-1057-4 |
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